High-fat diet induces endothelial dysfunction through a down-regulation of the endothelial AMPK-PI3K-Akt-eNOS pathway

Molecular Nutrition and Food Research

Volumn 59, Issue 3, 2015, Pages 520-532

  García Prieto, Concha F ^a   Hernández Nuño, Francisco ^a   Rio, Danila Del ^a   Ruiz Hurtado, Gema ^b,c   Aránguez, Isabel ^b   Ruiz Gayo, Mariano ^a   Somoza, Beatriz ^a   Fernández Alfonso, María S ^b  

^a UNIVERSIDAD SAN PABLO CEU   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

Adenosine monophosphate activated protein kinase; Endothelial function; High fat diet; Obesity prone; Obesity resistant

Indexed keywords

RATTUS;

ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; NOS3 PROTEIN, RAT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; STK11 PROTEIN, RAT; SUPEROXIDE DISMUTASE;

ADVERSE EFFECTS; ANIMAL; BODY WEIGHT; DOWN REGULATION; DRUG EFFECTS; ENDOTHELIUM CELL; LIPID DIET; MALE; METABOLISM; MITOCHONDRION; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BODY WEIGHT; DIET, HIGH-FAT; DOWN-REGULATION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; MALE; MITOCHONDRIA; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE;

EID: 84923842271     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201400539     Document Type: Article

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