Functional GIP receptors play a major role in islet compensatory response to high fat feeding in mice

Biochimica et Biophysica Acta - General Subjects

Volumn 1850, Issue 6, 2015, Pages 1206-1214

  Moffett, R Charlotte ^a   Vasu, Srividya ^a   Flatt, Peter R ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

Alpha cell; Gastric inhibitory polypeptide; Immunohistochemistry; K cell

Indexed keywords

GASTRIC INHIBITORY POLYPEPTIDE; GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; HORMONE RECEPTOR; INCRETIN; INCRETIN RECEPTOR; INSULIN; UNCLASSIFIED DRUG; GLUCAGON; GLUCOSE BLOOD LEVEL;

ADAPTIVE BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY FAT DISTRIBUTION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FAT INTAKE; GIPR GENE; GLUCAGON BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HORMONE BLOOD LEVEL; HORMONE PROTEIN COMPLEX; HYPERGLYCEMIA; HYPERINSULINEMIA; IMMUNOHISTOCHEMISTRY; INNER CELL MASS; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; KNOCKOUT MOUSE; LIPID DIET; MALE; MORPHOLOGICAL ADAPTATION; MOUSE; MOUSE MODEL; NONHUMAN; ORGAN SIZE; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREAS SECRETION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; ADAPTATION; ANIMAL; BLOOD; C57BL MOUSE; DEFICIENCY; GENETICS; INTESTINE; METABOLISM; OBESITY; PATHOLOGY; PATHOPHYSIOLOGY; TIME;

MUS;

ADAPTATION, PHYSIOLOGICAL; ADIPOSITY; ANIMALS; APOPTOSIS; BLOOD GLUCOSE; CELL PROLIFERATION; DIET, HIGH-FAT; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; INSULIN; INSULIN RESISTANCE; INTESTINES; ISLETS OF LANGERHANS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, GASTROINTESTINAL HORMONE; TIME FACTORS;

EID: 84923327279     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2015.02.006     Document Type: Article

References (43)

1. V.S. Malik, W.C. Willett, and F.B. Hu Global obesity: trends, risk factors and policy implications Nat. Rev. Endocrinol. 9 1 2013 13 27
2. D.A. Gapp, E.H. Leiter, D.L. Coleman, and R.W. Schwizer Temporal changes in pancreatic islet composition in C57BL/6J-db/db (diabetes) mice Diabetologia 25 5 1983 439 443
3. E.H. Leiter, D.L. Coleman, A.B. Eisenstein, and I. Strack Dietary control of pathogenesis in C57BL/KsJ db/db diabetes mice Metabolism 30 6 1981 554 562
4. J.C. Brown, and J.R. Dryburgh A gastric inhibitory polypeptide II. The complete amino acid sequence Can. J. Biochem. 49 1971 867 872
5. J.J. Meier, M.A. Nauck, W.E. Schmidt, and B. Gallwitz Gastric inhibitory polypeptide: the neglected incretin revisited Regul. Pept. 107 1-3 2002 1 13
6. J.J. Holst The physiology of glucagon-like peptide 1 Physiol. Rev. 87 4 2007 1409 1439
7. C.H. McIntosh, S. Widenmaier, and S.J. Kim Glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide; GIP) Vitam. Horm. 80 2009 409 471
8. D.J. Drucker The biology of incretin hormones Cell Metab. 3 3 2006 153 165
9. C.F. Deacon, and J.J. Holst Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety Expert. Opin. Pharmacother. 14 15 2013 2047 2058
10. B. Kreymann, G. Williams, M.A. Ghatei, and S.R. Bloom Glucagon-like peptide-1 7-36: a physiological incretin in man Lancet 2 8571 1987 1300 1304
11. M.A. Nauck Is glucagon-like peptide 1 an incretin hormone? Diabetologia 42 3 1999 373 379
12. N. Irwin, V. Gault, and P.R. Flatt Therapeutic potential of the original incretin hormone glucose-dependent insulinotropic polypeptide: diabetes, obesity, osteoporosis and Alzheimer's disease? Expert. Opin. Investig. Drugs 19 9 2010 1039 1048
13. M.Y. Donath, and R. Burcelin GLP-1 effects on islets: hormonal, neuronal, or paracrine? Diabetes Care 36 2 2013 S145 S148
14. R.C. Moffett, S. Vasu, B. Thorens, D.J. Drucker, and P.R. Flatt Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy PLoS One 9 6 2014 e96863
15. Y. Fujita, R.D. Wideman, A. Asadi, G.K. Yang, R. Baker, T. Webber, T. Zhang, R. Wang, Z. Ao, G.L. Warnock, Y.N. Kwok, and T.J. Kieffer Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion Gastroenterology 138 5 2010 1966 1975
16. R.D. Wideman, S.D. Covey, G.C. Webb, D.J. Drucker, and T.J. Kieffer A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice Diabetes 56 11 2007 2744 2752
17. A.M. Hansen, T.B. Bödvarsdottir, D.N. Nordestgaard, R.S. Heller, C.F. Gotfredsen, K. Maedler, J.J. Fels, J.J. Holst, and A.E. Karlsen Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus - an adaptive response to hyperglycaemia? Diabetologia 54 6 2011 1379 1387
18. P. Marchetti, R. Lupi, M. Bugliani, C.L. Kirkpatrick, G. Sebastiani, F.A. Grieco, S. Del Guerra, V. D'Aleo, S. Piro, L. Marselli, U. Boggi, F. Filipponi, L. Tinti, L. Salvini, C.B. Wollheim, F. Purrello, and F. Dotta A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets Diabetologia 55 12 2012 3262 3272
19. R. Ugleholdt, M.L. Poulsen, P.J. Holst, J.C. Irminger, C. Orskov, J. Pedersen, and M.M. Rosenkilde Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor J. Biol. Chem. 281 16 2006 11050 11057
20. S. Vasu, R.C. Moffett, B. Thorens, and Flatt Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress PLoS One 9 6 2014 e101005
21. P.R. Flatt, and C.J. Bailey Abnormal plasma glucose and insulin responses in heterozygous lean (ob/+) mice Diabetologia 20 1981 573 577
22. S.L. Johnston, D.M. Souter, B.J. Tolkamp, I.J. Gordon, A.W. Illius, I. Kyriazakis, and J.R. Speakman Intake compensates for resting metabolic rate variation in female C57BL/6J mice fed high-fat diets Obesity (Silver Spring) 15 3 2007 600 606
23. V.A. Gault, P.L. McClean, R.S. Cassidy, N. Irwin, and P.R. Flatt Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets Diabetologia 50 8 2007 1752 1762
24. S. Andrikopoulos, C.M. Massa, K. Aston-Mourney, A. Funkat, B.C. Fam, R.L. Hull, S.E. Kahn, and J. Proietto Differential effect of inbred mouse strain (C57BL/6, DBA/2, 129T2) on insulin secretory function in response to a high fat diet J. Endocrinol. 187 1 2005 45 53
25. C. Talchai, S. Xuan, H.V. Lin, L. Sussel, and D. Accili Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure Cell 150 6 2012 1223 1234
26. M. Van de Casteele, G. Leuckx, Y. Cai, Y. Yuchi, V. Coppens, S. De Groef, N. Van Gassen, L. Baeyens, Y. Heremans, C.V. Wright, and H. Heimberg Partial duct ligation: β-cell proliferation and beyond Diabetes 63 8 2014 2567 2577
27. M.S. Winzell, C. Magnusson, and B. Ahrén Temporal and dietary fat content-dependent islet adaptation to high-fat feeding-induced glucose intolerance in mice Metabolism 56 1 2007 122 128
28. N.M. Whalley, L.E. Pritchard, D.M. Smith, and A. White Processing of proglucagon to GLP-1 in pancreatic alpha cells: is this a paracrine mechanism enabling GLP-1 to act on beta cells? J. Endocrinol. 211 2011 99 106
29. T.J. O'Malley, G.E. Fava, Y. Zhang, V.A. Fonseca, and H. Wu Progressive change of intra-islet GLP-1 production during diabetes development Diabetes Metab. Res. Rev. 2014 10.1002/dmrr.2534 E-pub ahead of print
30. F. Preitner, M. Ibberson, I. Franklin, C. Binnert, M. Pende, A. Gjinovci, T. Hansotia, D.J. Drucker, C. Wollheim, R. Burcelin, and B. Thorens Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors J. Clin. Invest. 113 4 2004 635 645
31. N. Pamir, F.C. Lynn, A.M. Buchan, J. Ehses, S.A. Hinke, J.A. Pospisilik, K. Miyawaki, Y. Yamada, Y. Seino, C.H. McIntosh, and R.A. Pederson Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis Am. J. Physiol. Endocrinol. Metab. 284 5 2003 E931 E939
32. K. Miyawaki, Y. Yamada, N. Ban, Y. Ihara, K. Tsukiyama, H. Zhou, S. Fujimoto, A. Oku, K. Tsuda, S. Toyokuni, H. Hiai, W. Mizunoya, T. Fushiki, J.J. Holst, M. Makino, A. Tashita, Y. Kobara, Y. Tsubamoto, T. Jinnouchi, T. Jomori, and Y. Seino Inhibition of gastric inhibitory polypeptide signaling prevents obesity Nat. Med. 8 7 2002 738 742
33. D. Yabe, and Y. Seino Incretin actions beyond the pancreas: lessons from knockout mice Curr. Opin. Pharmacol. 13 2013 946 953
34. V.A. Gault, N. Irwin, B.D. Green, J.T. McCluskey, B. Greer, C.J. Bailey, P. Harriott, F.P. O'Harte, and P.R. Flatt Chemical ablation of gastric inhibitory polypeptide receptor action by daily (Pro3)GIP administration improves glucose tolerance and ameliorates insulin resistance and abnormalities of islet structure in obesity-related diabetes Diabetes 54 8 2005 2436 2446
35. N. Irwin, and P.R. Flatt Evidence for beneficial effects of compromised gastric inhibitory polypeptide action in obesity-related diabetes and possible therapeutic implications Diabetologia 52 9 2009 1724 1731
36. K.P. Hummel, D.L. Coleman, and P.W. Lane The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL-KsJ and C57BL-6J strains Biochem. Genet. 7 1 1972 1 13
37. H. Chen, X. Gu, Y. Liu, J. Wang, S.E. Wirt, R. Bottino, H. Schorle, J. Sage, and S.K. Kim PDGF signalling controls age-dependent proliferation in pancreatic β-cells Nature 478 7369 2011 349 355
38. F. Gribble The gut endocrine system as a coordinator of postprandial nutrient homoeostasis Proc. Nutr. Soc. 71 2012 456 462
39. T. Vilsbøll, H. Agersø, and T. Lauritsen The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects Regul. Pept. 137 2006 168 172
40. B. Omar, and B. Ahren Pleiotropic mechanisms for the glucose-lowering action of DPP-4 inhibitors Diabetes 63 7 2014 2196 2202
41. G.E. Lim, and P.L. Brubaker Glucagon-like peptide 1 secretion by the L-cell - the view from within Diabetes 55 2 2006 S70 S77
42. A. Trumper, K. Trumper, and D. Horsch Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells J. Endocrinol. 174 2002 233 2246
43. C.H. McIntosh, S. Widenmaier, and S.J. Kim Glucose-dependent insulinotropic polypeptide signaling in pancreatic β-cells and adipocytes J. Diabet. Investig. 3 2 2012 96 106