Serum coenzyme Q10 levels and oxidative status in patients with fibromyalgia syndrome

Journal of Musculoskeletal Pain

Volumn 22, Issue 1, 2014, Pages 27-32

  Bozkurt, Mehtap ^a   Oktayoglu, Pelin ^a   Em, Serda ^a   Çaglayan, Mehmet ^a   Yuksel, Hatice ^a   Uçar, Demet ^a   Batmaz, Ibrahim ^a   Sariyildiz, Mustafa Akif ^a   Karatoprak, Seval ^a   Nas, Kemal ^a  

^a DICLE UNIVERSITY   (Turkey)

Author keywords

Coenzyme Q 10; Fatigue; Fibromyalgia syndrome

Indexed keywords

C REACTIVE PROTEIN; UBIDECARENONE;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME BLOOD LEVEL; ERYTHROCYTE SEDIMENTATION RATE; FATIGUE; FATIGUE IMPACT SCALE; FEMALE; FIBROMYALGIA; FIBROMYALGIA IMPACT QUESTIONNAIRE; HUMAN; LEUKOCYTE COUNT; MODIFIED FATIGUE IMPACT SCALE; OXIDATIVE STRESS; VISUAL ANALOG SCALE;

EID: 84896728992     PISSN: 10582452     EISSN: 15407012     Source Type: Journal    
DOI: 10.3109/10582452.2014.883040     Document Type: Article

References (33)

1. Neeck G: Pathogenic mechanisms of fibromyalgia. Ageing Res Rev 1: 243-255, 2002.
2. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, Tugwell P, et al: The American college of rheumatology 1990 criteria for the classification of fibromyalgia. Arthritis Rheum 33: 160-172, 1990.
3. Cordero MD: [Oxidative stress in fibromyalgia: Pathophysiology and clinical implications]. Reumatol Clin 7: 281-283, 2011.
4. Wang ZQ, Porreca F, Cuzzocrea S, Galen K, Lightfoot R, Masini E, Muscoli C, et al: A newly identified role for superoxide in inflammatory pain. J Pharmacol Exp Ther 309: 869-878, 2004.
5. Thomas SR, Neuzil J, Stocker R: Inhibition of LDL oxidation by ubiquinol-10. A protective mechanism for coenzyme Q in atherogenesis? Mol Aspects Med 18: S85-S103, 1997.
6. Quinzii CM, Lopez LC, Naini A, DiMauro S, Hirano M: Human CoQ10 deficiencies. Biofactors 32: 113-118, 2008.
7. Rauchova H, Battino M, Fato R, Lenaz G, Drahota Z: Coenzyme Q-pool function in glycerol-3-phosphate oxidation in hamster brown adipose tissue mitochondria. J Bioenerg Biomembr 24: 235-241, 1992.
8. Quinzii CM, Lopez LC, Von-Moltke J, Naini A, Krishna S, Schuelke M, Salviati L, et al: Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency. FASEB J: Official Publication of the Federation of American Societies for Experimental Biology 22: 1874-1885, 2008.
9. Cordero MD, De Miguel M, Moreno Fernandez AM, Carmona Lopez IM, Garrido Maraver J, Cotan D, Gomez Izquierdo L, et al: Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: Implications in the pathogenesis of the disease. Arthritis Res Ther 12: 1-11, 2010.
10. Cordero MD, Cotan D, del-Pozo-Martin Y, Carrion AM, de Miguel M, Bullon P, Sanchez-Alcazar JA: Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient. Nutrition 28: 1200-1203, 2012.
11. Burckhardt CS, Clark SR, Bennett RM: The fibromyalgia impact questionnaire: Development and validation. J Rheumatol 18: 728-733, 1991.
12. Armutlu K, Keser I, Korkmaz N, Akbiyik DI, Sümbülogilu V, Güney Z, Karabudak R: Psychometric study of Turkish version of Fatigue Impact Scale in multiple sclerosis patients. J Neurol Sci 255: 64-68, 2007.
13. Etemadifar M, Sayahi F, Abtahi S, Shemshaki H, Dorooshi G, Goodarzi M, Akbari M, Fereidan-Esfahani M: Ginseng in the treatment of fatigue in multiple sclerosis: A Randomized placebo-controlled double-blind pilot study. Int J Neurosci 123: 480-486, 2013.
14. Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD: The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol 46: 1121-1123, 1989.
15. Erel O: A novel automated method to measure total antioxidant response against potent free radical reactions. Clin Biochem 37: 112-119, 2004.
16. Erel O: A new automated colorimetric method for measuring total oxidant status. Clin Biochem 38: 1103-1111, 2005.
17. Bolukbas C, Bolukbas FF, Horoz M, Aslan M, Celik H, Erel O: Increased oxidative stress associated with the severity of the liver disease in various forms of hepatitis B virus infection. BMC Infect Dis 5: 95, 2005.
18. Kaplan P, Sebestianova N, Turiakova J, Kucera I: Determination of coenzyme Q in human plasma. Physiol Res/Acad Sci Bohemoslovaca 45: 39-45, 1996.
19. Cordero MD, Moreno-Fernandez AM, deMiguel M, Bonal P, Campa F, Jimenez-Jimenez LM, Ruiz-Losada A, et al: Coenzyme Q10 distribution in blood is altered in patients with fibromyalgia. Clin Biochem 42: 732-735, 2009.
20. Ozgocmen S, Ozyurt H, Sogut S, Akyol O: Current concepts in the pathophysiology of fibromyalgia: The potential role of oxidative stress and nitric oxide. Rheumatol Int 26: 585-597, 2006.
21. Littarru GP, Tiano L: Clinical aspects of coenzyme Q10: An update. Nutrition 26: 250-254, 2010.
22. Lenaz G, Fato R, Formiggini G, Genova ML: The role of coenzyme Q in mitochondrial electron transport. Mitochondrion 7: S8-S33, 2007.
23. Cordero MD, Diaz-Parrado E, Carrion AM, Alfonsi S, Sanchez-Alcazar JA, Bullon P, Battino M, de Miguel M: Is inflammation a mitochondrial dysfunction-dependent event in fibromyalgia? Antioxid Redox Signal 18: 800-807, 2013.
24. Cordero MD, Cano-Garcia FJ, Alcocer-Gomez E, De Miguel M, Sanchez-Alcazar JA: Oxidative stress correlates with headache symptoms in fibromyalgia: Coenzyme Q(1)(0) effect on clinical improvement. PloS One 7: e35677, 2012.
25. Cordero MD, Alcocer-Gomez E, de Miguel M, Cano-Garcia FJ, Luque CM, Fernandez-Riejo P, Fernandez AM, Sanchez-Alcazar JA: Coenzyme Q(10): A novel therapeutic approach for Fibromyalgia? Case series with 5 patients. Mitochondrion 11: 623-625, 2011.
26. Maes M, Mihaylova I, Kubera M, Uytterhoeven M, Vrydags N, Bosmans E: Lower plasma coenzyme Q10 in depression: A marker for treatment resistance and chronic fatigue in depression and a risk factor to cardiovascular disorder in that illness. Neuro Endocrinol Lett 30: 462-469, 2009.
27. Mannerkorpi K, Iversen MD: Physical exercise in fibromyalgia and related syndromes. Best Pract Res Clin Rheumatol 17: 629-647, 2003.
28. Alok R, Das SK, Agarwal GG, Salwahan L, Srivastava R: Relationship of severity of depression, anxiety and stress with severity of fibromyalgia. Clin Exp Rheumatol 29: S70-S72, 2011.
29. Maes M, Mihaylova I, Kubera M, Uytterhoeven M, Vrydags N, Bosmans E: Coenzyme Q10 deficiency in myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder. Neuro Endocrinol Lett 30: 470-476, 2009.
30. Altindag O, Celik H: Total antioxidant capacity and the severity of the pain in patients with fibromyalgia. Redox report: Commun Free Radical Res 11: 131-135, 2006.
31. Lund N, Bengtsson A, Thorborg P: Muscle tissue oxygen pressure in primary fibromyalgia. Scand J Rheumatol 15: 165-173, 1986.
32. Cakmak A, Soker M, Koc A, Erel O: Paraoxonase and arylesterase activity with oxidative status in children with thalassemia major. J Pediatr Hematol/Oncol 31: 583-587, 2009.
33. Neyal M, Yimenicioglu F, Aydeniz A, Taskin A, Saglam S, Cekmen M, Neyal A, et al: Plasma nitrite levels, total antioxidant status, total oxidant status, and oxidative stress index in patients with tension-type headache and fibromyalgia. Clin Neurol Neurosurg 115: 736-740, 2013.