Using droplet-based microfluidics to improve the catalytic properties of RNA under multiple-turnover conditions

RNA

Volumn 21, Issue 3, 2015, Pages 458-469

  Ryckelynck, Michael ^a   Baudrey, Stéphanie ^a   Rick, Christian ^a   Marin, Annick ^a   Coldren, Faith ^a   Westhof, Eric ^a   Griffiths, Andrew D ^a,b  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b PSL RESEARCH UNIVERSITY   (France)

Author keywords

Droplet based microfluidics; High throughput screening; In vitro evolution; Ribozymes; RNA

Indexed keywords

DNA; PROTEIN; RIBOZYME; RNA; APTAMER;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; GENE AMPLIFICATION; GENE LIBRARY; MICROFLUIDICS; MUTAGENESIS; MUTATION RATE; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; RNA METABOLISM; RNA STRUCTURE; RNA TRANSCRIPTION; TURNOVER TIME; DIRECTED MOLECULAR EVOLUTION; GENETICS; ISOLATION AND PURIFICATION; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE;

APTAMERS, NUCLEOTIDE; DIRECTED MOLECULAR EVOLUTION; DNA; MICROFLUIDICS; RNA, CATALYTIC; SELEX APTAMER TECHNIQUE;

EID: 84923013209     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.048033.114     Document Type: Article

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