Conformational flexibility and changes underlying activation of the SUMO-specific protease SENP1 by remote substrate binding

Nature Communications

Volumn 5, Issue , 2014, Pages

  Chen, Chih Hong ^a   Namanja, Andrew T ^a   Chen, Yuan ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SENP1 PROTEIN; SUMO PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; PEPTIDE; PROTEIN BINDING; PROTEINASE; SENP1 PROTEIN, HUMAN;

CATALYSIS; ENZYME ACTIVITY; EUKARYOTE; GERM CELL; SUBSTRATE;

ALLOSTERISM; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; RECOGNITION; BINDING SITE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ESCHERICHIA COLI; HUMAN; KINETICS; METABOLISM; NEOPLASM; PERMEABILITY; PROTEIN ANALYSIS; PROTEIN SECONDARY STRUCTURE;

EUKARYOTA;

ALLOSTERIC SITE; CATALYTIC DOMAIN; ENDOPEPTIDASES; ESCHERICHIA COLI; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; NEOPLASMS; PEPTIDES; PERMEABILITY; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY; UBIQUITIN;

EID: 84923332311     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5968     Document Type: Article

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