Exploring the transcription activator-like effectors scaffold versatility to expand the toolbox of designer nucleases

BMC Molecular Biology

Volumn 15, Issue , 2014, Pages

  Juillerat, Alexandre ^a   Beurdeley, Marine ^a   Valton, Julien ^a   Thomas, Séverine ^a   Dubois, Gwendoline ^a   Zaslavskiy, Mikhail ^a   Mikolajczak, Jérome ^a   Bietz, Fabian ^a   Silva, George H ^a   Duclert, Aymeric ^a   Daboussi, Fayza ^a   Duchateau, Philippe ^a  

^a Arvid Wallgrens Backe 20   (France)

Author keywords

Genome editing; Protein engineering; TALE; TALEN; Transcription activator like effectors

Indexed keywords

NUCLEASE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; DNA; ENDODEOXYRIBONUCLEASE FOKI; FUNGAL PROTEIN; HYBRID PROTEIN; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA HYBRIDIZATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; GENE LOCUS; GENE TECHNOLOGY; HUMAN; HUMAN CELL; MAMMAL CELL; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PROTEIN DNA BINDING; TRANSCRIPTION INITIATION; YEAST; ANIMAL; BINDING SITE; CELL LINE; CHEMISTRY; GENE TARGETING; GENETICS; METABOLISM; MOLECULAR GENETICS; PROCEDURES; PROTEIN ENGINEERING; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; DNA BINDING; DNA SEQUENCE; DNA STRAND; FUNGAL VIRULENCE; GENETIC TRANSFECTION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PROTEIN EXPRESSION;

MAMMALIA;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA; FUNGAL PROTEINS; GENE TARGETING; GENETIC LOCI; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; YEASTS;

EID: 84924031551     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-15-13     Document Type: Article

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