메뉴 건너뛰기




Volumn 36, Issue 3, 2014, Pages 1225-1238

Estrogen deficiency does not decrease the in vitro osteogenic potential of rat adipose-derived mesenchymal stem cells

Author keywords

Adipose stem cells; Adult stem cells; Cell biology; Cell culture; Gene expression; Osteoporosis

Indexed keywords

5' NUCLEOTIDASE; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; CD31 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; COLLAGEN; ENDOGLIN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HERMES ANTIGEN; INTERLEUKIN 1BETA; LIPOPROTEIN LIPASE; OSTEOCALCIN; OSTEOPONTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; THY 1 ANTIGEN; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN A;

EID: 84905407647     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-014-9647-y     Document Type: Article
Times cited : (11)

References (38)
  • 1
    • 84857856822 scopus 로고    scopus 로고
    • Human stromal (mesenchymal) stem cells: Basic biology and current clinical use for tissue regeneration
    • Aldahmash A, Zaher W, Al-Nbaheen M, Kassem M (2012) Human stromal (mesenchymal) stem cells: basic biology and current clinical use for tissue regeneration. Ann Saudi Med 32:68-77
    • (2012) Ann Saudi Med , vol.32 , pp. 68-77
    • Aldahmash, A.1    Zaher, W.2    Al-Nbaheen, M.3    Kassem, M.4
  • 3
    • 24344455975 scopus 로고    scopus 로고
    • Estrogen receptor alpha binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor gamma signaling in breast cancer cells
    • DOI 10.1158/1078-0432.CCR-04-2453
    • Bonofiglio D, Gabriele S, Aquila S, Catalano S, Gentile M, Middea E, Giordano F, Antò S (2005) Estrogen receptor alpha binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor gamma signaling in breast cancer cells. Clin Cancer Res 11:6139-6147 (Pubitemid 41262940)
    • (2005) Clinical Cancer Research , vol.11 , Issue.17 , pp. 6139-6147
    • Bonofiglio, D.1    Gabriele, S.2    Aquila, S.3    Catalano, S.4    Gentile, M.5    Middea, E.6    Giordano, F.7    Ando, S.8
  • 4
    • 84869863662 scopus 로고    scopus 로고
    • The osteoclast, bone remodelling and treatment of metabolic bone disease
    • doi:10.1111/j.1365-2362.2012.02717.x
    • Boyce BF, Rosenberg E, de Papp AE, le Duong T (2012) The osteoclast, bone remodelling and treatment of metabolic bone disease. Eur J Clin Invest 42:1332-1341. doi:10.1111/j.1365-2362.2012.02717.x
    • (2012) Eur J Clin Invest , vol.42 , pp. 1332-1341
    • Boyce, B.F.1    Rosenberg, E.2    De Papp, A.E.3    Le Duong, T.4
  • 5
    • 58249138164 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy on connective tissue: Why is this important?
    • doi:10.1016/j.bpobgyn.2008.10.003
    • Calleja-Agius J, Brincat MP (2009) Effects of hormone replacement therapy on connective tissue: why is this important? Best Pract Res Clin Obstet Gynaecol 23:121-127. doi:10.1016/j.bpobgyn.2008.10.003
    • (2009) Best Pract Res Clin Obstet Gynaecol , vol.23 , pp. 121-127
    • Calleja-Agius, J.1    Brincat, M.P.2
  • 6
    • 84863136375 scopus 로고    scopus 로고
    • Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures
    • doi:10.1111/j.1582-4934.2011.01335.x
    • Chen HT, Lee MJ, Chen CH, Chuang SC, Chang LF, Ho ML, Hung SH, Fu YC, Wang YH, Wang HI, Wang GJ, Kang L, Chang JK (2012) Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures. J Cell Mol Med 16:582-592. doi:10.1111/j.1582-4934.2011.01335.x
    • (2012) J Cell Mol Med , vol.16 , pp. 582-592
    • Chen, H.T.1    Lee, M.J.2    Chen, C.H.3    Chuang, S.C.4    Chang, L.F.5    Ho, M.L.6    Hung, S.H.7    Fu, Y.C.8    Wang, Y.H.9    Wang, H.I.10    Wang, G.J.11    Kang, L.12    Chang, J.K.13
  • 7
    • 84891918848 scopus 로고    scopus 로고
    • Effects of remifemin treatment on bone integrity and remodeling in rats with ovariectomy-induced osteoporosis
    • doi:10.1371/journal.pone.0082815
    • Cui G, Leng H, Wang K, Wang J, Zhu S, Jia J, Chen X, Zhang W, Qin L, Bai W (2013) Effects of remifemin treatment on bone integrity and remodeling in rats with ovariectomy-induced osteoporosis. PLoS One 8:e82815. doi:10.1371/journal. pone.0082815
    • (2013) PLoS One , vol.8
    • Cui, G.1    Leng, H.2    Wang, K.3    Wang, J.4    Zhu, S.5    Jia, J.6    Chen, X.7    Zhang, W.8    Qin, L.9    Bai, W.10
  • 8
    • 70350550255 scopus 로고    scopus 로고
    • Circulating mesenchymal stem cells with abnormal osteogenic differentiation in patients with osteoporosis
    • doi:10.1002/art.24884
    • Dalle Carbonare L, Valenti MT, Zanatta M, Donatelli L, Lo Cascio V (2009) Circulating mesenchymal stem cells with abnormal osteogenic differentiation in patients with osteoporosis. Arthritis Rheum 60:3356-3365. doi:10.1002/art.24884
    • (2009) Arthritis Rheum , vol.60 , pp. 3356-3365
    • Dalle Carbonare, L.1    Valenti, M.T.2    Zanatta, M.3    Donatelli, L.4    Lo Cascio, V.5
  • 9
    • 73649114552 scopus 로고    scopus 로고
    • Human adipose-derived stem cells isolated from young and elderly women: Their differentiation potential and scaffold interaction during in vitro osteoblastic differentiation
    • doi:10.3109/14653240903079393
    • de Girolamo L, Lopa S, Arrigoni E, Sartori MF, Baruffaldi Preis FW, Brini AT (2009) Human adipose-derived stem cells isolated from young and elderly women: their differentiation potential and scaffold interaction during in vitro osteoblastic differentiation. Cytotherapy 11:793-803. doi:10.3109/ 14653240903079393
    • (2009) Cytotherapy , vol.11 , pp. 793-803
    • De Girolamo, L.1    Lopa, S.2    Arrigoni, E.3    Sartori, M.F.4    Baruffaldi Preis, F.W.5    Brini, A.T.6
  • 10
    • 84875013035 scopus 로고    scopus 로고
    • MicroRNA regulation of adipose derived stem cells in aging rats
    • doi:10.1371/journal.pone.0059238
    • Fei J, Tamski H, Cook C, Santanam N (2013) MicroRNA regulation of adipose derived stem cells in aging rats. Plos One 8:1-11. doi:10.1371/journal.pone. 0059238
    • (2013) Plos One , vol.8 , pp. 1-11
    • Fei, J.1    Tamski, H.2    Cook, C.3    Santanam, N.4
  • 11
    • 33646103658 scopus 로고    scopus 로고
    • Fat tissue: An underappreciated source of stem cells for biotechnology
    • Fraser JK, Wulur I, Alfonso Z, Hedrick MH (2006) Fat tissue: an underappreciated source of stem cells for biotechnology. Trends Biotechnol 24:150-154
    • (2006) Trends Biotechnol , vol.24 , pp. 150-154
    • Fraser, J.K.1    Wulur, I.2    Alfonso, Z.3    Hedrick, M.H.4
  • 12
    • 83255194168 scopus 로고    scopus 로고
    • In vivo preclinical evaluation of the influence of osteoporosis on the anchorage of different pedicle screw designs
    • doi:10.1007/s00586-011-1831-5
    • Giavaresi G, Fini M, Giardino R, Salamanna F, Sartori M, Borsari V, Spriano S, Bellini CM, Brayda-Bruno M (2011) In vivo preclinical evaluation of the influence of osteoporosis on the anchorage of different pedicle screw designs. Eur Spine J 20:1289-1296. doi:10.1007/s00586-011-1831-5
    • (2011) Eur Spine J , vol.20 , pp. 1289-1296
    • Giavaresi, G.1    Fini, M.2    Giardino, R.3    Salamanna, F.4    Sartori, M.5    Borsari, V.6    Spriano, S.7    Bellini, C.M.8    Brayda-Bruno, M.9
  • 13
    • 84863863767 scopus 로고    scopus 로고
    • The relationship between adipose tissue and bone metabolism
    • doi:10.1016/j.clinbiochem.2012.03.006
    • Gimble JM, Nuttall ME (2012) The relationship between adipose tissue and bone metabolism. Clin Biochem 45:874-879. doi:10.1016/j.clinbiochem.2012.03.006
    • (2012) Clin Biochem , vol.45 , pp. 874-879
    • Gimble, J.M.1    Nuttall, M.E.2
  • 14
    • 84860008632 scopus 로고    scopus 로고
    • Differentiation-dependent secretion of proangiogenic factors by mesenchymal stem cells
    • doi:10.1371/journal.pone.0035579
    • Hoch AI, Binder BY, Genetos DC, Leach JK (2012) Differentiation-dependent secretion of proangiogenic factors by mesenchymal stem cells. PLoS One 7:e35579. doi:10.1371/journal.pone.0035579
    • (2012) PLoS One , vol.7
    • Hoch, A.I.1    Binder, B.Y.2    Genetos, D.C.3    Leach, J.K.4
  • 15
    • 57249084243 scopus 로고    scopus 로고
    • Adipose stem cells for intervertebral disc regeneration: Current status and concepts for the future
    • doi:10.1111/j.1582-4934.2008.00291.x
    • Hoogendoorn RJ, Lu ZF, Kroeze RJ, Bank RA, Wuisman PI, Helder MN (2008) Adipose stem cells for intervertebral disc regeneration: current status and concepts for the future. J Cell Mol Med 12:2205-2216. doi:10.1111/j.1582-4934. 2008.00291.x
    • (2008) J Cell Mol Med , vol.12 , pp. 2205-2216
    • Hoogendoorn, R.J.1    Lu, Z.F.2    Kroeze, R.J.3    Bank, R.A.4    Wuisman, P.I.5    Helder, M.N.6
  • 16
    • 84855719657 scopus 로고    scopus 로고
    • The balance of osteogenic and adipogenic differentiation in human mesenchymal stem cells by matrices that mimic stepwise tissue development
    • doi:10.1016/j.biomaterials.2011.11.061
    • Hoshiba T, Kawazoe N, Chen G (2012) The balance of osteogenic and adipogenic differentiation in human mesenchymal stem cells by matrices that mimic stepwise tissue development. Biomaterials 33:2015-2031. doi:10.1016/j.biomaterials.2011.11.061
    • (2012) Biomaterials , vol.33 , pp. 2015-2031
    • Hoshiba, T.1    Kawazoe, N.2    Chen, G.3
  • 17
    • 61549139769 scopus 로고    scopus 로고
    • The epitope characterization and the osteogenic differentiation potential of human fat pad-derived stem cells is maintained with ageing in later life
    • doi:10.1016/j.injury.2008.05.029
    • Khan WS, Adesida AB, Tew SR, Andrew JG, Hardingham TE (2009) The epitope characterization and the osteogenic differentiation potential of human fat pad-derived stem cells is maintained with ageing in later life. Injury 40:150-157. doi:10.1016/j.injury.2008.05.029
    • (2009) Injury , vol.40 , pp. 150-157
    • Khan, W.S.1    Adesida, A.B.2    Tew, S.R.3    Andrew, J.G.4    Hardingham, T.E.5
  • 18
    • 79952117327 scopus 로고    scopus 로고
    • Morphologic and transcriptomic comparison of adipose- and bone-marrow-derived porcine stem cells cultured in alginate hydrogels
    • doi:10.1007/s00441-010-1015-3
    • Kim D, Monaco E, Maki A, de Lima AS, Kong HJ, Hurley WL, Wheeler MB (2010) Morphologic and transcriptomic comparison of adipose- and bone-marrow-derived porcine stem cells cultured in alginate hydrogels. Cell Tissue Res 341:359-370. doi:10.1007/s00441-010-1015-3
    • (2010) Cell Tissue Res , vol.341 , pp. 359-370
    • Kim, D.1    Monaco, E.2    Maki, A.3    De Lima, A.S.4    Kong, H.J.5    Hurley, W.L.6    Wheeler, M.B.7
  • 19
    • 84864991731 scopus 로고    scopus 로고
    • The role of nacreous factors in preventing osteoporotic bone loss through both osteoblast activation and osteoclast inactivation
    • doi:10.1016/j.biomaterials.2012.06.098
    • Kim H, Lee K, Ko CY, Kim HS, Shin HI, Kim T, Lee SH, Jeong D (2012) The role of nacreous factors in preventing osteoporotic bone loss through both osteoblast activation and osteoclast inactivation. Biomaterials 33:7489-7496. doi:10.1016/j.biomaterials.2012.06.098
    • (2012) Biomaterials , vol.33 , pp. 7489-7496
    • Kim, H.1    Lee, K.2    Ko, C.Y.3    Kim, H.S.4    Shin, H.I.5    Kim, T.6    Lee, S.H.7    Jeong, D.8
  • 20
    • 76749168867 scopus 로고    scopus 로고
    • The effect of hydrofluoric acid treatment on titanium implant osseointegration in ovariectomized rats
    • doi:10.1016/j.biomaterials.2010.01.028
    • Li Y, Zou S, Wang D, Feng G, Bao C, Hu J (2010) The effect of hydrofluoric acid treatment on titanium implant osseointegration in ovariectomized rats. Biomaterials 31:3266-3273. doi:10.1016/j.biomaterials.2010. 01.028
    • (2010) Biomaterials , vol.31 , pp. 3266-3273
    • Li, Y.1    Zou, S.2    Wang, D.3    Feng, G.4    Bao, C.5    Hu, J.6
  • 21
    • 0035710746 scopus 로고    scopus 로고
    • -DeltaDeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 22
    • 84859941981 scopus 로고    scopus 로고
    • Telomere length, telomerase activity and osteogenic differentiation are maintained in adipose-derived stromal cells from senile osteoporotic SAMP6 mice
    • doi:10.1002/term.440
    • Mirsaidi A, Kleinhans KN, Rimann M, Tiaden AN, Stauber M, Rudolph KL, Richards PJ (2012) Telomere length, telomerase activity and osteogenic differentiation are maintained in adipose-derived stromal cells from senile osteoporotic SAMP6 mice. J Tissue Eng Regen Med 6:378-390. doi:10.1002/term.440
    • (2012) J Tissue Eng Regen Med , vol.6 , pp. 378-390
    • Mirsaidi, A.1    Kleinhans, K.N.2    Rimann, M.3    Tiaden, A.N.4    Stauber, M.5    Rudolph, K.L.6    Richards, P.J.7
  • 23
    • 84857638323 scopus 로고    scopus 로고
    • Influence of age and body mass index on the yield and proliferation capacity of adipose-derived stem cells
    • doi:10.1007/s00266-011-9743-7
    • Mojallal A, Lequeux C, Shipkov C, Duclos A, Braye F, Rohrich R, Brown S, Damour O (2011) Influence of age and body mass index on the yield and proliferation capacity of adipose-derived stem cells. Aesthetic Plast Surg 35:1097-1105. doi:10.1007/s00266-011-9743-7
    • (2011) Aesthetic Plast Surg , vol.35 , pp. 1097-1105
    • Mojallal, A.1    Lequeux, C.2    Shipkov, C.3    Duclos, A.4    Braye, F.5    Rohrich, R.6    Brown, S.7    Damour, O.8
  • 25
    • 78650667231 scopus 로고    scopus 로고
    • Stromal stem cells from adipose tissue and bone marrow of age-matched female donors display distinct immunophenotypic profiles
    • doi:10.1002/jcp.22408
    • Pachon-Pena G, Yu G, Tucker A, Wu X, Vendrell J, Bunnell BA, Gimble JM (2010) Stromal stem cells from adipose tissue and bone marrow of age-matched female donors display distinct immunophenotypic profiles. J Cell Physiol 226:843-851. doi:10.1002/jcp.22408
    • (2010) J Cell Physiol , vol.226 , pp. 843-851
    • Pachon-Pena, G.1    Yu, G.2    Tucker, A.3    Wu, X.4    Vendrell, J.5    Bunnell, B.A.6    Gimble, J.M.7
  • 26
    • 84871494098 scopus 로고    scopus 로고
    • In osteoporosis, differentiation of mesenchymal stem cells (MSCs) improves bone marrow adipogenesis
    • doi:10.4067/S0716-97602012000300009
    • Pino AM, Rosen CJ, Rodriguez JP (2012) In osteoporosis, differentiation of mesenchymal stem cells (MSCs) improves bone marrow adipogenesis. Biol Res 45:279-287. doi:10.4067/S0716-97602012000300009
    • (2012) Biol Res , vol.45 , pp. 279-287
    • Pino, A.M.1    Rosen, C.J.2    Rodriguez, J.P.3
  • 28
    • 52749090092 scopus 로고    scopus 로고
    • Involvement of adipogenic potential of human bone marrow mesenchymal stem cells (MSCs) in osteoporosis
    • Rodriguez JP, Astudillo P, Rios S, Pino AM (2008) Involvement of adipogenic potential of human bone marrow mesenchymal stem cells (MSCs) in osteoporosis. Curr Stem Cell Res Ther 3:208-218
    • (2008) Curr Stem Cell Res Ther , vol.3 , pp. 208-218
    • Rodriguez, J.P.1    Astudillo, P.2    Rios, S.3    Pino, A.M.4
  • 29
    • 16644400131 scopus 로고    scopus 로고
    • Differential activation of ERK1,2 MAP kinase signaling pathway in mesenchymal stem cell from control and osteoporotic postmenopausal women
    • DOI 10.1002/jcb.20119
    • Rodriguez JP, Rios S, Fernandez M, Santibanez F (2004) Differential activation of ERK1,2 MAP kinase signaling pathway in mesenchymal stem cells from control and osteoporotic postmenopausal women. J Cell Biochem 92:745-754 (Pubitemid 44264265)
    • (2004) Journal of Cellular Biochemistry , vol.92 , Issue.4 , pp. 745-754
    • Rodriguez, J.P.1    Rios, S.2    Fernandez, M.3    Santibanez, J.F.4
  • 30
    • 23344443288 scopus 로고    scopus 로고
    • The osteogenic potential of adipose-derived mesenchmal cells is maintained with aging
    • DOI 10.1097/01.prs.0000185606.03222.a9
    • Shi YY, Nacamuli RP, Salim A, Longaker MT (2005) The osteogenic potential of adipose-derived mesenchymal stem cells is maintained with aging. Plast Reconstruct Surg 116:1686-1696 (Pubitemid 41608338)
    • (2005) Plastic and Reconstructive Surgery , vol.116 , Issue.6 , pp. 1686-1696
    • Shi, Y.-Y.1    Nacamuli, R.P.2    Salim, A.3    Longaker, M.T.4
  • 31
    • 84887139083 scopus 로고    scopus 로고
    • A comparative study of the bone metabolic response to dried plum supplementation and PTH treatment in adult, osteopenic ovariectomized rat
    • doi:10.1016/j.bone.2013.10.005
    • Smith BJ, Bu SY, Wang Y, Rendina E, Lim YF, Marlow D, Clarke SL, Cullen DM, Lucas EA (2014) A comparative study of the bone metabolic response to dried plum supplementation and PTH treatment in adult, osteopenic ovariectomized rat. Bone 58:151-159. doi:10.1016/j.bone.2013.10.005
    • (2014) Bone , vol.58 , pp. 151-159
    • Smith, B.J.1    Bu, S.Y.2    Wang, Y.3    Rendina, E.4    Lim, Y.F.5    Marlow, D.6    Clarke, S.L.7    Cullen, D.M.8    Lucas, E.A.9
  • 32
    • 79959917318 scopus 로고    scopus 로고
    • Adipose-derived stem cells: Current findings and future perspectives
    • Tobita M, Orbay H, Mizuno H (2011) Adipose-derived stem cells: current findings and future perspectives. Discov Med 11:160-170
    • (2011) Discov Med , vol.11 , pp. 160-170
    • Tobita, M.1    Orbay, H.2    Mizuno, H.3
  • 33
    • 84892510443 scopus 로고    scopus 로고
    • In vitro tenocyte metabolism in aging and oestrogen deficiency
    • doi:10.1007/s11357-012-9500-0
    • Torricelli P, Veronesi F, Pagani S, Maffulli N, Masiero S, Frizziero A, Fini M (2012) In vitro tenocyte metabolism in aging and oestrogen deficiency. Age 35:2125-2136. doi:10.1007/s11357-012-9500-0
    • (2012) Age , vol.35 , pp. 2125-2136
    • Torricelli, P.1    Veronesi, F.2    Pagani, S.3    Maffulli, N.4    Masiero, S.5    Frizziero, A.6    Fini, M.7
  • 34
    • 79958046094 scopus 로고    scopus 로고
    • Role of Ox-PPACs in the differentiation of mesenchymal stem cells (MSCs) and Runx2 and PPARγ2 expression in MSCs-like of osteoporotic patients
    • doi:10.1371/journal.pone.0020363
    • Valenti MT, Garbin U, Pasini A, Zanatta M, Stranieri C, Manfro S, Zucal C, Dalle Carbonare L (2011) Role of Ox-PPACs in the differentiation of mesenchymal stem cells (MSCs) and Runx2 and PPARγ2 expression in MSCs-like of osteoporotic patients. Plos One 6:e20363. doi:10.1371/journal.pone.0020363
    • (2011) Plos One , vol.6
    • Valenti, M.T.1    Garbin, U.2    Pasini, A.3    Zanatta, M.4    Stranieri, C.5    Manfro, S.6    Zucal, C.7    Dalle Carbonare, L.8
  • 36
    • 78650257620 scopus 로고    scopus 로고
    • PPARγ in bone homeostasis
    • doi:10.1016/j.tem.2010.08.006
    • Wan Y (2010) PPARγ in bone homeostasis. Trends Endocrinol Metab 21:722-728. doi:10.1016/j.tem.2010.08.006
    • (2010) Trends Endocrinol Metab , vol.21 , pp. 722-728
    • Wan, Y.1
  • 37
    • 84872068303 scopus 로고    scopus 로고
    • The effect of age on human adipose-derived stem cells
    • doi:10.1097/PRS.0b013e3182729cfc
    • Wu W, Niklason L, Steinbacher DM (2013) The effect of age on human adipose-derived stem cells. Plast Reconstr Surg 131:27-37. doi:10.1097/PRS. 0b013e3182729cfc
    • (2013) Plast Reconstr Surg , vol.131 , pp. 27-37
    • Wu, W.1    Niklason, L.2    Steinbacher, D.M.3
  • 38
    • 67349107689 scopus 로고    scopus 로고
    • The effect of age on osteogenic, adipogenic and proliferative potential of female adipose-derived stem cells
    • doi:10.1002/term.165
    • Zhu M, Kohan E, Bradley J, Hedrick M, Benhaim P, Zuk P (2009) The effect of age on osteogenic, adipogenic and proliferative potential of female adipose-derived stem cells. J Tissue Eng Reg Med 3:290-301. doi:10.1002/term.165
    • (2009) J Tissue Eng Reg Med , vol.3 , pp. 290-301
    • Zhu, M.1    Kohan, E.2    Bradley, J.3    Hedrick, M.4    Benhaim, P.5    Zuk, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.