A Tail of Two Sites: A Bipartite Mechanism for Recognition of Notch Ligands by Mind Bomb E3 Ligases

Molecular Cell

Volumn 57, Issue 5, 2015, Pages 912-924

  McMillan, Brian J ^a   Schnute, Björn ^b   Ohlenhard, Nadja ^b   Zimmerman, Brandon ^a,c   Miles, Laura ^a,c   Beglova, Natalia ^a,d   Klein, Thomas ^b   Blacklow, Stephen C ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA HELICASE; DROSOPHILA PROTEIN; EPITOPE; HERC2 PROTEIN; JAGGED1; MIND BOMB 1 PROTEIN; MIND BOMB PROTEIN; NOTCH RECEPTOR; PROTEIN SH3; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CALCIUM BINDING PROTEIN; LIGAND; MEMBRANE PROTEIN; MIB1 LIGASE, HUMAN; MIND BOMB PROTEIN, DROSOPHILA; PROTEIN BINDING; SERRATE PROTEINS; SIGNAL PEPTIDE; UBIQUITIN PROTEIN LIGASE; WG PROTEIN, DROSOPHILA; WNT1 PROTEIN;

ARTICLE; BIOCHEMISTRY; CARBOXY TERMINAL SEQUENCE; CELL ASSAY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOPLASM; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRACELLULAR MEMBRANE; LIGAND BINDING; MOLECULAR RECOGNITION; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; UBIQUITINATION; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DROSOPHILA MELANOGASTER; GENETICS; HEK293 CELL LINE; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; TUMOR CELL LINE; WESTERN BLOTTING; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CALCIUM-BINDING PROTEINS; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EPITOPES; HEK293 CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NOTCH; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITIN-PROTEIN LIGASES; WNT1 PROTEIN;

EID: 84923879189     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.01.019     Document Type: Article

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