Detection of interleukin 1β (IL-1β), IL-6, and tumor necrosis factor-α in skin of patients with fibromyalgia

Journal of Rheumatology

Volumn 30, Issue 1, 2003, Pages 146-150

  Salemi, Souzan ^a   Rethage, Janine ^a   Wollina, Uwe ^b   Michel, Beat A ^a   Gay, Renate E ^a   Gay, Steffen ^a   Sprott, Haiko ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Cytokines; Fibromyalgia; Interleukins; Skin; Tumor necrosis factor

Indexed keywords

AVIDIN; BIOTIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; NONSTEROID ANTIINFLAMMATORY AGENT; RNA; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; INTERLEUKIN 1; MESSENGER RNA;

ADULT; ARTICLE; COLLAGEN METABOLISM; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; FEMALE; FIBROBLAST; FIBROMYALGIA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; NEUROGENIC INFLAMMATION; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; RNA ISOLATION; SKIN BIOPSY; SYNOVIUM; TISSUE LEVEL; BIOPSY; CHEMISTRY; FUNCTIONS OF THE SKIN AND ITS APPENDAGES; GENE EXPRESSION; GENETICS; IMMUNOLOGY; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; SKIN;

ADULT; BIOPSY; CYTOKINES; FEMALE; FIBROMYALGIA; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; INTERLEUKIN-6; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN; SKIN PHYSIOLOGY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037225083     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Wolfe F. Fibromyalgia: the clinical syndrome. Rheum Dis Clin North Am 1989;15:1-18.
2. Yunus MB, Khan MA, Rawlings KK, Green JR, Olson JM, Shah S. Genetic linkage analysis of multicase families with fibromyalgia syndrome. J Rheumatol 1999;26:408-12.
3. Culclasure TF, Enzenauer RJ, West SG. Post-traumatic stress disorder presenting as fibromyalgia. Am J Med 1993:94:548-9.
4. Weinberger LM. Traumatic fibromyositis: a critical review of an enigmatic concept. West J Med 1977;127:99-103.
5. Hudson JI, Hudson MS, Pliner LF, Goldenberg DL, Pope HG Jr. Fibromyalgia and major affective disorder: a controlled phenomenology and family history study. Am J Psychiatry 1985;142:441-6.
6. Ahles TA, Khan SA, Yunus MB, Spiegel DA, Masi AT. Psychiatric status of patients with primary fibromyalgia, patients with rheumatoid arthritis, and subjects without pain: a blind comparison of DSM-III diagnoses. Am J Psychiatry 1991;148:1721-6.
7. Goldenberg DL. Fibromyalgia and its relation to chronic fatigue syndrome, viral illness and immune abnormalities. J Rheumatol Suppl 1989;19:91-3.
8. Caro XJ. Is there an immunologic component to the fibrositis syndrome? Rheum Dis Clin North Am 1989;15:169-86.
9. Siegmeth W. Panalgesia and the fibromyalgia concept. Wien Med Wochenschr 1999;149:558-60.
10. Okifuji A, Turk DC, Marcus DA. Comparison of generalized and localized hyperalgesia in patients with recurrent headache and fibromyalgia. Psychosom Med 1999;61:771-80.
11. Schwarz MJ, Spath M, Muller-Bardorff H, Pongratz DE, Bondy B, Ackenheil M. Relationship of substance P, 5-hydroxyindole acetic acid and tryptophan in serum of fibromyalgia patients. Neurosci Lett 1999;259:196-8.
12. Offenbaecher M, Bondy B, de-Jonge S, et al. Possible association of fibromyalgia with a polymorphism in the serotonin transporter gene regulatory region. Arthritis Rheum 1999;42:2482-8.
13. Sprott H, Bradley LA, Oh SJ, et al. Immunohistochemical and molecular studies of serotonin, substance P, galanin, pituitary adenylyl cyclase-activating polypeptide, and secretoneurin in fibromyalgic muscle tissue. Arthritis Rheum 1998;41:1689-94.
14. Wikner J, Hirsch U, Wetterberg L, Rojdmark S. Fibromyalgia: a syndrome associated with decreased nocturnal melatonin secretion. Clin Endocrinol Oxf 1998;49:179-83.
15. Press J, Phillip M, Neumann L, et al. Normal melatonin levels in patients with fibromyalgia syndrome. J Rheumatol 1998;25:551-5.
16. Wallace DJ, Bowman R, Wormsley S, Peter J. Cytokines and immune regulation in the primary fibromyalgia (fibrositis) syndrome. Arthritis Rheum 1989;32:1334-5.
17. Hader N, Rimon D, Kinarty A, Lahat N. Altered interleukin-2 secretion in patients with fibromyalgia syndrome. Arthritis Rheum 1991;34:866-72.
18. Gur A, Karakoç M, Nas K, Cevik R, Denzli A, Saraq J. Cytokines and depression in cases with fibromyalgia. J Rheumatol 2002;29:358-61.
19. Sprott H, Muller A, Heine H. Collagen crosslinking in fibromyalgia. Arthritis Rheum 1997;40:1450-4.
20. Sporri B, Bickel M, Limat A, Waelti ER, Hunziker T, Wiesmann UN. Juxtacrine stimulation of cytokine production in cocultures of human dermal fibroblasts and T cells. Cytokine 1996;8:631-5.
21. Hu J, Cotgreave IA. Differential regulation of gap junctions by proinflammatory mediators in vitro. J Clin Invest 1997;99:2312-6.
22. Buchwald D, Wener MH, Pearlman T, Kith P. Markers of inflammation and immune activation in chronic fatigue and chronic fatigue syndrome. J Rheumatol 1997;24:372-6.
23. Wolfe F, Smythe HA, Yunus MB, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 1990;33:160-72.
24. Caro XJ, Wolfe F, Johnston WH. A controlled and blinded study of immunoreactant deposition at the dermal-epidermal junction of patients with primary fibrositis syndrome. J Rheumatol 1986;13:1086-92.
25. Caro XJ. Is there an immunologic component to the fibrositis syndrome? Rheum Dis Clin North Am 1989;15:169-86.
26. Salemi S, Rethage J, Kaeser L, et al. Detection of IL-I-beta, IL-6 and TNF-alpha in skin of fibromyalgia patients [abstract]. Arthritis Rheum 2001;44 Suppl:S69.
27. Wallace DJ, Linker-Israeli M, Hallegua D, Silverman S, Silver D, Weisman MH. Cytokines may play an aetiopathogenetic role in fibromyalgia: a hypothesis and pilot study. Rheumatology 2001;40:743-9.
28. Maes M, Libbrecht I, van Hunsel F, et al. The immuneinflammatory pathophysiology of fibromyalgia: increased serum soluble gp 130, the common signal transducer protein of various neurotrophic cytokines. Psychoneuroendocrinology 1999;24:371-83.
29. Meggs WJ. Neurogenic switching: a hypothesis for a mechanism for shifting the site of inflammation in allergy and chemical sensitivity. Environ Health Perspect 1995:103:54-6.
30. Enestrom S, Bengtsson A, Frodin T. Dermal IgG deposits and increase of mast cells in patients with fibromyalgia-relevant findings or epiphenomena? Scand J Rheumatol 1997;26:308-13.