메뉴 건너뛰기




Volumn 22, Issue 1, 2015, Pages R33-R49

Models of neuroendocrine prostate cancer

Author keywords

Cancer; Castration resistant prostate; Genetically engineered mice; Neuroendocrine prostate; Xenograft tumors

Indexed keywords

ANIMAL MODEL; CANCER GROWTH; CANCER HORMONE THERAPY; CANCER MODEL; CARCINOGENESIS; CLINICAL FEATURE; DRUG TREATMENT FAILURE; GENETIC MANIPULATION; GENETICALLY ENGINEERED MOUSE STRAIN; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MOUSE; NEUROENDOCRINE TUMOR; NONHUMAN; PROSTATE ADENOCARCINOMA; PROSTATE CANCER; PROSTATIC ACINAR ADENOCARCINOMA; REVIEW; SMALL CELL CARCINOMA; SMALL CELL NEUROENDOCRINE CARCINOMA; TUMOR XENOGRAFT; ANIMAL; CARCINOMA; DISEASE MODEL; GENETICS; HUMAN; MALE; METABOLISM; PATHOLOGY; PROSTATE TUMOR; XENOGRAFT;

EID: 84923560698     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1530/ERC-14-0393     Document Type: Review
Times cited : (47)

References (69)
  • 1
    • 41849140534 scopus 로고    scopus 로고
    • Irradiation enhances the metastatic potential of prostatic small cell carcinoma xenografts
    • Agemy L, Harmelin A, Waks T, Leibovitch I, Rabin T, Pfeffer MR & Eshhar Z 2008 Irradiation enhances the metastatic potential of prostatic small cell carcinoma xenografts. Prostate 68 530-539. (doi:10.1002/pros. 20702)
    • (2008) Prostate , vol.68 , pp. 530-539
    • Agemy, L.1    Harmelin, A.2    Waks, T.3    Leibovitch, I.4    Rabin, T.5    Pfeffer, M.R.6    Eshhar, Z.7
  • 2
    • 27944459717 scopus 로고    scopus 로고
    • SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation
    • Ahuja D, Saenz-Robles MT & Pipas JM 2005 SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation. Oncogene 24 7729-7745. (doi:10.1038/sj.onc.1209046)
    • (2005) Oncogene , vol.24 , pp. 7729-7745
    • Ahuja, D.1    Saenz-Robles, M.T.2    Pipas, J.M.3
  • 3
    • 0035100475 scopus 로고    scopus 로고
    • Cellular transformation by SV40 large T antigen: Interaction with host proteins
    • Ali SH & DeCaprio JA 2001 Cellular transformation by SV40 large T antigen: interaction with host proteins. Seminars in Cancer Biology 11 15-23. (doi:10.1006/scbi.2000.0342)
    • (2001) Seminars in Cancer Biology , vol.11 , pp. 15-23
    • Ali, S.H.1    DeCaprio, J.A.2
  • 4
    • 79953701350 scopus 로고    scopus 로고
    • Neuroendocrine prostate cancer xenografts with large-cell and small-cell features derived from a single patient's tumor: Morphological, immunohistochemical, and gene expression profiles
    • Aparicio A, Tzelepi V, Araujo JC, Guo CC, Liang S, Troncoso P, Logothetis CJ, Navone NM & Maity SN 2011 Neuroendocrine prostate cancer xenografts with large-cell and small-cell features derived from a single patient's tumor: morphological, immunohistochemical, and gene expression profiles. Prostate 71 846-856. (doi:10.1002/pros.21301)
    • (2011) Prostate , vol.71 , pp. 846-856
    • Aparicio, A.1    Tzelepi, V.2    Araujo, J.C.3    Guo, C.C.4    Liang, S.5    Troncoso, P.6    Logothetis, C.J.7    Navone, N.M.8    Maity, S.N.9
  • 5
    • 33645736793 scopus 로고    scopus 로고
    • Genetically engineered models have advantages over xenografts for preclinical studies
    • (discussion 3358-3359)
    • Becher OJ & Holland EC 2006 Genetically engineered models have advantages over xenografts for preclinical studies. Cancer Research 66 3355-3358 (discussion 3358-3359). (doi:10.1158/0008-5472.CAN-05-3827)
    • (2006) Cancer Research , vol.66 , pp. 3355-3358
    • Becher, O.J.1    Holland, E.C.2
  • 6
    • 84902661182 scopus 로고    scopus 로고
    • The N-myc oncogene: Maximizing its targets, regulation, and therapeutic potential
    • Beltran H 2014 The N-myc oncogene: maximizing its targets, regulation, and therapeutic potential. Molecular Cancer Research 12 815-822. (doi:10.1158/1541-7786.MCR-13-0536)
    • (2014) Molecular Cancer Research , vol.12 , pp. 815-822
    • Beltran, H.1
  • 10
    • 38749142915 scopus 로고    scopus 로고
    • Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer
    • Chiaverotti T, Couto SS, Donjacour A, Mao JH, Nagase H, Cardiff RD, Cunha GR & Balmain A 2008 Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer. American Journal of Pathology 172 236-246. (doi:10.2353/ajpath.2008.070602)
    • (2008) American Journal of Pathology , vol.172 , pp. 236-246
    • Chiaverotti, T.1    Couto, S.S.2    Donjacour, A.3    Mao, J.H.4    Nagase, H.5    Cardiff, R.D.6    Cunha, G.R.7    Balmain, A.8
  • 13
    • 14944360231 scopus 로고    scopus 로고
    • Knockin of SV40 tag oncogene in a mouse adenocarcinoma of the prostate model demonstrates advantageous features over the transgenic model
    • Duan W, Gabril MY, Moussa M, Chan FL, Sakai H, Fong G & Xuan JW 2005 Knockin of SV40 Tag oncogene in a mouse adenocarcinoma of the prostate model demonstrates advantageous features over the transgenic model. Oncogene 24 1510-1524. (doi:10.1038/sj.onc.1208229)
    • (2005) Oncogene , vol.24 , pp. 1510-1524
    • Duan, W.1    Gabril, M.Y.2    Moussa, M.3    Chan, F.L.4    Sakai, H.5    Fong, G.6    Xuan, J.W.7
  • 17
    • 84862544685 scopus 로고    scopus 로고
    • Variants and unusual patterns of prostate cancer: Clinicopathologic and differential diagnostic considerations
    • Fine SW 2012 Variants and unusual patterns of prostate cancer: clinicopathologic and differential diagnostic considerations. Advances in Anatomic Pathology 19 204-216. (doi:10.1097/PAP.0b013e31825c6b92)
    • (2012) Advances in Anatomic Pathology , vol.19 , pp. 204-216
    • Fine, S.W.1
  • 18
    • 0036892926 scopus 로고    scopus 로고
    • Prostate targeting: Psp94 gene promoter/enhancer region directed prostate tissue-specific expression in a transgenic mouse prostate cancer model
    • Gabril MY, Onita T, Ji PG, Sakai H, Chan FL, Koropatnick J, Chin JL, Moussa M & Xuan JW 2002 Prostate targeting: PSP94 gene promoter/enhancer region directed prostate tissue-specific expression in a transgenic mouse prostate cancer model. Gene Therapy 9 1589-1599. (doi:10.1038/sj.gt.3301895)
    • (2002) Gene Therapy , vol.9 , pp. 1589-1599
    • Gabril, M.Y.1    Onita, T.2    Ji, P.G.3    Sakai, H.4    Chan, F.L.5    Koropatnick, J.6    Chin, J.L.7    Moussa, M.8    Xuan, J.W.9
  • 19
    • 14044265765 scopus 로고    scopus 로고
    • A novel knock-in prostate cancer model demonstrates biology similar to that of human prostate cancer and suitable for preclinical studies
    • Gabril MY, Duan W, Wu G, Moussa M, Izawa JI, Panchal CJ, Sakai H & Xuan JW 2005 A novel knock-in prostate cancer model demonstrates biology similar to that of human prostate cancer and suitable for preclinical studies. Molecular Therapy 11 348-362. (doi:10.1016/j.ymthe.2004.12.005)
    • (2005) Molecular Therapy , vol.11 , pp. 348-362
    • Gabril, M.Y.1    Duan, W.2    Wu, G.3    Moussa, M.4    Izawa, J.I.5    Panchal, C.J.6    Sakai, H.7    Xuan, J.W.8
  • 20
    • 0032446247 scopus 로고    scopus 로고
    • A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells
    • Garabedian EM, Humphrey PA & Gordon JI 1998 A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells. PNAS 95 15382-15387. (doi:10.1073/pnas.95.26.15382)
    • (1998) PNAS , vol.95 , pp. 15382-15387
    • Garabedian, E.M.1    Humphrey, P.A.2    Gordon, J.I.3
  • 25
    • 0023481234 scopus 로고
    • Xenografted small cell undifferentiated cancer of prostate: Possible common origin with prostatic adenocarcinoma
    • van Haaften-Day C, Raghavan D, Russell P, Wills EJ, Gregory P, Tilley W & Horsfall DJ 1987 Xenografted small cell undifferentiated cancer of prostate: possible common origin with prostatic adenocarcinoma. Prostate 11 271-279. (doi:10.1002/pros.2990110307)
    • (1987) Prostate , vol.11 , pp. 271-279
    • Van Haaften-Day, C.1    Raghavan, D.2    Russell, P.3    Wills, E.J.4    Gregory, P.5    Tilley, W.6    Horsfall, D.J.7
  • 26
    • 0032977146 scopus 로고    scopus 로고
    • Undifferentiated carcinoma of the prostate with small cell features: Immunohistochemical subtyping and reflections on histogenesis
    • Helpap B & Kollermann J 1999 Undifferentiated carcinoma of the prostate with small cell features: immunohistochemical subtyping and reflections on histogenesis. Virchows Archiv 434 385-391. (doi:10.1007/s004280050357)
    • (1999) Virchows Archiv , vol.434 , pp. 385-391
    • Helpap, B.1    Kollermann, J.2
  • 27
    • 0345493852 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in prostatic carcinomas: Histogenesis, biology, clinical relevance, and future therapeutical perspectives
    • Helpap B, Kollermann J & Oehler U 1999 Neuroendocrine differentiation in prostatic carcinomas: histogenesis, biology, clinical relevance, and future therapeutical perspectives. Urologia Internationalis 62 133-138. (doi:10.1159/000030376)
    • (1999) Urologia Internationalis , vol.62 , pp. 133-138
    • Helpap, B.1    Kollermann, J.2    Oehler, U.3
  • 28
    • 28544436228 scopus 로고    scopus 로고
    • Heterogeneous tumor evolution initiated by loss of pRb function in a preclinical prostate cancer model
    • Hill R, Song Y, Cardiff RD & Van Dyke T 2005 Heterogeneous tumor evolution initiated by loss of pRb function in a preclinical prostate cancer model. Cancer Research 65 10243-10254. (doi:10.1158/0008-5472.CAN-05-1579)
    • (2005) Cancer Research , vol.65 , pp. 10243-10254
    • Hill, R.1    Song, Y.2    Cardiff, R.D.3    Van Dyke, T.4
  • 29
    • 0037113943 scopus 로고    scopus 로고
    • Molecular characterization of a metastatic neuroendocrine cell cancer arising in the prostates of transgenic mice
    • Hu Y, Ippolito JE, Garabedian EM, Humphrey PA & Gordon JI 2002 Molecular characterization of a metastatic neuroendocrine cell cancer arising in the prostates of transgenic mice. Journal of Biological Chemistry 277 44462-44474. (doi:10.1074/jbc.M205784200)
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 44462-44474
    • Hu, Y.1    Ippolito, J.E.2    Garabedian, E.M.3    Humphrey, P.A.4    Gordon, J.I.5
  • 30
    • 7444271447 scopus 로고    scopus 로고
    • Gleason grading and prognostic factors in carcinoma of the prostate
    • Humphrey PA 2004 Gleason grading and prognostic factors in carcinoma of the prostate. Modern Pathology 17 292-306. (doi:10.1038/modpathol.3800054)
    • (2004) Modern Pathology , vol.17 , pp. 292-306
    • Humphrey, P.A.1
  • 31
    • 84255199223 scopus 로고    scopus 로고
    • Histological variants of prostatic carcinoma and their significance
    • Humphrey PA 2012 Histological variants of prostatic carcinoma and their significance. Histopathology 60 59-74. (doi:10.1111/j.1365-2559.2011.04039.x)
    • (2012) Histopathology , vol.60 , pp. 59-74
    • Humphrey, P.A.1
  • 32
    • 2942565608 scopus 로고    scopus 로고
    • Neuroendocrine cell differentiation in the CWR22 human prostate cancer xenograft: Association with tumor cell proliferation prior to recurrence
    • Huss WJ, Gregory CW & Smith GJ 2004 Neuroendocrine cell differentiation in the CWR22 human prostate cancer xenograft: association with tumor cell proliferation prior to recurrence. Prostate 60 91-97. (doi:10.1002/pros.20032)
    • (2004) Prostate , vol.60 , pp. 91-97
    • Huss, W.J.1    Gregory, C.W.2    Smith, G.J.3
  • 33
    • 84878108747 scopus 로고    scopus 로고
    • Modeling prostate cancer in mice: Something old, something new, something premalignant, something metastatic
    • Irshad S & Abate-Shen C 2013 Modeling prostate cancer in mice: something old, something new, something premalignant, something metastatic. Cancer Metastasis Reviews 32 109-122. (doi:10.1007/s10555-012-9409-1)
    • (2013) Cancer Metastasis Reviews , vol.32 , pp. 109-122
    • Irshad, S.1    Abate-Shen, C.2
  • 43
    • 0035949707 scopus 로고    scopus 로고
    • Haploinsufficiency of the pten tumor suppressor gene promotes prostate cancer progression
    • Kwabi-Addo B, Giri D, Schmidt K, Podsypanina K, Parsons R, Greenberg N & Ittmann M 2001 Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression. PNAS 98 11563-11568. (doi:10.1073/pnas.201167798)
    • (2001) PNAS , vol.98 , pp. 11563-11568
    • Kwabi-Addo, B.1    Giri, D.2    Schmidt, K.3    Podsypanina, K.4    Parsons, R.5    Greenberg, N.6    Ittmann, M.7
  • 44
    • 84894275509 scopus 로고    scopus 로고
    • High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development
    • Lin D, Wyatt AW, Xue H, Wang Y, Dong X, Haegert A, Wu R, Brahmbhatt S, Mo F, Jong L et al. 2014 High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development. Cancer Research 74 1272-1283. (doi:10.1158/0008-5472.CAN-13-2921-T)
    • (2014) Cancer Research , vol.74 , pp. 1272-1283
    • Lin, D.1    Wyatt, A.W.2    Xue, H.3    Wang, Y.4    Dong, X.5    Haegert, A.6    Wu, R.7    Brahmbhatt, S.8    Mo, F.9    Jong, L.10
  • 45
    • 77950266184 scopus 로고    scopus 로고
    • Matrix metallopro-teinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression
    • Littlepage LE, Sternlicht MD, Rougier N, Phillips J, Gallo E, Yu Y, Williams K, Brenot A, Gordon JI & Werb Z 2010 Matrix metallopro-teinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression. Cancer Research 70 2224-2234. (doi:10.1158/0008-5472.CAN-09-3515)
    • (2010) Cancer Research , vol.70 , pp. 2224-2234
    • Littlepage, L.E.1    Sternlicht, M.D.2    Rougier, N.3    Phillips, J.4    Gallo, E.5    Yu, Y.6    Williams, K.7    Brenot, A.8    Gordon, J.I.9    Werb, Z.10
  • 46
    • 84865330131 scopus 로고    scopus 로고
    • A comprehensive review of incidence and survival in patients with rare histological variants of prostate cancer in the United States from 1973 to 2008
    • Marcus DM, Goodman M, Jani AB, Osunkoya AO & Rossi PJ 2012 A comprehensive review of incidence and survival in patients with rare histological variants of prostate cancer in the United States from 1973 to 2008. Prostate Cancer and Prostatic Diseases 15 283-288. (doi:10.1038/pcan.2012.4)
    • (2012) Prostate Cancer and Prostatic Diseases , vol.15 , pp. 283-288
    • Marcus, D.M.1    Goodman, M.2    Jani, A.B.3    Osunkoya, A.O.4    Rossi, P.J.5
  • 47
    • 0028116952 scopus 로고
    • Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene
    • Maroulakou IG, Anver M, Garrett L & Green JE 1994 Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene. PNAS 91 11236-11240. (doi:10.1073/pnas.91.23.11236)
    • (1994) PNAS , vol.91 , pp. 11236-11240
    • Maroulakou, I.G.1    Anver, M.2    Garrett, L.3    Green, J.E.4
  • 49
    • 0347479267 scopus 로고    scopus 로고
    • An allograft model of androgen independent prostatic neuroendocrine carcinoma derived from a large probasin promoter-T antigen transgenic mouse line
    • Masumori N, Tsuchiya K, Tu WH, Lee C, Kasper S, Tsukamoto T, Shappell SB & Matusik RJ 2004 An allograft model of androgen independent prostatic neuroendocrine carcinoma derived from a large probasin promoter-T antigen transgenic mouse line. Journal of Urology 171 439-442. (doi:10.1097/01.ju.0000099826.63103.94)
    • (2004) Journal of Urology , vol.171 , pp. 439-442
    • Masumori, N.1    Tsuchiya, K.2    Tu, W.H.3    Lee, C.4    Kasper, S.5    Tsukamoto, T.6    Shappell, S.B.7    Matusik, R.J.8
  • 52
    • 0025103372 scopus 로고
    • Polyoma small and middle T antigens and SV40 small T antigen form stable complexes with protein phosphatase 2A
    • Pallas DC, Shahrik LK, Martin BL, Jaspers S, Miller TB, Brautigan DL & Roberts TM 1990 Polyoma small and middle T antigens and SV40 small T antigen form stable complexes with protein phosphatase 2A. Cell 60 167-176. (doi:10.1016/0092-8674(90)90726-U)
    • (1990) Cell , vol.60 , pp. 167-176
    • Pallas, D.C.1    Shahrik, L.K.2    Martin, B.L.3    Jaspers, S.4    Miller, T.B.5    Brautigan, D.L.6    Roberts, T.M.7
  • 53
    • 0014510423 scopus 로고
    • The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept
    • Pearse AG 1969 The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. Journal of Histochemistry and Cytochemistry 17 303-313. (doi:10.1177/17.5.303)
    • (1969) Journal of Histochemistry and Cytochemistry , vol.17 , pp. 303-313
    • Pearse, A.G.1
  • 57
    • 59349112711 scopus 로고    scopus 로고
    • SV40: Cell transformation and tumorigenesis
    • Pipas JM 2009 SV40: cell transformation and tumorigenesis. Virology 384 294-303. (doi:10.1016/j.virol.2008.11.024)
    • (2009) Virology , vol.384 , pp. 294-303
    • Pipas, J.M.1
  • 59
    • 36248971056 scopus 로고    scopus 로고
    • Progression of prostate cancer from a subset of p63-positive basal epithelial cells in FG/Tag transgenic mice
    • Reiner T, de Las Pozas A, Parrondo R & Perez-Stable C 2007 Progression of prostate cancer from a subset of p63-positive basal epithelial cells in FG/Tag transgenic mice. Molecular Cancer Research 5 1171-1179. (doi:10.1158/1541-7786.MCR-07-0024)
    • (2007) Molecular Cancer Research , vol.5 , pp. 1171-1179
    • Reiner, T.1    De Las Pozas, A.2    Parrondo, R.3    Perez-Stable, C.4
  • 60
    • 33645734205 scopus 로고    scopus 로고
    • Contributions of human tumor xenografts to anticancer drug development
    • (discussion 3354)
    • Sausville EA & Burger AM 2006 Contributions of human tumor xenografts to anticancer drug development. Cancer Research 66 3351-3354 (discussion 3354). (doi:10.1158/0008-5472.CAN-05-3627)
    • (2006) Cancer Research , vol.66 , pp. 3351-3354
    • Sausville, E.A.1    Burger, A.M.2
  • 61
    • 59049096202 scopus 로고    scopus 로고
    • Small cell (neuroendocrine) carcinoma of the prostate: Etiology, diagnosis, prognosis, and therapeutic implications - A retrospective study of 30 patients from the rare cancer network
    • Stein ME, Bernstein Z, Abacioglu U, Sengoz M, Miller RC, Meirovitz A, Zouhair A, Freixa SV, Poortmans PH, Ash R et al. 2008 Small cell (neuroendocrine) carcinoma of the prostate: etiology, diagnosis, prognosis, and therapeutic implications - a retrospective study of 30 patients from the rare cancer network. American Journal of Medical Sciences 336 478-488. (doi:10.1097/MAJ.0b013e3181731e58)
    • (2008) American Journal of Medical Sciences , vol.336 , pp. 478-488
    • Stein, M.E.1    Bernstein, Z.2    Abacioglu, U.3    Sengoz, M.4    Miller, R.C.5    Meirovitz, A.6    Zouhair, A.7    Freixa, S.V.8    Poortmans, P.H.9    Ash, R.10
  • 62
    • 18244379285 scopus 로고    scopus 로고
    • An investigation of the effects of late-onset dietary restriction on prostate cancer development in the TRAMP mouse
    • Suttie AW, Dinse GE, Nyska A, Moser GJ, Goldsworthy TL & Maronpot RR 2005 An investigation of the effects of late-onset dietary restriction on prostate cancer development in the TRAMP mouse. Toxicologic Pathology 33 386-397. (doi:10.1080/01926230590930272)
    • (2005) Toxicologic Pathology , vol.33 , pp. 386-397
    • Suttie, A.W.1    Dinse, G.E.2    Nyska, A.3    Moser, G.J.4    Goldsworthy, T.L.5    Maronpot, R.R.6
  • 64
    • 18944363107 scopus 로고    scopus 로고
    • Epithelial-stromal tumor of the seminal vesicles in the transgenic adenocarcinoma mouse prostate model
    • Tani Y, Suttie A, Flake GP, Nyska A & Maronpot RR 2005 Epithelial-stromal tumor of the seminal vesicles in the transgenic adenocarcinoma mouse prostate model. Veterinary Pathology 42 306-314. (doi:10.1354/vp.42-3-306)
    • (2005) Veterinary Pathology , vol.42 , pp. 306-314
    • Tani, Y.1    Suttie, A.2    Flake, G.P.3    Nyska, A.4    Maronpot, R.R.5
  • 67
    • 37549037864 scopus 로고    scopus 로고
    • Small cell carcinoma of the prostate. A morphologic and immunohistochemical study of 95 cases
    • Wang W & Epstein JI 2008 Small cell carcinoma of the prostate. A morphologic and immunohistochemical study of 95 cases. American Journal of Surgical Pathology 32 65-71. (doi:10.1097/PAS.0b013e318058a96b)
    • (2008) American Journal of Surgical Pathology , vol.32 , pp. 65-71
    • Wang, W.1    Epstein, J.I.2
  • 68
    • 0030927430 scopus 로고    scopus 로고
    • Large fragment of the probasin promoter targets high levels of transgene expression to the prostate of transgenic mice
    • Yan Y, Sheppard PC, Kasper S, Lin L, Hoare S, Kapoor A, Dodd JG, Duckworth ML & Matusik RJ 1997 Large fragment of the probasin promoter targets high levels of transgene expression to the prostate of transgenic mice. Prostate 32 129-139. (doi:10.1002/(SICI)1097-0045(19970701)32:2<129::AID-PROS8>3.0.CO;2-H)
    • (1997) Prostate , vol.32 , pp. 129-139
    • Yan, Y.1    Sheppard, P.C.2    Kasper, S.3    Lin, L.4    Hoare, S.5    Kapoor, A.6    Dodd, J.G.7    Duckworth, M.L.8    Matusik, R.J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.