The pic protease of enteroaggregative Escherichia coli promotes intestinal colonization and growth in the presence of mucin

Infection and Immunity

Volumn 77, Issue 6, 2009, Pages 2465-2473

  Harrington, Susan M ^a   Sheikh, Jalaluddin ^a,b   Henderson, Ian R ^c   Ruiz Perez, Fernando ^b   Cohen, Paul S ^d   Nataro, James P ^a,b,e  

^a University of Maryland School of Medicine Center for Vaccine Development   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d UNIVERSITY OF RHODE ISLAND   (United States)

^e UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI PROTEIN; MEMBRANE PROTEIN; MUCIN; PIC PROTEASE; SERINE DERIVATIVE; STREPTOMYCIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VIRULENCE FACTOR; HYALURONATE LYASE; PIC PROTEIN, E COLI; POLYSACCHARIDE LYASE; SERINE PROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BACTERIUM CULTURE; BACTERIUM MUTANT; CECUM; CONTROLLED STUDY; ENTEROAGGREGATIVE ESCHERICHIA COLI; EX VIVO STUDY; FECES CULTURE; FEMALE; FIMBRIA; GROWTH REGULATION; HISTOPATHOLOGY; INOCULATION; INTESTINE INFECTION; INTESTINE MUCOSA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN FUNCTION; SHIGELLA FLEXNERI; SINGLE NUCLEOTIDE POLYMORPHISM; STRAIN DIFFERENCE; WILD TYPE; AMINO ACID SUBSTITUTION; ANIMAL; BAGG ALBINO MOUSE; CHILD; ENZYME ACTIVE SITE; ENZYMOLOGY; ESCHERICHIA COLI; FECES; GENE DELETION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; VIRULENCE;

AMINO ACID SUBSTITUTION; ANIMALS; CATALYTIC DOMAIN; CECUM; CHILD; COLONY COUNT, MICROBIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FECES; FEMALE; GENE DELETION; HUMANS; INTESTINAL MUCOSA; MICE; MICE, INBRED BALB C; MUCINS; MUTAGENESIS, SITE-DIRECTED; POLYSACCHARIDE-LYASES; SERINE ENDOPEPTIDASES; SHIGELLA FLEXNERI; VIRULENCE; VIRULENCE FACTORS;

EID: 66549128947     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01494-08     Document Type: Article

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