Amyloidogenic lysozymes accumulate in the endoplasmic reticulum accompanied by the augmentation of ER stress signals

Biochimica et Biophysica Acta - General Subjects

Volumn 1850, Issue 6, 2015, Pages 1107-1119

  Kamada, Yoshiki ^a   Kusakabe, Takahiro ^b   Sugimoto, Yasushi ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Amyloidosis; Endoplasmic reticulum; ER stress; Lysozyme; Mutants

Indexed keywords

ARGININE; ASPARTIC ACID; GLUCOSE REGULATED PROTEIN 78; HISTIDINE; ISOLEUCINE; LYSOZYME; PHENYLALANINE; THREONINE; TRYPTOPHAN; X BOX BINDING PROTEIN 1; DNA BINDING PROTEIN; ERN1 PROTEIN, HUMAN; HEAT SHOCK PROTEIN; MESSENGER RNA; MOLECULAR CHAPERONE GRP78; PROTEIN SERINE THREONINE KINASE; REGULATORY FACTOR X TRANSCRIPTION FACTORS; RIBONUCLEASE; TRANSCRIPTION FACTOR;

ARTICLE; BIOACCUMULATION; CELL CULTURE; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM STRESS; ENZYME RELEASE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MUTANT; POINT MUTATION; PRIORITY JOURNAL; RNA INTERFERENCE; UNFOLDED PROTEIN RESPONSE; WILD TYPE; CHEMICAL STRUCTURE; CHEMISTRY; ENDOPLASMIC RETICULUM; ENZYMOLOGY; FAMILIAL AMYLOIDOSIS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; GENOTYPE; HEK293 CELL LINE; METABOLISM; MUTATION; PHENOTYPE; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

AMYLOIDOSIS, FAMILIAL; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENOTYPE; HEAT-SHOCK PROTEINS; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; MURAMIDASE; MUTATION; PHENOTYPE; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; TRANSFECTION; UNFOLDED PROTEIN RESPONSE;

EID: 84923163529     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2015.01.018     Document Type: Article

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