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Volumn 22, Issue 2, 2015, Pages 85-91

Emerging diagnostic and therapeutic approaches in core binding factor acute myeloid leukaemia

Author keywords

acute myeloid leukaemia; core binding factor; minimal residual disease; targeting therapeutics

Indexed keywords

ANTINEOPLASTIC AGENT; CYTARABINE; DAUNORUBICIN; FLUDARABINE; GEMTUZUMAB OZOGAMICIN; ROMIDEPSIN; CORE BINDING FACTOR;

EID: 84923222538     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0000000000000124     Document Type: Review
Times cited : (33)

References (79)
  • 1
    • 81255170298 scopus 로고    scopus 로고
    • Diagnostic and prognostic value of cytogenetics in acute myeloid leukemia
    • Grimwade D, Mrózek K. Diagnostic and prognostic value of cytogenetics in acute myeloid leukemia. Hematol Oncol Clin North Am 2011; 25:1135-1161.
    • (2011) Hematol Oncol Clin North Am , vol.25 , pp. 1135-1161
    • Grimwade, D.1    Mrózek, K.2
  • 2
    • 84878372012 scopus 로고    scopus 로고
    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
    • Cancer Genome Atlas Research Network. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med 2013;368:2059-2074.
    • (2013) N Engl J Med , vol.368 , pp. 2059-2074
    • Cancer Genome Atlas Research Network1
  • 3
    • 77449159028 scopus 로고    scopus 로고
    • Diagnosis and management of acute myeloid leukemia in adults: Recommendations from an international expert panel, on behalf of the European LeukemiaNet
    • Döhner H, Estey EH, Amadori S, et al. Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood 2010; 115:453-474.
    • (2010) Blood , vol.115 , pp. 453-474
    • Döhner, H.1    Estey, E.H.2    Amadori, S.3
  • 4
    • 84871774636 scopus 로고    scopus 로고
    • Prognostic significance of the European leukemia net standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia
    • Mrozek K, Marcucci G, Nicolet D, et al. Prognostic significance of the European leukemia net standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia. J Clin Oncol 2012; 30:4515-4523.
    • (2012) J Clin Oncol , vol.30 , pp. 4515-4523
    • Mrozek, K.1    Marcucci, G.2    Nicolet, D.3
  • 6
    • 80052366564 scopus 로고    scopus 로고
    • Molecular pathogenesis of core binding factor leukemia: Current knowledge and future prospects
    • Goyama S, Mulloy JC. Molecular pathogenesis of core binding factor leukemia: current knowledge and future prospects. Int J Hematol 2011; 94:126-133.
    • (2011) Int J Hematol , vol.94 , pp. 126-133
    • Goyama, S.1    Mulloy, J.C.2
  • 7
    • 24944464648 scopus 로고    scopus 로고
    • Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): A Cancer and Leukemia Group B study
    • Marcucci G, Mrozek K, Ruppert AS, et al. Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study. J Clin Oncol 2005; 23:5705-5717.
    • (2005) J Clin Oncol , vol.23 , pp. 5705-5717
    • Marcucci, G.1    Mrozek, K.2    Ruppert, A.S.3
  • 8
    • 33748747555 scopus 로고    scopus 로고
    • The clinical spectrum of adult acute myeloid leukaemia associated with core binding factor translocations
    • Appelbaum FR, Kopecky KJ, Tallman MS, et al. The clinical spectrum of adult acute myeloid leukaemia associated with core binding factor translocations. Br J Haematol 2006; 135:165-173.
    • (2006) Br J Haematol , vol.135 , pp. 165-173
    • Appelbaum, F.R.1    Kopecky, K.J.2    Tallman, M.S.3
  • 9
    • 4644288302 scopus 로고    scopus 로고
    • Individual patient data-based meta-analysis of patients aged 16 to 60 years with core binding factor acute myeloid leukemia: A survey of the German Acute Myeloid Leukemia Intergroup
    • Schlenk RF, Benner A, Krauter J, et al. Individual patient data-based meta-analysis of patients aged 16 to 60 years with core binding factor acute myeloid leukemia: a survey of the German Acute Myeloid Leukemia Intergroup. J Clin Oncol 2004; 22:3741-3750.
    • (2004) J Clin Oncol , vol.22 , pp. 3741-3750
    • Schlenk, R.F.1    Benner, A.2    Krauter, J.3
  • 10
    • 82555173049 scopus 로고    scopus 로고
    • Core-binding factor acute myeloid leukemia
    • Sangle NA, Perkins SL. Core-binding factor acute myeloid leukemia. Arch Pathol Lab Med 2011; 135:1504-1509.
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 1504-1509
    • Sangle, N.A.1    Perkins, S.L.2
  • 11
    • 0031025416 scopus 로고    scopus 로고
    • Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene
    • Yergeau DA, Hetherington CJ, Wang Q, et al. Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene. Nat Genet 1997; 15:303-306.
    • (1997) Nat Genet , vol.15 , pp. 303-306
    • Yergeau, D.A.1    Hetherington, C.J.2    Wang, Q.3
  • 12
    • 0032079424 scopus 로고    scopus 로고
    • Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors
    • Okuda T, Cai Z, Yang S, et al. Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors. Blood 1998; 91:3134-3143.
    • (1998) Blood , vol.91 , pp. 3134-3143
    • Okuda, T.1    Cai, Z.2    Yang, S.3
  • 13
    • 0032878921 scopus 로고    scopus 로고
    • The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia
    • Castilla LH, Garrett L, Adya N, et al. The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia. Nat Genet 1999; 23:144-146.
    • (1999) Nat Genet , vol.23 , pp. 144-146
    • Castilla, L.H.1    Garrett, L.2    Adya, N.3
  • 14
    • 84923227031 scopus 로고    scopus 로고
    • The increasing genomic complexity of acute myeloid leukemia
    • Rowe JM. The increasing genomic complexity of acute myeloid leukemia. Best Pract Res Clin Haematol 2014; 27:209-213.
    • (2014) Best Pract Res Clin Haematol , vol.27 , pp. 209-213
    • Rowe, J.M.1
  • 15
    • 77950480186 scopus 로고    scopus 로고
    • Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia
    • Liu S, Wu LC, Pang J, et al. Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia. Cancer Cell 2010; 17:333-347.
    • (2010) Cancer Cell , vol.17 , pp. 333-347
    • Liu, S.1    Wu, L.C.2    Pang, J.3
  • 16
    • 84872454123 scopus 로고    scopus 로고
    • Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway
    • Li Y, Gao L, Luo X, et al. Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway. Blood 2013; 121:499-509.
    • (2013) Blood , vol.121 , pp. 499-509
    • Li, Y.1    Gao, L.2    Luo, X.3
  • 17
    • 79952286086 scopus 로고    scopus 로고
    • C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice
    • Wang YY, Zhao LJ, Wu CF, et al. C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice. Proc Natl Acad Sci U S A 2011; 108:2450-2455.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 2450-2455
    • Wang, Y.Y.1    Zhao, L.J.2    Wu, C.F.3
  • 18
    • 84922393117 scopus 로고    scopus 로고
    • Core-binding factor acute myeloid leukemia: Heterogeneity, monitoring, and therapy
    • Solh M, Yohe S, Weisdorf D, et al. Core-binding factor acute myeloid leukemia: heterogeneity, monitoring, and therapy. Am J Hematol 2014;89:1121-1131.
    • (2014) Am J Hematol , vol.89 , pp. 1121-1131
    • Solh, M.1    Yohe, S.2    Weisdorf, D.3
  • 19
    • 77956398973 scopus 로고    scopus 로고
    • High Expression of the very late antigen-4 integrin independently predicts reduced risk of relapse and improved outcome in pediatric acute myeloid leukemia: A report from the Children's Oncology Group
    • Walter RB, Alonzo TA, Gerbing RB, et al. High Expression of the very late antigen-4 integrin independently predicts reduced risk of relapse and improved outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group. J Clin Oncol 2010; 28:2831-2838.
    • (2010) J Clin Oncol , vol.28 , pp. 2831-2838
    • Walter, R.B.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 20
    • 0035339877 scopus 로고    scopus 로고
    • Comparison of cytogenetic and molecular genetic detection of t(8;21) and inv(16) in a prospective series of adults with de novo acute myeloid leukemia: A Cancer and Leukemia Group B Study
    • Mrózek K, Prior TW, Edwards C, et al. Comparison of cytogenetic and molecular genetic detection of t(8;21) and inv(16) in a prospective series of adults with de novo acute myeloid leukemia: a Cancer and Leukemia Group B Study. J Clin Oncol 2001; 19:2482-2492.
    • (2001) J Clin Oncol , vol.19 , pp. 2482-2492
    • Mrózek, K.1    Prior, T.W.2    Edwards, C.3
  • 21
    • 84863418375 scopus 로고    scopus 로고
    • KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice
    • Zhao L, Melenhorst JJ, Alemu L, et al. KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice. Blood 2012; 119:1511-1521.
    • (2012) Blood , vol.119 , pp. 1511-1521
    • Zhao, L.1    Melenhorst, J.J.2    Alemu, L.3
  • 22
    • 33646432204 scopus 로고    scopus 로고
    • Prognostic impact of c-KIT mutations in core binding factor leukemias: An Italian retrospective study
    • Cairoli R, Beghini A, Grillo G, et al. Prognostic impact of c-KIT mutations in core binding factor leukemias: an Italian retrospective study. Blood 2006;107:3463-3468.
    • (2006) Blood , vol.107 , pp. 3463-3468
    • Cairoli, R.1    Beghini, A.2    Grillo, G.3
  • 23
    • 34548018092 scopus 로고    scopus 로고
    • Gene-expression profiling identifies distinct subclasses of core binding factor acute myeloid leukemia
    • Bullinger L, Rucker FG, Kurz S, et al. Gene-expression profiling identifies distinct subclasses of core binding factor acute myeloid leukemia. Blood 2007; 110:1291-1300.
    • (2007) Blood , vol.110 , pp. 1291-1300
    • Bullinger, L.1    Rucker, F.G.2    Kurz, S.3
  • 24
    • 33344465478 scopus 로고    scopus 로고
    • KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival
    • Schnittger S, Kohl TM, Haferlach T, et al. KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival. Blood 2006; 107:1791-1799.
    • (2006) Blood , vol.107 , pp. 1791-1799
    • Schnittger, S.1    Kohl, T.M.2    Haferlach, T.3
  • 25
    • 33748467435 scopus 로고    scopus 로고
    • Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): A Cancer and Leukemia Group B Study
    • Paschka P, Marcucci G, Ruppert AS, et al. Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a Cancer and Leukemia Group B Study. J Clin Oncol 2006; 24:3904-3911.
    • (2006) J Clin Oncol , vol.24 , pp. 3904-3911
    • Paschka, P.1    Marcucci, G.2    Ruppert, A.S.3
  • 26
    • 77950612017 scopus 로고    scopus 로고
    • Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML
    • Pollard JA, Alonzo TA, Gerbing RB, et al. Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML. Blood 2010;115:2372-2379.
    • (2010) Blood , vol.115 , pp. 2372-2379
    • Pollard, J.A.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 27
    • 84916201282 scopus 로고    scopus 로고
    • Prevalence and prognostic significance of c-KIT mutations in core binding factor acute myeloid leukemia: A comprehensive large-scale study from a single Chinese center
    • Qin YZ, Zhu HH, Jiang Q, et al. Prevalence and prognostic significance of c-KIT mutations in core binding factor acute myeloid leukemia: a comprehensive large-scale study from a single Chinese center. Leuk Res 2014; 38:1435-1440.
    • (2014) Leuk Res , vol.38 , pp. 1435-1440
    • Qin, Y.Z.1    Zhu, H.H.2    Jiang, Q.3
  • 28
    • 84872335622 scopus 로고    scopus 로고
    • inv(16)/t(16;16) acute myeloid leukemia with nontype A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations
    • Schwind S, Edwards CG, Nicolet D, et al. inv(16)/t(16;16) acute myeloid leukemia with nontype A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations. Blood 2013; 121:385-391.
    • (2013) Blood , vol.121 , pp. 385-391
    • Schwind, S.1    Edwards, C.G.2    Nicolet, D.3
  • 29
    • 84923252988 scopus 로고    scopus 로고
    • Acute leukemia of ambiguous lineage with trisomy 4 as the sole cytogenetic abnormality: A case report and literature review
    • Moraveji S, Torabi A, Nahleh Z, et al. Acute leukemia of ambiguous lineage with trisomy 4 as the sole cytogenetic abnormality: a case report and literature review. Leuk Res Rep 2014; 3:33-35.
    • (2014) Leuk Res Rep , vol.3 , pp. 33-35
    • Moraveji, S.1    Torabi, A.2    Nahleh, Z.3
  • 30
    • 84859261475 scopus 로고    scopus 로고
    • Molecular and clinicopathologic characterization of AML with isolated trisomy 4
    • Bains A, Lu G, Yao H, et al. Molecular and clinicopathologic characterization of AML with isolated trisomy 4. Am J Clin Pathol 2012; 137:387-394.
    • (2012) Am J Clin Pathol , vol.137 , pp. 387-394
    • Bains, A.1    Lu, G.2    Yao, H.3
  • 31
    • 84904040673 scopus 로고    scopus 로고
    • High number of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: Frequency and impact on clinical outcome
    • Krauth MT, Eder C, Alpermann T, et al. High number of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: frequency and impact on clinical outcome. Leukemia 2014; 28:1449-1458.
    • (2014) Leukemia , vol.28 , pp. 1449-1458
    • Krauth, M.T.1    Eder, C.2    Alpermann, T.3
  • 32
    • 34548029756 scopus 로고    scopus 로고
    • FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia
    • Mead AJ, Linch DC, Hills RK, et al. FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia. Blood 2007; 110:1262-1270.
    • (2007) Blood , vol.110 , pp. 1262-1270
    • Mead, A.J.1    Linch, D.C.2    Hills, R.K.3
  • 33
    • 33744487375 scopus 로고    scopus 로고
    • Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBF-AML)
    • Boissel N, Leroy H, Brethon B, et al. Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBF-AML). Leukemia 2006; 20:965-970.
    • (2006) Leukemia , vol.20 , pp. 965-970
    • Boissel, N.1    Leroy, H.2    Brethon, B.3
  • 34
    • 0036659931 scopus 로고    scopus 로고
    • Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: Correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease
    • Schnittger S, Schoch C, Dugas M, et al. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood 2002; 100:59-66.
    • (2002) Blood , vol.100 , pp. 59-66
    • Schnittger, S.1    Schoch, C.2    Dugas, M.3
  • 35
    • 84883742457 scopus 로고    scopus 로고
    • The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in corebinding factor acute myeloid leukemia
    • Allen C, Hills RK, Lamb K, et al. The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in corebinding factor acute myeloid leukemia. Leukemia 2013; 27:1891-1901.
    • (2013) Leukemia , vol.27 , pp. 1891-1901
    • Allen, C.1    Hills, R.K.2    Lamb, K.3
  • 36
    • 77952420655 scopus 로고    scopus 로고
    • AML with CBFB-MYH11 rearrangement demonstrate RAS pathway alterations in 92% of all cases including a high frequency of NF1 deletions
    • Haferlach C, Dicker F, Kohlmann A, et al. AML with CBFB-MYH11 rearrangement demonstrate RAS pathway alterations in 92% of all cases including a high frequency of NF1 deletions. Leukemia 2010; 24:1065-1069.
    • (2010) Leukemia , vol.24 , pp. 1065-1069
    • Haferlach, C.1    Dicker, F.2    Kohlmann, A.3
  • 37
    • 26944447953 scopus 로고    scopus 로고
    • Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia
    • Goemans BF, Zwaan CM, Miller M, et al. Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia. Leukemia 2005; 19:1536-1542.
    • (2005) Leukemia , vol.19 , pp. 1536-1542
    • Goemans, B.F.1    Zwaan, C.M.2    Miller, M.3
  • 38
    • 33646575624 scopus 로고    scopus 로고
    • Implications of NRAS mutations in AML: A study of 2502 patients
    • Bacher U, Haferlach T, Schoch C, et al. Implications of NRAS mutations in AML: a study of 2502 patients. Blood 2006; 107:3847-3853.
    • (2006) Blood , vol.107 , pp. 3847-3853
    • Bacher, U.1    Haferlach, T.2    Schoch, C.3
  • 39
    • 53749099948 scopus 로고    scopus 로고
    • Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: A Cancer and Leukemia Group B study
    • Neubauer A, Maharry K, Mrózek K, et al. Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study. J Clin Oncol 2008;26:4603-4609.
    • (2008) J Clin Oncol , vol.26 , pp. 4603-4609
    • Neubauer, A.1    Maharry, K.2    Mrózek, K.3
  • 40
    • 55749099505 scopus 로고    scopus 로고
    • Distinct microRNA expression profiles in acute myeloid leukemia with common translocations
    • Li Z, Lu J, Sun M, et al. Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proc Natl Acad Sci U S A 2008; 105:15535-15540.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 15535-15540
    • Li, Z.1    Lu, J.2    Sun, M.3
  • 41
    • 46749108531 scopus 로고    scopus 로고
    • MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia
    • Jongen-Lavrencic M, Sun SM, Dijkstra MK, et al. MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia. Blood 2008; 111:5078-5085.
    • (2008) Blood , vol.111 , pp. 5078-5085
    • Jongen-Lavrencic, M.1    Sun, S.M.2    Dijkstra, M.K.3
  • 42
    • 17544388046 scopus 로고    scopus 로고
    • Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype
    • Bloomfield CD, Lawrence D, Byrd JC, et al. Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype. Cancer Res 1998; 58:4173-4179.
    • (1998) Cancer Res , vol.58 , pp. 4173-4179
    • Bloomfield, C.D.1    Lawrence, D.2    Byrd, J.C.3
  • 43
    • 1842614240 scopus 로고    scopus 로고
    • Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): Results from CALGB 8461
    • Byrd JC, Ruppert AS, Mrozek K, et al. Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): results from CALGB 8461. J Clin Oncol 2004;22:1087-1094.
    • (2004) J Clin Oncol , vol.22 , pp. 1087-1094
    • Byrd, J.C.1    Ruppert, A.S.2    Mrozek, K.3
  • 44
    • 0032793987 scopus 로고    scopus 로고
    • Patients with t(8;21)(q22;q22) and acute myeloid leukemia have superior failure-free and overall survival when repetitive cycles of high-dose cytarabine are administered
    • 1
    • Byrd JC1, Dodge RK, Carroll A, et al. Patients with t(8;21)(q22;q22) and acute myeloid leukemia have superior failure-free and overall survival when repetitive cycles of high-dose cytarabine are administered. J Clin Oncol 1999;17:3767-3775.
    • (1999) J Clin Oncol , vol.17 , pp. 3767-3775
    • Byrd, J.C.1    Dodge, R.K.2    Carroll, A.3
  • 45
    • 84907549612 scopus 로고    scopus 로고
    • Anthracycline dose intensification improves molecular response and outcome of patients treated for core binding factor acute myeloid leukemia
    • Prebet T, Bertoli S, Delaunay J, et al. Anthracycline dose intensification improves molecular response and outcome of patients treated for core binding factor acute myeloid leukemia. Haematologica 2014; 99:e185-e187.
    • (2014) Haematologica , vol.99 , pp. e185-e187
    • Prebet, T.1    Bertoli, S.2    Delaunay, J.3
  • 46
    • 58149220896 scopus 로고    scopus 로고
    • Treatment of core-binding-factor in acute myelogenous leukemia with fludarabine, cytarabine, and granulocyte colony-stimulating factor results in improved event-free survival
    • Borthakur G, Kantarjian H, Wang X, et al. Treatment of core-binding-factor in acute myelogenous leukemia with fludarabine, cytarabine, and granulocyte colony-stimulating factor results in improved event-free survival. Cancer 2008; 113:3181-3185.
    • (2008) Cancer , vol.113 , pp. 3181-3185
    • Borthakur, G.1    Kantarjian, H.2    Wang, X.3
  • 47
    • 84869434807 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin: Time to resurrect?
    • Ravandi F, Estey EH, Appelbaum FR, et al. Gemtuzumab ozogamicin: time to resurrect? J Clin Oncol 2012; 30:3921-3923.
    • (2012) J Clin Oncol , vol.30 , pp. 3921-3923
    • Ravandi, F.1    Estey, E.H.2    Appelbaum, F.R.3
  • 48
    • 84905560676 scopus 로고    scopus 로고
    • Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: A meta-analysis of individual patient data from randomised controlled trials
    • Hills RK, Castaigne S, Appelbaum FR, et al. Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials. Lancet Oncol 2014; 15:986-996.
    • (2014) Lancet Oncol , vol.15 , pp. 986-996
    • Hills, R.K.1    Castaigne, S.2    Appelbaum, F.R.3
  • 49
    • 84908053861 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin with fludarabine, cytarabine, and granulocyte colony stimulating factor (FLAGGO) as front-line regimen in patients with core binding factor acute myelogenous leukemia
    • Borthakur G, Cortes JE, Estey EE, et al. Gemtuzumab ozogamicin with fludarabine, cytarabine, and granulocyte colony stimulating factor (FLAGGO) as front-line regimen in patients with core binding factor acute myelogenous leukemia. Am J Hematol 2014; 89:964-968.
    • (2014) Am J Hematol , vol.89 , pp. 964-968
    • Borthakur, G.1    Cortes, J.E.2    Estey, E.E.3
  • 50
    • 84902074946 scopus 로고    scopus 로고
    • Adding the KIT inhibitor dasatinib (DAS) to standard induction and consolidation therapy for newly diagnosed patients (pts) with core binding factor (CBF) acute myeloid leukemia (AML): Initial results of the CALGB 10801 (Alliance) Study
    • Marcucci G, Geyer S, Zhao J. Adding the KIT inhibitor dasatinib (DAS) to standard induction and consolidation therapy for newly diagnosed patients (pts) with core binding factor (CBF) acute myeloid leukemia (AML): initial results of the CALGB 10801 (Alliance) Study. Blood 2013; 122:357.
    • (2013) Blood , vol.122 , pp. 357
    • Marcucci, G.1    Geyer, S.2    Zhao, J.3
  • 51
    • 58149235277 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor romidepsin has differential activity in core binding factor acute myeloid leukemia
    • Odenike OM, Alkan S, Sher D, et al. Histone deacetylase inhibitor romidepsin has differential activity in core binding factor acute myeloid leukemia. Clin Cancer Res 2008; 14:7095-7101.
    • (2008) Clin Cancer Res , vol.14 , pp. 7095-7101
    • Odenike, O.M.1    Alkan, S.2    Sher, D.3
  • 52
    • 38349185874 scopus 로고    scopus 로고
    • HLA-identical sibling allogeneic transplants versus chemotherapy in acute myelogenous leukemia with t(8;21) in first complete remission: Collaborative study between the German AML Intergroup and CIBMTR
    • Schlenk RF, Pasquini MC, Perez WS, et al. HLA-identical sibling allogeneic transplants versus chemotherapy in acute myelogenous leukemia with t(8;21) in first complete remission: collaborative study between the German AML Intergroup and CIBMTR. Biol Blood Marrow Transplant 2008; 14:187-196.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 187-196
    • Schlenk, R.F.1    Pasquini, M.C.2    Perez, W.S.3
  • 53
    • 49249096735 scopus 로고    scopus 로고
    • Identical outcome after autologous or allogeneic genoidentical hematopoietic stem-cell transplantation in first remission of acute myelocytic leukemia carrying inversion 16 or t(8;21): A retrospective study from the European Cooperative Group for Blood and Marrow Transplantation
    • Gorin NC, Labopin M, Frassoni F, et al. Identical outcome after autologous or allogeneic genoidentical hematopoietic stem-cell transplantation in first remission of acute myelocytic leukemia carrying inversion 16 or t(8;21): a retrospective study from the European Cooperative Group for Blood and Marrow Transplantation. J Clin Oncol 2008; 26:3183-3188.
    • (2008) J Clin Oncol , vol.26 , pp. 3183-3188
    • Gorin, N.C.1    Labopin, M.2    Frassoni, F.3
  • 54
    • 34247325560 scopus 로고    scopus 로고
    • Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: Benefits for whom?
    • Cornelissen JJ, van Putten WL, Verdonck LF, et al. Results of a HOVON/ SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: benefits for whom? Blood 2007; 109:3658-3666.
    • (2007) Blood , vol.109 , pp. 3658-3666
    • Cornelissen, J.J.1    Van Putten, W.L.2    Verdonck, L.F.3
  • 55
    • 77953521033 scopus 로고    scopus 로고
    • Re-analysis of the outcomes of postremission therapy for acute myeloid leukemia with core binding factor according to years of patient enrollment
    • 1
    • Shin HJ1, Kim HJ, Sohn SK, et al. Re-analysis of the outcomes of postremission therapy for acute myeloid leukemia with core binding factor according to years of patient enrollment. Jpn J Clin Oncol 2010; 40:556-566.
    • (2010) Jpn J Clin Oncol , vol.40 , pp. 556-566
    • Shin, H.J.1    Kim, H.J.2    Sohn, S.K.3
  • 56
    • 61849159227 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for core binding factor acute myeloid leukemia: T(8;21) and inv(16) represent different clinical outcomes
    • Kuwatsuka Y, Miyamura K, Suzuki R, et al. Hematopoietic stem cell transplantation for core binding factor acute myeloid leukemia: t(8;21) and inv(16) represent different clinical outcomes. Blood 2009; 113:2096-2103.
    • (2009) Blood , vol.113 , pp. 2096-2103
    • Kuwatsuka, Y.1    Miyamura, K.2    Suzuki, R.3
  • 57
    • 53749095234 scopus 로고    scopus 로고
    • Autologous stem cell transplantation with PCR-negative graft would be associated with a favorable outcome in core-binding factor acute myeloid leukemia
    • Nakasone H, Izutsu K, Wakita S, et al. Autologous stem cell transplantation with PCR-negative graft would be associated with a favorable outcome in core-binding factor acute myeloid leukemia. Biol Blood Marrow Transplant 2008; 14:1262-1269.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 1262-1269
    • Nakasone, H.1    Izutsu, K.2    Wakita, S.3
  • 58
    • 84907326228 scopus 로고    scopus 로고
    • Core-binding factor acute myeloid leukemia in first relapse: A retrospective study from the French AML Intergroup
    • Hospital MA, Prebet T, Bertoli S, et al. Core-binding factor acute myeloid leukemia in first relapse: a retrospective study from the French AML Intergroup. Blood 2014; 124:1312-1319.
    • (2014) Blood , vol.124 , pp. 1312-1319
    • Hospital, M.A.1    Prebet, T.2    Bertoli, S.3
  • 59
    • 0035469883 scopus 로고    scopus 로고
    • The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): Analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial
    • Grimwade D, Walker H, Harrison G, et al. The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial. Blood 2001; 98:1312-1320.
    • (2001) Blood , vol.98 , pp. 1312-1320
    • Grimwade, D.1    Walker, H.2    Harrison, G.3
  • 60
    • 70350450588 scopus 로고    scopus 로고
    • Acute myeloid leukemia with translocation (8;21) or inversion (16) in elderly patients treated with conventional chemotherapy: A collaborative study of the French CBF-AML intergroup
    • Prebet T, Boissel N, Reutenauer S, et al. Acute myeloid leukemia with translocation (8;21) or inversion (16) in elderly patients treated with conventional chemotherapy: a collaborative study of the French CBF-AML intergroup. J Clin Oncol 2009; 27:4747-4753.
    • (2009) J Clin Oncol , vol.27 , pp. 4747-4753
    • Prebet, T.1    Boissel, N.2    Reutenauer, S.3
  • 61
    • 0036197485 scopus 로고    scopus 로고
    • Balanced chromosome abnormalities inv(16) and t(15;17) in therapy-related myelodysplastic syndromes and acute leukemia: Report from an international workshop
    • Andersen MK, Larson RA, Mauritzson N, et al. Balanced chromosome abnormalities inv(16) and t(15;17) in therapy-related myelodysplastic syndromes and acute leukemia: report from an international workshop. Genes Chromosomes Cancer 2002; 33:395-400.
    • (2002) Genes Chromosomes Cancer , vol.33 , pp. 395-400
    • Andersen, M.K.1    Larson, R.A.2    Mauritzson, N.3
  • 62
    • 68549123422 scopus 로고    scopus 로고
    • Survival is poorer in patients with secondary core-binding factor acute myelogenous leukemia compared with de novo core-binding factor leukemia
    • Borthakur G, Lin E, Jain N, et al. Survival is poorer in patients with secondary core-binding factor acute myelogenous leukemia compared with de novo core-binding factor leukemia. Cancer 2009; 115:3217-3221.
    • (2009) Cancer , vol.115 , pp. 3217-3221
    • Borthakur, G.1    Lin, E.2    Jain, N.3
  • 63
    • 65349103909 scopus 로고    scopus 로고
    • Therapy-related acute myeloid leukemia with t(8;21) (q22;q22) shares many features with de novo acute myeloid leukemia with t(8;21)(q22;q22) but does not have a favorable outcome
    • Gustafson SA, Lin P, Chen SS, et al. Therapy-related acute myeloid leukemia with t(8;21) (q22;q22) shares many features with de novo acute myeloid leukemia with t(8;21)(q22;q22) but does not have a favorable outcome. Am J Clin Pathol 2009; 131:647-655.
    • (2009) Am J Clin Pathol , vol.131 , pp. 647-655
    • Gustafson, S.A.1    Lin, P.2    Chen, S.S.3
  • 64
    • 77955275396 scopus 로고    scopus 로고
    • High frequency of concomitant mastocytosis in patients with acute myeloid leukemia exhibiting the transforming KIT mutation D816 V
    • Fritsche-Polanz R, Fritz M, Huber A, et al. High frequency of concomitant mastocytosis in patients with acute myeloid leukemia exhibiting the transforming KIT mutation D816 V. Mol Oncol 2010; 4:335-346.
    • (2010) Mol Oncol , vol.4 , pp. 335-346
    • Fritsche-Polanz, R.1    Fritz, M.2    Huber, A.3
  • 65
    • 84884948790 scopus 로고    scopus 로고
    • Hidden mastocytosis in acute myeloid leukemia with t(8;21)(q22;q22)
    • Johnson RC, Savage NM, Chiang T, et al. Hidden mastocytosis in acute myeloid leukemia with t(8;21)(q22;q22). Am J Clin Pathol 2013; 140:525-535.
    • (2013) Am J Clin Pathol , vol.140 , pp. 525-535
    • Johnson, R.C.1    Savage, N.M.2    Chiang, T.3
  • 66
    • 33845193026 scopus 로고    scopus 로고
    • Neoplastic mast cells in systemic mastocytosis associated with t(8;21) acute myeloid leukemia are derived from the leukemic clone
    • Pullarkat V, Bedell V, Kim Y, et al. Neoplastic mast cells in systemic mastocytosis associated with t(8;21) acute myeloid leukemia are derived from the leukemic clone. Leuk Res 2007; 31:261-265.
    • (2007) Leuk Res , vol.31 , pp. 261-265
    • Pullarkat, V.1    Bedell, V.2    Kim, Y.3
  • 67
    • 0037405219 scopus 로고    scopus 로고
    • Systemic mastocytosis with associated clonal hematological nonmast-cell lineage disease: Analysis of clinicopathologic features and activating c-kit mutations
    • Pullarkat VA, Bueso-Ramos C, Lai R, et al. Systemic mastocytosis with associated clonal hematological nonmast-cell lineage disease: analysis of clinicopathologic features and activating c-kit mutations. Am J Hematol 2003;73:12-17.
    • (2003) Am J Hematol , vol.73 , pp. 12-17
    • Pullarkat, V.A.1    Bueso-Ramos, C.2    Lai, R.3
  • 68
    • 84886780840 scopus 로고    scopus 로고
    • Characterization of bone marrow mast cells in acute myeloid leukemia with t(8;21) (q22;q22); RUNX1-RUNX1T1
    • Pullarkat ST, Pullarkat V, Lagoo A, et al. Characterization of bone marrow mast cells in acute myeloid leukemia with t(8;21) (q22;q22); RUNX1-RUNX1T1. Leuk Res 2013; 37:1572-1575.
    • (2013) Leuk Res , vol.37 , pp. 1572-1575
    • Pullarkat, S.T.1    Pullarkat, V.2    Lagoo, A.3
  • 69
    • 0033749308 scopus 로고    scopus 로고
    • Mast cell disease associated with acute myeloid leukemia: Detection of a new c-kit mutation Asp816His
    • Pullarkat VA, Pullarkat ST, Calverley DC, Brynes RK. Mast cell disease associated with acute myeloid leukemia: detection of a new c-kit mutation Asp816His. Am J Hematol 2000; 65:307-309.
    • (2000) Am J Hematol , vol.65 , pp. 307-309
    • Pullarkat, V.A.1    Pullarkat, S.T.2    Calverley, D.C.3    Brynes, R.K.4
  • 70
    • 85027957783 scopus 로고    scopus 로고
    • Systemic mastocytosis with associated clonal hematological nonmast cell lineage disease: Clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components
    • Wang SA, Hutchinson L, Tang G, et al. Systemic mastocytosis with associated clonal hematological nonmast cell lineage disease: clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components. Am J Hematol 2013; 88:219-224.
    • (2013) Am J Hematol , vol.88 , pp. 219-224
    • Wang, S.A.1    Hutchinson, L.2    Tang, G.3
  • 71
    • 84905257818 scopus 로고    scopus 로고
    • Hematopoietic stem-cell transplantation for advanced systemic mastocytosis
    • Ustun C, Reiter A, Scott BL, et al. Hematopoietic stem-cell transplantation for advanced systemic mastocytosis. J Clin Oncol 2014; 32:3264-3274.
    • (2014) J Clin Oncol , vol.32 , pp. 3264-3274
    • Ustun, C.1    Reiter, A.2    Scott, B.L.3
  • 72
    • 84920861200 scopus 로고    scopus 로고
    • Prognosis and monitoring of core-binding factor acute myeloid leukemia: Current and emerging factors
    • Duployez N, Willekens C, Marceau-Renaut A, et al. Prognosis and monitoring of core-binding factor acute myeloid leukemia: current and emerging factors. Expert Rev Hematol 2015; 8:43-56.
    • (2015) Expert Rev Hematol , vol.8 , pp. 43-56
    • Duployez, N.1    Willekens, C.2    Marceau-Renaut, A.3
  • 73
    • 84913553522 scopus 로고    scopus 로고
    • Defining minimal residual disease in acute myeloid leukemia: Which platforms are ready for 'prime time'?
    • Grimwade D, Freeman SD. Defining minimal residual disease in acute myeloid leukemia: which platforms are ready for 'prime time'? Blood 2014; 124:3345-3355.
    • (2014) Blood , vol.124 , pp. 3345-3355
    • Grimwade, D.1    Freeman, S.D.2
  • 74
    • 84877930402 scopus 로고    scopus 로고
    • Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia
    • Jourdan E, Boissel N, Chevret S, et al. Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia. Blood 2013; 121:2213-2223.
    • (2013) Blood , vol.121 , pp. 2213-2223
    • Jourdan, E.1    Boissel, N.2    Chevret, S.3
  • 75
    • 84867297401 scopus 로고    scopus 로고
    • Minimal residual disease monitoring by quantitative RT-PCR in core binding factor AML allows risk stratification and predicts relapse: Results of the United Kingdom MRC AML-15 trial
    • Liu Yin JA, O'Brien MA, Hills RK, et al. Minimal residual disease monitoring by quantitative RT-PCR in core binding factor AML allows risk stratification and predicts relapse: results of the United Kingdom MRC AML-15 trial. Blood 2012; 120:2826-2835.
    • (2012) Blood , vol.120 , pp. 2826-2835
    • Liu Yin, J.A.1    O'Brien, M.A.2    Hills, R.K.3
  • 76
    • 84880991962 scopus 로고    scopus 로고
    • MRD-directed risk stratification treatment may improve outcomes of t(8;21) AML in the first complete remission: Results from the AML05 multicenter trial
    • 1
    • Zhu HH1, Zhang XH, Qin YZ, et al. MRD-directed risk stratification treatment may improve outcomes of t(8;21) AML in the first complete remission: results from the AML05 multicenter trial. Blood 2013; 121:4056-4062.
    • (2013) Blood , vol.121 , pp. 4056-4062
    • Zhu, H.H.1    Zhang, X.H.2    Qin, Y.Z.3
  • 77
    • 84923264876 scopus 로고    scopus 로고
    • RUNX1/RUNX1T1-based MRD-monitoring early after allogeneic transplantation rather than c-KIT mutations in adult t(8;21) AML allows further risk stratification
    • Epub ahead of print
    • Wang Y, Wu DP, Liu QF, et al. RUNX1/RUNX1T1-based MRD-monitoring early after allogeneic transplantation rather than c-KIT mutations in adult t(8;21) AML allows further risk stratification. Blood 2014. [Epub ahead of print]
    • (2014) Blood
    • Wang, Y.1    Wu, D.P.2    Liu, Q.F.3
  • 78
    • 75649091203 scopus 로고    scopus 로고
    • Strikingly different molecular relapse kinetics in NPM1c, PML-RARA, RUNX1-RUNX1T1, and CBFBMYH11 acute myeloid leukemias
    • Ommen HB, Schnittger S, Jovanovic JV, et al. Strikingly different molecular relapse kinetics in NPM1c, PML-RARA, RUNX1-RUNX1T1, and CBFBMYH11 acute myeloid leukemias. Blood 2010; 115:198-205.
    • (2010) Blood , vol.115 , pp. 198-205
    • Ommen, H.B.1    Schnittger, S.2    Jovanovic, J.V.3
  • 79
    • 84867603927 scopus 로고    scopus 로고
    • Comparative analysis of different approaches to measure treatment response in acute myeloid leukemia
    • Inaba H, Coustan-Smith E, Cao X, et al. Comparative analysis of different approaches to measure treatment response in acute myeloid leukemia. J Clin Oncol 2012; 30:3625-3632.
    • (2012) J Clin Oncol , vol.30 , pp. 3625-3632
    • Inaba, H.1    Coustan-Smith, E.2    Cao, X.3


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