Genotypic and Phenotypic Characterisation of Enteroaggregative Escherichia coli from Children in Rio de Janeiro, Brazil

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  França, Fernanda L S ^a   Wells, Timothy J ^b   Browning, Douglas F ^b   Nogueira, Raquel Tayar ^a   Sarges, Felipe Silva ^a   Pereira, Ana Claudia ^a   Cunningham, Adam F ^b   Lucheze, Kely ^a   Rosa, Ana Claudia Paula ^a   Henderson, Ian R ^b   de Luna, Marias das Graças ^a  

^a UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ASYMPTOMATIC INFECTION; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BACTERIUM ISOLATE; BIOFILM; BRAZIL; CAENORHABDITIS ELEGANS; CELL ASSAY; CHILD; DIARRHEA; DISEASE ASSOCIATION; DISEASE MODEL; ENTEROAGGREGATIVE ESCHERICHIA COLI; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; NEMATODIASIS; NONHUMAN; PARASITE CLEARANCE; PHENOTYPE; PRESCHOOL CHILD; STRAIN DIFFERENCE;

ANIMALS; BACTERIAL ADHESION; BIOFILMS; BRAZIL; CAENORHABDITIS ELEGANS; CASE-CONTROL STUDIES; CELL LINE; CHILD, PRESCHOOL; DIARRHEA; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; GENE DELETION; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; PHENOTYPE; VIRULENCE; VIRULENCE FACTORS;

EID: 84880801176     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069971     Document Type: Article

References (45)

1. Nataro JP, Kaper JB, (1998) Diarrheagenic Escherichia coli. Clin Microbiol Rev 11: 142-201.
2. Huang DB, Mohanty A, DuPont HL, Okhuysen PC, Chiang T, (2006) A review of an emerging enteric pathogen: enteroaggregative Escherichia coli. J Med Microbiol 55: 1303-1311.
3. Nataro JP, (2005) Enteroaggregative Escherichia coli pathogenesis. Curr Opin Gastroenterol 21: 4-8.
4. Rasko DA, Webster DR, Sahl JW, Bashir A, Boisen N, et al. (2011) Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany. N Engl J Med 365: 709-717.
5. Chattaway MA, Dallman T, Okeke IN, Wain J, (2011) Enteroaggregative E. coli O104 from an outbreak of HUS in Germany 2011, could it happen again? J Infect Dev Ctries 5: 425-436.
6. Baudry B, Savarino SJ, Vial P, Kaper JB, Levine MM, (1990) A sensitive and specific DNA probe to identify enteroaggregative Escherichia coli, a recently discovered diarrheal pathogen. J Infect Dis 161: 1249-1251.
7. Johnson TJ, Nolan LK, (2009) Pathogenomics of the virulence plasmids of Escherichia coli. Microbiol Mol Biol Rev 73: 750-774.
8. Sheikh J, Czeczulin JR, Harrington S, Hicks S, Henderson IR, et al. (2002) A novel dispersin protein in enteroaggregative Escherichia coli. J Clin Invest 110: 1329-1337.
9. Henderson IR, Hicks S, Navarro-Garcia F, Elias WP, Philips AD, et al. (1999) Involvement of the enteroaggregative Escherichia coli plasmid-encoded toxin in causing human intestinal damage. Infect Immun 67: 5338-5344.
10. Dudley EG, Thomson NR, Parkhill J, Morin NP, Nataro JP, (2006) Proteomic and microarray characterization of the AggR regulon identifies a pheU pathogenicity island in enteroaggregative Escherichia coli. Mol Microbiol 61: 1267-1282.
11. Fasano A, Noriega FR, Maneval DR Jr, Chanasongcram S, Russell R, et al. (1995) Shigella enterotoxin 1: an enterotoxin of Shigella flexneri 2a active in rabbit small intestine in vivo and in vitro. J Clin Invest 95: 2853-2861.
12. Chaudhuri RR, Sebaihia M, Hobman JL, Webber MA, Leyton DL, et al. (2010) Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. PLoS One 5: e8801.
13. Henderson IR, Czeczulin J, Eslava C, Noriega F, Nataro JP, (1999) Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli. Infect Immun 67: 5587-5596.
14. Henderson IR, Meehan M, Owen P, (1997) Antigen 43, a phase-variable bipartite outer membrane protein, determines colony morphology and autoaggregation in Escherichia coli K-12. FEMS Microbiol Lett 149: 115-120.
15. Nataro JP, Deng Y, Cookson S, Cravioto A, Savarino SJ, et al. (1995) Heterogeneity of enteroaggregative Escherichia coli virulence demonstrated in volunteers. J Infect Dis 171: 465-468.
16. Crossman LC, Chaudhuri RR, Beatson SA, Wells TJ, Desvaux M, et al. (2010) A commensal gone bad: complete genome sequence of the prototypical enterotoxigenic Escherichia coli strain H10407. J Bacteriol 192: 5822-5831.
17. Turner SM, Chaudhuri RR, Jiang ZD, DuPont H, Gyles C, et al. (2006) Phylogenetic comparisons reveal multiple acquisitions of the toxin genes by enterotoxigenic Escherichia coli strains of different evolutionary lineages. J Clin Microbiol 44: 4528-4536.
18. Kahali S, Sarkar B, Rajendran K, Khanam J, Yamasaki S, et al. (2004) Virulence characteristics and molecular epidemiology of enteroaggregative Escherichia coli isolates from hospitalized diarrheal patients in Kolkata, India. J Clin Microbiol 42: 4111-4120.
19. Wallace-Gadsden F, Johnson JR, Wain J, Okeke IN, (2007) Enteroaggregative Escherichia coli related to uropathogenic clonal group A. Emerg Infect Dis. 13: 757-760.
20. Estrada-Garcia T, Navarro-Garcia F, (2012) Enteroaggregative Escherichia coli pathotype: a genetically heterogeneous emerging foodborne enteropathogen. FEMS Immunol Med Microbiol 66: 281-298.
21. Jiang ZD, Greenberg D, Nataro JP, Steffen R, DuPont HL, (2002) Rate of occurrence and pathogenic effect of enteroaggregative Escherichia coli virulence factors in international travelers. J Clin Microbiol 40: 4185-4190.
22. Okeke IN, Lamikanra A, Czeczulin J, Dubovsky F, Kaper JB, et al. (2000) Heterogeneous virulence of enteroaggregative Escherichia coli strains isolated from children in Southwest Nigeria. J Infect Dis 181: 252-260.
23. Regua-Mangia AH, Gomes TA, Vieira MA, Irino K, Teixeira LM, (2009) Molecular typing and virulence of enteroaggregative Escherichia coli strains isolated from children with and without diarrhoea in Rio de Janeiro city, Brazil. J Med Microbiol 58: 414-422.
24. Itoh Y, Nagano I, Kunishima M, Ezaki T, (1997) Laboratory investigation of enteroaggregative Escherichia coli O untypeable:H10 associated with a massive outbreak of gastrointestinal illness. J Clin Microbiol 35: 2546-2550.
25. Rosa AC, Mariano AT, Pereira AM, Tibana A, Gomes TA, et al. (1998) Enteropathogenicity markers in Escherichia coli isolated from infants with acute diarrhoea and healthy controls in Rio de Janeiro, Brazil. J Med Microbiol 47: 781-790.
26. Finlay BB, Falkow S, (1997) Common themes in microbial pathogenicity revisited. Microbiol Mol Biol Rev 61: 136-169.
27. Picard B, Garcia JS, Gouriou S, Duriez P, Brahimi N, et al. (1999) The link between phylogeny and virulence in Escherichia coli extraintestinal infection. Infect Immun 67: 546-553.
28. Clermont O, Bonacorsi S, Bingen E, (2000) Rapid and simple determination of the Escherichia coli phylogenetic group. Appl Environ Microbiol 66: 4555-4558.
29. Pereira AC, Britto-Filho JD, Jose de Carvalho J, de Luna M, Rosa AC, (2008) Enteroaggregative Escherichia coli (EAEC) strains enter and survive within cultured intestinal epithelial cells. Microb Pathog 45: 310-314.
30. Mohamed JA, Huang DB, Jiang ZD, DuPont HL, Nataro JP, et al. (2007) Association of putative enteroaggregative Escherichia coli virulence genes and biofilm production in isolates from travelers to developing countries. J Clin Microbiol 45: 121-126.
31. Bhargava S, Johnson BB, Hwang J, Harris TA, George AS, et al. (2009) Heat-resistant agglutinin 1 is an accessory enteroaggregative Escherichia coli colonization factor. J Bacteriol 191: 4934-4942.
32. Hwang J, Mattei LM, VanArendonk LG, Meneely PM, Okeke IN, (2010) A pathoadaptive deletion in an enteroaggregative Escherichia coli outbreak strain enhances virulence in a Caenorhabditis elegans model. Infect Immun 78: 4068-4076.
33. Browning DF, Wells TJ, Franca FL, Morris FC, Sevastsyanovich YR, et al. (2013) Laboratory adapted Escherichia coli K-12 becomes a pathogen of Caenorhabditis elegans upon restoration of O antigen biosynthesis. Mol Microbiol.
34. Czeczulin JR, Whittam TS, Henderson IR, Navarro-Garcia F, Nataro JP, (1999) Phylogenetic analysis of enteroaggregative and diffusely adherent Escherichia coli. Infect Immun 67: 2692-2699.
35. Okeke IN, Wallace-Gadsden F, Simons HR, Matthews N, Labar AS, et al. (2010) Multi-locus sequence typing of enteroaggregative Escherichia coli isolates from Nigerian children uncovers multiple lineages. PLoS One 5: e14093.
36. Elias WP Jr, Czeczulin JR, Henderson IR, Trabulsi LR, Nataro JP, (1999) Organization of biogenesis genes for aggregative adherence fimbria II defines a virulence gene cluster in enteroaggregative Escherichia coli. J Bacteriol 181: 1779-1785.
37. Harrington SM, Sheikh J, Henderson IR, Ruiz-Perez F, Cohen PS, et al. (2009) The Pic protease of enteroaggregative Escherichia coli promotes intestinal colonization and growth in the presence of mucin. Infect Immun 77: 2465-2473.
38. Aballay A, Yorgey P, Ausubel FM, (2000) Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans. Curr Biol 10: 1539-1542.
39. Mellies JL, Barron AM, Haack KR, Korson AS, Oldridge DA, (2006) The global regulator Ler is necessary for enteropathogenic Escherichia coli colonization of Caenorhabditis elegans. Infect Immun 74: 64-72.
40. Shivers RP, Youngman MJ, Kim DH, (2008) Transcriptional responses to pathogens in Caenorhabditis elegans. Curr Opin Microbiol 11: 251-256.
41. Tan MW, Mahajan-Miklos S, Ausubel FM, (1999) Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis. Proc Natl Acad Sci U S A 96: 715-720.
42. Velarde JJ, Varney KM, Inman KG, Farfan M, Dudley E, et al. (2007) Solution structure of the novel dispersin protein of enteroaggregative Escherichia coli. Mol Microbiol 66: 1123-1135.
43. Escobar-Paramo P, Clermont O, Blanc-Potard AB, Bui H, Le Bouguenec C, et al. (2004) A specific genetic background is required for acquisition and expression of virulence factors in Escherichia coli. Mol Biol Evol 21: 1085-1094.
44. Nataro JP, Mai V, Johnson J, Blackwelder WC, Heimer R, et al. (2006) Diarrheagenic Escherichia coli infection in Baltimore, Maryland, and New Haven, Connecticut. Clin Infect Dis 43: 402-407.
45. Wilson A, Evans J, Chart H, Cheasty T, Wheeler JG, et al. (2001) Characterisation of strains of enteroaggregative Escherichia coli isolated during the infectious intestinal disease study in England. Eur J Epidemiol 17: 1125-1130.