Does apical membrane GLUT2 have a role in intestinal glucose uptake?

F1000Research

Volumn 3, Issue , 2014, Pages

  Naftalin, Richard J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHALASIN B; GLUCOSE; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 5; MESSENGER RNA; PHLORETIN; PHLORIZIN; SODIUM; SODIUM GLUCOSE COTRANSPORTER 1;

APICAL MEMBRANE; CAPILLARY PERMEABILITY; COMPUTER MODEL; GENE EXPRESSION REGULATION; GLUCOSE ABSORPTION; GLUCOSE TRANSPORT; GLUT2 GENE; INTERSTITIAL FLUID; INTESTINE ABSORPTION; INTESTINE BRUSH BORDER MEMBRANE; INTESTINE CELL; OSMOREGULATION; PROTEIN EXPRESSION; REVIEW; SODIUM TRANSPORT; WATER FLOW; WATER TRANSPORT;

EID: 84923673913     PISSN: 20461402     EISSN: 1759796X     Source Type: Journal    
DOI: 10.12688/f1000research.5934.1     Document Type: Review

References (53)

1. Kellett GL Helliwell PA: The diffusive component of intestinal glucose absorption is mediated by the glucose-induced recruitment of GLUT2 to the brush-border membrane. Biochem J. 2000;350(Pt 1):155-62. 10926839 10.1042/0264-6021:3500155 1221237
2. Hummel CS Lu C Loo DD: Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2. Am J Physiol Cell Physiol. 2011;300(1):C14-21. 20980548 10.1152/ajpcell.00388.2010 3023189
3. Hummel CS Lu C Liu J: Structural selectivity of human SGLT inhibitors. Am J Physiol Cell Physiol. 2012;302(2):C373-82. 21940664 10.1152/ajpcell.00328.2011 3328840
4. Debnam ES Levin RJ: Effects of fasting and semistarvation on the kinetics of active and passive sugar absorption across the small intestine in vivo. J Physiol. 1975;252(3):681-700. 1206572 1348490
5. IIundain A Lluch M Pons F: Kinetics of intestinal sugar transport, in vivo. Rev Esp Fisiol. 1979;35(3):359-66. 504779
6. Bolufer J Delgado MJ Murillo F: Galactose transport across rat small intestine in vivo following distal resections of varying extents. Q J Exp Physiol. 1986;71(3):423-31. 3763805
7. Pappenheimer JR Reiss KZ: Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat. J Membr Biol. 1987;100(2):123-36. 3430569 10.1007/BF02209145
8. Pappenheimer JR: Paracellular intestinal absorption of glucose, creatinine, and mannitol in normal animals: relation to body size. Am J Physiol. 1990;259(2 Pt 1):G290-9. 2116731
9. Naftalin RJ Tripathi S: The roles of paracellular and transcellular pathways and submucosal space in isotonic water absorption by rabbit ileum. J Physiol. 1986;370:409-32. 3958981 1192688
10. Fischbarg J: Fluid transport across leaky pithelia: central role of the tight junction and supporting role of aquaporins. Physiol Rev. 2010;90(4):1271-90. 20959616 10.1152/physrev.00025.2009
11. Pappenheimer JR Michel CC: Role of villus microcirculation in intestinal absorption of glucose: coupling of epithelial with endothelial transport. J Physiol. 2003;553(Pt 2):561-74. 12937296 10.1113/jphysiol.2003.043257 2343570
12. Granger DN Mortillaro NA Taylor AE: Interactions of intestinal lymph flow and secretion. Am J Physiol. 1977;232(1):E13-8. 835698
13. Bijlsma PB Fihn BM Sjöqvist A: Water absorption enhances the uptake of mannitol and decreases Cr-EDTA/mannitol permeability ratios in cat small intestine in situ. Scand J Gastroenterol. 2002;37(7):799-806. 12190093 10.1080/gas.37.7.799.806
14. Boyd CA Cheeseman CI Parsons DS: Effects of sodium on solute transport between compartments in intestinal mucosal epithelium. Nature. 1975;256(5520):747-9. 1153016 10.1038/256747a0
15. Boyd CA Parsons DS: Movements of monosaccharides between blood and tissues of vascularly perfused small intestine. J Physiol. 1979;287:371-91. 430421 1281501
16. Kellett GL Brot-Laroche E: Apical GLUT2: a major pathway of intestinal sugar absorption. Diabetes. 2005;54:3056-62. 16186415 10.2337/diabetes.54.10.3056
17. Kellett GL Brot-Laroche E Mace OJ: Sugar absorption in the intestine: the role of GLUT2. Annu Rev Nutr. 2008;28:35-54. 18393659 10.1146/annurev.nutr.28.061807.155518
18. Mace OJ Affleck J Patel N: Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2. J Physiol. 2007;582(Pt 1):379-92. 17495045 10.1113/jphysiol.2007.130906 2075289
19. Mace OJ Schindler M Patel S: The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine. J Physiol. 2012;590(Pt 12):2917-36. 22495587 10.1113/jphysiol.2011.223800 3448156
20. Stumpel F Burcelin R Jungermann K: Normal kinetics of intestinal glucose absorption in the absence of GLUT2: evidence for a transport pathway requiring glucose phosphorylation and transfer into the endoplasmic reticulum. Proc Natl Acad Sci U S A. 2001;98(20):11330-5. 11562503 10.1073/pnas.211357698 58729
21. Arbuckle MI Kane S Porter LM: Structure-function analysis of liver-type (GLUT2) and brain-type (GLUT3) glucose transporters: expression of chimeric transporters in Xenopus oocytes suggests an important role for putative transmembrane helix 7 in determining substrate selectivity. Biochemistry. 1996;35(51):16519-27. 8987985 10.1021/bi962210n
22. Hoffmann EK Simonsen LO Sjoholm C: Membrane potential, chloride exchange and chloride conductance in Ehrlich mouse ascites tumour cells. J Physiol. 1979;296:61-84. 529133 1279064
23. Esteva-Font C Phuan PW Anderson MO: A small molecule screen identifies selective inhibitors of urea transporter UT-A. Chem Biol. 2013;20(10):1235-44. 24055006 10.1016/j.chembiol.2013.08.005 3890325
24. Röder PV Geillinger KE Zietek TS: The role of SGLT1 and GLUT2 in intestinal glucose transport and sensing. PLoS One. 2014;9(2):e89977. 24587162 10.1371/journal.pone.0089977 3935955
25. Shirazi-Beechey SP Moran AW Batchelor DJ: Glucose sensing and signalling; regulation of intestinal glucose transport. Proc Nutr Soc. 2012;70(2):185-93. 21450125 10.1017/S0029665111000103
26. Ma J Chang J Checklin HL: Effect of the artificial sweetener, sucralose, on small intestinal glucose absorption in healthy human subjects. Br J Nutr. 2010;104(6):803-6. 20420761 10.1017/S0007114510001327
27. Ford HE Peters V Martin NM: Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects. Eur J Clin Nutr. 2011;65(4):508-13. 21245879 10.1038/ejcn.2010.291
28. Kellett GL: Comment on: Gorboulev et al. Na+-D-glucose cotransporter SGLT1 Is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes 2012;61:187-196. Diabetes. 2012:61(6):e4. 22618779 10.2337/db11-1793 3357282
29. Habold C Foltzer-Jourdainne C Le Maho Y: Intestinal gluconeogenesis and glucose transport according to body fuel availability in rats. J Physiol. 2005;566(Pt 2):575-86. 15878950 10.1113/jphysiol.2005.085217 1464758
30. Brot-Laroche E Dao MT Alcaldet AI: Independent modulation by food supply of two distinct sodium-activated D-glucose transport systems in the guinea pig jejunal brush-border membrane. Proc Natl Acad Sci U S A. 1988;85(17):6370-3. 3413102 10.1073/pnas.85.17.6370 281973
31. Brot-Laroche E Supplisson S Delhomme B: Characterization of the D-glucose/Na+ cotransport system in the intestinal brush-border membrane by using the specific substrate, methyl alpha-D-glucopyranoside. Biochim Biophys Acta. 1987;904(1):71-80. 3663668 10.1016/0005-2736(87)90088-5
32. Cohen M Kitsberg D Tsytkin S: Live imaging of GLUT2 glucose-dependent trafficking and its inhibition in polarized epithelial cysts. Open Biol. 2014;4(7). 25056286 10.1098/rsob.140091 4118605
33. Karasov WH Debnam ES: Rapid adaptation of intestinal glucose transport: a brush-border or basolateral phenomenon? Am J Physiol. 1987;253(1 Pt 1):G54-61. 3605337
34. Cheeseman CI O'Neill D: Basolateral D-glucose transport activity along the crypt-villus axis in rat jejunum and upregulation induced by gastric inhibitory peptide and glucagon-like peptide-2. Exp Physiol. 1998;83(5):605-16. 9793781
35. Holman GD Naftalin RJ: Transport of 3-O-methyl D-glucose and beta-methyl D-glucoside by rabbit ileum. Biochim Biophys Acta. 1976;433(3):597-614. 1276193 10.1016/0005-2736(76)90284-4
36. Eskandari S Wright EM Loo DD: Kinetics of the reverse mode of the Na+/glucose cotransporter. J Membr Biol. 2005;204(1):23-32. 16007500 10.1007/s00232-005-0743-x 3000923
37. Kedem O Katchalsky A: Permeability of composite membranes. Part 3.-Series array of elements. Trans Faraday Soc. 1963;59:1941-53. 10.1039/TF9635901941
38. Bohlen HG: Intestinal tissue PO 2 and microvascular responses during glucose exposure. Am J Physiol. 1980;238(2):H164-71. 7361909
39. Bohlen HG: Na +-induced intestinal interstitial hyperosmolality and vascular responses during absorptive hyperemia. Am J Physiol. 1982;242(5):H785-9. 7081449
40. Vanis L Gentilcore D Rayner CK: Effects of small intestinal glucose load on blood pressure, splanchnic blood flow, glycemia, and GLP-1 release in healthy older subjects. Am J Physiol Regul Integr Comp Physiol. 2011;300(6):R1524-31. 21389332 10.1152/ajpregu.00378.2010
41. Qamar MI Read AE Mountford R: Increased superior mesenteric artery blood flow after glucose but not lactulose ingestion. Q J Med. 1986;60(233):893-6. 3628705
42. Someya N Endo MY Fukuba Y: Blood flow responses in celiac and superior mesenteric arteries in the initial phase of digestion. Am J Physiol Regul Integr Comp Physiol. 2008;294(6):R1790-6. 18385466 10.1152/ajpregu.00553.2007
43. Granger DN Kvietys PR Mailman D: Intrinsic regulation of functional blood flow and water absorption in canine colon. J Physiol. 1980;307:443-51. 7205673 1283055
44. Moran AW Al-Rammahi MA Arora DK: Expression of Na+/glucose co-transporter 1 (SGLT1) in the intestine of piglets weaned to different concentrations of dietary carbohydrate. Br J Nutr. 2010;104(5):647-55. 20385036 10.1017/S0007114510000954
45. Nguyen NQ Debreceni TL Bambrick JE: Accelerated intestinal glucose absorption in morbidly obese humans - relationship to glucose transporters, incretin hormones and glycaemia. J Clin Endocrinol Metab. 2014:jc20143144. 25423571 10.1210/jc.2014-3144
46. Anzueto Hernandez L Kvietys PR Granger DN: Postprandial hemodynamics in the conscious rat. Am J Physiol. 1986;251(1 Pt 1):G117-23. 3728670
47. Granger DN Kvietys PR Wilborn WH: Mechanism of glucagon-induced intestinal secretion. Am J Physiol. 1980;239(1):G30-8. 7396000
48. Parker HE Adriaenssens A Rogers G: Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion. Diabetologia. 2012;55(9):2445-55. 22638549 10.1007/s00125-012-2585-2 3411305
49. Macleod RJ Hamilton JR: Volume regulation initiated by Na(+)-nutrient cotransport in isolated mammalian villus enterocytes. Am J Physiol. 1991;260(1 Pt 1):G26-33. 1702936
50. Zeuthen T: Water-transporting proteins. J Membr Biol. 2010;234(2):57-73. 20091162 10.1007/s00232-009-9216-y
51. Naftalin RJ: Osmotic water transport with glucose in GLUT2 and SGLT. Biophys J. 2008;94(10):3912-23. 18234816 10.1529/biophysj.107.122531 2367205
52. Granger DN: Intestinal microcirculation and transmucosal fluid transport. Am J Physiol. 1981;240(5):G343-9. 7015880
53. Naftalin RJ: Reassessment of models of facilitated transport and cotransport. J Membr Biol. 2010;234(2):75-112. 20204338 10.1007/s00232-010-9228-7