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Volumn 463, Issue 7282, 2010, Pages 769-774

Neural bases for addictive properties of benzodiazepines

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE DERIVATIVE; FLUMAZENIL; MIDAZOLAM; ZOLPIDEM;

EID: 76749109881     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08758     Document Type: Article
Times cited : (299)

References (48)
  • 1
    • 33845329490 scopus 로고    scopus 로고
    • The mechanistic classification of addictive drugs
    • Lüscher, C. & Ungless, M. A. The mechanistic classification of addictive drugs. PLoS Med. 3, e437 (2006).
    • (2006) PLoS Med. , vol.3
    • Lüscher, C.1    Ungless, M.A.2
  • 2
    • 14844288465 scopus 로고    scopus 로고
    • Benzodiazepine use, abuse, and dependence
    • O'Brien, C. P. Benzodiazepine use, abuse, and dependence. J. Clin. Psychiatry 66 (suppl. 2), 28-33 (2005).
    • (2005) J. Clin. Psychiatry 66 , Issue.SUPPL. 2 , pp. 28-33
    • O'Brien, C.P.1
  • 3
    • 0037456565 scopus 로고    scopus 로고
    • Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons
    • Saal, D., Dong, Y., Bonci, A. & Malenka, R. C. Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons. Neuron 37, 577-582 (2003).
    • (2003) Neuron , vol.37 , pp. 577-582
    • Saal, D.1    Dong, Y.2    Bonci, A.3    Malenka, R.C.4
  • 4
    • 33745183876 scopus 로고    scopus 로고
    • Cocaine triggered AMPA receptor redistribution is reversed in vivo by mGluR-dependent long-term depression
    • Bellone, C. & Lüscher, C. Cocaine triggered AMPA receptor redistribution is reversed in vivo by mGluR-dependent long-term depression. Nature Neurosci. 9, 636-641 (2006).
    • (2006) Nature Neurosci. , vol.9 , pp. 636-641
    • Bellone, C.1    Lüscher, C.2
  • 5
    • 55249094419 scopus 로고    scopus 로고
    • And time course of cocaine-induced long-term potentiation in the ventral tegmental area
    • Argilli, E., Sibley, D. R., Malenka, R. C., England, P. M. & Bonci, A. Mechanism and time course of cocaine-induced long-term potentiation in the ventral tegmental area. J. Neurosci. 28, 9092-9100 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 9092-9100
    • Argilli, E.1    Sibley, D.R.2    Malenka, R.C.3    England, P.M.4    Mechanism, B.A.5
  • 6
    • 34547556737 scopus 로고    scopus 로고
    • Rapid synthesis and synaptic insertion of GluR2 for mGluR-LTD in the ventral tegmental area
    • Mameli, M., Balland, B., Lujan, R. & Luscher, C. Rapid synthesis and synaptic insertion of GluR2 for mGluR-LTD in the ventral tegmental area. Science 317, 530-533 (2007).
    • (2007) Science , vol.317 , pp. 530-533
    • Mameli, M.1    Balland, B.2    Lujan, R.3    Luscher, C.4
  • 7
    • 57849098746 scopus 로고    scopus 로고
    • Long-lasting modulation of glutamatergic transmission in VTA dopamine neurons after a single dose of benzodiazepine agonists
    • Heikkinen, A. E., Moykkynen, T. P. & Korpi, E. R. Long-lasting modulation of glutamatergic transmission in VTA dopamine neurons after a single dose of benzodiazepine agonists. Neuropsychopharmacol. 34, 290-298 (2009).
    • (2009) Neuropsychopharmacol. , vol.34 , pp. 290-298
    • Heikkinen, A.E.1    Moykkynen, T.P.2    Korpi, E.R.3
  • 8
    • 0026689870 scopus 로고
    • Two types of neurone in the rat ventral tegmental area and their synaptic inputs
    • Johnson, S. W. & North, R. A. Two types of neurone in the rat ventral tegmental area and their synaptic inputs. J. Physiol. (Lond.) 450, 455-468 (1992).
    • (1992) J. Physiol. (Lond.) , vol.450 , pp. 455-468
    • Johnson, S.W.1    North, R.A.2
  • 9
    • 0032407484 scopus 로고    scopus 로고
    • A receptors: Relative orientation of ligands and amino acid side chains
    • A receptors: relative orientation of ligands and amino acid side chains. Mol. Pharmacol. 54, 1097-1105 (1998).
    • (1998) Mol. Pharmacol. , vol.54 , pp. 1097-1105
    • Sigel, E.1    Schaerer, M.T.2    Buhr, A.3    Baur, R.4
  • 10
    • 0028977843 scopus 로고
    • GABAA-receptor heterogeneity in the adult rat brain: Differential regional and cellular distribution of seven major subunits
    • Fritschy, J. M. & Mohler, H. GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits. J. Comp. Neurol. 359, 154-194 (1995).
    • (1995) J. Comp. Neurol. , vol.359 , pp. 154-194
    • Fritschy, J.M.1    Mohler, H.2
  • 11
    • 1842562921 scopus 로고    scopus 로고
    • Identification of GABAA receptor subunit variants in midbrain dopaminergic neurons
    • Okada, H., Matsushita, N., Kobayashi, K. & Kobayashi, K. Identification of GABAA receptor subunit variants in midbrain dopaminergic neurons. J. Neurochem. 89, 7-14 (2004).
    • (2004) J. Neurochem. , vol.89 , pp. 7-14
    • Okada, H.1    Matsushita, N.2    Kobayashi, K.3    Kobayashi, K.4
  • 13
    • 0033592682 scopus 로고    scopus 로고
    • A receptor subtypes
    • A receptor subtypes. Nature 401, 796-800 (1999).
    • (1999) Nature , vol.401 , pp. 796-800
    • Rudolph, U.1
  • 14
    • 0026438363 scopus 로고
    • GABAA-receptor subtypes differing in a-subunit composition display unique pharmacological properties
    • Möhler, H., Benke, D., Mertens, S. & Fritschy, J. M. GABAA-receptor subtypes differing in a-subunit composition display unique pharmacological properties. Adv. Biochem. Psychopharmacol. 47, 41-53 (1992).
    • (1992) Adv. Biochem. Psychopharmacol. , vol.47 , pp. 41-53
    • Möhler, H.1    Benke, D.2    Mertens, S.3    Fritschy, J.M.4
  • 15
    • 0034108997 scopus 로고    scopus 로고
    • A receptor alpha1 subtype
    • A receptor alpha1 subtype. Nature Neurosci. 3, 587-592 (2000).
    • (2000) Nature Neurosci. , vol.3 , pp. 587-592
    • McKernan, R.M.1
  • 16
    • 0031029463 scopus 로고    scopus 로고
    • A subset of ventral tegmental area neurons is inhibited by dopamine, 5-hydroxytryptamine and opioids
    • Cameron, D. L., Wessendorf, M. W. & Williams, J. T. A subset of ventral tegmental area neurons is inhibited by dopamine, 5-hydroxytryptamine and opioids. Neuroscience 77, 155-166 (1997).
    • (1997) Neuroscience , vol.77 , pp. 155-166
    • Cameron, D.L.1    Wessendorf, M.W.2    Williams, J.T.3
  • 17
    • 33845305449 scopus 로고    scopus 로고
    • The ventral tegmental area revisited: Is there an electrophysiological marker for dopaminergic neurons?
    • Margolis, E. B., Lock, H., Hjelmstad, G. O. & Fields, H. L. The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons? J. Physiol. (Lond.) 577, 907-924 (2006).
    • (2006) J. Physiol. (Lond.) , vol.577 , pp. 907-924
    • Margolis, E.B.1    Lock, H.2    Hjelmstad, G.O.3    Fields, H.L.4
  • 18
    • 0031919845 scopus 로고    scopus 로고
    • Development of excitatory circuitry in the hippocampus
    • Hsia, A. Y., Malenka, R. C. & Nicoll, R. A. Development of excitatory circuitry in the hippocampus. J. Neurophysiol. 79, 2013-2024 (1998).
    • (1998) J. Neurophysiol. , vol.79 , pp. 2013-2024
    • Hsia, A.Y.1    Malenka, R.C.2    Nicoll, R.A.3
  • 20
    • 67649806794 scopus 로고    scopus 로고
    • 21 influx and glutamate release
    • 21 influx and glutamate release. J. Biol. Chem. 284, 8726-8737 (2009).
    • (2009) J. Biol. Chem. , vol.284 , pp. 8726-8737
    • Long, P.1
  • 22
    • 28044453713 scopus 로고    scopus 로고
    • A receptors to a dopamine hyperfunction
    • A receptors to a dopamine hyperfunction. Proc. Natl Acad. Sci. USA 102, 17154-17159 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 17154-17159
    • Yee, B.K.1
  • 23
    • 0034613173 scopus 로고    scopus 로고
    • Molecular and neuronal substrate for the selective attenuation of anxiety
    • Löw, K., et al. Molecular and neuronal substrate for the selective attenuation of anxiety. Science 290, 131-134 (2000).
    • (2000) Science , vol.290 , pp. 131-134
    • Löw, K.1
  • 24
    • 4444249161 scopus 로고    scopus 로고
    • Firing properties of dopamine neurons in freely moving dopamine-deficient mice: Effects of dopamine receptor activation and anesthesia
    • Robinson, S., Smith, D. M., Mizumori, S. J. & Palmiter, R. D. Firing properties of dopamine neurons in freely moving dopamine-deficient mice: effects of dopamine receptor activation and anesthesia. Proc. Natl Acad. Sci. USA 101, 13329-13334 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 13329-13334
    • Robinson, S.1    Smith, D.M.2    Mizumori, S.J.3    Palmiter, R.D.4
  • 25
    • 0036774104 scopus 로고    scopus 로고
    • Firing modes of midbrain dopamine cells in the freely moving rat
    • Hyland, B. I., Reynolds, J. N., Hay, J., Perk, C. G. & Miller, R. Firing modes of midbrain dopamine cells in the freely moving rat. Neuroscience 114, 475-492 (2002).
    • (2002) Neuroscience , vol.114 , pp. 475-492
    • Hyland, B.I.1    Reynolds, J.N.2    Hay, J.3    Perk, C.G.4    Miller, R.5
  • 26
    • 0021232872 scopus 로고
    • Self-injection of diazepam in naive rats: Effects of dose, schedule and blockade of different receptors
    • Pilotto, R., Singer, G. & Overstreet, D. Self-injection of diazepam in naive rats: effects of dose, schedule and blockade of different receptors. Psychopharmacology (Berl.) 84, 174-177 (1984).
    • (1984) Psychopharmacology (Berl.) , vol.84 , pp. 174-177
    • Pilotto, R.1    Singer, G.2    Overstreet, D.3
  • 27
    • 0021691721 scopus 로고
    • The influence of haloperidol and aminooxyacetic acid on etonitazene, alcohol, diazepam and barbital consumption
    • Fuchs, V., Burbes, E. & Coper, H. The influence of haloperidol and aminooxyacetic acid on etonitazene, alcohol, diazepam and barbital consumption. Drug Alcohol Depend. 14, 179-186 (1984).
    • (1984) Drug Alcohol Depend. , vol.14 , pp. 179-186
    • Fuchs, V.1    Burbes, E.2    Coper, H.3
  • 28
    • 0028839001 scopus 로고
    • Benzodiazepines appetite, and taste palatability
    • Berridge, K. C. & Pecina, S. Benzodiazepines, appetite, and taste palatability. Neurosci. Biobehav. Rev. 19, 121-131 (1995).
    • (1995) Neurosci. Biobehav. Rev. , vol.19 , pp. 121-131
    • Berridge, K.C.1    Pecina, S.2
  • 29
    • 0024363937 scopus 로고
    • Novel benzodiazepine receptor ligands: Palatable food intake following zolpidem, CGS 17867A, or Ro23-0364, in the rat
    • Yerbury, R. E. & Cooper, S. J. Novel benzodiazepine receptor ligands: palatable food intake following zolpidem, CGS 17867A, or Ro23-0364, in the rat. Pharmacol. Biochem. Behav. 33, 303-307 (1989).
    • (1989) Pharmacol. Biochem. Behav. , vol.33 , pp. 303-307
    • Yerbury, R.E.1    Cooper, S.J.2
  • 31
    • 0025346635 scopus 로고
    • Modulation of A10 dopamine neurons by c-aminobutyric acid agonists
    • Kalivas, P. W., Duffy, P. & Eberhardt, H. Modulation of A10 dopamine neurons by c-aminobutyric acid agonists. J. Pharmacol. Exp. Ther. 253, 858-866 (1990).
    • (1990) J. Pharmacol. Exp. Ther. , vol.253 , pp. 858-866
    • Kalivas, P.W.1    Duffy, P.2    Eberhardt, H.3
  • 32
    • 0032490594 scopus 로고    scopus 로고
    • A receptors-an in vivo electrochemical study
    • A receptors-an in vivo electrochemical study. Brain Res. 798, 156-165 (1998).
    • (1998) Brain Res. , vol.798 , pp. 156-165
    • Xi, Z.X.1    Stein, E.A.2
  • 33
    • 33847612861 scopus 로고    scopus 로고
    • B receptors in the regulation of the nucleus accumbens dopamine response to stress
    • B receptors in the regulation of the nucleus accumbens dopamine response to stress. Brain Res. 1150, 62-68 (2007).
    • (2007) Brain Res. , vol.1150 , pp. 62-68
    • Doherty, M.1    Gratton, A.2
  • 34
    • 0018604205 scopus 로고
    • Paradoxical GABA excitation of nigral dopaminergic cells: Indirect mediation through reticulata inhibitory neurons
    • Grace, A. A. & Bunney, B. S. Paradoxical GABA excitation of nigral dopaminergic cells: indirect mediation through reticulata inhibitory neurons. Eur. J. Pharmacol. 59, 211-218 (1979).
    • (1979) Eur. J. Pharmacol. , vol.59 , pp. 211-218
    • Grace, A.A.1    Bunney, B.S.2
  • 35
    • 0026652547 scopus 로고
    • Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: An in vivo microdialysis study
    • Klitenick, M. A., DeWitte, P. & Kalivas, P. W. Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study. J. Neurosci. 12, 2623-2632 (1992).
    • (1992) J. Neurosci. , vol.12 , pp. 2623-2632
    • Klitenick, M.A.1    Dewitte, P.2    Kalivas, P.W.3
  • 36
    • 0033902630 scopus 로고    scopus 로고
    • Epidemiological evidence for a low abuse potential of zolpidem
    • Soyka, M., Bottlender, R. & Moller, H. J. Epidemiological evidence for a low abuse potential of zolpidem. Pharmacopsychiatry 33, 138-141 (2000).
    • (2000) Pharmacopsychiatry , vol.33 , pp. 138-141
    • Soyka, M.1    Bottlender, R.2    Moller, H.J.3
  • 37
    • 14144254686 scopus 로고    scopus 로고
    • Different GABAA receptor subtypes mediate the anxiolytic, abuse-related, and motor effects of benzodiazepine-like drugs in primates
    • Rowlett, J. K., Platt, D. M., Lelas, S., Atack, J. R. & Dawson, G. R. Different GABAA receptor subtypes mediate the anxiolytic, abuse-related, and motor effects of benzodiazepine-like drugs in primates. Proc. Natl Acad. Sci. USA 102, 915-920 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 915-920
    • Rowlett, J.K.1    Platt, D.M.2    Lelas, S.3    Atack, J.R.4    Dawson, G.R.5
  • 39
    • 70449628050 scopus 로고    scopus 로고
    • Dynamics of neuronal circuits in addiction: Reward, antireward, and emotional memory
    • Koob, G. F. Dynamics of neuronal circuits in addiction: reward, antireward, and emotional memory. Pharmacopsychiatry 42 (suppl. 1), S32-S41 (2009).
    • (2009) Pharmacopsychiatry , vol.42 , Issue.SUPPL. 1
    • Koob, G.F.1
  • 40
    • 46049083775 scopus 로고    scopus 로고
    • Cocaine-evoked synaptic plasticity: A key to addiction?
    • Lüscher, C. & Bellone, C. Cocaine-evoked synaptic plasticity: a key to addiction? Nature Neurosci. 11, 737-738 (2008).
    • (2008) Nature Neurosci. , vol.11 , pp. 737-738
    • Lüscher, C.1    Bellone, C.2
  • 41
    • 68149148934 scopus 로고    scopus 로고
    • Cocaine-evoked synaptic plasticity: Persistence in the VTA triggers adaptations in the NAc
    • Mameli, M., et al. Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc. Nature Neurosci. 12, 1036-1041 (2009).
    • (2009) Nature Neurosci. , vol.12 , pp. 1036-1041
    • Mameli, M.1
  • 42
    • 48349092693 scopus 로고    scopus 로고
    • A unified framework for addiction: Vulnerabilities in the decision process
    • Redish, A. D., Jensen, S. & Johnson, A. A unified framework for addiction: vulnerabilities in the decision process. Behav. Brain Sci. 31, 415-437 (2008).
    • (2008) Behav. Brain Sci. , vol.31 , pp. 415-437
    • Redish, A.D.1    Jensen, S.2    Johnson, A.3
  • 43
    • 36448957260 scopus 로고    scopus 로고
    • B receptors and GIRK channels in dopamine neurons of the ventral tegmental area
    • B receptors and GIRK channels in dopamine neurons of the ventral tegmental area. Nature Neurosci. 10, 1559-1568 (2007).
    • (2007) Nature Neurosci. , vol.10 , pp. 1559-1568
    • Labouèbe, G.1
  • 44
    • 12144286982 scopus 로고    scopus 로고
    • Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons
    • Zhao, S., et al. Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons. Eur. J. Neurosci. 19, 1133-1140 (2004).
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1133-1140
    • Zhao, S.1
  • 45
    • 0242300262 scopus 로고    scopus 로고
    • Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse
    • Tamamaki, N., et al. Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse. J. Comp. Neurol. 467, 60-79 (2003).
    • (2003) J. Comp. Neurol. , vol.467 , pp. 60-79
    • Tamamaki, N.1
  • 47
    • 0020558538 scopus 로고
    • Intracellular and extracellular electrophysiology of nigral dopaminergic neurons-1. Identification and characterization
    • Grace, A. A. & Bunney, B. S. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons-1. Identification and characterization. Neuroscience 10, 301-315 (1983).
    • (1983) Neuroscience , vol.10 , pp. 301-315
    • Grace, A.A.1    Bunney, B.S.2
  • 48
    • 1642404961 scopus 로고    scopus 로고
    • Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli
    • Ungless, M. A., Magill, P. J. & Bolam, J. P. Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli. Science 303, 2040-2042 (2004).
    • (2004) Science , vol.303 , pp. 2040-2042
    • Ungless, M.A.1    Magill, P.J.2    Bolam, J.P.3


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