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Volumn 15, Issue 1, 2014, Pages

Lipid raft-based membrane order is important for antigen-specific clonal expansion of CD4 T lymphocytes

Author keywords

7 ketocholesterol; CD4+T cells; Cholesterol; Clonal expansion; Fluorescence resonance energy transfer; Lipid rafts; Membrane order

Indexed keywords

7 OXOCHOLESTEROL; BETA CYCLODEXTRIN; OVALBUMIN; T LYMPHOCYTE RECEPTOR; ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84923925111     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/s12865-014-0058-8     Document Type: Article
Times cited : (26)

References (65)
  • 4
    • 77952917698 scopus 로고    scopus 로고
    • Spatial organization of intracellular communication: insights from imaging
    • Dehmelt L, Bastiaens PI: Spatial organization of intracellular communication: insights from imaging. Nat Rev Mol Cell Biol 2010, 11:440-452.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 440-452
    • Dehmelt, L.1    Bastiaens, P.I.2
  • 5
    • 84876078880 scopus 로고    scopus 로고
    • Bioimage informatics for understanding spatiotemporal dynamics of cellular processes
    • Yang G: Bioimage informatics for understanding spatiotemporal dynamics of cellular processes. Wiley Interdiscip Rev Syst Biol Med 2013, 5:367-380.
    • (2013) Wiley Interdiscip Rev Syst Biol Med , vol.5 , pp. 367-380
    • Yang, G.1
  • 6
    • 84871980242 scopus 로고    scopus 로고
    • Millisecond spatiotemporal dynamics of FRET biosensors by the pair correlation function and the phasor approach to FLIM
    • Hinde E, Digman MA, Hahn KM, Gratton E: Millisecond spatiotemporal dynamics of FRET biosensors by the pair correlation function and the phasor approach to FLIM. Proc Natl Acad Sci U S A 2013, 110:135-140.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 135-140
    • Hinde, E.1    Digman, M.A.2    Hahn, K.M.3    Gratton, E.4
  • 7
    • 34250856231 scopus 로고    scopus 로고
    • Recombinant anti-CD4 antibody 13B8.2 blocks membrane-proximal events by excluding the Zap70 molecule and downstream targets SLP-76, PLC gamma 1, and Vav-1 from the CD4-segregated Brij 98 detergent-resistant raft domains
    • Chentouf M, Ghannam S, Bés C, Troadec S, Cérutti M, Chardés T: Recombinant anti-CD4 antibody 13B8.2 blocks membrane-proximal events by excluding the Zap70 molecule and downstream targets SLP-76, PLC gamma 1, and Vav-1 from the CD4-segregated Brij 98 detergent-resistant raft domains. J Immunol 2007, 179:409-420.
    • (2007) J Immunol , vol.179 , pp. 409-420
    • Chentouf, M.1    Ghannam, S.2    Bés, C.3    Troadec, S.4    Cérutti, M.5    Chardés, T.6
  • 8
    • 0015310221 scopus 로고
    • Asymmetrical lipid bilayer structure for biological membranes
    • Bretscher MS: Asymmetrical lipid bilayer structure for biological membranes. Nat New Biol 1972, 236:11-12.
    • (1972) Nat New Biol , vol.236 , pp. 11-12
    • Bretscher, M.S.1
  • 9
    • 0015930553 scopus 로고
    • The asymetric arrangement of phospholipids in the human erythrocyte membrane
    • Gordesky SE, Marinetti GV: The asymetric arrangement of phospholipids in the human erythrocyte membrane. Biochem Biophys Res Commun 1973, 50:1027-1031.
    • (1973) Biochem Biophys Res Commun , vol.50 , pp. 1027-1031
    • Gordesky, S.E.1    Marinetti, G.V.2
  • 10
    • 0034331469 scopus 로고    scopus 로고
    • Membrane phospholipid asymmetry and signal transduction
    • Verkleij AJ, Post JA: Membrane phospholipid asymmetry and signal transduction. J Membr Biol 2000, 178:1-10.
    • (2000) J Membr Biol , vol.178 , pp. 1-10
    • Verkleij, A.J.1    Post, J.A.2
  • 12
    • 77952944942 scopus 로고    scopus 로고
    • The distribution and function of phosphatidylserine in cellular membranes
    • Leventis PA, Grinstein S: The distribution and function of phosphatidylserine in cellular membranes. Annu Rev Biophys 2010, 39:407-427.
    • (2010) Annu Rev Biophys , vol.39 , pp. 407-427
    • Leventis, P.A.1    Grinstein, S.2
  • 13
    • 0035082123 scopus 로고    scopus 로고
    • Segregation of gangliosides GM1 and GD3 on cell membranes, isolated membrane rafts, and defined supported lipid monolayers
    • Vyas KA, Patel HV, Vyas AA, Schnaar RL: Segregation of gangliosides GM1 and GD3 on cell membranes, isolated membrane rafts, and defined supported lipid monolayers. Biol Chem 2001, 382:241-250.
    • (2001) Biol Chem , vol.382 , pp. 241-250
    • Vyas, K.A.1    Patel, H.V.2    Vyas, A.A.3    Schnaar, R.L.4
  • 14
    • 0036498797 scopus 로고    scopus 로고
    • Lipid raft heterogeneity in human peripheral blood T lymphoblasts: a mechanism for regulating the initiation of TCR signal transduction
    • Schade AE, Levine AD: Lipid raft heterogeneity in human peripheral blood T lymphoblasts: a mechanism for regulating the initiation of TCR signal transduction. J Immunol 2002, 168:2233-2239.
    • (2002) J Immunol , vol.168 , pp. 2233-2239
    • Schade, A.E.1    Levine, A.D.2
  • 15
    • 0038644451 scopus 로고    scopus 로고
    • Membrane cholesterol regulates LFA-1 function and lipid raft heterogeneity
    • Marwali MR, Rey-Ladino J, Dreolini L, Shaw D, Takei F: Membrane cholesterol regulates LFA-1 function and lipid raft heterogeneity. Blood 2003, 102:215-222.
    • (2003) Blood , vol.102 , pp. 215-222
    • Marwali, M.R.1    Rey-Ladino, J.2    Dreolini, L.3    Shaw, D.4    Takei, F.5
  • 16
    • 1642354334 scopus 로고    scopus 로고
    • Lipid rafts: heterogeneity on the high seas
    • Pike LJ: Lipid rafts: heterogeneity on the high seas. Biochem J 2004, 378:281-292.
    • (2004) Biochem J , vol.378 , pp. 281-292
    • Pike, L.J.1
  • 17
    • 33644764767 scopus 로고    scopus 로고
    • A novel approach to examining compositional heterogeneity of detergent-resistant lipid rafts
    • George S, Nelson MD, Dollahon N, Bamezai A: A novel approach to examining compositional heterogeneity of detergent-resistant lipid rafts. Immunol Cell Biol 2006, 84:192-202.
    • (2006) Immunol Cell Biol , vol.84 , pp. 192-202
    • George, S.1    Nelson, M.D.2    Dollahon, N.3    Bamezai, A.4
  • 18
    • 33845901815 scopus 로고    scopus 로고
    • Lipid rafts: at a crossroad between cell biology and physics
    • Jacobson K, Mouritsen OG, Anderson RG: Lipid rafts: at a crossroad between cell biology and physics. Nat Cell Biol 2007, 9:7-14.
    • (2007) Nat Cell Biol , vol.9 , pp. 7-14
    • Jacobson, K.1    Mouritsen, O.G.2    Anderson, R.G.3
  • 19
    • 48249124978 scopus 로고    scopus 로고
    • Membrane heterogeneities in the formation of B cell receptor-Lyn kinase microclusters and the immune synapse
    • Sohn HW, Tolar P, Pierce SK: Membrane heterogeneities in the formation of B cell receptor-Lyn kinase microclusters and the immune synapse. J Cell Biol 2008, 182:367-379.
    • (2008) J Cell Biol , vol.182 , pp. 367-379
    • Sohn, H.W.1    Tolar, P.2    Pierce, S.K.3
  • 21
    • 74849118341 scopus 로고    scopus 로고
    • Lipid rafts as a membrane-organizing principle
    • Lingwood D, Simons K: Lipid rafts as a membrane-organizing principle. Science 2010, 327:46-50.
    • (2010) Science , vol.327 , pp. 46-50
    • Lingwood, D.1    Simons, K.2
  • 22
    • 0032514258 scopus 로고    scopus 로고
    • Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100 A using imaging fluorescence resonance energy transfer
    • Kenworthy AK, Edidin E: Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100 A using imaging fluorescence resonance energy transfer. J Cell Biol 1998, 142:69-84.
    • (1998) J Cell Biol , vol.142 , pp. 69-84
    • Kenworthy, A.K.1    Edidin, E.2
  • 23
    • 0032421354 scopus 로고    scopus 로고
    • Functions of lipid rafts in biological membranes
    • Brown A, London E: Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 1998, 14:111-136.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 111-136
    • Brown, A.1    London, E.2
  • 24
    • 35649010379 scopus 로고    scopus 로고
    • Lipid rafts, fluid/fluid phase separation, and their relevance to plasma membrane structure and function
    • Sengupta P, Baird B, Holowka D: Lipid rafts, fluid/fluid phase separation, and their relevance to plasma membrane structure and function. Semin Cell Dev Biol 2007, 18:583-590.
    • (2007) Semin Cell Dev Biol , vol.18 , pp. 583-590
    • Sengupta, P.1    Baird, B.2    Holowka, D.3
  • 25
    • 34447292366 scopus 로고    scopus 로고
    • What guides MHC-restricted TCR recognition?
    • Mazza C, Malissen B: What guides MHC-restricted TCR recognition? Semin Immunol 2007, 19:225-235.
    • (2007) Semin Immunol , vol.19 , pp. 225-235
    • Mazza, C.1    Malissen, B.2
  • 28
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks CR, Freiberg BA, Kupfer H, Sciaky N, Kupfer A: Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 1998, 395:82-86.
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 30
    • 0037105477 scopus 로고    scopus 로고
    • Cutting edge: quantitative imaging of raft accumulation in the immunological synapse
    • Burack WR, Lee KH, Holdorf AD, Dustin ML, Shaw AS: Cutting edge: quantitative imaging of raft accumulation in the immunological synapse. J Immunol 2002, 169:2837-2841.
    • (2002) J Immunol , vol.169 , pp. 2837-2841
    • Burack, W.R.1    Lee, K.H.2    Holdorf, A.D.3    Dustin, M.L.4    Shaw, A.S.5
  • 31
    • 0037310832 scopus 로고    scopus 로고
    • MHC class II-peptide complexes and APC lipid rafts accumulate at the immunological synapse
    • Hiltbold EM, Poloso NJ, Roche PA: MHC class II-peptide complexes and APC lipid rafts accumulate at the immunological synapse. J Immunol 2003, 170:1329-1338.
    • (2003) J Immunol , vol.170 , pp. 1329-1338
    • Hiltbold, E.M.1    Poloso, N.J.2    Roche, P.A.3
  • 33
    • 33750533178 scopus 로고    scopus 로고
    • CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse
    • Tavano R, Contento RL, Baranda SJ, Soligo M, Tuosto L, Manes S, Viola A: CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse. Nat Cell Biol 2006, 8:1270-1276.
    • (2006) Nat Cell Biol , vol.8 , pp. 1270-1276
    • Tavano, R.1    Contento, R.L.2    Baranda, S.J.3    Soligo, M.4    Tuosto, L.5    Manes, S.6    Viola, A.7
  • 34
    • 38449100860 scopus 로고    scopus 로고
    • Early and dynamic polarization of T cell membrane rafts and constituents prior to TCR stop signals
    • Van Komen JS, Mishra S, Byrum GR, Chichili JC, Yaciuk A, Farris D, Rodgers W: Early and dynamic polarization of T cell membrane rafts and constituents prior to TCR stop signals. J Immunol 2007, 179:6845-6855.
    • (2007) J Immunol , vol.179 , pp. 6845-6855
    • Komen, J.S.1    Mishra, S.2    Byrum, G.R.3    Chichili, J.C.4    Yaciuk, A.5    Farris, D.6    Rodgers, W.7
  • 35
    • 62049084949 scopus 로고    scopus 로고
    • Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling
    • Zech T, Ejsing CS, Gaus K, de Wet B, Shevchenko A, Simons K, Harder T: Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling. EMBO J 2009, 28:466-476.
    • (2009) EMBO J , vol.28 , pp. 466-476
    • Zech, T.1    Ejsing, C.S.2    Gaus, K.3    Wet, B.4    Shevchenko, A.5    Simons, K.6    Harder, T.7
  • 36
    • 77956277183 scopus 로고    scopus 로고
    • Lipid microdomains and the regulation of ion channel function
    • Dart C: Lipid microdomains and the regulation of ion channel function. J Physiol 2010, 588:3169-3178.
    • (2010) J Physiol , vol.588 , pp. 3169-3178
    • Dart, C.1
  • 37
    • 67349169972 scopus 로고    scopus 로고
    • Lipid rafts/caveolae as microdomains of calcium signaling
    • Pani B, Singh BB: Lipid rafts/caveolae as microdomains of calcium signaling. Cell Calcium 2009, 45:625-633.
    • (2009) Cell Calcium , vol.45 , pp. 625-633
    • Pani, B.1    Singh, B.B.2
  • 38
    • 0142180086 scopus 로고    scopus 로고
    • Store-operated cation entry mediated by CD20 in membrane rafts
    • Li H, Ayer LM, Lytton J, Deans JP: Store-operated cation entry mediated by CD20 in membrane rafts. J Biol Chem 2003, 278:42427-42434.
    • (2003) J Biol Chem , vol.278 , pp. 42427-42434
    • Li, H.1    Ayer, L.M.2    Lytton, J.3    Deans, J.P.4
  • 39
    • 0033998793 scopus 로고    scopus 로고
    • The role of lipid rafts in T cell antigen receptor (TCR) signalling
    • Janes PW, Ley SC, Magee AI, Kabouridis PS: The role of lipid rafts in T cell antigen receptor (TCR) signalling. Semin Immunol 2000, 12:23-34.
    • (2000) Semin Immunol , vol.12 , pp. 23-34
    • Janes, P.W.1    Ley, S.C.2    Magee, A.I.3    Kabouridis, P.S.4
  • 40
    • 0034924486 scopus 로고    scopus 로고
    • The amplification of TCR signaling by dynamic membrane microdomains
    • Viola A: The amplification of TCR signaling by dynamic membrane microdomains. Trends Immunol 2001, 22:322-327.
    • (2001) Trends Immunol , vol.22 , pp. 322-327
    • Viola, A.1
  • 41
    • 77956220615 scopus 로고    scopus 로고
    • Cholesterol induces specific spatial and orientational order in cholesterol/phospholipid membranes
    • Martinez-Seara H, RÓg T, Karttunen M, Vattulainen I, Reigada R: Cholesterol induces specific spatial and orientational order in cholesterol/phospholipid membranes. PLoS One 2010, 5:e11162.
    • (2010) PLoS One , vol.5
    • Martinez-Seara, H.1    RÓg, T.2    Karttunen, M.3    Vattulainen, I.4    Reigada, R.5
  • 42
    • 84869428183 scopus 로고    scopus 로고
    • + T cell line: interaction with antigen presenting cells promotes coalescing of lipid rafts
    • + T cell line: interaction with antigen presenting cells promotes coalescing of lipid rafts. Cell Commun Signal 2011, 9:e31.
    • (2011) Cell Commun Signal , vol.9 , pp. e31
    • Kennedy, C.1    Nelson, M.D.2    Bamezai, A.K.3
  • 43
    • 0032101348 scopus 로고    scopus 로고
    • Membrane compartmentation is required for efficient T cell activation
    • Xavier R, Brennan T, Li Q, McCormack C, Seed B: Membrane compartmentation is required for efficient T cell activation. Immunity 1998, 8:723-732.
    • (1998) Immunity , vol.8 , pp. 723-732
    • Xavier, R.1    Brennan, T.2    Li, Q.3    McCormack, C.4    Seed, B.5
  • 45
    • 0344585437 scopus 로고    scopus 로고
    • Lipid rafts: elusive or illusive?
    • Munro S: Lipid rafts: elusive or illusive? Cell 2003, 115:377-388.
    • (2003) Cell , vol.115 , pp. 377-388
    • Munro, S.1
  • 46
    • 33750130964 scopus 로고    scopus 로고
    • Lipid rafts: now you see them, now you don't
    • Shaw AS: Lipid rafts: now you see them, now you don't. Nat Immunol 2006, 7:1139-1142.
    • (2006) Nat Immunol , vol.7 , pp. 1139-1142
    • Shaw, A.S.1
  • 47
    • 43049102669 scopus 로고    scopus 로고
    • Cholesterol homeostasis in T cells. Methyl-beta-cyclodextrin treatment results in equal loss of cholesterol from Triton X-100 soluble and insoluble fractions
    • Mahammad S, Parmryd I: Cholesterol homeostasis in T cells. Methyl-beta-cyclodextrin treatment results in equal loss of cholesterol from Triton X-100 soluble and insoluble fractions. Biochim Biophys Acta 2008, 1778:1251-1258.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 1251-1258
    • Mahammad, S.1    Parmryd, I.2
  • 49
    • 54249149865 scopus 로고    scopus 로고
    • Interferon-γ enhances clonal expansion and survival of CD4+ T cells
    • Reed J, Branigan P, Bamezai A: Interferon-γ enhances clonal expansion and survival of CD4 + T cells. J Interferon Cytokine Res 2008, 28:611-622.
    • (2008) J Interferon Cytokine Res , vol.28 , pp. 611-622
    • Reed, J.1    Branigan, P.2    Bamezai, A.3
  • 52
    • 79953190405 scopus 로고    scopus 로고
    • Primary human CD4+ T cells have diverse levels of membrane lipid order that correlate with their function
    • Miguel L, Owen DM, Lim C, Liebig C, Evans J, Magee MI, Jury EC: Primary human CD4+ T cells have diverse levels of membrane lipid order that correlate with their function. J Immunol 2011, 186:3505-3516.
    • (2011) J Immunol , vol.186 , pp. 3505-3516
    • Miguel, L.1    Owen, D.M.2    Lim, C.3    Liebig, C.4    Evans, J.5    Magee, M.I.6    Jury, E.C.7
  • 53
    • 0031750335 scopus 로고    scopus 로고
    • Lipid domain structure of the plasma membrane revealed by patching of membrane components
    • Harder T, Scheiffele P, Verkade P, Simons K: Lipid domain structure of the plasma membrane revealed by patching of membrane components. J Cell Biol 1998, 141:929-942.
    • (1998) J Cell Biol , vol.141 , pp. 929-942
    • Harder, T.1    Scheiffele, P.2    Verkade, P.3    Simons, K.4
  • 54
    • 23244453354 scopus 로고    scopus 로고
    • Cholesterol enriched lipid domains can be visualized by di4ANEPPDHQ with linear and nonlinear optics
    • Jin L, Millard AC, Wuskell JP, Clark HA, Loew LM: Cholesterol enriched lipid domains can be visualized by di4ANEPPDHQ with linear and nonlinear optics. Biophys J 2005, 89:L04-6.
    • (2005) Biophys J , vol.89 , pp. L04-6
    • Jin, L.1    Millard, A.C.2    Wuskell, J.P.3    Clark, H.A.4    Loew, L.M.5
  • 55
    • 29144484142 scopus 로고    scopus 로고
    • Partitioning of membrane molecules between raft and non-raft domains: insights from model-membrane studies
    • Silvius JR: Partitioning of membrane molecules between raft and non-raft domains: insights from model-membrane studies. Biochim Biophys Acta 2005, 1746:193-202.
    • (2005) Biochim Biophys Acta , vol.1746 , pp. 193-202
    • Silvius, J.R.1
  • 56
    • 23044515913 scopus 로고    scopus 로고
    • The polar nature of 7-ketocholesterol determines its location within membrane domains and the kinetics of membrane microsolubilization by apolipoprotein A-I
    • Massey JB, Pownall HJ: The polar nature of 7-ketocholesterol determines its location within membrane domains and the kinetics of membrane microsolubilization by apolipoprotein A-I. Biochemistry 2005, 44:10423-10433.
    • (2005) Biochemistry , vol.44 , pp. 10423-10433
    • Massey, J.B.1    Pownall, H.J.2
  • 57
    • 77954217091 scopus 로고    scopus 로고
    • Interaction of two oxysterols, 7-ketocholesterol and 25-hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes
    • Mintzer E, Charles G, Gordon S: Interaction of two oxysterols, 7-ketocholesterol and 25-hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes. Chem Phys Lipids 2010, 163:586-593.
    • (2010) Chem Phys Lipids , vol.163 , pp. 586-593
    • Mintzer, E.1    Charles, G.2    Gordon, S.3
  • 58
    • 67650179212 scopus 로고    scopus 로고
    • 7-ketocholesterol incorporation into sphingolipid/cholesterol-enriched (lipid raft) domains is impaired by vitamin E: a specific role for alpha-tocopherol with consequences on cell death
    • Royer MC, Lemaire-Ewing S, Desrumaux C, Monier S, Pais de Barros JP, Athias A, Néel D, Lagrost L: 7-ketocholesterol incorporation into sphingolipid/cholesterol-enriched (lipid raft) domains is impaired by vitamin E: a specific role for alpha-tocopherol with consequences on cell death. J Biol Chem 2009, 284:15826-15834.
    • (2009) J Biol Chem , vol.284 , pp. 15826-15834
    • Royer, M.C.1    Lemaire-Ewing, S.2    Desrumaux, C.3    Monier, S.4    Pais de Barros, J.P.5    Athias, A.6    Néel, D.7    Lagrost, L.8
  • 59
    • 57349145336 scopus 로고    scopus 로고
    • Spatiotemporal analysis of differential Akt regulation in plasma membrane microdomains
    • Gao X, Zhang J: Spatiotemporal analysis of differential Akt regulation in plasma membrane microdomains. Mol Biol Cell 2008, 19:4366-4373.
    • (2008) Mol Biol Cell , vol.19 , pp. 4366-4373
    • Gao, X.1    Zhang, J.2
  • 60
    • 67349170030 scopus 로고    scopus 로고
    • Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol
    • Liu J, Netherland C, Pickle T, Sinensky MS, Thewke DP: Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol. Arch Biochem Biophys 2009, 487:54-58.
    • (2009) Arch Biochem Biophys , vol.487 , pp. 54-58
    • Liu, J.1    Netherland, C.2    Pickle, T.3    Sinensky, M.S.4    Thewke, D.P.5
  • 61
    • 0037464468 scopus 로고    scopus 로고
    • AKT1/PKBalpha is recruited to lipid rafts and activated downstream of PKC isotypes in CD3-induced T cell signaling
    • Bauer B, Jenny M, Fresser F, Uberall F, Baier G: AKT1/PKBalpha is recruited to lipid rafts and activated downstream of PKC isotypes in CD3-induced T cell signaling. FEBS Lett 2003, 541:155-162.
    • (2003) FEBS Lett , vol.541 , pp. 155-162
    • Bauer, B.1    Jenny, M.2    Fresser, F.3    Uberall, F.4    Baier, G.5
  • 63
    • 12344270987 scopus 로고    scopus 로고
    • What's so special about cholesterol?
    • Mouritsen OG, Zuckermann MJ: What's so special about cholesterol? Lipids 2004, 39:1101-1113.
    • (2004) Lipids , vol.39 , pp. 1101-1113
    • Mouritsen, O.G.1    Zuckermann, M.J.2
  • 65
    • 77954660372 scopus 로고    scopus 로고
    • Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity
    • Aye IL, Waddell BJ, Mark PJ, Keelan JA: Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity. Biochim Biophys Acta 2010, 1801:1013-1024.
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 1013-1024
    • Aye, I.L.1    Waddell, B.J.2    Mark, P.J.3    Keelan, J.A.4


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