Strategies for the identification of novel inhibitors of deubiquitinating enzymes

Biochemical Society Transactions

Volumn 36, Issue 5, 2008, Pages 828-832

  Goldenberg, Seth J ^a   McDermott, Jeffrey L ^a   Butt, Tauseef R ^a   Mattern, Michael R ^a   Nicholson, Benjamin ^a  

^a Progenra Inc   (United States)

Author keywords

deISGylase; deNEDDylase; deSUMOylase; Deubiquitinating enzyme (DUB); High throughput screening (HTS); Isopeptidase; Small ubiquitin related modifier (SUMO)

Indexed keywords

BORTEZOMIB; DEUBIQUITINATING ENZYME; DEUBIQUITINATING ENZYME INHIBITOR; ENZYME INHIBITOR; INTERFERON STIMULATED GENE FACTOR 15; NEDD8 PROTEIN; PHOSPHOLIPASE A2; PROTEASOME; PROTEIN MDM2; SUMO PROTEIN; TRANSCRIPTION FACTOR; UB SPECIFIC PROTEASE 7; UBIQUITIN; UNCLASSIFIED DRUG;

CONFERENCE PAPER; CONJUGATION; DRUG SCREENING; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE RESONANCE ENERGY TRANSFER; GEL ELECTROPHORESIS; HUMAN; INTERMETHOD COMPARISON; LIQUID SCINTILLATION COUNTING; NEOPLASM; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION;

BIOLOGICAL ASSAY; DISEASE; ENDOPEPTIDASES; ENZYME INHIBITORS; HUMANS; ISOENZYMES; PHOSPHOLIPASES A2; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITIN;

EID: 53849126497     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0360828     Document Type: Conference Paper

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