Effect of aged bone marrow microenvironment on mesenchymal stem cell migration

Age

Volumn 37, Issue 2, 2015, Pages

  Yang, Yan Mei ^a,b   Li, Ping ^a,b   Cui, Dian Chao ^c   Dang, Rui Jie ^a,b   Zhang, Lei ^b   Wen, Ning ^a   Jiang, Xiao Xia ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^c Beijing Aiyuhua Hospital for Children and Women   (China)

Author keywords

Aged; Bone marrow microenvironment; Mesenchymal stem cells; Migration

Indexed keywords

CD11B ANTIGEN; CD3 ANTIGEN; CD45 ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CD3+ T LYMPHOCYTE; CELL AGING; CELL CULTURE; CELL MIGRATION; CELL MOTION; CELL PROLIFERATION; CELL SELECTION; COCULTURE; COLONY FORMATION; CONTROLLED STUDY; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; IMMUNOPHENOTYPING; MESENCHYMAL STEM CELL; MICROENVIRONMENT; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; AGING; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CELL MIGRATION ASSAY; CYTOLOGY; FEMALE; MALE; MESENCHYMAL STROMA CELL; PHOSPHORYLATION; PHYSIOLOGY; STEM CELL NICHE;

AGING; ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL MIGRATION ASSAYS; CELL MOVEMENT; COCULTURE TECHNIQUES; FEMALE; FLOW CYTOMETRY; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MESENCHYMAL STROMAL CELLS; MICE, INBRED C57BL; PHOSPHORYLATION; STEM CELL NICHE;

EID: 84923666981     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-014-9743-z     Document Type: Article

References (30)

1. Askari AT, Unzek S, Popovic ZB, Goldman CK, Forudi F, Kiedrowski M, Rovner A, Ellis SG, Thomas JD, DiCorleto PE, Topol EJ, Penn MS (2003) Effect of stromal cell derived factor-1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy. Lancet 362:697–703
2. Bruder SP, Jaiswal N, Haynesworth SE (1997) Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation. J Cell Biol Chem 64:278–294
3. Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, Martin RP, Schipani E, Divieti P, Bringhurst FR, Milner LA, Kronenberg HM, Scadden DT (2003) Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425:841–846
4. Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, Choop M (2001) Therapeutic benefit of intravenousadministration of bone marrow stromal cells after cerebral ischemia in rats. Stroke 32:1005–1011
5. Chen FM, Wu LA, Zhang M, Zhang R, Sun HH (2011) Homing of endogenous stem/progenitor cells for in situ tissue regeneration: promises, strategies, and translational perspectives. Biomaterials 32:3189–3209
6. Chen LZ, Yin SM, Zhang XL, Chen JY, Wei BX, Zhan Y, Yu W, Wu JM, Qu J, Guo ZK (2012) Protective effects of human bone marrow mesenchymalstemcells on hematopoietic organs of irradiated mice. Zhongguo Shi Yan Xue Ye Xue Za Zhi 20:1436–1441
7. Chishti MA, Kaya N, Binbakheet AB, Al-Mohanna F, Goyns MH, Colak D (2013) Induction of cell proliferation in old rat liver can reset certain gene expression levels characteristic of old liver to those associated with young liver. Age (Dordr) 35:719–732
8. D’Agostino B, Sullo N, Siniscalco D, De Angelis A, Rossi F (2010) Mesenchymal stem cell therapy for the treatment of chronic obstructive pulmonary disease. Expert Opin Biol Ther 10:681–687
9. Dazzi F, Ramasamy R, Glennie S, Jones SP, Roberts I (2006) The role of mesenchymal stem cells in haemopoiesis. Blood Rev 20:161–171
10. de Haan G, Nijhof W, Van Zant G (1997) Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity. Blood 89:1543–1550
11. Devine SM, Bartholomew AM, Mahmud N, Nelson M, Patil S, Hardy W, Sturgeon C, Hewett T, Chung T, Stock W, Sher D, Weissman S, Ferrer K, Mosca J, Deans R, Moseley A, Hoffman R (2001) Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusion. Exp Hematol 29:244–255
12. Donnini A, Re F, Orlando F, Provinciali M (2007) Intrinsic and microenvironmental defects are involved in the age-related changes of Lin-ckit + hematopoietic progenitor cells. Rejuvenation Res 10:459–472
13. Gao H, Priebe W, Glod J, Banerjee D (2009) Activation of signal transducers and activators of transcription 3 and focal adhesion kinase by stromal cell-derived factor 1 is required for migration of human mesenchymal stem cells in response to tumor cellconditioned medium. Stem Cells 27:857–865
14. Li F, Jin F, Freitas A, Szabo P, Weksler ME (2001) Impaired regeneration of the peripheral B cell repertoire from bone marrow following lymphopenia in old mice. Eur J Immunol 31:500–505
15. Li ZY, Wang CQ, Lu G (2011) Effects of bone marrow mesenchymal stem cells on hematopoietic recovery and acute graft-versus-host disease in murine allogeneic umbilical cord blood transplantation model. Zhonghua Xue Ye Xue Za Zhi 32:786–789
16. Loebinger MR, Eddaoudi A, Davies D, Janes SM (2009) Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer. Cancer Res 69:4134–4142
17. Mazzini L, Ferrero I, Luparello V, Rustichelli D, Gunetti M, Mareschi K, Testa L, Stecco A, Tarletti R, Miglioretti M, Fava E, Nasuelli N, Cisari C, Massara M, Vercelli R, Oggioni GD, Carriero A, Cantello R, Monaco F, Fagioli F (2010) Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: a Phase I clinical trial. Exp Neurol 223:229–237
18. Min H, Montecino-Rodriguez E, Dorshkind K (2006) Effects of aging on the common lymphoid progenitor to pro-Bcell transition. J Immunol 176:1007–1012
19. Morrison SJ, Wandycz AM, Akashi K, Globerson A, Weissman IL (1996) The aging of hematopoietic stem cells. Nat Med 2:1011–1016
20. Muslin AJ (2008) MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets. Clin Sci (Lond) 115:203–218
21. Prockop DJ (1997) Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276:71–74
22. Shao HW, Xu QY, Wu QL, Ma Q, Salqueiro L, Wang J, Eton D, Webster KA, Yu H (2011) Defective CXCR4 expression in aged bone marrow cells impairs vascular regeneration. J Cell Mol Med 15:2046–2056
23. Sudo K, Ema H, Morita Y, Nakauchi H (2000) Age-associated characteristics of murine hematopoietic stem cells. J Exp Med 192:1273–1280
24. Veronesi F, Pagani S, Della Bella E, Giavaresi G, Fini M (2014) Estrogen deficiency does not decrease the in vitro osteogenic potential of rat adipose-derived mesenchymal stem cells. Age 36:1225–1238
25. Wang MC, Bohmann D, Jasper H (2005) JNK extends life span and limits growth by antagonizing cellular and organism wide responses to insulin signaling. Cell 121:115–125
26. Waterstrat A, Van Zant G (2009) Effects of aging on hematopoietic stem and progenitor cells. Curr Opin Immunol 21:408–413
27. Yang YM, Li H, Zhang L, Dang RJ, Li P, Wang XY, Zhu H, Guo XM, Zhang Y, Liu YL, Mao N, Jiang XX, Wen N (2013) A new method for isolating and culturing mouse bone marrow mesenchymal stem cells. Zhongguo Shi Yan Xue Ye Xue Za Zhi 21:1563–1567
28. Yuan L, Sakamoto N, Song G, Sato M (2013) Low-level shear stress induces human mesenchymal stem cell migration through the SDF-1/CXCR4 axis via MAPK signaling pathways. Stem Cell Dev 22:2384–2393
29. Zediak VP, Maillard I, Bhandoola A (2007) Multiple prethymic defects underlie age-related loss of T progenitor competence. Blood 110:1161–1167
30. Zhu X, Gui J, Dohkan J, Cheng L, Barnes PF, Su DM (2007) Lymphohematopoietic progenitors do not have a synchronized defect with age-related thymic involution. Aging Cell 6:663–672