Synthesis and assessment of the antioxidant and antitumor properties of asymmetric curcumin analogues

European Journal of Medicinal Chemistry

Volumn 93, Issue , 2015, Pages 461-469

  Li, Qingyong ^a,b   Chen, Jian ^a,b   Luo, Shuyue ^a,b   Xu, Jialin ^a,b   Huang, Qiaoxian ^a,b   Liu, Tianyu ^a,b  

^a ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^b NORTHEAST FORESTRY UNIVERSITY   (China)

Author keywords

Anti proliferate; Antioxidant; Asymmetric curcumin analogues

Indexed keywords

1 (2 HYDROXY 4 METHOXYPHENYL) 5 (3,4,5 TRIMETHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (3 ETHOXY 4 HYDROXYPHENYL) 5 (4 HYDROXY 3 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (3 HYDROXY 4 METHOXYPHENYL) 5 (3,4,5 TRIMETHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (3 HYDROXY 4 METHOXYPHENYL) 5 (4 HYDROXY 3 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (3,4 DIMETHOXYPHENYL) 5 (2 HYDROXY 4 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (3,4 DIMETHOXYPHENYL) 5 (4 HYDROXY 3 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (3,4 DIMETHOXYPHENYL) 5 (4 HYDROXY 3,5 DIMETHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (3,4 DIMETHYLPHENYL) 5 (2 HYDROXY 4 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (3,4 DIMETHYLPHENYL) 5 (4 HYDROXY 3 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (3,4 DIMETHYLPHENYL) 5 (4 HYDROXY 3,5 DIMETHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (3,4,5 TRIMETHOXYPHENYL) 5 (4 HYDROXY 3,5 DIMETHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1 (4 HYDROXY 3,5 DIMETHOXYPHENYL) 5 (4 HYDROXY 3 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1,5 BIS (3 ETHOXY 4 HYDROXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1,5 BIS (3 HYDROXY 4 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1,5 BIS (3,4 DIMETHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1,5 BIS (3,4,5 TRIMETHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; 1,5 BIS (4 HYDROXY 3 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; CARBON; CURCUMIN; FREE RADICAL; HYDROGEN; OXYGEN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; SCAVENGER;

ABTS RADICAL SCAVENGING ASSAY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; COVALENT BOND; CYTOTOXICITY; DISSOCIATION; DPPH RADICAL SCAVENGING ASSAY; DRUG SYNTHESIS; ELECTRON TRANSPORT; ENTHALPY; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; IC50; MALE; MCF 7 CELL LINE; PROSTATE CANCER CELL LINE; REACTION ANALYSIS; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; ANALOGS AND DERIVATIVES; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMISTRY TECHNIQUES, SYNTHETIC; CURCUMIN; FREE RADICAL SCAVENGERS; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84923565527     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2015.02.005     Document Type: Article

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