메뉴 건너뛰기




Volumn 21, Issue 3, 2015, Pages 426-437

Evolutionary conservation of a molecular machinery for export and expression of mRNAs with retained introns

Author keywords

Conserved; CTE; Intron retention; Post transcriptional gene regulation; RNA element; RNA export

Indexed keywords

CIS ACTING ELEMENT; MESSENGER RNA; NUCLEOCYTOPLASMIC TRANSPORT PROTEIN; NXF1 PROTEIN, HUMAN; RNA BINDING PROTEIN;

EID: 84923017556     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.048520.114     Document Type: Article
Times cited : (14)

References (60)
  • 1
    • 0023932371 scopus 로고
    • Secreted placental alkaline phosphatase: A powerful new quantitative indicator of gene expression in eukaryotic cells
    • Berger J, Hauber J, Hauber R, Geiger R, Cullen BR. 1988. Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells. Gene 66: 1-10.
    • (1988) Gene , vol.66 , pp. 1-10
    • Berger, J.1    Hauber, J.2    Hauber, R.3    Geiger, R.4    Cullen, B.R.5
  • 2
    • 0035950262 scopus 로고    scopus 로고
    • Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin
    • Berke JD, Sgambato V, Zhu PP, Lavoie B, Vincent M, Krause M, Hyman SE. 2001. Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin. Neuron 32: 277-287.
    • (2001) Neuron , vol.32 , pp. 277-287
    • Berke, J.D.1    Sgambato, V.2    Zhu, P.P.3    Lavoie, B.4    Vincent, M.5    Krause, M.6    Hyman, S.E.7
  • 3
    • 0342505309 scopus 로고    scopus 로고
    • Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export
    • Black BE, Lévesque L, Holaska JM, Wood TC, Paschal BM. 1999. Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export. Mol Cell Biol 19: 8616-8624.
    • (1999) Mol Cell Biol , vol.19 , pp. 8616-8624
    • Black, B.E.1    Lévesque, L.2    Holaska, J.M.3    Wood, T.C.4    Paschal, B.M.5
  • 4
    • 33745145872 scopus 로고    scopus 로고
    • The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron
    • Bor YC, Swartz J, Morrison A, Rekosh D, Ladomery M, Hammarskjöld ML. 2006. The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron. Genes Dev 20: 1597-1608.
    • (2006) Genes Dev , vol.20 , pp. 1597-1608
    • Bor, Y.C.1    Swartz, J.2    Morrison, A.3    Rekosh, D.4    Ladomery, M.5    Hammarskjöld, M.L.6
  • 5
    • 0027955795 scopus 로고
    • A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent
    • Bray M, Prasad S, Dubay JW, Hunter E, Jeang KT, Rekosh D, Hammarskjöld ML. 1994. A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent. Proc Natl Acad Sci 91: 1256-1260.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 1256-1260
    • Bray, M.1    Prasad, S.2    Dubay, J.W.3    Hunter, E.4    Jeang, K.T.5    Rekosh, D.6    Hammarskjöld, M.L.7
  • 8
    • 79959291765 scopus 로고    scopus 로고
    • The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway
    • Coyle JH, Bor YC, Rekosh D, Hammarskjöld ML. 2011. The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway. RNA 17: 1344-1356.
    • (2011) RNA , vol.17 , pp. 1344-1356
    • Coyle, J.H.1    Bor, Y.C.2    Rekosh, D.3    Hammarskjöld, M.L.4
  • 9
  • 10
    • 0032489463 scopus 로고    scopus 로고
    • Two PDZ domain proteins encoded by the murine periaxin gene are the result of alternative intron retention and are differentially targeted in Schwann cells
    • Dytrych L, Sherman DL, Gillespie CS, Brophy PJ. 1998. Two PDZ domain proteins encoded by the murine periaxin gene are the result of alternative intron retention and are differentially targeted in Schwann cells. J Biol Chem 273: 5794-5800.
    • (1998) J Biol Chem , vol.273 , pp. 5794-5800
    • Dytrych, L.1    Sherman, D.L.2    Gillespie, C.S.3    Brophy, P.J.4
  • 11
    • 0031023533 scopus 로고    scopus 로고
    • A structured retroviral RNA element that mediates nucleocytoplasmic export of intron-containing RNA
    • Ernst RK, Bray M, Rekosh D, Hammarskjöld ML. 1997a. A structured retroviral RNA element that mediates nucleocytoplasmic export of intron-containing RNA. Mol Cell Biol 17: 135-144.
    • (1997) Mol Cell Biol , vol.17 , pp. 135-144
    • Ernst, R.K.1    Bray, M.2    Rekosh, D.3    Hammarskjöld, M.L.4
  • 12
    • 0031020033 scopus 로고    scopus 로고
    • Secondary structure and mutational analysis of the Mason-Pfizer monkey virus RNA constitutive transport element
    • Ernst RK, Bray M, Rekosh D, Hammarskjöld ML. 1997b. Secondary structure and mutational analysis of the Mason-Pfizer monkey virus RNA constitutive transport element. RNA 3: 210-222.
    • (1997) RNA , vol.3 , pp. 210-222
    • Ernst, R.K.1    Bray, M.2    Rekosh, D.3    Hammarskjöld, M.L.4
  • 13
    • 0000821902 scopus 로고
    • Rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA
    • Felber BK, Hadzopoulou-Cladaras M, Cladaras C, Copeland T, Pavlakis GN. 1989. rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA. Proc Natl Acad Sci 86: 1495-1499.
    • (1989) Proc Natl Acad Sci , vol.86 , pp. 1495-1499
    • Felber, B.K.1    Hadzopoulou-Cladaras, M.2    Cladaras, C.3    Copeland, T.4    Pavlakis, G.N.5
  • 15
    • 84893742732 scopus 로고    scopus 로고
    • The functional consequences of intron retention: Alternative splicing coupled to NMD as a regulator of gene expression
    • Ge Y, Porse BT. 2014. The functional consequences of intron retention: alternative splicing coupled to NMD as a regulator of gene expression. Bioessays 36: 236-243.
    • (2014) Bioessays , vol.36 , pp. 236-243
    • Ge, Y.1    Porse, B.T.2
  • 16
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham FL, van der Eb AJ. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52: 456-467.
    • (1973) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    Van Der Eb, A.J.2
  • 19
    • 0022533998 scopus 로고
    • High-level expression of the Epstein-Barr virus EBNA1 protein in CV1 cells and human lymphoid cells using a SV40 late replacement vector
    • Hammarskjöld ML, Wang SC, Klein G. 1986. High-level expression of the Epstein-Barr virus EBNA1 protein in CV1 cells and human lymphoid cells using a SV40 late replacement vector. Gene 43: 41-50.
    • (1986) Gene , vol.43 , pp. 41-50
    • Hammarskjöld, M.L.1    Wang, S.C.2    Klein, G.3
  • 21
    • 0028044759 scopus 로고
    • Human immunodeficiency virus env expression becomes Rev-independent if the env region is not defined as an intron
    • Hammarskjöld ML, Li H, Rekosh D, Prasad S. 1994. Human immunodeficiency virus env expression becomes Rev-independent if the env region is not defined as an intron. J Virol 68: 951-958.
    • (1994) J Virol , vol.68 , pp. 951-958
    • Hammarskjöld, M.L.1    Li, H.2    Rekosh, D.3    Prasad, S.4
  • 23
    • 3042836378 scopus 로고    scopus 로고
    • A molecular link between SR protein dephosphorylation and mRNA export
    • Huang Y, Yario TA, Steitz JA. 2004. A molecular link between SR protein dephosphorylation and mRNA export. Proc Natl Acad Sci 101: 9666-9670.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 9666-9670
    • Huang, Y.1    Yario, T.A.2    Steitz, J.A.3
  • 26
    • 0035031935 scopus 로고    scopus 로고
    • The sequence complementarity between HIV-1 5' splice site SD4 and U1 snRNA determines the steady-state level of an unstable env pre-mRNA
    • Kammler S, Leurs C, Freund M, Krummheuer J, Seidel K, Tange TO, Lund MK, Kjems J, Scheid A, Schaal H. 2001. The sequence complementarity between HIV-1 5' splice site SD4 and U1 snRNA determines the steady-state level of an unstable env pre-mRNA. RNA 7: 421-434.
    • (2001) RNA , vol.7 , pp. 421-434
    • Kammler, S.1    Leurs, C.2    Freund, M.3    Krummheuer, J.4    Seidel, K.5    Tange, T.O.6    Lund, M.K.7    Kjems, J.8    Scheid, A.9    Schaal, H.10
  • 27
    • 56749095325 scopus 로고    scopus 로고
    • Intron retention generates a novel isoform of CEACAM6 that may act as an adhesion molecule in the ectoplasmic specialization structures between spermatids and sertoli cells in rat testis
    • Kurio H, Murayama E, Kaneko T, Shibata Y, Inai T, Iida H. 2008. Intron retention generates a novel isoform of CEACAM6 that may act as an adhesion molecule in the ectoplasmic specialization structures between spermatids and sertoli cells in rat testis. Biol Reprod 79: 1062-1073.
    • (2008) Biol Reprod , vol.79 , pp. 1062-1073
    • Kurio, H.1    Murayama, E.2    Kaneko, T.3    Shibata, Y.4    Inai, T.5    Iida, H.6
  • 29
    • 19344366251 scopus 로고    scopus 로고
    • Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells
    • Lejeune F, Maquat LE. 2005. Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells. Curr Opin Cell Biol 17: 309-315.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 309-315
    • Lejeune, F.1    Maquat, L.E.2
  • 30
    • 33748635988 scopus 로고    scopus 로고
    • An intron with a constitutive transport element is retained in a Tap messenger RNA
    • Li Y, Bor YC, Misawa Y, Xue Y, Rekosh D, Hammarskjöld ML. 2006. An intron with a constitutive transport element is retained in a Tap messenger RNA. Nature 443: 234-237.
    • (2006) Nature , vol.443 , pp. 234-237
    • Li, Y.1    Bor, Y.C.2    Misawa, Y.3    Xue, Y.4    Rekosh, D.5    Hammarskjöld, M.L.6
  • 31
    • 3342991899 scopus 로고    scopus 로고
    • A novel diffuse large B-cell lymphoma-associated cancer testis antigen encoding a PAS domain protein
    • Liggins AP, Brown PJ, Asker K, Pulford K, Banham AH. 2004. A novel diffuse large B-cell lymphoma-associated cancer testis antigen encoding a PAS domain protein. Br J Cancer 91: 141-149.
    • (2004) Br J Cancer , vol.91 , pp. 141-149
    • Liggins, A.P.1    Brown, P.J.2    Asker, K.3    Pulford, K.4    Banham, A.H.5
  • 32
    • 0025169566 scopus 로고
    • U1 small nuclear RNA plays a direct role in the formation of a rev-regulated human immunodeficiency virus env mRNA that remains unspliced
    • Lu XB, Heimer J, Rekosh D, Hammarskjöld ML. 1990. U1 small nuclear RNA plays a direct role in the formation of a rev-regulated human immunodeficiency virus env mRNA that remains unspliced. Proc Natl Acad Sci 87: 7598-7602.
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 7598-7602
    • Lu, X.B.1    Heimer, J.2    Rekosh, D.3    Hammarskjöld, M.L.4
  • 33
    • 0032555951 scopus 로고    scopus 로고
    • Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage
    • Lupetti R, Pisarra P, Verrecchia A, Farina C, Nicolini G, Anichini A, Bordignon C, Sensi M, Parmiani G, Traversari C. 1998. Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage. J Exp Med 188: 1005-1016.
    • (1998) J Exp Med , vol.188 , pp. 1005-1016
    • Lupetti, R.1    Pisarra, P.2    Verrecchia, A.3    Farina, C.4    Nicolini, G.5    Anichini, A.6    Bordignon, C.7    Sensi, M.8    Parmiani, G.9    Traversari, C.10
  • 34
    • 0024518918 scopus 로고
    • The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA
    • Malim MH, Hauber J, Le SV, Maizel JV, Cullen BR. 1989. The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA. Nature 338: 254-257.
    • (1989) Nature , vol.338 , pp. 254-257
    • Malim, M.H.1    Hauber, J.2    Le, S.V.3    Maizel, J.V.4    Cullen, B.R.5
  • 35
    • 38749087964 scopus 로고    scopus 로고
    • Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins
    • Matzat LH, Berberoglu S, Levesque L. 2008. Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins. Mol Biol Cell 19: 327-338.
    • (2008) Mol Biol Cell , vol.19 , pp. 327-338
    • Matzat, L.H.1    Berberoglu, S.2    Levesque, L.3
  • 37
    • 84875229872 scopus 로고    scopus 로고
    • How cells get the message: Dynamic assembly and function of mRNA-protein complexes
    • Müller-McNicoll M, Neugebauer KM. 2013. How cells get the message: dynamic assembly and function of mRNA-protein complexes. Nat Rev Genet 14: 275-287.
    • (2013) Nat Rev Genet , vol.14 , pp. 275-287
    • Müller-McNicoll, M.1    Neugebauer, K.M.2
  • 38
    • 0035031924 scopus 로고    scopus 로고
    • Identification of a novel posttranscriptional regulatory element by using a rev- and RRE-mutated human immunodeficiency virus type 1 DNA proviral clone as a molecular trap
    • Nappi F, Schneider R, Zolotukhin A, Smulevitch S, Michalowski D, Bear J, Felber BK, Pavlakis GN. 2001. Identification of a novel posttranscriptional regulatory element by using a rev- and RRE-mutated human immunodeficiency virus type 1 DNA proviral clone as a molecular trap. J Virol 75: 4558-4569.
    • (2001) J Virol , vol.75 , pp. 4558-4569
    • Nappi, F.1    Schneider, R.2    Zolotukhin, A.3    Smulevitch, S.4    Michalowski, D.5    Bear, J.6    Felber, B.K.7    Pavlakis, G.N.8
  • 39
    • 84880964277 scopus 로고    scopus 로고
    • Postage for the messenger: Designating routes for nuclear mRNA export
    • Natalizio BJ, Wente SR. 2013. Postage for the messenger: designating routes for nuclear mRNA export. Trends Cell Biol 23: 365-373.
    • (2013) Trends Cell Biol , vol.23 , pp. 365-373
    • Natalizio, B.J.1    Wente, S.R.2
  • 42
    • 84923038882 scopus 로고
    • Identification of a constitutive transport element in the 3′ untranslated region of the Rous Sarcoma virus RNA
    • (ed. Fan H, Rein A) Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Ogert RA, Beemon KL. 1995. Identification of a constitutive transport element in the 3′ untranslated region of the Rous Sarcoma virus RNA. In Retroviruses (ed. Fan H, Rein A), p. 178. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1995) Retroviruses , pp. 178
    • Ogert, R.A.1    Beemon, K.L.2
  • 43
    • 56749098074 scopus 로고    scopus 로고
    • Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
    • Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ. 2008. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat Genet 40: 1413-1415.
    • (2008) Nat Genet , vol.40 , pp. 1413-1415
    • Pan, Q.1    Shai, O.2    Lee, L.J.3    Frey, B.J.4    Blencowe, B.J.5
  • 46
    • 0034201441 scopus 로고    scopus 로고
    • EMBOSS: The European molecular biology open software suite
    • Rice P, Longden I, Bleasby A. 2000. EMBOSS: the European molecular biology open software suite. Trends Genet 16: 276-277.
    • (2000) Trends Genet , vol.16 , pp. 276-277
    • Rice, P.1    Longden, I.2    Bleasby, A.3
  • 47
    • 84896070554 scopus 로고    scopus 로고
    • Murine leukemia virus uses NXF1 for nuclear export of spliced and unspliced viral transcripts
    • Sakuma T, Davila JI, Malcolm JA, Kocher JP, Tonne JM, Ikeda Y. 2014. Murine leukemia virus uses NXF1 for nuclear export of spliced and unspliced viral transcripts. J Virol 88: 4069-4082.
    • (2014) J Virol , vol.88 , pp. 4069-4082
    • Sakuma, T.1    Davila, J.I.2    Malcolm, J.A.3    Kocher, J.P.4    Tonne, J.M.5    Ikeda, Y.6
  • 49
    • 0027340274 scopus 로고
    • Requirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles
    • Smith AJ, Srinivasakumar N, Hammarskjöld ML, Rekosh D. 1993. Requirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles. J Virol 67: 2266-2275.
    • (1993) J Virol , vol.67 , pp. 2266-2275
    • Smith, A.J.1    Srinivasakumar, N.2    Hammarskjöld, M.L.3    Rekosh, D.4
  • 50
    • 0030738086 scopus 로고    scopus 로고
    • The effect of viral regulatory protein expression on gene delivery by human immunodeficiency virus type 1 vectors produced in stable packaging cell lines
    • Srinivasakumar N, Chazal N, Helga-Maria MC, Prasad S, Hammarskjöld ML, Rekosh D. 1997. The effect of viral regulatory protein expression on gene delivery by human immunodeficiency virus type 1 vectors produced in stable packaging cell lines. J Virol 71: 5841-5848.
    • (1997) J Virol , vol.71 , pp. 5841-5848
    • Srinivasakumar, N.1    Chazal, N.2    Helga-Maria, M.C.3    Prasad, S.4    Hammarskjöld, M.L.5    Rekosh, D.6
  • 51
    • 34547119966 scopus 로고    scopus 로고
    • The Shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a constitutive transport element
    • Swartz JE, Bor YC, Misawa Y, Rekosh D, Hammarskjöld ML. 2007. The Shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a constitutive transport element. J Biol Chem 282: 19844-19853.
    • (2007) J Biol Chem , vol.282 , pp. 19844-19853
    • Swartz, J.E.1    Bor, Y.C.2    Misawa, Y.3    Rekosh, D.4    Hammarskjöld, M.L.5
  • 54
    • 84908323329 scopus 로고    scopus 로고
    • 5th ed. University of Oregon Press, Eugene
    • Westerfield M. 2007. The zebrafish book, 5th ed. University of Oregon Press, Eugene.
    • (2007) The Zebrafish Book
    • Westerfield, M.1
  • 56
    • 84881159187 scopus 로고    scopus 로고
    • Orchestrated intron retention regulates normal granulocyte differentiation
    • Wong JW, Huang Y, Gao D, Pinello N, Gonzalez M, Baidya K, et al. 2013. Orchestrated intron retention regulates normal granulocyte differentiation. Cell 154: 583-595.
    • (2013) Cell , vol.154 , pp. 583-595
    • Wong, J.W.1    Huang, Y.2    Gao, D.3    Pinello, N.4    Gonzalez, M.5    Baidya, K.6
  • 57
    • 0032764076 scopus 로고    scopus 로고
    • Structural and functional analysis of the avian leukemia virus constitutive transport element
    • Yang J, Cullen BR. 1999. Structural and functional analysis of the avian leukemia virus constitutive transport element. RNA 5: 1645-1655.
    • (1999) RNA , vol.5 , pp. 1645-1655
    • Yang, J.1    Cullen, B.R.2
  • 58
    • 84861778204 scopus 로고    scopus 로고
    • Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention
    • Yap K, Lim ZQ, Khandelia P, Friedman B, Makeyev EV. 2012. Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention. Genes Dev 26: 1209-1223.
    • (2012) Genes Dev , vol.26 , pp. 1209-1223
    • Yap, K.1    Lim, Z.Q.2    Khandelia, P.3    Friedman, B.4    Makeyev, E.V.5
  • 59
    • 82655189968 scopus 로고    scopus 로고
    • Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1
    • Zhang ZC, Satterly N, Fontoura BM, Chook YM. 2011. Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1. Mol Biol Cell 22: 4657-4668.
    • (2011) Mol Biol Cell , vol.22 , pp. 4657-4668
    • Zhang, Z.C.1    Satterly, N.2    Fontoura, B.M.3    Chook, Y.M.4
  • 60
    • 0028033969 scopus 로고
    • Continuous propagation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian retrovirus type 1 in human peripheral blood lymphocytes
    • Zolotukhin AS, Valentin A, Pavlakis GN, Felber BK. 1994. Continuous propagation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis -acting element of simian retrovirus type 1 in human peripheral blood lymphocytes. J Virol 68: 7944-7952.
    • (1994) J Virol , vol.68 , pp. 7944-7952
    • Zolotukhin, A.S.1    Valentin, A.2    Pavlakis, G.N.3    Felber, B.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.