SCOPUS 정보 검색 플랫폼

Volumn 23, Issue 5, 2015, Pages 1189-1206

Synthesis, structure activity relationship, radiolabeling and preclinical evaluation of high affinity ligands for the ion channel of the N-methyl-d-aspartate receptor as potential imaging probes for positron emission tomography

(7) Klein, Pieter J a Christiaans, Johannes A M a Metaxas, Athanasios a Schuit, Robert C a Lammertsma, Adriaan A a Van Berckel, Bart N M a Windhorst, Albert D a

a VU UNIVERSITY MEDICAL CENTER (Netherlands)

Author keywords

Guanidines; Ion channel; NMDA; PET; Radiolabeling; Uncompetitive antagonists

Indexed keywords

1 BENZYL 3 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 METHYLGUANIDINE; 1 BENZYL 3 [2 CHLORO 5 (METHYLTHIO)PHENYL]GUANIDINE; 1 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 METHYL 1 PHENYLGUANIDINE; 1 [2 CHLORO 5 (METHYLTHIO)PHENYL] 3 (3 METHOXYBENZYL)GUANIDINE; 1 [2 CHLORO 5 (METHYLTHIO)PHENYL] 3 (3 METHOXYPHENETHYL)GUANIDINE; 1 [2 CHLORO 5 (METHYLTHIO)PHENYL] 3 (3 METHOXYPHENYL)GUANIDINE; 1 [2 CHLORO 5 (METHYLTHIO)PHENYL] 3 PHENETHYLGUANIDINE; 1 [2 CHLORO 5 (METHYLTHIO)PHENYL] 3 [3 (DIFLUOROMETHOXY)PHENYL] 1 METHYLGUANIDINE; 1 [2 CHLORO 5 (METHYLTHIO)PHENYL] 3 [3 (DIFLUOROMETHOXY)PHENYL]GUANIDINE; 1 [2 CHLORO 5 (METHYLTHIO)PHENYL] 3 [3 (TRIFLUOROMETHOXY)PHENYL] 1 METHYLGUANIDINE; 1 [2 CHLORO 5 (METHYLTHIO)PHENYL] 3 [3 (TRIFLUOROMETHOXY)PHENYL]GUANIDINE; 3 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 (3 HYDROXYPHENYL) 1 METHYLGUANIDINE; 3 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 (3 METHOXYBENZYL) 1 METHYLGUANIDINE; 3 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 (3 METHOXYPHENETHYL) 1 METHYLGUANIDINE; 3 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 (3 METHOXYPHENYL) 1 METHYLGUANIDINE; 3 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 METHYL 1 PHENETHYLGUANIDINE; 3 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 METHYL 1 PHENYLGUANIDINE; 3 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 METHYL 1 [3 (1,1,2,2 TETRAFLUOROETHOXY)PHENYL]GUANIDINE; 3 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 METHYL 1 [3 (TRIFLUOROMETHOXY)PHENYL]GUANIDINE; 3 [2 CHLORO 5 (METHYLTHIO)PHENYL] 1 [3 (DIFLUOROMETHOXY)PHENYL] 1 METHYLGUANIDINE; CARBON 11; DIARYLGUANIDINE DERIVATIVE; FLUORINE 18; GUANIDINE DERIVATIVE; N (3 METHOXYPHENYL)CYANAMIDE; N BENZYLCYANAMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N PHENETHYLCYANAMIDE; N PHENYLCYANAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; AFFINITY LABELING; ION CHANNEL; LIGAND;

ALKYLATION; ANALYSIS OF VARIANCE; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING SITE; BRAIN CORTEX; CEREBELLUM; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CORPUS STRIATUM; DRUG DISTRIBUTION; DRUG PURIFICATION; DRUG SYNTHESIS; EX VIVO STUDY; FOREBRAIN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; ISOTOPE LABELING; LIPOPHILICITY; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; RADIOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION; AFFINITY LABELING; ANIMAL; DRUG EFFECTS; METABOLISM; RAT; WISTAR RAT;

MUS; RATTUS;

AFFINITY LABELS; ANIMALS; AUTORADIOGRAPHY; ION CHANNELS; LIGANDS; MICE; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

EID: 84923088280 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2014.12.029 Document Type: Article

Times cited : (18)

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