MiR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency

EMBO Journal

Volumn 34, Issue 5, 2015, Pages 609-623

  Cao, Yang ^a   Guo, Wen Ting ^b   Tian, Shengya ^a   He, Xiaoping ^a   Wang, Xi Wen ^b   Liu, Xiaomeng ^b   Gu, Kai Li ^b   Ma, Xiaoyu ^a   Huang, De ^a   Hu, Lan ^a   Cai, Yongping ^c   Zhang, Huafeng ^a   Wang, Yangming ^b   Gao, Ping ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b PEKING UNIVERSITY   (China)

^c ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

glycolysis; Mbd2; metabolism; microRNA; pluripotency

Indexed keywords

GLYCOLYTIC ENZYME; LDHA ENZYME; METHYL CPG BINDING PROTEIN 2; MICRORNA; MICRORNA 290; MYC PROTEIN; PKM2 ENZYME; UNCLASSIFIED DRUG; DGCR8 PROTEIN, MOUSE; DNA BINDING PROTEIN; MBD2 PROTEIN, MOUSE; MIRN290 MICRORNA, MOUSE; MYC PROTEIN, MOUSE; PRIMER DNA; RNA BINDING PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CPG ISLAND; EMBRYONIC STEM CELL; ENZYME METABOLISM; FIBROBLAST; GLYCOLYSIS; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN METHYLATION; PROTEIN TARGETING; UPREGULATION; ANIMAL; CHROMATIN IMMUNOPRECIPITATION; ENZYMOLOGY; GENE INACTIVATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; DNA-BINDING PROTEINS; GENE KNOCKOUT TECHNIQUES; GLYCOLYSIS; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, KNOCKOUT; MICRORNAS; PLURIPOTENT STEM CELLS; PROTO-ONCOGENE PROTEINS C-MYC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS;

EID: 84924040113     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201490441     Document Type: Article

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