Evaluation of [18F]VUF 5000 as a potential PET ligand for brain imaging of the histamine H3 receptor

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 9, 1999, Pages 1761-1767

  Windhorst, Albert D ^a   Timmerman, Henk ^a   Klok, Rob P ^a   Menge, Wiro M P B ^a   Leurs, Rob ^a   Herscheid, Jacobus D M ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

18F; Biodistribution; Histamine H3 receptor; Positron emission tomography; Thioperamide; VUF 5000

Indexed keywords

FLUORINE 18; HISTAMINE H3 RECEPTOR; LIGAND; RADIOLIGAND; RADIOPHARMACEUTICAL AGENT; THIOPERAMIDE; DRUG DERIVATIVE; FLUORINE; PIPERIDINE DERIVATIVE; SERUM ALBUMIN; THIOUREA; VUF 5182;

ANIMAL EXPERIMENT; ARTICLE; BRAIN SCINTISCANNING; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG BINDING; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG UPTAKE; HUMAN; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT; REACTION ANALYSIS; ANIMAL; BRAIN; COMPUTER ASSISTED EMISSION TOMOGRAPHY; EVALUATION; MALE; METABOLISM; RADIOASSAY; SCINTISCANNING; TISSUE DISTRIBUTION; WISTAR RAT;

ANIMALS; BRAIN; EVALUATION STUDIES; FLUORINE RADIOISOTOPES; HUMANS; MALE; PIPERIDINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, HISTAMINE H3; SERUM ALBUMIN; THIOUREA; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0032589505     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00108-X     Document Type: Article

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