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Volumn 134, Issue 4, 2011, Pages 979-986

Glutamate NMDA receptor dysregulation in Parkinson's disease with dyskinesias

Author keywords

dyskinesias; glutamate; levodopa; Parkinson; PET

Indexed keywords

CABERGOLINE; ION CHANNEL; LEVODOPA; N METHYL 3(THYOMETHYLPHENYL)CYANAMIDE C 11; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PERGOLIDE; PRAMIPEXOLE; RADIOPHARMACEUTICAL AGENT; RASAGILINE; ROPINIROLE; ROTIGOTINE; UNCLASSIFIED DRUG;

EID: 79953647380     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awr028     Document Type: Article
Times cited : (176)

References (46)
  • 1
    • 0035353725 scopus 로고    scopus 로고
    • Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature
    • DOI 10.1002/mds.1090
    • Ahlskog JE, Muenter MD. Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature. Mov Disord 2001; 16: 448-58. (Pubitemid 36041148)
    • (2001) Movement Disorders , vol.16 , Issue.3 , pp. 448-458
    • Ahlskog, J.E.1    Muenter, M.D.2
  • 4
    • 27744571228 scopus 로고    scopus 로고
    • Combined blockade of AMPA and NMDA glutamate receptors reduces levodopa-induced motor complications in animal models of PD
    • DOI 10.1016/j.expneurol.2005.08.017, PII S0014488605003171
    • Bibbiani F, Oh JD, Kielaite A, Collins MA, Smith C, Chase TN. Combined blockade of AMPA and NMDA glutamate receptors reduces levodopa-induced motor complications in animal models of PD. Exp Neurol 2005; 196: 422-29. (Pubitemid 41607831)
    • (2005) Experimental Neurology , vol.196 , Issue.2 , pp. 422-429
    • Bibbiani, F.1    Oh, J.D.2    Kielaite, A.3    Collins, M.A.4    Smith, C.5    Chase, T.N.6
  • 5
    • 34250619579 scopus 로고    scopus 로고
    • 3H]CNS-5161 - A use-dependent ligand for the N-methyl-D-aspartate receptor in rat brain
    • DOI 10.1002/syn.20400
    • Biegon A, Gibbs A, Alvarado M, Ono M, Taylor S. In vitro and in vivo characterization of [3H]CNS-5161-a use-dependent ligand for the N-methyl-D-aspartate receptor in rat brain. Synapse 2007; 61: 577-86. (Pubitemid 46934004)
    • (2007) Synapse , vol.61 , Issue.8 , pp. 577-586
    • Biegon, A.1    Gibbs, A.2    Alvarado, M.3    Ono, M.4    Taylor, S.5
  • 6
    • 1442300051 scopus 로고    scopus 로고
    • Effect of Riluzole on Dyskinesia and Duration of the ON State in Parkinson Disease Patients: A Double-Blind, Placebo-Controlled Pilot Study
    • DOI 10.1097/00002826-200401000-00008
    • Braz CA, Borges V, Ferraz HB. Effect of riluzole on dyskinesia and duration of the on state in Parkinson disease patients: a doubleblind, placebo-controlled pilot study. Clin Neuropharmacol 2004; 27: 25-9. (Pubitemid 38280384)
    • (2004) Clinical Neuropharmacology , vol.27 , Issue.1 , pp. 25-29
    • Braz, C.A.1    Borges, V.2    Ferraz, H.B.3
  • 8
    • 0034110849 scopus 로고    scopus 로고
    • Levodopa induced dyskinesia: A pathological form of striatal synaptic plasticity?
    • Calabresi P, Giacomini P, Centonze D, Bernardi G. Levodopa induced dyskinesia: a pathological form of striatal synaptic plasticity? Ann Neurol 2000; 47: 60-8.
    • (2000) Ann Neurol , vol.47 , pp. 60-68
    • Calabresi, P.1    Giacomini, P.2    Centonze, D.3    Bernardi, G.4
  • 10
    • 0346218258 scopus 로고    scopus 로고
    • Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease
    • DOI 10.1016/j.nbd.2003.07.003
    • Calon F, Rajput AH, Hornykiewicz O, Bedard PJ, Di Paolo T. Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease. Neurobiol Dis 2003; 14: 404-16. (Pubitemid 37543519)
    • (2003) Neurobiology of Disease , vol.14 , Issue.3 , pp. 404-416
    • Calon, F.1    Rajput, A.H.2    Hornykiewicz, O.3    Bedard, P.J.4    Di Paolo, T.5
  • 11
    • 34547484764 scopus 로고    scopus 로고
    • Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease
    • DOI 10.1523/JNEUROSCI.2079-07.2007
    • Carlsson T, Carta M, Winkler C, Bjö rklund A, Kirik D. Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease. J Neurosci 2007; 27: 8011-22. (Pubitemid 47173327)
    • (2007) Journal of Neuroscience , vol.27 , Issue.30 , pp. 8011-8022
    • Carlsson, T.1    Carta, M.2    Winkler, C.3    Bjorklund, A.4    Kirik, D.5
  • 12
    • 77953394342 scopus 로고    scopus 로고
    • Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease
    • Carta M, Carlsson T, Muñoz A, Kirik D, Bjö rklund A. Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease. Mov Disord 2010; 25(Suppl. 1): S174-9.
    • (2010) Mov Disord , vol.25 , Issue.SUPPL. 1
    • Carta, M.1    Carlsson, T.2    Muñoz, A.3    Kirik, D.4    Bjö Rklund, A.5
  • 13
    • 0033677879 scopus 로고    scopus 로고
    • Striatal dopamine- and glutamate-mediated dysregulation in experimental parkinsonism
    • Chase TN, Oh JD. Striatal dopamine- and glutamate-mediated dysregulation in experimental parkinsonism. Trends Neurosci 2000; 23(Suppl. 10): S86-91.
    • (2000) Trends Neurosci , vol.23 , Issue.SUPPL. 10
    • Chase, T.N.1    Oh, J.D.2
  • 16
    • 10344236071 scopus 로고    scopus 로고
    • Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: Implications for dyskinesias
    • DOI 10.1093/brain/awh290
    • De la Fuente-Fernández R, Sossi V, Huang Z, Furtado S, Lu JQ, Calne DB, et al. Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias. Brain 2004; 127: 2747-54. (Pubitemid 39627382)
    • (2004) Brain , vol.127 , Issue.12 , pp. 2747-2754
    • De La Fuente-Fernandez, R.1    Sossi, V.2    Huang, Z.3    Furtado, S.4    Lu, J.-Q.5    Calne, D.B.6    Ruth, T.J.7    Stoessl, A.J.8
  • 17
    • 0035353741 scopus 로고    scopus 로고
    • Intravenous amantadine improves levadopa-induced dyskinesias: An acute double-blind placebo-controlled study
    • DOI 10.1002/mds.1112
    • Del Dotto P, Pavese N, Gambaccini G, Bernardini S, Metman LV, Chase TN, et al. Intravenous amantadine improves levadopa-induced dyskinesias: an acute double-blind placebo-controlled study. Mov Disord 2001; 16: 515-20. (Pubitemid 36041158)
    • (2001) Movement Disorders , vol.16 , Issue.3 , pp. 515-520
    • Del Dotto, P.1    Pavese, N.2    Gambaccini, G.3    Bernardini, S.4    Metman, L.V.5    Chase, T.N.6    Bonuccelli, U.7
  • 18
    • 0025765058 scopus 로고
    • Levodopa replacement therapy alters enzyme activities in striatum and neuropeptide content in striatal output regions of 6-hydroxydopamine lesioned rats
    • Engber TM, Susel Z, Kuo S, Gerfen CR, Chase TN. Levodopa replacement therapy alters enzyme activities in striatum and neuropeptide content in striatal output regions of 6-hydroxydopamine lesioned rats. Brain Res 1991; 552: 113-8.
    • (1991) Brain Res , vol.552 , pp. 113-118
    • Engber, T.M.1    Susel, Z.2    Kuo, S.3    Gerfen, C.R.4    Chase, T.N.5
  • 19
    • 0000224448 scopus 로고
    • Unified Parkinson's disease rating scale
    • Members of the UPDRS Development Committee Fahn S Marsden CD Calne DB Goldstein M editors Florham Park: MacMillan Headcare Information
    • Fahn S, Elton RL. Members of the UPDRS Development Committee. Unified Parkinson's disease rating scale. In: Fahn S, Marsden CD, Calne DB, Goldstein M, editors. Recent developments in Parkinson's disease, II. Florham Park: MacMillan Headcare Information; 1987. p. 153-64.
    • (1987) Recent Developments in Parkinson's Disease II , pp. 153-164
    • Fahn, S.1    Elton, R.L.2
  • 20
    • 0016823810 scopus 로고
    • Mini-mental state. A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-98.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 21
    • 0023273862 scopus 로고
    • The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain
    • Foster AC, Wong EH. The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain. Br J Pharmacol 1987; 91: 403-9. (Pubitemid 17083987)
    • (1987) British Journal of Pharmacology , vol.91 , Issue.2 , pp. 403-409
    • Foster, A.C.1    Wong, E.H.F.2
  • 22
    • 0032212206 scopus 로고    scopus 로고
    • Dopamine decreases the excitability of layer V pyramidal cells in the rat prefrontal cortex
    • Gulledge AT, Jaffe DB. Dopamine decreases the excitability of layer V pyramidal cells in the rat prefrontal cortex. J Neurosci 1998; 18: 9139-51. (Pubitemid 28491775)
    • (1998) Journal of Neuroscience , vol.18 , Issue.21 , pp. 9139-9151
    • Gulledge, A.T.1    Jaffe, D.B.2
  • 25
    • 33748784605 scopus 로고    scopus 로고
    • Automatic anatomical brain MRI segmentation combining label propagation and decision fusion
    • DOI 10.1016/j.neuroimage.2006.05.061, PII S1053811906006458
    • Heckemann RA, Hajnal JV, Aljabar P, Rueckert D, Hammers A. Automatic anatomical brain MRI segmentation combining label propagation and decision fusion. Neuroimage 2006; 33: 115-26. (Pubitemid 44404167)
    • (2006) NeuroImage , vol.33 , Issue.1 , pp. 115-126
    • Heckemann, R.A.1    Hajnal, J.V.2    Aljabar, P.3    Rueckert, D.4    Hammers, A.5
  • 26
    • 0141672033 scopus 로고    scopus 로고
    • Increased striatal pre-proenkephalin B expression is associated with dyskinesia in Parkinson's disease
    • DOI 10.1016/S0014-4886(03)00064-5
    • Henry B, Duty S, Fox SH, Crossman AR, Brotchie JM. Increased striatal pre-proenkephalin B expression is associated with dyskinesia in Parkinson's disease. Exp Neurol 2003; 183: 458-68. (Pubitemid 37205087)
    • (2003) Experimental Neurology , vol.183 , Issue.2 , pp. 458-468
    • Henry, B.1    Duty, S.2    Fox, S.H.3    Crossman, A.R.4    Brotchie, J.M.5
  • 27
    • 0037068833 scopus 로고    scopus 로고
    • A D2 class dopamine receptor transactivates a receptor tyrosine kinase to inhibit NMDA receptor transmission
    • DOI 10.1016/S0896-6273(02)00859-0
    • Kotecha SA, Oak JN, Jackson MF, Perez Y, Orser BA, Van Tol HH, et al. A D2 class dopamine receptor transactivates a receptor tyrosine kinase to inhibit NMDA receptor transmission. Neuron 2002; 35: 1111-22. (Pubitemid 35279538)
    • (2002) Neuron , vol.35 , Issue.6 , pp. 1111-1122
    • Kotecha, S.A.1    Oak, J.N.2    Jackson, M.F.3    Perez, Y.4    Orser, B.A.5    Van Tol, H.H.M.6    MacDonald, J.F.7
  • 28
    • 0032730121 scopus 로고    scopus 로고
    • Effect of memantine (NMDA antagonist) on Parkinson's disease: A double- blind crossover randomized study
    • Merello M, Nouzeilles MI, Cammarota A, Leiguarda R. Effect of mem-antine (NMDA antagonist) on Parkinson's disease: a doubleblind crossover randomized study. Clin Neuropharmacol 1999; 22: 273-6. (Pubitemid 29506396)
    • (1999) Clinical Neuropharmacology , vol.22 , Issue.5 , pp. 273-276
    • Merello, M.1    Nouzeilles, M.I.2    Cammarota, A.3    Leiguarda, R.4
  • 29
    • 0036589832 scopus 로고    scopus 로고
    • Characterisation of striatal NMDA receptors involved in the generation of Parkinsonian symptoms: Intrastriatal microinjection studies in the 6-OHDA-lesioned rat
    • DOI 10.1002/mds.10107
    • Nash JE, Brotchie JM. Characterisation of striatal NMDA receptors involved in the generation of parkinsonian symptoms: intrastriatal microinjection studies in the 6-OHDA-lesioned rat. Mov Disord 2002; 17: 455-66. (Pubitemid 36040956)
    • (2002) Movement Disorders , vol.17 , Issue.3 , pp. 455-466
    • Nash, J.E.1    Brotchie, J.M.2
  • 30
    • 0004521596 scopus 로고    scopus 로고
    • Enhanced tyrosine phosphorylation of striatal NMDA receptor subunits: Effect of dopaminergic denervation and L-DOPA administration
    • DOI 10.1016/S0006-8993(98)01049-X, PII S000689939801049X
    • Oh JD, Russell DS, Vaughan CL, Chase TN, Russell D. Enhanced tyrosine phosphorylation of striatal NMDA receptor subunits: effect of dopa-minergic denervation and L-DOPA administration. Brain Res 1998; 813: 150-9. (Pubitemid 29012528)
    • (1998) Brain Research , vol.813 , Issue.1 , pp. 150-159
    • Oh, J.D.1    Russell, D.2    Vaughan, C.L.3    Chase, T.N.4
  • 31
    • 0034793204 scopus 로고    scopus 로고
    • Evaluation of dyskinesias in a pilot, randomized, placebo-controlled trial of remacemide in advanced Parkinson disease
    • Parkinson Study Group
    • Parkinson Study Group. Evaluation of dyskinesias in a pilot, randomized, placebo-controlled trial of remacemide in advanced Parkinson disease. Arch Neurol 2001; 58: 1660-8.
    • (2001) Arch Neurol , vol.58 , pp. 1660-1668
  • 32
    • 33750975077 scopus 로고    scopus 로고
    • Clinical correlates of levodopa-induced dopamine release in Parkinson disease: A PET study
    • DOI 10.1212/01.wnl.0000242888.30755.5d, PII 0000611420061114000018
    • Pavese N, Evans AH, Tai YF, Hotton G, Brooks DJ, Lees AJ, et al. Clinical correlates of levodopa-induced dopamine release in Parkinson disease: a PET study. Neurology 2006; 67: 1612-7. (Pubitemid 44747932)
    • (2006) Neurology , vol.67 , Issue.9 , pp. 1612-1617
    • Pavese, N.1    Evans, A.H.2    Tai, Y.F.3    Hotton, G.4    Brooks, D.J.5    Lees, A.J.6    Piccini, P.7
  • 33
    • 4544347756 scopus 로고    scopus 로고
    • Chronic L-DOPA treatment increases extracellular glutamate levels and GLT1 expression in the basal ganglia in a rat model of Parkinson's disease
    • DOI 10.1111/j.1460-9568.2004.03591.x
    • Robelet S, Melon C, Guillet B, Salin P, Kerkerian-Le Goff L. Chronic L-DOPA treatment increases extracellular glutamate levels and GLT1 expression in the basal ganglia in a rat model of Parkinson's disease. Eur J Neurosci 2004; 20: 1255-66. (Pubitemid 39233578)
    • (2004) European Journal of Neuroscience , vol.20 , Issue.5 , pp. 1255-1266
    • Robelet, S.1    Melon, C.2    Guillet, B.3    Salin, P.4    Kerkerian-Le Goff, L.5
  • 34
    • 65349101603 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor II in the brains of Parkinsonian patients
    • Samadi P, Rajput A, Calon F, Gré goire L, Hornykiewicz O, Rajput AH, et al. Metabotropic glutamate receptor II in the brains of Parkinsonian patients. J Neuropathol Exp Neurol 2009; 68: 374-82.
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 374-382
    • Samadi P, R.1
  • 35
    • 0031028413 scopus 로고    scopus 로고
    • Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures
    • DOI 10.1118/1.598130
    • Studholme C, Hill DL, Hawkes DJ. Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures. Med Phys 1997; 24: 25-35. (Pubitemid 27051930)
    • (1997) Medical Physics , vol.24 , Issue.1 , pp. 25-35
    • Studholme, C.1    Hill, D.L.G.2    Hawkes, D.J.3
  • 36
    • 34247480145 scopus 로고    scopus 로고
    • D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons
    • DOI 10.1016/j.tins.2007.03.008, PII S0166223607000690, Fifty years of dopamine research
    • Surmeier DJ, Ding J, Day M, Wang Z, Shen W. D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons. Trends Neurosci 2007; 30: 228-35. (Pubitemid 46654239)
    • (2007) Trends in Neurosciences , vol.30 , Issue.5 , pp. 228-235
    • Surmeier, D.J.1    Ding, J.2    Day, M.3    Wang, Z.4    Shen, W.5
  • 37
    • 0037111484 scopus 로고    scopus 로고
    • Acute and repeated treatment with L-DOPA increase c-jun expression in the 6-hydroxydopamine-lesioned forebrain of rats and common marmosets
    • DOI 10.1016/S0006-8993(02)03289-4, PII S0006899302032894
    • Svenningsson P, Arts J, Gunne L, Andren PE. Acute and repeated treatment with L-DOPA increase c-jun expression in the 6-hydroxydopamine-lesioned forebrain of rats and common marmosets. Brain Res 2002; 955: 8-15. (Pubitemid 35284830)
    • (2002) Brain Research , vol.955 , Issue.1-2 , pp. 8-15
    • Svenningsson, P.1    Arts, J.2    Gunne, L.3    Andren, P.E.4
  • 38
    • 0029904201 scopus 로고    scopus 로고
    • Levodopa-induced changes in synaptic dopamine in patients with Parkinson's disease as measured by [11C]raclopride displacement and PET
    • Tedroff J, Pedersen M, Aquilonius SM, Hartvig P, Jacobsson G, Langstrom B. Levodopa-induced changes in synaptic dopamine in patients with Parkinson's disease as measured by [11C]raclopride displacement and PET. Neurology 1996; 46: 1430-6.
    • (1996) Neurology , vol.46 , pp. 1430-1436
    • Tedroff, J.1    Pedersen, M.2    Aquilonius, S.M.3    Hartvig, P.4    Jacobsson, G.5    Langstrom, B.6
  • 39
    • 2342581472 scopus 로고    scopus 로고
    • 2A Receptor mRNA in 6-Hydroxydopamine-Lesioned Rats Intermittently Treated with L-DOPA
    • DOI 10.1002/syn.20011
    • Tomiyama M, Kimura T, Maeda T, Tanaka H, Kannari K, Baba M. Upregulation of striatal adenosine A2A receptor mRNA in 6-hydroxydopamine-lesioned rats intermittently treated with L-DOPA. Synapse 2004; 52: 218-22. (Pubitemid 38581671)
    • (2004) Synapse , vol.52 , Issue.3 , pp. 218-222
    • Tomiyama, M.1    Kimura, T.2    Maeda, T.3    Tanaka, H.4    Kannari, K.5    Baba, M.A.6
  • 40
    • 0028179229 scopus 로고
    • The use of spectral analysis to determine regional cerebral glucose utilization with positron emission tomography and [18F]fluorodeoxyglucose: Theory, implementation, and optimization procedures
    • Turkheimer F, Moresco RM, Lucignani G, Sokoloff L, Fazio F, Schmidt K. The use of spectral analysis to determine regional cerebral glucose utilization with positron emission tomography and [18F]fluorodeoxyglucose: theory, implementation, and optimization procedures. J Cereb Blood Flow Metab 1994; 14: 406-22.
    • (1994) J Cereb Blood Flow Metab , vol.14 , pp. 406-422
    • Turkheimer, F.1    Moresco, R.M.2    Lucignani, G.3    Sokoloff, L.4    Fazio, F.5    Schmidt, K.6
  • 44
    • 0345084477 scopus 로고    scopus 로고
    • Dextromethorphan improves levodopa-induced dyskinesias in Parkinson's disease
    • Verhagen-Metman L, Del Dotto P, Natté R, van den Munckhof P, Chase TN. Dextromethorphan improves levodopa-induced dyskinesias in Parkinson's disease. Neurology 1998a; 51: 203-6. (Pubitemid 28345384)
    • (1998) Neurology , vol.51 , Issue.1 , pp. 203-206
    • Verhagen Metman, L.1    Del Dotto, P.2    Natte, R.3    Van Den Munckhof, P.4    Chase, T.N.5
  • 46
    • 0034103771 scopus 로고    scopus 로고
    • Alterations in preproenkephalin and adenosine-2a receptor mRNA, but not preprotachykinin mRNA correlate with occurrence of dyskinesia in normal monkeys chronically treated with L-DOPA
    • DOI 10.1046/j.1460-9568.2000.00988.x
    • Zeng BY, Pearce RK, MacKenzie GM, Jenner P. Alterations in preproen-kephalin and adenosine-2a receptor mRNA, but not preprotachykinin mRNA correlate with occurrence of dyskinesia in normal monkeys chronically treated with L-DOPA. Eur J Neur 2000; 12: 1096-104. (Pubitemid 30168788)
    • (2000) European Journal of Neuroscience , vol.12 , Issue.3 , pp. 1096-1104
    • Zeng, B.-Y.1    Pearce, R.K.B.2    MacKenzie, G.M.3    Jenner, P.4


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