Expression of different bacterial cytotoxins is controlled by two global transcription factors, CRP and Fis, that co-operate in a shared-recruitment mechanism

Biochemical Journal

Volumn 466, Issue , 2015, Pages 323-335

  Rossiter, Amanda E ^a   Godfrey, Rita E ^a   Connolly, Jack A ^a   Busby, Stephen J W ^a   Henderson, Ian R ^a   Browning, Douglas F ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Bacterial multi subunit RNA polymerase; Bacterial promoters; Enteroaggregative E. coli (EAEC); Shigella sonnei; Transcription initiation; Uropathogenic E. coli (UPEC)

Indexed keywords

BACTERIAL TOXIN; CYCLIC AMP BINDING PROTEIN; CYTOTOXIN; RNA POLYMERASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FIS; UNCLASSIFIED DRUG; UPSTREAM STIMULATORY FACTOR; BACTERIAL PROTEIN; CRP PROTEIN, E COLI; DNA DIRECTED RNA POLYMERASE; ENTEROTOXIN; ESCHERICHIA COLI PROTEIN; FACTOR FOR INVERSION STIMULATION; FIS PROTEIN, E COLI; PET PROTEIN, E COLI; SECRETED AUTOTRANSPORTER TOXIN, E COLI; SERINE PROTEINASE; SIGMA FACTOR;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; BIOINFORMATICS; CARBOXY TERMINAL SEQUENCE; CONSENSUS SEQUENCE; CONTROLLED STUDY; DENATURING GRADIENT GEL ELECTROPHORESIS; DNA BINDING; DNA SEQUENCE; ENTEROAGGREGATIVE ESCHERICHIA COLI; EXPRESSION VECTOR; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; RECOMBINANT PLASMID; REGULATORY MECHANISM; SEQUENCE ALIGNMENT; SHIGELLA SONNEI; TRANSCRIPTION INITIATION; TRANSCRIPTION INITIATION SITE; CHEMICAL STRUCTURE; CHEMISTRY; DNA FLANKING REGION; DNA RESPONSIVE ELEMENT; ENZYMOLOGY; ESCHERICHIA COLI K 12; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MUTATION; PATHOGENICITY; PROTEIN DOMAIN; UROPATHOGENIC ESCHERICHIA COLI;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; SHIGELLA SONNEI;

5' FLANKING REGION; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BACTERIAL TOXINS; CYCLIC AMP RECEPTOR PROTEIN; DNA-DIRECTED RNA POLYMERASES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENTEROTOXINS; ESCHERICHIA COLI K12; ESCHERICHIA COLI PROTEINS; FACTOR FOR INVERSION STIMULATION PROTEIN; GENE EXPRESSION REGULATION, BACTERIAL; MODELS, MOLECULAR; MUTATION; PROMOTER REGIONS, GENETIC; PROTEIN INTERACTION DOMAINS AND MOTIFS; RESPONSE ELEMENTS; SERINE ENDOPEPTIDASES; SHIGELLA SONNEI; SIGMA FACTOR; TRANSCRIPTION, GENETIC; UROPATHOGENIC ESCHERICHIA COLI;

EID: 84923206661     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20141315     Document Type: Article

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