A subset of ventral tegmental area dopamine neurons responds to acute ethanol

Neuroscience

Volumn 290, Issue , 2015, Pages 649-658

  Mrejeru, A ^a   Marti Prats L ^b   Avegno, E M ^a   Harrison, N L ^a   Sulzer, D ^a  

^a Department of Medicine   (United States)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Addiction; Alcohol; Dopamine; Ethanol; Tonic firing; VTA

Indexed keywords

ALCOHOL; DOPAMINE; GREEN FLUORESCENT PROTEIN; QUINPIROLE; CENTRAL DEPRESSANT AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MAPPING; BRAIN NUCLEUS; CELL SUBPOPULATION; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOPAMINERGIC TRANSMISSION; IN VITRO STUDY; INTERFASCICULAR NUCLEUS; LATERAL VENTRAL TEGMENTUM; MEDIAL VENTRAL TEGMENTUM; MOUSE; NERVE POTENTIAL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NONHUMAN; NUCLEUS ACCUMBENS; OSMOLARITY; PARABRACHIAL PIGMENTED NUCLEUS; PARANIGRAL NUCLEUS; PERIKARYON; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; ROSTRAL LINEAR NUCLEUS; SENSITIVITY ANALYSIS; SUBSTANTIA NIGRA; TRANSGENIC MOUSE; VENTRAL TEGMENTUM; VOLTAGE CLAMP TECHNIQUE; ACTION POTENTIAL; ANIMAL; C57BL MOUSE; DOSE RESPONSE; DRUG EFFECTS; GENETICS; METABOLISM; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE;

ACTION POTENTIALS; ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GREEN FLUORESCENT PROTEINS; MICE, INBRED C57BL; MICE, TRANSGENIC; PATCH-CLAMP TECHNIQUES; TISSUE CULTURE TECHNIQUES; VENTRAL TEGMENTAL AREA;

EID: 84923352390     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.12.081     Document Type: Article

References (51)

1. Bjorklund A., Dunnett S.B. Dopamine neuron systems in the brain: an update. Trends Neurosci 2007, 30:194-202.
2. Borgkvist A., Mrejeru A., Sulzer D. Multiple personalities in the ventral tegmental area. Neuron 2011, 70:803-805.
3. Brodie M.S., Shefner S.A., Dunwiddie T.V. Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro. Brain Res 1990, 508:65-69.
4. Carnicella S., Ron D., Barak S. Intermittent ethanol access schedule in rats as a preclinical model of alcohol abuse. Alcohol 2014, 48:243-252.
5. Carta M., Mameli M., Valenzuela C.F. Alcohol enhances GABAergic transmission to cerebellar granule cells via an increase in Golgi cell excitability. J Neurosci 2004, 24:3746-3751.
6. Crabbe J.C., Harris R.A., Koob G.F. Preclinical studies of alcohol binge drinking. Ann N Y Acad Sci 2011, 1216:24-40.
7. Del-Fava F., Hasue R.H., Ferreira J.G., Shammah-Lagnado S.J. Efferent connections of the rostral linear nucleus of the ventral tegmental area in the rat. Neuroscience 2007, 145:1059-1076.
8. Di Chiara G., Imperato A. Ethanol preferentially stimulates dopamine release in the nucleus accumbens of freely moving rats. Eur J Pharmacol 1985, 115:131-132.
9. Ericson M., Lof E., Stomberg R., Chau P., Soderpalm B. Nicotinic acetylcholine receptors in the anterior, but not posterior, ventral tegmental area mediate ethanol-induced elevation of accumbal dopamine levels. J Pharmacol Exp Ther 2008, 326:76-82.
10. Ferreira J.G., Del-Fava F., Hasue R.H., Shammah-Lagnado S.J. Organization of ventral tegmental area projections to the ventral tegmental area-nigral complex in the rat. Neuroscience 2008, 153:196-213.
11. Fields H.L., Hjelmstad G.O., Margolis E.B., Nicola S.M. Ventral tegmental area neurons in learned appetitive behavior and positive reinforcement. Annu Rev Neurosci 2007, 30:289-316.
12. Ford C.P. The role of D2-autoreceptors in regulating dopamine neuron activity and transmission. Neuroscience 2014, 282C:13-22.
13. Ford C.P., Mark G.P., Williams J.T. Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location. J Neurosci 2006, 26:2788-2797.
14. Fu Y., Yuan Y., Halliday G., Rusznak Z., Watson C., Paxinos G. A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse. Brain Struct Funct 2012, 217:591-612.
15. Geisler S., Wise R.A. Functional implications of glutamatergic projections to the ventral tegmental area. Rev Neurosci 2008, 19:227-244.
16. Gessa G.L., Muntoni F., Collu M., Vargiu L., Mereu G. Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res 1985, 348:201-203.
17. Gorelova N., Mulholland P.J., Chandler L.J., Seamans J.K. The glutamatergic component of the mesocortical pathway emanating from different subregions of the ventral midbrain. Cereb Cortex 2012, 22:327-336.
18. Hnasko T.S., Chuhma N., Zhang H., Goh G.Y., Sulzer D., Palmiter R.D., Rayport S., Edwards R.H. Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron 2010, 65:643-656.
19. Khaliq Z.M., Bean B.P. Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances. J Neurosci 2010, 30:7401-7413.
20. Lammel S., Hetzel A., Hackel O., Jones I., Liss B., Roeper J. Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. Neuron 2008, 57:760-773.
21. Lammel S., Ion D.I., Roeper J., Malenka R.C. Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli. Neuron 2011, 70:855-862.
22. Lammel S., Lim B.K., Malenka R.C. Reward and aversion in a heterogeneous midbrain dopamine system. Neuropharmacology 2014, 76(Pt B):351-359.
23. Lecca S., Melis M., Luchicchi A., Muntoni A.L., Pistis M. Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse. Neuropsychopharmacology 2012, 37:1164-1176.
24. Li X., Qi J., Yamaguchi T., Wang H.L., Morales M. Heterogeneous composition of dopamine neurons of the rat A10 region: molecular evidence for diverse signaling properties. Brain Struct Funct 2013, 218:1159-1176.
25. Lodge D.J., Grace A.A. The laterodorsal tegmentum is essential for burst firing of ventral tegmental area dopamine neurons. Proc Natl Acad Sci U S A 2006, 103:5167-5172.
26. Luscher C., Malenka R.C. Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling. Neuron 2011, 69:650-663.
27. Margolis E.B., Lock H., Hjelmstad G.O., Fields H.L. The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons?. J Physiol 2006, 577:907-924.
28. Margolis E.B., Fields H.L., Hjelmstad G.O., Mitchell J.M. Delta-opioid receptor expression in the ventral tegmental area protects against elevated alcohol consumption. J Neurosci 2008, 28:12672-12681.
29. Margolis E.B., Toy B., Himmels P., Morales M., Fields H.L. Identification of rat ventral tegmental area GABAergic neurons. PLoS One 2012, 7:e42365.
30. Marinelli M., McCutcheon J.E. Heterogeneity of dopamine neuron activity across traits and states. Neuroscience 2014, 282C:176-197.
31. h: involvement of barium-sensitive potassium currents. J Neurophysiol 2008, 100:1202-1210.
32. Melis M., Enrico P., Peana A.T., Diana M. Acetaldehyde mediates alcohol activation of the mesolimbic dopamine system. Eur J Neurosci 2007, 26:2824-2833.
33. Melon L.C., Boehm S.L. GABAA receptors in the posterior, but not anterior, ventral tegmental area mediate Ro15-4513-induced attenuation of binge-like ethanol consumption in C57BL/6J female mice. Behav Brain Res 2011, 220:230-237.
34. Mereu G., Gessa G.L. Low doses of ethanol inhibit the firing of neurons in the substantia nigra, pars reticulata: a GABAergic effect?. Brain Res 1985, 360:325-330.
35. Morikawa H., Morrisett R.A. Ethanol action on dopaminergic neurons in the ventral tegmental area: interaction with intrinsic ion channels and neurotransmitter inputs. Int Rev Neurobiol 2010, 91:235-288.
36. Neuhoff H., Neu A., Liss B., Roeper J. I(h) channels contribute to the different functional properties of identified dopaminergic subpopulations in the midbrain. J Neurosci 2002, 22:1290-1302.
37. Nimitvilai S., Arora D.S., You C., McElvain M., Brodie M.S. Phorbol ester reduces ethanol excitation of dopaminergic neurons of the ventral tegmental area: involvement of protein kinase C theta. Front Integr Neurosci 2013, 7:96.
38. h) is an ethanol target in midbrain dopamine neurons of mice. J Neurophysiol 2006, 95:619-626.
39. Paxinos G, Franklin KBJ (2001) The Mouse Brain in Stereotaxic Coordinates. San Diego, CA., USA: Academic Press.
40. Robinson D.L., Howard E.C., McConnell S., Gonzales R.A., Wightman R.M. Disparity between tonic and phasic ethanol-induced dopamine increases in the nucleus accumbens of rats. Alcohol Clin Exp Res 2009, 33:1187-1196.
41. Rodd Z.A., Bell R.L., McQueen V.K., Davids M.R., Hsu C.C., Murphy J.M., Li T.K., Lumeng L., McBride W.J. Prolonged increase in the sensitivity of the posterior ventral tegmental area to the reinforcing effects of ethanol following repeated exposure to cycles of ethanol access and deprivation. J Pharmacol Exp Ther 2005, 315:648-657.
42. Sawamoto K., Nakao N., Kobayashi K., Matsushita N., Takahashi H., Kakishita K., Yamamoto A., Yoshizaki T., Terashima T., Murakami F., Itakura T., Okano H. Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proc Natl Acad Sci U S A 2001, 98:6423-6428.
43. Sesack S.R., Grace A.A. Cortico-Basal Ganglia reward network: microcircuitry. Neuropsychopharmacology 2010, 35:27-47.
44. Sulzer D. How addictive drugs disrupt presynaptic dopamine neurotransmission. Neuron 2011, 69:628-649.
45. Tan K.R., Brown M., Labouebe G., Yvon C., Creton C., Fritschy J.M., Rudolph U., Luscher C. Neural bases for addictive properties of benzodiazepines. Nature 2010, 463:769-774.
46. Trudeau L.E., Hnasko T.S., Wallen-Mackenzie A., Morales M., Rayport S., Sulzer D. The multilingual nature of dopamine neurons. Prog Brain Res 2014, 211:141-164.
47. Ungless M.A., Grace A.A. Are you or aren't you? Challenges associated with physiologically identifying dopamine neurons. Trends Neurosci 2012, 35:422-430.
48. Ungless M.A., Magill P.J., Bolam J.P. Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli. Science 2004, 303:2040-2042.
49. Watabe-Uchida M., Zhu L., Ogawa S.K., Vamanrao A., Uchida N. Whole-brain mapping of direct inputs to midbrain dopamine neurons. Neuron 2012, 74:858-873.
50. Yamaguchi T., Wang H.L., Li X., Ng T.H., Morales M. Mesocorticolimbic glutamatergic pathway. J Neurosci 2011, 31:8476-8490.
51. Zhao-Shea R., Liu L., Soll L.G., Improgo M.R., Meyers E.E., McIntosh J.M., Grady S.R., Marks M.J., Gardner P.D., Tapper A.R. Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area. Neuropsychopharmacology 2011, 36:1021-1032.