Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α

Arthritis and Rheumatism

Volumn 63, Issue 7, 2011, Pages 1928-1937

  Terkeltaub, Robert ^a   Yang, Bing ^a   Lotz, Martin ^b   Liu Bryan, Ru ^a  

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 10; COLLAGENASE 3; DIMETHYLMETHYLENE BLUE; DYE; GLYCOSAMINOGLYCAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE BETA1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE BETA2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE GAMMA 1; INTERLEUKIN 1BETA; INTERLEUKIN 8; NITRIC OXIDE; SMALL INTERFERING RNA; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARTILAGE; CARTILAGE CELL; CHEMICAL REACTION; ENZYME ACTIVITY; GRIESS REACTION; HOMEOSTASIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KNEE; MOUSE; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; WESTERN BLOTTING;

AMP-ACTIVATED PROTEIN KINASES; BLOTTING, WESTERN; CARTILAGE, ARTICULAR; CHONDROCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; KNEE JOINT; MATRIX METALLOPROTEINASES; OSTEOARTHRITIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79959831457     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.30333     Document Type: Article

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