MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL

Nature Communications

Volumn 5, Issue , 2014, Pages

  Landon, Ari L ^a   Muniandy, Parameswary A ^a,b   Shetty, Amol C ^a   Lehrmann, Elin ^c   Volpon, Laurent ^d   Houng, Simone ^a,b   Zhang, Yongqing ^c   Dai, Bojie ^a,b   Peroutka, Raymond ^a   Mazan Mamczarz, Krystyna ^a   Steinhardt, James ^a   Mahurkar, Anup ^a   Becker, Kevin G ^c   Borden, Katherine L ^d   Gartenhaus, Ronald B ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b BALTIMORE VA MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; CYCLOHEXIMIDE; INITIATION FACTOR 4A; INITIATION FACTOR 4E; INITIATION FACTOR 4E1; INITIATION FACTOR 4F; INITIATION FACTOR 4G; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE INTERACTING KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INTERACTING KINASE 2; PHOSPHOPROTEIN PHOSPHATASE 2; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VX 702; EIF4E3 PROTEIN, HUMAN; MKNK1 PROTEIN, HUMAN; MKNK2 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE;

CANCER; CYTOLOGY; GENE EXPRESSION; INHIBITION; RNA;

ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVE SITE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LARGE CELL LYMPHOMA; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA STABILITY; RNA TRANSLATION; TRANSCRIPTION INITIATION; TRANSLATION INITIATION; ENZYMOLOGY; GENETICS; METABOLISM; PHOSPHORYLATION; PROTEIN SYNTHESIS; TUMOR CELL LINE;

CELL LINE, TUMOR; EUKARYOTIC INITIATION FACTOR-4E; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOMA, LARGE B-CELL, DIFFUSE; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER;

EID: 84923327681     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6413     Document Type: Article

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