Size and rigidity of cylindrical polymer brushes dictate long circulating properties in vivo

ACS Nano

Volumn 9, Issue 2, 2015, Pages 1294-1304

  Müllner, Markus ^a,c   Dodds, Sarah J ^a,c   Nguyen, Tri Hung ^b,c   Senyschyn, Danielle ^b,c   Porter, Christopher J H ^b,c   Boyd, Ben J ^b,c   Caruso, Frank ^a,c  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c ARC Centre of Excellence in Convergent Bio Nano Science and Technology   (Australia)

Author keywords

anisotropic polymer particles; biodistribution; grafting from; long circulation; macrophages; PEGylation; pharmacokinetics

Indexed keywords

ACRYLIC MONOMERS; ANISOTROPY; ASPECT RATIO; COPPER COMPOUNDS; DENDRIMERS; DEPOSITION; DRUG DELIVERY; ETHYLENE; ETHYLENE GLYCOL; GRAFTING (CHEMICAL); MACROPHAGES; NANOCRYSTALLINE MATERIALS; PARTICLE SIZE; PHARMACOKINETICS; RIGIDITY;

ANISOTROPIC POLYMERS; BIODISTRIBUTIONS; GRAFTING FROM; LONG CIRCULATIONS; PEGYLATION;

PARTICLE SIZE ANALYSIS;

DRUG CARRIER; MACROGOL DERIVATIVE; METHACRYLIC ACID DERIVATIVE; POLYETHYLENE GLYCOL METHACRYLATE; WATER;

ANIMAL; ANISOTROPY; CELL LINE RAW 264.7; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; MALE; METABOLISM; MOUSE; PARTICLE SIZE; PHAGOCYTE; RAT; SOLUBILITY; SPRAGUE DAWLEY RAT; SYNTHESIS; TISSUE DISTRIBUTION;

ANIMALS; ANISOTROPY; DRUG CARRIERS; MALE; METHACRYLATES; MICE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PARTICLE SIZE; PHAGOCYTES; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; RAW 264.7 CELLS; SOLUBILITY; TISSUE DISTRIBUTION; WATER;

EID: 84923420065     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn505125f     Document Type: Article

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