메뉴 건너뛰기




Volumn 35, Issue 7, 2012, Pages 422-430

Are you or aren't you? Challenges associated with physiologically identifying dopamine neurons

Author keywords

Basal ganglia; Midbrain; Reward; Substantia nigra; VTA

Indexed keywords

DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; HUMAN; LEARNING; MOTIVATION; NEUROANATOMY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; REVIEW; REWARD; SCHIZOPHRENIA; SUBSTANTIA NIGRA PARS COMPACTA; VENTRAL TEGMENTUM;

EID: 84862766564     PISSN: 01662236     EISSN: 1878108X     Source Type: Journal    
DOI: 10.1016/j.tins.2012.02.003     Document Type: Review
Times cited : (333)

References (82)
  • 1
    • 34247523368 scopus 로고    scopus 로고
    • Behavioral dopamine signals
    • Schultz W. Behavioral dopamine signals. Trends Neurosci. 2007, 30:203-210.
    • (2007) Trends Neurosci. , vol.30 , pp. 203-210
    • Schultz, W.1
  • 2
    • 34247517910 scopus 로고    scopus 로고
    • Regulation of firing of dopaminergic neurons and control of goal-directed behaviors
    • Grace A.A., et al. Regulation of firing of dopaminergic neurons and control of goal-directed behaviors. Trends Neurosci. 2007, 30:220-227.
    • (2007) Trends Neurosci. , vol.30 , pp. 220-227
    • Grace, A.A.1
  • 3
    • 2642519680 scopus 로고    scopus 로고
    • Dopamine, learning and motivation
    • Wise R.A. Dopamine, learning and motivation. Nat. Rev. Neurosci. 2004, 5:483-494.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 483-494
    • Wise, R.A.1
  • 4
    • 0026751059 scopus 로고
    • Dopaminergic mechanisms in the pathogenesis of schizophrenia
    • Goldstein M., Deutch A.Y. Dopaminergic mechanisms in the pathogenesis of schizophrenia. FASEB J. 1992, 6:2413-2421.
    • (1992) FASEB J. , vol.6 , pp. 2413-2421
    • Goldstein, M.1    Deutch, A.Y.2
  • 5
    • 33748371601 scopus 로고    scopus 로고
    • Neural mechanisms of addiction: the role of reward-related learning and memory
    • Hyman S.E., et al. Neural mechanisms of addiction: the role of reward-related learning and memory. Annu. Rev. Neurosci. 2006, 29:565-598.
    • (2006) Annu. Rev. Neurosci. , vol.29 , pp. 565-598
    • Hyman, S.E.1
  • 6
    • 0028792245 scopus 로고
    • GABAergic neurons in the rat pontomesencephalic tegmentum: codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus
    • Ford B., et al. GABAergic neurons in the rat pontomesencephalic tegmentum: codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus. J. Comp. Neurol. 1995, 363:177-196.
    • (1995) J. Comp. Neurol. , vol.363 , pp. 177-196
    • Ford, B.1
  • 7
    • 0027471275 scopus 로고
    • Neurotransmitter regulation of dopamine neurons in the ventral tegmental area
    • Kalivas P.W. Neurotransmitter regulation of dopamine neurons in the ventral tegmental area. Brain Res. Brain Res. Rev. 1993, 18:75-113.
    • (1993) Brain Res. Brain Res. Rev. , vol.18 , pp. 75-113
    • Kalivas, P.W.1
  • 8
    • 41549107882 scopus 로고    scopus 로고
    • Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat
    • Nair-Roberts R.G., et al. Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat. Neuroscience 2008, 152:1024-1031.
    • (2008) Neuroscience , vol.152 , pp. 1024-1031
    • Nair-Roberts, R.G.1
  • 9
    • 33846186743 scopus 로고    scopus 로고
    • Glutamatergic neurons are present in the rat ventral tegmental area
    • Yamaguchi T., et al. Glutamatergic neurons are present in the rat ventral tegmental area. Eur. J. Neurosci. 2007, 25:106-118.
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 106-118
    • Yamaguchi, T.1
  • 10
    • 0020558538 scopus 로고
    • Intracellular and extracellular electrophysiology of nigral dopaminergic neurons. 1. Identification and characterization
    • Grace A.A., Bunney B.S. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons. 1. Identification and characterization. Neuroscience 1983, 10:301-315.
    • (1983) Neuroscience , vol.10 , pp. 301-315
    • Grace, A.A.1    Bunney, B.S.2
  • 11
    • 0015742027 scopus 로고
    • Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity
    • Bunney B.S., et al. Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity. J. Pharmacol. Exp. Ther. 1973, 185:560-571.
    • (1973) J. Pharmacol. Exp. Ther. , vol.185 , pp. 560-571
    • Bunney, B.S.1
  • 12
    • 0035811464 scopus 로고    scopus 로고
    • Dopamine responses comply with basic assumptions of formal learning theory
    • Waelti P., et al. Dopamine responses comply with basic assumptions of formal learning theory. Nature 2001, 412:43-48.
    • (2001) Nature , vol.412 , pp. 43-48
    • Waelti, P.1
  • 13
    • 14844349975 scopus 로고    scopus 로고
    • Adaptive coding of reward value by dopamine neurons
    • Tobler P.N., et al. Adaptive coding of reward value by dopamine neurons. Science 2005, 307:1642-1645.
    • (2005) Science , vol.307 , pp. 1642-1645
    • Tobler, P.N.1
  • 14
    • 36448968271 scopus 로고    scopus 로고
    • Dopamine neurons encode the better option in rats deciding between differently delayed or sized rewards
    • Roesch M.R., et al. Dopamine neurons encode the better option in rats deciding between differently delayed or sized rewards. Nat. Neurosci. 2007, 10:1615-1624.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1615-1624
    • Roesch, M.R.1
  • 15
    • 67349098495 scopus 로고    scopus 로고
    • Two types of dopamine neuron distinctly convey positive and negative motivational signals
    • Matsumoto M., Hikosaka O. Two types of dopamine neuron distinctly convey positive and negative motivational signals. Nature 2009, 459:837-841.
    • (2009) Nature , vol.459 , pp. 837-841
    • Matsumoto, M.1    Hikosaka, O.2
  • 16
    • 0036774104 scopus 로고    scopus 로고
    • Firing modes of midbrain dopamine cells in the freely moving rat
    • Hyland B.I., et al. Firing modes of midbrain dopamine cells in the freely moving rat. Neuroscience 2002, 114:475-492.
    • (2002) Neuroscience , vol.114 , pp. 475-492
    • Hyland, B.I.1
  • 17
    • 79951909857 scopus 로고    scopus 로고
    • Convergent processing of both positive and negative motivational signals by the VTA dopamine neuronal populations
    • Wang D.V., Tsien J.Z. Convergent processing of both positive and negative motivational signals by the VTA dopamine neuronal populations. PLoS ONE 2011, 6:e17047.
    • (2011) PLoS ONE , vol.6
    • Wang, D.V.1    Tsien, J.Z.2
  • 18
    • 0345255891 scopus 로고    scopus 로고
    • Coding of predicted reward omission by dopamine neurons in a conditioned inhibition paradigm
    • Tobler P.N., et al. Coding of predicted reward omission by dopamine neurons in a conditioned inhibition paradigm. J. Neurosci. 2003, 23:10402-10410.
    • (2003) J. Neurosci. , vol.23 , pp. 10402-10410
    • Tobler, P.N.1
  • 19
    • 33747585633 scopus 로고    scopus 로고
    • Midbrain dopamine neurons encode decisions for future action
    • Morris G., et al. Midbrain dopamine neurons encode decisions for future action. Nat. Neurosci. 2006, 9:1057-1063.
    • (2006) Nat. Neurosci. , vol.9 , pp. 1057-1063
    • Morris, G.1
  • 20
    • 0025077453 scopus 로고
    • The effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons
    • Hollerman J.R., Grace A.A. The effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons. Brain Res. 1990, 533:203-212.
    • (1990) Brain Res. , vol.533 , pp. 203-212
    • Hollerman, J.R.1    Grace, A.A.2
  • 21
    • 80052153841 scopus 로고    scopus 로고
    • Antipsychotic drugs rapidly induce dopamine neuron depolarization block in a developmental rat model of schizophrenia
    • Valenti O., et al. Antipsychotic drugs rapidly induce dopamine neuron depolarization block in a developmental rat model of schizophrenia. J. Neurosci. 2011, 31:12330-12338.
    • (2011) J. Neurosci. , vol.31 , pp. 12330-12338
    • Valenti, O.1
  • 22
    • 35448996395 scopus 로고    scopus 로고
    • Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia
    • Lodge D.J., Grace A.A. Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia. J. Neurosci. 2007, 27:11424-11430.
    • (2007) J. Neurosci. , vol.27 , pp. 11424-11430
    • Lodge, D.J.1    Grace, A.A.2
  • 23
    • 0034551773 scopus 로고    scopus 로고
    • Enhanced vulnerability to cocaine self-administration is associated with elevated impulse activity of midbrain dopamine neurons
    • Marinelli M., White F.J. Enhanced vulnerability to cocaine self-administration is associated with elevated impulse activity of midbrain dopamine neurons. J. Neurosci. 2000, 20:8876-8885.
    • (2000) J. Neurosci. , vol.20 , pp. 8876-8885
    • Marinelli, M.1    White, F.J.2
  • 24
    • 1642404961 scopus 로고    scopus 로고
    • Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli
    • Ungless M.A., et al. Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli. Science 2004, 303:2040-2042.
    • (2004) Science , vol.303 , pp. 2040-2042
    • Ungless, M.A.1
  • 25
    • 63849268432 scopus 로고    scopus 로고
    • Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli
    • Brischoux F., et al. Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:4894-4899.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 4894-4899
    • Brischoux, F.1
  • 26
    • 38349155757 scopus 로고    scopus 로고
    • Novel neurons in ventral tegmental area fire selectively during the active phase of the diurnal cycle
    • Luo A.H., et al. Novel neurons in ventral tegmental area fire selectively during the active phase of the diurnal cycle. Eur. J. Neurosci. 2008, 27:408-422.
    • (2008) Eur. J. Neurosci. , vol.27 , pp. 408-422
    • Luo, A.H.1
  • 27
    • 79960518252 scopus 로고    scopus 로고
    • Linking context with reward: a functional circuit from hippocampal CA3 to ventral tegmental area
    • Luo A.H., et al. Linking context with reward: a functional circuit from hippocampal CA3 to ventral tegmental area. Science 2011, 333:353-357.
    • (2011) Science , vol.333 , pp. 353-357
    • Luo, A.H.1
  • 28
    • 78449260551 scopus 로고    scopus 로고
    • Orexin/hypocretin modulates response of ventral tegmental dopamine neurons to prefrontal activation: diurnal influences
    • Moorman D.E., Aston-Jones G. Orexin/hypocretin modulates response of ventral tegmental dopamine neurons to prefrontal activation: diurnal influences. J. Neurosci. 2010, 30:15585-15599.
    • (2010) J. Neurosci. , vol.30 , pp. 15585-15599
    • Moorman, D.E.1    Aston-Jones, G.2
  • 29
    • 79956316450 scopus 로고    scopus 로고
    • Duration of inhibition of ventral tegmental area dopamine neurons encodes a level of conditioned fear
    • Mileykovskiy B., Morales M. Duration of inhibition of ventral tegmental area dopamine neurons encodes a level of conditioned fear. J. Neurosci. 2011, 31:7471-7476.
    • (2011) J. Neurosci. , vol.31 , pp. 7471-7476
    • Mileykovskiy, B.1    Morales, M.2
  • 30
    • 8444231365 scopus 로고    scopus 로고
    • Dopamine: the salient issue
    • Ungless M.A. Dopamine: the salient issue. Trends Neurosci. 2004, 27:702-706.
    • (2004) Trends Neurosci. , vol.27 , pp. 702-706
    • Ungless, M.A.1
  • 31
    • 78650167716 scopus 로고    scopus 로고
    • Reliability in the identification of midbrain dopamine neurons
    • Margolis E.B., et al. Reliability in the identification of midbrain dopamine neurons. PLoS ONE 2010, 5:e15222.
    • (2010) PLoS ONE , vol.5
    • Margolis, E.B.1
  • 32
    • 33845305449 scopus 로고    scopus 로고
    • The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons?
    • Margolis E.B., et al. The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons?. J. Physiol. 2006, 577:907-924.
    • (2006) J. Physiol. , vol.577 , pp. 907-924
    • Margolis, E.B.1
  • 33
    • 77956933260 scopus 로고    scopus 로고
    • In vitro identification and electrophysiological characterization of dopamine neurons in the ventral tegmental area
    • Zhang T.A., et al. In vitro identification and electrophysiological characterization of dopamine neurons in the ventral tegmental area. Neuropharmacology 2010, 59:431-436.
    • (2010) Neuropharmacology , vol.59 , pp. 431-436
    • Zhang, T.A.1
  • 34
    • 0018143270 scopus 로고
    • Antidromic identification of dopaminergic and other output neurons of the rat substantia nigra
    • Guyenet P.G., Aghajanian G.K. Antidromic identification of dopaminergic and other output neurons of the rat substantia nigra. Brain Res. 1978, 150:69-84.
    • (1978) Brain Res. , vol.150 , pp. 69-84
    • Guyenet, P.G.1    Aghajanian, G.K.2
  • 35
    • 0019121565 scopus 로고
    • Nigral dopamine neurons: intracellular recording and identification with L-dopa injection and histofluorescence
    • Grace A.A., Bunney B.S. Nigral dopamine neurons: intracellular recording and identification with L-dopa injection and histofluorescence. Science 1980, 210:654-656.
    • (1980) Science , vol.210 , pp. 654-656
    • Grace, A.A.1    Bunney, B.S.2
  • 36
    • 0018116725 scopus 로고
    • Acute and chronic haloperidol treatment: comparison of effects on nigral dopaminergic cell activity
    • Bunney B.S., Grace A.A. Acute and chronic haloperidol treatment: comparison of effects on nigral dopaminergic cell activity. Life Sci. 1978, 23:1715-1727.
    • (1978) Life Sci. , vol.23 , pp. 1715-1727
    • Bunney, B.S.1    Grace, A.A.2
  • 37
    • 0041859307 scopus 로고    scopus 로고
    • Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission
    • Floresco S.B., et al. Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission. Nat. Neurosci. 2003, 6:968-973.
    • (2003) Nat. Neurosci. , vol.6 , pp. 968-973
    • Floresco, S.B.1
  • 38
    • 0035400083 scopus 로고    scopus 로고
    • Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons
    • Floresco S.B., et al. Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons. J. Neurosci. 2001, 21:4915-4922.
    • (2001) J. Neurosci. , vol.21 , pp. 4915-4922
    • Floresco, S.B.1
  • 39
    • 0020514306 scopus 로고
    • Intracellular and extracellular electrophysiology of nigral dopaminergic neurons. 2. Action potential generating mechanisms and morphological correlates
    • Grace A.A., Bunney B.S. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons. 2. Action potential generating mechanisms and morphological correlates. Neuroscience 1983, 10:317-331.
    • (1983) Neuroscience , vol.10 , pp. 317-331
    • Grace, A.A.1    Bunney, B.S.2
  • 40
    • 63849221600 scopus 로고    scopus 로고
    • Activity of neurochemically heterogeneous dopaminergic neurons in the substantia nigra during spontaneous and driven changes in brain state
    • Brown M.T., et al. Activity of neurochemically heterogeneous dopaminergic neurons in the substantia nigra during spontaneous and driven changes in brain state. J. Neurosci. 2009, 29:2915-2925.
    • (2009) J. Neurosci. , vol.29 , pp. 2915-2925
    • Brown, M.T.1
  • 41
    • 0029866587 scopus 로고    scopus 로고
    • A novel single-cell staining procedure performed in vivo under electrophysiological control: morpho-functional features of juxtacellularly labeled thalamic cells and other central neurons with biocytin or Neurobiotin
    • Pinault D. A novel single-cell staining procedure performed in vivo under electrophysiological control: morpho-functional features of juxtacellularly labeled thalamic cells and other central neurons with biocytin or Neurobiotin. J. Neurosci. Methods 1996, 65:113-136.
    • (1996) J. Neurosci. Methods , vol.65 , pp. 113-136
    • Pinault, D.1
  • 42
    • 0021164524 scopus 로고
    • Evidence for the absence of impulse-regulating somatodendritic and synthesis-modulating nerve terminal autoreceptors on subpopulations of mesocortical dopamine neurons
    • Chiodo L.A., et al. Evidence for the absence of impulse-regulating somatodendritic and synthesis-modulating nerve terminal autoreceptors on subpopulations of mesocortical dopamine neurons. Neuroscience 1984, 12:1-16.
    • (1984) Neuroscience , vol.12 , pp. 1-16
    • Chiodo, L.A.1
  • 43
    • 0032188850 scopus 로고    scopus 로고
    • Electrophysiological characterization of GABAergic neurons in the ventral tegmental area
    • Steffensen S.C., et al. Electrophysiological characterization of GABAergic neurons in the ventral tegmental area. J. Neurosci. 1998, 18:8003-8015.
    • (1998) J. Neurosci. , vol.18 , pp. 8003-8015
    • Steffensen, S.C.1
  • 44
    • 33748449116 scopus 로고    scopus 로고
    • Particular subpopulations of midbrain and hypothalamic dopamine neurons express vesicular glutamate transporter 2 in the rat brain
    • Kawano M., et al. Particular subpopulations of midbrain and hypothalamic dopamine neurons express vesicular glutamate transporter 2 in the rat brain. J. Comp. Neurol. 2006, 498:581-592.
    • (2006) J. Comp. Neurol. , vol.498 , pp. 581-592
    • Kawano, M.1
  • 45
    • 79958288081 scopus 로고    scopus 로고
    • Mesocorticolimbic glutamatergic pathway
    • Yamaguchi T., et al. Mesocorticolimbic glutamatergic pathway. J. Neurosci. 2011, 31:8476-8490.
    • (2011) J. Neurosci. , vol.31 , pp. 8476-8490
    • Yamaguchi, T.1
  • 46
    • 84862773919 scopus 로고    scopus 로고
    • An enhancement of the firing activity of dopamine neurons as a common denominator of antidepressant treatments?
    • Chenu F., et al. An enhancement of the firing activity of dopamine neurons as a common denominator of antidepressant treatments?. Int. J. Neuropsychopharmacol. 2011, 12:1-3.
    • (2011) Int. J. Neuropsychopharmacol. , vol.12 , pp. 1-3
    • Chenu, F.1
  • 47
    • 82255179147 scopus 로고    scopus 로고
    • Expectancy-related changes in firing of dopamine neurons depend on orbitofrontal cortex
    • Takahashi Y.K., et al. Expectancy-related changes in firing of dopamine neurons depend on orbitofrontal cortex. Nat. Neurosci. 2011, 14:1590-1597.
    • (2011) Nat. Neurosci. , vol.14 , pp. 1590-1597
    • Takahashi, Y.K.1
  • 48
    • 79960784151 scopus 로고    scopus 로고
    • Distinct cellular properties of identified dopaminergic and GABAergic neurons in the mouse ventral tegmental area
    • Chieng B., et al. Distinct cellular properties of identified dopaminergic and GABAergic neurons in the mouse ventral tegmental area. J. Physiol. 2011, 589:3775-3787.
    • (2011) J. Physiol. , vol.589 , pp. 3775-3787
    • Chieng, B.1
  • 49
    • 0025029642 scopus 로고
    • Evidence for the functional compartmentalization of spike generating regions of rat midbrain dopamine neurons recorded in vitro
    • Grace A.A. Evidence for the functional compartmentalization of spike generating regions of rat midbrain dopamine neurons recorded in vitro. Brain Res. 1990, 524:31-41.
    • (1990) Brain Res. , vol.524 , pp. 31-41
    • Grace, A.A.1
  • 50
    • 33645511414 scopus 로고    scopus 로고
    • The laterodorsal tegmentum is essential for burst firing of ventral tegmental area dopamine neurons
    • Lodge D.J., Grace A.A. The laterodorsal tegmentum is essential for burst firing of ventral tegmental area dopamine neurons. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:5167-5172.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 5167-5172
    • Lodge, D.J.1    Grace, A.A.2
  • 51
    • 0024459687 scopus 로고
    • Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro
    • Grace A.A., Onn S.P. Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro. J. Neurosci. 1989, 9:3463-3481.
    • (1989) J. Neurosci. , vol.9 , pp. 3463-3481
    • Grace, A.A.1    Onn, S.P.2
  • 52
    • 80052262462 scopus 로고    scopus 로고
    • Spike frequency adaptation is developmentally regulated in substantia nigra pars compacta dopaminergic neurons
    • Vandecasteele M., et al. Spike frequency adaptation is developmentally regulated in substantia nigra pars compacta dopaminergic neurons. Neuroscience 2011, 192:1-10.
    • (2011) Neuroscience , vol.192 , pp. 1-10
    • Vandecasteele, M.1
  • 53
    • 0031029463 scopus 로고    scopus 로고
    • A subset of ventral tegmental area neurons is inhibited by dopamine, 5-hydroxytryptamine and opioids
    • Cameron D.L., et al. A subset of ventral tegmental area neurons is inhibited by dopamine, 5-hydroxytryptamine and opioids. Neuroscience 1997, 77:155-166.
    • (1997) Neuroscience , vol.77 , pp. 155-166
    • Cameron, D.L.1
  • 54
    • 40249097514 scopus 로고    scopus 로고
    • Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system
    • Lammel S., et al. Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. Neuron 2008, 57:760-773.
    • (2008) Neuron , vol.57 , pp. 760-773
    • Lammel, S.1
  • 55
    • 79955762733 scopus 로고    scopus 로고
    • Nicotine potentiation of excitatory inputs to ventral tegmental area dopamine neurons
    • Mao D., et al. Nicotine potentiation of excitatory inputs to ventral tegmental area dopamine neurons. J. Neurosci. 2011, 31:6710-6720.
    • (2011) J. Neurosci. , vol.31 , pp. 6710-6720
    • Mao, D.1
  • 56
    • 42149150944 scopus 로고    scopus 로고
    • Corticotropin-releasing factor increases mouse ventral tegmental area dopamine neuron firing through a protein kinase C-dependent enhancement of Ih
    • Wanat M.J., et al. Corticotropin-releasing factor increases mouse ventral tegmental area dopamine neuron firing through a protein kinase C-dependent enhancement of Ih. J. Physiol. 2008, 586:2157-2170.
    • (2008) J. Physiol. , vol.586 , pp. 2157-2170
    • Wanat, M.J.1
  • 57
    • 12144286982 scopus 로고    scopus 로고
    • Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons
    • Zhao S., et al. Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons. Eur. J. Neurosci. 2004, 19:1133-1140.
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1133-1140
    • Zhao, S.1
  • 58
    • 0036067524 scopus 로고    scopus 로고
    • Dynamics of tyrosine hydroxylase promoter activity during midbrain dopaminergic neuron development
    • Matsushita N., et al. Dynamics of tyrosine hydroxylase promoter activity during midbrain dopaminergic neuron development. J. Neurochem. 2002, 82:295-304.
    • (2002) J. Neurochem. , vol.82 , pp. 295-304
    • Matsushita, N.1
  • 59
    • 79960159955 scopus 로고    scopus 로고
    • Optogenetics in neural systems
    • Yizhar O., et al. Optogenetics in neural systems. Neuron 2011, 71:9-34.
    • (2011) Neuron , vol.71 , pp. 9-34
    • Yizhar, O.1
  • 60
    • 66249125042 scopus 로고    scopus 로고
    • Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning
    • Tsai H.C., et al. Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science 2009, 324:1080-1084.
    • (2009) Science , vol.324 , pp. 1080-1084
    • Tsai, H.C.1
  • 61
    • 77953766302 scopus 로고    scopus 로고
    • Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate
    • Stuber G.D., et al. Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate. J. Neurosci. 2011, 30:8229-8233.
    • (2011) J. Neurosci. , vol.30 , pp. 8229-8233
    • Stuber, G.D.1
  • 62
    • 77952595640 scopus 로고    scopus 로고
    • Glutamatergic signaling by mesolimbic dopamine neurons in the nucleus accumbens
    • Tecuapetla F., et al. Glutamatergic signaling by mesolimbic dopamine neurons in the nucleus accumbens. J. Neurosci. 2011, 30:7105-7110.
    • (2011) J. Neurosci. , vol.30 , pp. 7105-7110
    • Tecuapetla, F.1
  • 63
    • 84856431209 scopus 로고    scopus 로고
    • Neuron-type-specific signals for reward and punishment in the ventral tegmental area
    • Cohen J.Y., et al. Neuron-type-specific signals for reward and punishment in the ventral tegmental area. Nature 2012, 482:85-88.
    • (2012) Nature , vol.482 , pp. 85-88
    • Cohen, J.Y.1
  • 64
    • 0020421621 scopus 로고
    • The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat
    • Swanson L.W. The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat. Brain Res. Bull. 1982, 9:321-353.
    • (1982) Brain Res. Bull. , vol.9 , pp. 321-353
    • Swanson, L.W.1
  • 65
    • 0023256181 scopus 로고
    • Ventral tegmental (A10) system: neurobiology 1. Anatomy and connectivity
    • Oades R.D., Halliday G.M. Ventral tegmental (A10) system: neurobiology 1. Anatomy and connectivity. Brain Res. 1987, 434:117-165.
    • (1987) Brain Res. , vol.434 , pp. 117-165
    • Oades, R.D.1    Halliday, G.M.2
  • 66
    • 36148977592 scopus 로고    scopus 로고
    • Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex
    • Ikemoto S. Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. Brain Res. Rev. 2007, 56:27-78.
    • (2007) Brain Res. Rev. , vol.56 , pp. 27-78
    • Ikemoto, S.1
  • 67
    • 77956022861 scopus 로고    scopus 로고
    • Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain
    • Di Salvio M., et al. Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain. Int. J. Dev. Biol. 2010, 54:939-945.
    • (2010) Int. J. Dev. Biol. , vol.54 , pp. 939-945
    • Di Salvio, M.1
  • 68
    • 0025311057 scopus 로고
    • Cholecystokinin and neurotensin mRNAs are differentially expressed in subnuclei of the ventral tegmental area
    • Jayaraman A., et al. Cholecystokinin and neurotensin mRNAs are differentially expressed in subnuclei of the ventral tegmental area. J. Comp. Neurol. 1990, 296:291-302.
    • (1990) J. Comp. Neurol. , vol.296 , pp. 291-302
    • Jayaraman, A.1
  • 69
    • 79958055503 scopus 로고    scopus 로고
    • Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli
    • Lammel S., et al. Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli. Neuron 2011, 70:855-862.
    • (2011) Neuron , vol.70 , pp. 855-862
    • Lammel, S.1
  • 70
    • 54049129747 scopus 로고    scopus 로고
    • Midbrain dopamine neurons: projection target determines action potential duration and dopamine D(2) receptor inhibition
    • Margolis E.B., et al. Midbrain dopamine neurons: projection target determines action potential duration and dopamine D(2) receptor inhibition. J. Neurosci. 2008, 28:8908-8913.
    • (2008) J. Neurosci. , vol.28 , pp. 8908-8913
    • Margolis, E.B.1
  • 71
    • 33644832076 scopus 로고    scopus 로고
    • Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location
    • Ford C.P., et al. Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location. J. Neurosci. 2006, 26:2788-2797.
    • (2006) J. Neurosci. , vol.26 , pp. 2788-2797
    • Ford, C.P.1
  • 72
    • 33644526563 scopus 로고    scopus 로고
    • Kappa opioids selectively control dopaminergic neurons projecting to the prefrontal cortex
    • Margolis E.B., et al. Kappa opioids selectively control dopaminergic neurons projecting to the prefrontal cortex. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:2938-2942.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 2938-2942
    • Margolis, E.B.1
  • 73
    • 58149236469 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic classical conditioning trials
    • Joshua M., et al. Midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic classical conditioning trials. J. Neurosci. 2008, 28:11673-11684.
    • (2008) J. Neurosci. , vol.28 , pp. 11673-11684
    • Joshua, M.1
  • 74
    • 79952774058 scopus 로고    scopus 로고
    • Aversive stimuli alter ventral tegmental area dopamine neuron activity via a common action in the ventral hippocampus
    • Valenti O., et al. Aversive stimuli alter ventral tegmental area dopamine neuron activity via a common action in the ventral hippocampus. J. Neurosci. 2011, 31:4280-4289.
    • (2011) J. Neurosci. , vol.31 , pp. 4280-4289
    • Valenti, O.1
  • 75
    • 77952595640 scopus 로고    scopus 로고
    • Glutamatergic signaling by mesolimbic dopamine neurons in the nucleus accumbens
    • Tecuapetla F., et al. Glutamatergic signaling by mesolimbic dopamine neurons in the nucleus accumbens. J. Neurosci. 2010, 30:7105-7110.
    • (2010) J. Neurosci. , vol.30 , pp. 7105-7110
    • Tecuapetla, F.1
  • 76
    • 0015538589 scopus 로고
    • Application of the glyoxylic acid method to vibratome sections for the improved visualization of central catecholamine neurons
    • Lindvall O., et al. Application of the glyoxylic acid method to vibratome sections for the improved visualization of central catecholamine neurons. Histochemie 1973, 35:31-38.
    • (1973) Histochemie , vol.35 , pp. 31-38
    • Lindvall, O.1
  • 77
    • 0035282952 scopus 로고    scopus 로고
    • Discharge profiles of ventral tegmental area GABA neurons during movement, anesthesia, and the sleep-wake cycle
    • Lee R.S., et al. Discharge profiles of ventral tegmental area GABA neurons during movement, anesthesia, and the sleep-wake cycle. J. Neurosci. 2001, 21:1757-1766.
    • (2001) J. Neurosci. , vol.21 , pp. 1757-1766
    • Lee, R.S.1
  • 78
    • 62449096945 scopus 로고    scopus 로고
    • Human substantia nigra neurons encode unexpected financial rewards
    • Zaghloul K.A., et al. Human substantia nigra neurons encode unexpected financial rewards. Science 2009, 323:1496-1499.
    • (2009) Science , vol.323 , pp. 1496-1499
    • Zaghloul, K.A.1
  • 79
    • 0026689870 scopus 로고
    • Two types of neurone in the rat ventral tegmental area and their synaptic inputs
    • Johnson S.W., North R.A. Two types of neurone in the rat ventral tegmental area and their synaptic inputs. J. Physiol. 1992, 450:455-468.
    • (1992) J. Physiol. , vol.450 , pp. 455-468
    • Johnson, S.W.1    North, R.A.2
  • 80
    • 0020604515 scopus 로고
    • Intracellular and extracellular electrophysiology of nigral dopaminergic neurons. 3. Evidence for electrotonic coupling
    • Grace A.A., Bunney B.S. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons. 3. Evidence for electrotonic coupling. Neuroscience 1983, 10:333-348.
    • (1983) Neuroscience , vol.10 , pp. 333-348
    • Grace, A.A.1    Bunney, B.S.2
  • 81
    • 0023406642 scopus 로고
    • Electrophysiologically identified nigral dopaminergic neurons intracellularly labeled with HRP: light-microscopic analysis
    • Tepper J.M., et al. Electrophysiologically identified nigral dopaminergic neurons intracellularly labeled with HRP: light-microscopic analysis. J. Neurosci. 1987, 7:2794-2806.
    • (1987) J. Neurosci. , vol.7 , pp. 2794-2806
    • Tepper, J.M.1
  • 82
    • 0021718376 scopus 로고
    • The control of firing pattern in nigral dopamine neurons: burst firing
    • Grace A.A., Bunney B.S. The control of firing pattern in nigral dopamine neurons: burst firing. J. Neurosci. 1984, 4:2877-2890.
    • (1984) J. Neurosci. , vol.4 , pp. 2877-2890
    • Grace, A.A.1    Bunney, B.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.