Peroxisome proliferator-activated receptor γ coactivator 1α and FoxO3A mediate chondroprotection by AMP-activated protein kinase

Arthritis and Rheumatology

Volumn 66, Issue 11, 2014, Pages 3073-3082

  Zhao, Xianling ^a   Petursson, Freyr ^a   Viollet, Benoit ^b   Lotz, Martin ^c   Terkeltaub, Robert ^a   Liu Bryan, Ru ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSERM   (France)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6,7 DIHYDRO 4 HYDROXY 3 (2' HYDROXY 1,1' BIPHENYL 4 YL) 6 OXOTHIENO[2,3 B]PYRIDINE 5 CARBONITRILE; BETA ACTIN; CATALASE; COLLAGENASE 3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA; INTERLEUKIN 1BETA; MANGANESE SUPEROXIDE DISMUTASE; MENADIONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PLASMID DNA; SMALL INTERFERING RNA; STROMELYSIN; SUPEROXIDE; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AMPK ALPHA1 SUBUNIT, MOUSE; AMPK ALPHA2 SUBUNIT, MOUSE; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, HUMAN; FOXO3 PROTEIN, MOUSE; PPARGC1A PROTEIN, HUMAN; PPARGC1A PROTEIN, MOUSE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; BONE DENSITOMETRY; CARTILAGE CELL; CHONDROPROTECTION; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KNEE INSTABILITY; KNEE MENISCUS; MOUSE; NONHUMAN; OSTEOARTHRITIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; AGING; ANIMAL; C57BL MOUSE; CELL CULTURE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SURGERY;

AGING; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CATALASE; CELLS, CULTURED; CHONDROCYTES; DISEASE MODELS, ANIMAL; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; MENISCI, TIBIAL; MICE; MICE, INBRED C57BL; OSTEOARTHRITIS; OXIDATIVE STRESS; RNA, SMALL INTERFERING; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84923278599     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38791     Document Type: Article

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