Oxidative stress, mitochondrial dysfunction and, inflammation common events in skin of patients with Fibromyalgia

Mitochondrion

Volumn 21, Issue , 2015, Pages 69-75

  Sánchez Domínguez, Benito ^a   Bullón, Pedro ^a   Román Malo, Lourdes ^a   Marín Aguilar, Fabiola ^a   Alcocer Gómez, Elísabet ^b   Carrión, Angel M ^c   Sánchez Alcazar, José Antonio ^b,d   Cordero, Mario D ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSIDAD PABLO DE OLAVIDE   (Spain)

^d UNIVERSIDAD AUTÓNOMA DE CHILE   (Chile)

Author keywords

Fibromyalgia; Inflammation; Mitochondrial dysfunction; Oxidative stress

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); TUMOR NECROSIS FACTOR ALPHA; UBIDECARENONE; UBIQUINOL CYTOCHROME C REDUCTASE;

ADULT; ARTICLE; BIOENERGY; CLINICAL ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; FEMALE; FIBROMYALGIA; HUMAN; HUMAN TISSUE; INFLAMMATION; MIDDLE AGED; OXIDATIVE STRESS; PATHOGENESIS; PERIPHERAL NERVE INJURY; PROTEIN EXPRESSION; SKIN BIOPSY; BIOPSY; ENERGY METABOLISM; MITOCHONDRION; PAIN; PATHOLOGY; PATHOPHYSIOLOGY; PERIPHERAL NERVE; PHYSIOLOGY; SKIN;

ADULT; BIOPSY; ENERGY METABOLISM; FEMALE; FIBROMYALGIA; HUMANS; INFLAMMATION; MIDDLE AGED; MITOCHONDRIA; OXIDATIVE STRESS; PAIN; PERIPHERAL NERVES; SKIN;

EID: 84923038980     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2015.01.010     Document Type: Article

References (30)

1. Bozkurt M., Oktayoglu P., Em S., et al. Serum coenzyme Q10 levels and oxidative status in patients with fibromyalgia syndrome. J. Musculoskelet. Pain 2014, 22:27-32.
2. Casanova-Molla J., Morales M., Garrabou G., et al. Mitochondrial loss indicates early axonal damage in small fiber neuropathies. J. Peripher. Nerv. Syst. 2012, 17:147-157.
3. Collins L.V1., Hajizadeh S., Holme E., et al. Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses. J. Leukoc. Biol. 2004, 75:995-1000.
4. Cordero M.D., Moreno-Fernández A.M., deMiguel M., et al. Coenzyme Q10 distribution in blood is altered in patients with fibromyalgia. Clin. Biochem. 2009, 42:732-735.
5. Cordero M.D., De Miguel M., Moreno-Fernández A.M., et al. Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implication in the pathogenesis of the disease. Arthritis Res. Ther. 2010, 12:R17.
6. Cordero M.D., Díaz-Parrado E., Carrión A.M., et al. Is inflammation a mitochondrial dysfunction-dependent event in fibromyalgia?. Antioxid. Redox Signal. 2013, 18:800-807.
7. Cordero M.D., Alcocer-Gómez E., de Miguel M., et al. Can coenzyme q10 improve clinical and molecular parameters in fibromyalgia?. Antioxid. Redox Signal. 2013, 19:1356-1361.
8. Haas R.H., Parikh S., Falk M.J., et al. The in-depth evaluation of suspected mitochondrial disease. Mol. Genet. Metab. 2008, 94:16-37.
9. Jaggi A.S., Singh N. Therapeutic targets for the management of peripheral nerve injury-induced neuropathic pain. CNS Neurol. Disord. Drug Targets 2011, 10:589-609.
10. Kalyan-Raman U.P., Kalyan-Raman K., Yunus M.B., et al. Muscle pathology in primary fibromyalgia syndrome: a light microscopic, histochemical and ultrastructural study. J. Rheumatol. 1984, 11:808-813.
11. Kim S.H., Kim D.H., Oh D.H., et al. Characteristic electron microscopic findings in the skin of patients with fibromyalgia-preliminary study. Clin. Rheumatol. 2008, 27:407-411.
12. Kim H.Y., Chung J.M., Chung K. Increased production of mitochondrial superoxide in the spinal cord induces pain behaviors in mice: the effect of mitochondrial electron transport complex inhibitors. Neurosci. Lett. 2008, 447:87-91.
13. Lawrence R.C., Felson D.T., Helmick C.G., et al. National Arthritis Data Workgroup: estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum. 2008, 58:26-35.
14. López-Armada M.J1., Riveiro-Naveira R.R., Vaamonde-García C., et al. Mitochondrial dysfunction and the inflammatory response. Mitochondrion 2013, 13:106-118.
15. Lucas H.J., Brauch C.M., Settas L., et al. Fibromyalgia-new concepts of pathogenesis and treatment. Int. J. Immunopathol. Pharmacol. 2006, 19:5-10.
16. Lupachyk S., Shevalye H., Maksimchyk Y., et al. PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function. Free Radic. Biol. Med. 2011, 50:1400-1409.
17. Malik A., Czajka A. Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?. Mitochondrion 2012, 13(5):481-492. (S1567-7249:00232-2).
18. Miyamae T., Seki M., Naga T., et al. Increased oxidative stress and coenzyme Q10 deficiency in juvenile fibromyalgia: amelioration of hypercholesterolemia and fatigue by ubiquinol-10 supplementation. Redox Rep. 2013, 18:12-19.
19. Naik E., Dixit V.M. Mitochondrial reactive oxygen species drive proinflammatory cytokine production. J. Exp. Med. 2011, 208:417-420.
20. Naziroğlu M., Akkuş S., Soyupek F., et al. Vitamins C and E treatment combined with exercise modulates oxidative stress markers in blood of patients with fibromyalgia: a controlled clinical pilot study. Stress 2010, 13:498-505.
21. Quinzii C., Naini A., Salviati L., et al. A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency. Am. J. Hum. Genet. 2006, 78:345-349.
22. Rustin P., Chretien D., Bourgeron T., et al. Biochemical and molecular investigations in respiratory chain deficiencies. Clin. Chim. Acta 1994, 228:35-51.
23. Salemi S., Rethage J., Wollina U., et al. Detection of interleukin 1beta (IL-1beta), IL-6, and tumor necrosis factor-alpha in skin of patients with fibromyalgia. J. Rheumatol. 2003, 30:146-150.
24. Salemi S., Rethage J., Wollina U., et al. Detection of interleukin 1beta (IL-1beta), IL-6, and tumor necrosis factor-alpha in skin of patients with fibromyalgia. J. Rheumatol. 2003, 30:146-150.
25. Sánchez-Barceló E.J., Mediavilla M.D., Tan D.X., et al. Clinical uses of melatonin: evaluation of human trials. Curr. Med. Chem. 2010, 17:2070-2095.
26. Staud R. Is it all central sensitization? Role of peripheral tissue nociception in chronic musculoskeletal pain. Curr. Rheumatol. Rep. 2010, 12:448-454.
27. Staud R. Is it all central sensitization? Role of peripheral tissue nociception in chronic musculoskeletal pain. Curr. Rheumatol. Rep. 2010, 12:448-454.
28. Üçeyler N., Zeller D., Kahn A.K., et al. Small fibre pathology in patients with fibromyalgia syndrome. Brain 2013, 136:1857-1867.
29. Wolfe F., Walitt B.T., Katz R.S., et al. Longitudinal patterns of analgesic and central acting drug use and associated effectiveness in fibromyalgia. Eur. J. Pain 2013, 17:581-586.
30. Yunus M.B., Kalyan-Raman U.P., Kalyan-Raman K., et al. Pathologic changes in muscle in primary fibromyalgia syndrome. Am. J. Med. 1986, 81:38-42.