Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel, high-sensitivity multiplexed mutation detection platform

Oncotarget

Volumn 6, Issue 4, 2015, Pages 2549-2561

  Kidess, Evelyn ^a   Heirich, Kyra ^a   Wiggin, Matthew ^b,c   Vysotskaia, Valentina ^b,c   Visser, Brendan C ^a   Marziali, Andre ^b,c   Wiedenmann, Bertram ^d   Norton, Jeffrey A ^a   Lee, Mark ^b,c   Jeffrey, Stefanie S ^a   Poultsides, George A ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Boreal Genomics   (United States)

^c Charité University Hospital ^*  (Canada)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Biomarker; Circulating tumor DNA; Colon cancer; CtDNA; Hepatic metastasis

Indexed keywords

B RAF KINASE; CARCINOEMBRYONIC ANTIGEN; CIRCULATING TUMOR DNA; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG; BRAF PROTEIN, HUMAN; EGFR PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; ONCOPROTEIN; PIK3CA PROTEIN, HUMAN; PROTEIN P21; RAS PROTEIN;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; CANCER RECURRENCE; CANCER TISSUE; CLINICAL ARTICLE; COLORECTAL CANCER; COLORECTAL LIVER METASTASIS; COLORECTAL SURGERY; DNA DETERMINATION; FEMALE; GENE MUTATION; HUMAN; HUMAN TISSUE; LIMIT OF DETECTION; LIVER RESECTION; MALE; METASTASIS RESECTION; MUTATIONAL ANALYSIS; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; SEQUENCE SPECIFIC SYNCHRONOUS COEFFICIENT OF DRAG ALTERATION; VERY ELDERLY; BLOOD; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; GENETICS; METASTASIS; MIDDLE AGED; MUTATION; PROCEDURES; REPRODUCIBILITY;

ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; HUMANS; MALE; MIDDLE AGED; MUTATION; NEOPLASM METASTASIS; PHOSPHATIDYLINOSITOL 3-KINASES; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS P21(RAS); RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPRODUCIBILITY OF RESULTS;

EID: 84923066128     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3041     Document Type: Article

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