Pulmonary and atherogenic effects of Multi-Walled Carbon Nanotubes (MWCNT) in Apolipoprotein-E-deficient mice

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 78, Issue 4, 2015, Pages 244-253

  Han, Sung Gu ^a   Howatt, Deborah ^b   Daugherty, Alan ^b   Gairola, Gary ^b  

^a Konkuk University   (South Korea)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; LACTATE DEHYDROGENASE; MUCIN; MULTI WALLED NANOTUBE; SURFACTANT PROTEIN D; CARBON NANOTUBE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA INTIMA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CARDIOVASCULAR EFFECT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; LUNG; LUNG INJURY; LUNG LAVAGE; LUNG TOXICITY; MOUSE; MOUSE MODEL; NANOTOXICOLOGY; NASOPHARYNGEAL ASPIRATION; NEUTROPHIL; NONHUMAN; PARTICLE SIZE; PNEUMONIA; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; SURFACE PROPERTY; ANIMAL; BLOOD; CARDIOVASCULAR SYSTEM; CHEMICALLY INDUCED; CHEMISTRY; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; EXPOSURE; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; TOXICITY TESTING;

ANIMALIA; MUS;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BRONCHOALVEOLAR LAVAGE FLUID; CARDIOVASCULAR SYSTEM; CHOLESTEROL; DISEASE MODELS, ANIMAL; FEMALE; INHALATION EXPOSURE; L-LACTATE DEHYDROGENASE; LUNG; MICE; MICE, KNOCKOUT; MUCINS; NANOTUBES, CARBON; NEUTROPHILS; PNEUMONIA; PULMONARY SURFACTANT-ASSOCIATED PROTEIN D; TOXICITY TESTS, SUBCHRONIC;

EID: 84923338231     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287394.2014.958421     Document Type: Article

References (50)

1. Almeida, S. M., A. V. Silva, and S. Sarmento. 2014. Effects of exposure to particles and ozone on hospital admissions for cardiorespiratory diseases in SetuBal, Portugal. J. Toxicol. Environ. Health A 77:837-848
2. Andrews, R., D. Jacques, A. M. Rao, F. Derbyshire, D. Qian, X. Fan, E. C. Dickey, and J. Chen. 1999. Continuous production of aligned carbon nanotubes: A step closer to commercial realization. Chem. Phys. Lett. 303: 467-474
3. Araujo, J. A., B. Barajas, M. Kleinman, X. Wang, B. J. Bennett, K. W. Gong, M. Navab, J. Harkema, C. Sioutas, A. J. Lusis, and A. E. Nel. 2008. Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress. Circ. Res. 102: 589-596
4. Arnal, J. F., P. Y. Scarabin, F. Tremollieres, H. Laurell, and P. Gourdy. 2007. Estrogens in vascular biology and disease: where do we stand today?. Curr. Opin. Lipidol. 18:554-560
5. Boczkowski, J., and S. Lanone. 2012. Respiratory toxicities of nanomaterials- A focus on carbon nanotubes. Adv. Drug Deliv. Rev. 64: 1694-1699
6. Brocato, J., H. Sun, M. Shamy, T. Kluz, M. A. Alghamdi, M. I. Khoder, L. C. Chen, and M. Costa. 2014. Particulate matter from Saudi Arabia induces genes involved in inflammation, metabolic syndrome and atherosclerosis. J. Toxicol. Environ. Health A 77: 751-766
7. Campen, M. J., A. Lund, and M. Rosenfeld. 2012. Mechanisms linking traffic-related air pollution and atherosclerosis. Curr. Opin. Pulmon. Med. 18: 155-160
8. Chen, L. C., C. Quan, J. S. Hwang, X. Jin, Q. Li, M. Zhong, S. Rajagopalan, and Q. Sun. 2010. Atherosclerosis lesion progression during inhalation exposure to environmental tobacco smoke: A comparison to concentrated ambient air fine particles exposure. Inhal. Toxicol. 22: 449-459
9. Chiba, T., M. Ikeda, K. Umegaki, and T. Tomita. 2011. Estrogen-dependent activation of neutral cholesterol ester hydrolase underlying gender difference of atherogenesis in apoE-/- mice. Atherosclerosis. 219:545-551
10. Chiu, H. F., C. C. Chang, and C. Y. Yang. 2014. Relationship between hemorrhagic stroke hospitalization and exposure to fine particulate air pollution in Taipei, Taiwan. J. Toxicol. Environ. Health A 77:1154-1163
11. Daugherty, A., and D. L. Rateri. 2005. Development of experimental designs for atherosclerosis studies in mice. Methods 36: 129-138
12. De Volder, M. F., S. H. Tawfick, R. H. Baughman, and A. J. Hart. 2013. Carbon nanotubes: Present and future commercial applications. Science 339: 535-539
13. Erdely, A., T. Hulderman, R. Salmen, A. Liston, P. C. Zeidler-Erdely, D. Schwegler-Berry, V. Castranova, S. Koyama, Y. A. Kim, M. Endo, and P. P. Simeonova. 2009. Cross-Talk between lung and systemic circulation during carbon nanotube respiratory exposure. Potential biomarkers. Nano Lett. 9: 36-43
14. Fenoglio, I., G. Greco, M. Tomatis, J. Muller, E. Raymundo-Pinero, F. Beguin, A. Fonseca, J. B. Nagy, D. Lison, and B. Fubini. 2008. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: physicochemical aspects. Chem. Res. Toxicol. 21: 1690-1697
15. Gairola, C. G., M. L. Drawdy, A. E. Block, and A. Daugherty. 2001. Sidestream cigarette smoke accelerates atherogenesis in apolipoprotein E-/- mice. Atherosclerosis 156:49-55
16. Gwinn, M. R., and V. Vallyathan. 2006. Nanoparticles: health effects-Pros and cons. Environ. Health Perspect. 114: 1818-1825
17. Han, S. G. 2014. Pulmonary response of mice to a sequential exposure of side-stream cigarette smoke and multi-walled carbon nanotubes. Inhal. Toxicol. 26: 327-332
18. Han, S. G., R. Andrews, and C. G. Gairola. 2010. Acute pulmonary response of mice to multi-wall carbon nanotubes. Inhal. Toxicol. 22: 340-347
19. Han, S. G., R. Andrews, C. G. Gairola, and D. K. Bhalla. 2008. Acute pulmonary effects of combined exposure to carbon nanotubes and ozone in mice. Inhal. Toxicol. 20: 391-398
20. Jacobsen, N. R., P. Moller, K. A. Jensen, U. Vogel, O. Ladefoged, S. Loft, and H. Wallin. 2009. Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice. Part. Fibre Toxicol. 6: 2
21. Johnston, H. J., G. R. Hutchison, F. M. Christensen, S. Peters, S. Hankin, K. Aschberger, and V. Stone. 2010. A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physicochemical characteristics. Nanotoxicology 4: 207-246
22. Kendall, M., and S. Holgate. 2012. Health impact and toxicological effects of nanomaterials in the lung. Respirology 17: 743-758
23. Kreyling, W. G., M. Semmler-Behnke, J. Seitz, W. Scymczak, A. Wenk, P. Mayer, S. Takenaka, and G. Oberdorster. 2009. Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs. Inhal. Toxicol. 21(suppl 1): 55-60
24. Lee, J. H., S. B. Lee, G. N. Bae, K. S. Jeon, J. U. Yoon, J. H. Ji, J. H. Sung, B. G. Lee, J. H. Lee, J. S. Yang, H. Y. Kim, C. S. Kang, and I. J. Yu. 2010. Exposure assessment of carbon nanotube manufacturing workplaces. Inhal. Toxicol. 22:369-381
25. Li, R., X. Wang, Z. Ji, B. Sun, H. Zhang, C. H. Chang, S. Lin, H. Meng, Y. P. Liao, M. Wang, Z. Li, A. A. Hwang, T. B. Song, R. Xu, Y. Yang, J. I. Zink, A. E. Nel, and T. Xia. 2013. Surface charge and cellular processing of covalently functionalized multiwall carbon nanotubes determine pulmonary toxicity. ACS Nano. 7:2352-2368
26. Li, Z., T. Hulderman, R. Salmen, R. Chapman, S. S. Leonard, S. H. Young, A. Shvedova, M. I. Luster, and P. P. Simeonova. 2007. Cardiovascular effects of pulmonary exposure to single-wall carbon nanotubes. Environ. Health Perspect. 115:377-382
27. Ma-Hock, L., S. Treumann, V. Strauss, S. Brill, F. Luizi, M. Mertler, K. Wiench, A. O. Gamer, B. van Ravenzwaay, and R. Landsiedel. 2009. Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months. Toxicol. Sci. 112: 468-481
28. McIntyre, R. A. 2012. Common nano-materials and their use in real world applications. Sci. Prog. 95: 1-22
29. Mendelsohn, M. 2008. Hormones and cardiovascular disease. Gynecol. Endocrinol. 24: 483-484
30. Meyrelles, S. S., V. A. Peotta, T. M. Pereira, and E. C. Vasquez. 2011. Endothelial dysfunction in the apolipoprotein E-deficient mouse: Insights into the influence of diet, gender and aging. Lipids Health Dis. 10: 211
31. Moller, P., L. Mikkelsen, L. K. Vesterdal, J. K. Folkmann, L. Forchhammer, M. Roursgaard, P. H. Danielsen, and S. Loft. 2011. Hazard identification of particulate matter on vasomotor dysfunction and progression of atherosclerosis. Crit. Rev. Toxicol. 41: 339-368
32. Muhlfeld, C., C. A. Poland, R. Duffin, C. Brandenberger, F. A. Murphy, B. Rothen-Rutishauser, P. Gehr, and K. Donaldson. 2012. Differential effects of long and short carbon nanotubes on the gas-exchange region of the mouse lung. Nanotoxicology 6: 867-879
33. Nemmar, A., M. F. Hoylaerts, P. H. Hoet, J. Vermylen, and B. Nemery. 2003. Size effect of intratracheally instilled particles on pulmonary inflammation and vascular thrombosis. Toxicol. Appl. Pharmacol. 186: 38-45
34. Niwa, Y., Hiura, Y., Murayama, T., Yokode, M., and Iwai, N. 2007. Nano-sized carbon black exposure exacerbates atherosclerosis in LDL-receptor knockout mice. Circ. J. 71: 1157-1161
35. Park, E. J., J. Roh, S. N. Kim, M. S. Kang, B. S. Lee, Y. Kim, and S. Choi. 2011. Biological toxicity and inflammatory response of semisingle-walled carbon nanotubes. PLoS One 6: e25892
36. Pastva, A. M., J. R. Wright, and K. L. Williams. 2007. Immunomodulatory roles of surfactant proteins A and D: implications in lung disease. Proc. Am. Thorac. Soc. 4: 252-257
37. Porter, D. W., Hubbs, A. F., Mercer, R. R., Wu, N., Wolfarth, M. G., Sriram, K., Leonard, S., Battelli, L., Schwegler-Berry, D., Friend, S., Andrew, M., Chen, B. T., Tsuruoka, S., Endo, M., and Castranova, V. 2010. Mouse pulmonary dose- And time course-responses induced by exposure to multi-walled carbon nanotubes. Toxicology. 269: 136-147
38. Quan, C., Q. Sun, M. Lippmann, and L. C. Chen. 2010. Comparative effects of inhaled diesel exhaust and ambient fine particles on inflammation, atherosclerosis, and vascular dysfunction. Inhal. Toxicol. 22: 738-753
39. Sager, T. M., M. W. Wolfarth, M. Andrew, A. Hubbs, S. Friend, T. H. Chen, D. W. Porter, N.Wu, F. Yang, R. F. Hamilton, and A. Holian. 2014. Effect of multi-walled carbon nanotube surface modification on bioactivity in the C57BL/6 mouse model. Nanotoxicology 8: 317-327
40. Shimada, A., N. Kawamura, M. Okajima, T. Kaewamatawong, H. Inoue, and T. Morita. 2006. Translocation pathway of the intratracheally instilled ultrafine particles from the lung into the blood circulation in the mouse. Toxicol. Pathol. 34: 949-957
41. Shvedova, A. A., E. R. Kisin, R. Mercer, A. R. Murray, V. J. Johnson, A. I. Potapovich, Y. Y. Tyurina, O. Gorelik, S. Arepalli, D. Schwegler-Berry, A. F. Hubbs, J. Antonini, D. E. Evans, B. K. Ku, D. Ramsey, A. Maynard, V. E. Kagan, V. Castranova, and P. Baron. 2005. Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am. J. Physiol. Lung Cell Mol. Physiol. 289: L698-L708
42. Simkhovich, B. Z., M. T. Kleinman, and R. A. Kloner. 2008. Air pollution and cardiovascular injury epidemiology, toxicology, and mechanisms. J. Am. Coll. Cardiol. 52: 719-726
43. Terzano, C., F. Di Stefano, V. Conti, E. Graziani, and A. Petroianni. 2010. Air pollution ultrafine particles: toxicity beyond the lung. Eur. Rev. Med. Pharmacol. Sci. 14: 809-821
44. Valavanidis, A., K. Fiotakis, and T. Vlachogianni. 2008. Airborne particulate matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic mechanisms. J. Environ. Sci. Health C Environ. Carcinogen. Ecotoxicol. Rev. 26: 339-362
45. Vesterdal, L. K., J. K. Folkmann, N. R. Jacobsen, M. Sheykhzade, H. Wallin, S. Loft, and P. Moller. 2010. Pulmonary exposure to carbon black nanoparticles and vascular effects. Part Fibre Toxicol. 7: 33
46. Villablanca, A. C., M. Jayachandran, and C. Banka. 2010. Atherosclerosis and sex hormones: current concepts. Clin. Sci. (London) 119: 493-513
47. Voynow, J. A., S. J. Gendler, and M. C. Rose. 2006. Regulation of mucin genes in chronic inflammatory airway diseases. Am. J. Respir. Cell Mol. Biol. 34: 661-665
48. Wang, X., P. Katwa, R. Podila, P. Chen, P. C. Ke, A. M. Rao, D. M. Walters, C. J. Wingard, and J. M. Brown. 2011. Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice. Part. Fibre Toxicol. 8:24
49. Ying, Z., T. Kampfrath, G. Thurston, B. Farrar, M. Lippmann, A. Wang, Q. Sun, L. C. Chen, and S. Rajagopalan. 2009. Ambient particulates alter vascular function through induction of reactive oxygen and nitrogen species. Toxicol. Sci. 111: 80-88
50. Zhao, J., and V. Castranova. 2011. Toxicology of nanomaterials used in nanomedicine. J Toxicol. Environ Health B 14: 593-632