메뉴 건너뛰기




Volumn 13, Issue 2, 2015, Pages 319-329

TGFβ1 protects cells from γ-IR by enhancing the activity of the NHEJ repair pathway

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEIC ACID LIGASE 4; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; DNA LIGASE; DNA LIGASE (ATP); SMAD PROTEIN; TGFB1 PROTEIN, HUMAN;

EID: 84923879744     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-14-0098-T     Document Type: Article
Times cited : (41)

References (29)
  • 1
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y,Massague J.Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003;113:685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 2
    • 0030978315 scopus 로고    scopus 로고
    • Repression of the CDK activator Cdc25A and cellcycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15
    • Iavarone A, Massague J. Repression of the CDK activator Cdc25A and cellcycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15. Nature 1997;387:417-22.
    • (1997) Nature , vol.387 , pp. 417-422
    • Iavarone, A.1    Massague, J.2
  • 3
    • 0028603343 scopus 로고
    • TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
    • Miettinen PJ, Ebner R, Lopez AR, Derynck R. TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. J Cell Biol 1994;127:2021-36.
    • (1994) J Cell Biol , vol.127 , pp. 2021-2036
    • Miettinen, P.J.1    Ebner, R.2    Lopez, A.R.3    Derynck, R.4
  • 4
    • 80455144497 scopus 로고    scopus 로고
    • TGFbeta1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo
    • Bouquet F, Pal A, Pilones KA, Demaria S, Hann B, Akhurst RJ, et al. TGFbeta1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo. Clin Cancer Res 2011;17:6754-65.
    • (2011) Clin Cancer Res , vol.17 , pp. 6754-6765
    • Bouquet, F.1    Pal, A.2    Pilones, K.A.3    Demaria, S.4    Hann, B.5    Akhurst, R.J.6
  • 5
    • 82655181475 scopus 로고    scopus 로고
    • Blockade of TGF-beta signaling by the TGFbetaR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma
    • Zhang M, Kleber S, Rohrich M, Timke C, Han N, Tuettenberg J, et al. Blockade of TGF-beta signaling by the TGFbetaR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma. Cancer Res 2011;71:7155-67.
    • (2011) Cancer Res , vol.71 , pp. 7155-7167
    • Zhang, M.1    Kleber, S.2    Rohrich, M.3    Timke, C.4    Han, N.5    Tuettenberg, J.6
  • 6
    • 33845303212 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress
    • Kirshner J, Jobling MF, Pajares MJ, Ravani SA, Glick AB, Lavin MJ, et al. Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress. Cancer Res 2006;66:10861-9.
    • (2006) Cancer Res , vol.66 , pp. 10861-10869
    • Kirshner, J.1    Jobling, M.F.2    Pajares, M.J.3    Ravani, S.A.4    Glick, A.B.5    Lavin, M.J.6
  • 7
    • 59849089955 scopus 로고    scopus 로고
    • Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
    • Mahaney BL, Meek K, Lees-Miller SP. Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem J 2009;417:639-50.
    • (2009) Biochem J , vol.417 , pp. 639-650
    • Mahaney, B.L.1    Meek, K.2    Lees-Miller, S.P.3
  • 8
    • 41149094512 scopus 로고    scopus 로고
    • Regulation of DNA repair throughout the cell cycle
    • Branzei D, Foiani M. Regulation of DNA repair throughout the cell cycle. Nat Rev Mol Cell Biol 2008;9:297-308.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 297-308
    • Branzei, D.1    Foiani, M.2
  • 9
    • 0036668842 scopus 로고    scopus 로고
    • TGFbeta1 -mediated epithelial to mesenchymal transition is accompanied by invasion in the SiHa cell line
    • Yi JY, Hur KC, Lee E, Jin YJ, Arteaga CL, Son YS. TGFbeta1 -mediated epithelial to mesenchymal transition is accompanied by invasion in the SiHa cell line. Eur J Cell Biol 2002;81:457-68.
    • (2002) Eur J Cell Biol , vol.81 , pp. 457-468
    • Yi, J.Y.1    Hur, K.C.2    Lee, E.3    Jin, Y.J.4    Arteaga, C.L.5    Son, Y.S.6
  • 11
    • 32944459979 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining
    • Wang HC, Chou WC, Shieh SY, Shen CY. Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining. Cancer Res 2006;66:1391-400.
    • (2006) Cancer Res , vol.66 , pp. 1391-1400
    • Wang, H.C.1    Chou, W.C.2    Shieh, S.Y.3    Shen, C.Y.4
  • 12
    • 14844292557 scopus 로고    scopus 로고
    • DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks
    • Drouet J, Delteil C, Lefrancois J, Concannon P, Salles B, Calsou P. DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks. J Biol Chem 2005;280:7060-9.
    • (2005) J Biol Chem , vol.280 , pp. 7060-7069
    • Drouet, J.1    Delteil, C.2    Lefrancois, J.3    Concannon, P.4    Salles, B.5    Calsou, P.6
  • 15
    • 0028898203 scopus 로고
    • Potential role of WAF1/Cip1/p21 as amediator of TGF-beta cytoinhibitory effect
    • Li CY, Suardet L, Little JB. Potential role of WAF1/Cip1/p21 as amediator of TGF-beta cytoinhibitory effect. J Biol Chem 1995;270:4971-4.
    • (1995) J Biol Chem , vol.270 , pp. 4971-4974
    • Li, C.Y.1    Suardet, L.2    Little, J.B.3
  • 16
    • 55449119244 scopus 로고    scopus 로고
    • p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation
    • Soria G, Speroni J, Podhajcer OL, Prives C, Gottifredi V. p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation. J Cell Sci 2008;121:3271-82.
    • (2008) J Cell Sci , vol.121 , pp. 3271-3282
    • Soria, G.1    Speroni, J.2    Podhajcer, O.L.3    Prives, C.4    Gottifredi, V.5
  • 17
    • 0036467496 scopus 로고    scopus 로고
    • TGF-beta signaling: Positive and negative effects on tumorigenesis
    • Wakefield LM, Roberts AB. TGF-beta signaling: positive and negative effects on tumorigenesis. Curr Opin Genet Dev 2002;12:22-9.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 22-29
    • Wakefield, L.M.1    Roberts, A.B.2
  • 18
    • 42049107059 scopus 로고    scopus 로고
    • TGF-beta signaling promotes survival and repair in rat alveolar epithelial type 2 cells during recovery after hyperoxic injury
    • Buckley S, Shi W, Barsky L, Warburton D. TGF-beta signaling promotes survival and repair in rat alveolar epithelial type 2 cells during recovery after hyperoxic injury. Am J Physiol Lung Cell Mol Physiol 2008;294:L739-48.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294 , pp. L739-L748
    • Buckley, S.1    Shi, W.2    Barsky, L.3    Warburton, D.4
  • 19
    • 84875548281 scopus 로고    scopus 로고
    • TGF-beta signaling plays an important role in resisting gamma-irradiation
    • An YS, Kim MR, Lee SS, Lee YS, Chung E, Song JY, et al. TGF-beta signaling plays an important role in resisting gamma-irradiation. Exp Cell Res 2013;319:466-73.
    • (2013) Exp Cell Res , vol.319 , pp. 466-473
    • An, Y.S.1    Kim, M.R.2    Lee, S.S.3    Lee, Y.S.4    Chung, E.5    Song, J.Y.6
  • 20
    • 84865140762 scopus 로고    scopus 로고
    • Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-beta
    • Hardee ME, Marciscano AE, Medina-Ramirez CM, Zagzag D, Narayana A, Lonning SM, et al. Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-beta. Cancer Res 2012;72:4119-29.
    • (2012) Cancer Res , vol.72 , pp. 4119-4129
    • Hardee, M.E.1    Marciscano, A.E.2    Medina-Ramirez, C.M.3    Zagzag, D.4    Narayana, A.5    Lonning, S.M.6
  • 21
    • 0034649208 scopus 로고    scopus 로고
    • Mechanism of ultraviolet B-induced cell cycle arrest in G2/M phase in immortalized skin keratinocytes with defective p53
    • Athar M, Kim AL, Ahmad N, Mukhtar H, Gautier J, Bickers DR. Mechanism of ultraviolet B-induced cell cycle arrest in G2/M phase in immortalized skin keratinocytes with defective p53. Biochem Biophys Res Commun 2000;277:107-11.
    • (2000) Biochem Biophys Res Commun , vol.277 , pp. 107-111
    • Athar, M.1    Kim, A.L.2    Ahmad, N.3    Mukhtar, H.4    Gautier, J.5    Bickers, D.R.6
  • 22
    • 0033953099 scopus 로고    scopus 로고
    • UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G(2) checkpoint abrogation
    • Sugiyama K, Shimizu M, Akiyama T, Tamaoki T, Yamaguchi K, Takahashi R, et al. UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G(2) checkpoint abrogation. Int J Cancer 2000;85:703-9.
    • (2000) Int J Cancer , vol.85 , pp. 703-709
    • Sugiyama, K.1    Shimizu, M.2    Akiyama, T.3    Tamaoki, T.4    Yamaguchi, K.5    Takahashi, R.6
  • 23
    • 0029784067 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 suppresses genomic instability independent of a G1 arrest, p53, and Rb
    • Glick AB, Weinberg WC, Wu IH, Quan W, Yuspa SH. Transforming growth factor beta 1 suppresses genomic instability independent of a G1 arrest, p53, and Rb. Cancer Res 1996;56:3645-50.
    • (1996) Cancer Res , vol.56 , pp. 3645-3650
    • Glick, A.B.1    Weinberg, W.C.2    Wu, I.H.3    Quan, W.4    Yuspa, S.H.5
  • 24
    • 0036500132 scopus 로고    scopus 로고
    • Functional proteomics of transforming growth factor-beta1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFbeta1-dependent regulation of DNA repair
    • Kanamoto T, Hellman U, Heldin CH, Souchelnytskyi S. Functional proteomics of transforming growth factor-beta1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFbeta1-dependent regulation of DNA repair. EMBO J 2002;21:1219-30.
    • (2002) EMBO J , vol.21 , pp. 1219-1230
    • Kanamoto, T.1    Hellman, U.2    Heldin, C.H.3    Souchelnytskyi, S.4
  • 25
    • 84857415007 scopus 로고    scopus 로고
    • Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses
    • Chiba N, Comaills V, Shiotani B, Takahashi F, Shimada T, Tajima K, et al. Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses. Proc Natl Acad Sci U S A 2012;109:2760-5.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 2760-2765
    • Chiba, N.1    Comaills, V.2    Shiotani, B.3    Takahashi, F.4    Shimada, T.5    Tajima, K.6
  • 26
    • 0029004150 scopus 로고
    • DNA repair defect tied to mutated TGF-beta receptor gene
    • Marx J. DNA repair defect tied to mutated TGF-beta receptor gene. Science 1995;268:1276-7.
    • (1995) Science , vol.268 , pp. 1276-1277
    • Marx, J.1
  • 27
    • 77953166592 scopus 로고    scopus 로고
    • GammaH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization
    • Lobrich M, Shibata A, Beucher A, Fisher A, Ensminger M, Goodarzi AA, et al. gammaH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization. Cell Cycle 2010;9:662-9.
    • (2010) Cell Cycle , vol.9 , pp. 662-669
    • Lobrich, M.1    Shibata, A.2    Beucher, A.3    Fisher, A.4    Ensminger, M.5    Goodarzi, A.A.6
  • 29
    • 68349095151 scopus 로고    scopus 로고
    • Human DNA damage response and repair deficiency syndromes: Linking genomic instability and cell cycle checkpoint proficiency
    • Kerzendorfer C, O'Driscoll M. Human DNA damage response and repair deficiency syndromes: linking genomic instability and cell cycle checkpoint proficiency. DNA Repair 2009;8:1139-52.
    • (2009) DNA Repair , vol.8 , pp. 1139-1152
    • Kerzendorfer, C.1    O'Driscoll, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.