Cysteine modified and bile salt based micelles: Preparation and application as an oral delivery system for paclitaxel

Colloids and Surfaces B: Biointerfaces

Volumn 128, Issue , 2015, Pages 165-171

  Xu, Wei ^a   Fan, Xiaohui ^b   Zhao, Yanli ^b   Li, Lingbing ^b  

^a THE FIRST AFFILIATED HOSPITAL OF SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Cysteine modified; Micelles; Oral; Paclitaxel; Sodium cholate

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CRITICAL MICELLE CONCENTRATION; DRUG DELIVERY; HYDROGELS;

CYSTEINE MODIFIED; ORAL; ORAL DRUG DELIVERY SYSTEM; PACLITAXEL; PHARMACOKINETIC STUDIES; PHYSICOCHEMICAL PROPERTY; POLYION COMPLEX MICELLES; SODIUM CHOLATE;

MICELLES;

BILE SALT; CHITOSAN; CHOLIC ACID; CYSTEINE; PACLITAXEL; POLOXAMER; ANTINEOPLASTIC AGENT; DRUG CARRIER; MICELLE; SURFACTANT;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG RELEASE; DRUG STABILITY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MICELLE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; STOMACH JUICE; TIME TO MAXIMUM PLASMA CONCENTRATION; ZETA POTENTIAL; ANIMAL; BIOAVAILABILITY; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; HUMAN; MCF 7 CELL LINE; ORAL DRUG ADMINISTRATION; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CELL SURVIVAL; CHITOSAN; CYSTEINE; DRUG CARRIERS; DRUG STABILITY; HUMANS; MALE; MCF-7 CELLS; MICELLES; PACLITAXEL; POLOXAMER; RATS; RATS, WISTAR; SODIUM CHOLATE; SURFACE-ACTIVE AGENTS;

EID: 84923878620     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2015.02.031     Document Type: Article

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