A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis

Journal of Immunological Methods

Volumn 417, Issue , 2015, Pages 34-44

  Mahan, Alison E ^a   Tedesco, Jacquelynne ^a   Dionne, Kendall ^a   Baruah, Kavitha ^b   Cheng, Hao D ^c   De Jager, Philip L ^d   Barouch, Dan H ^a,e   Suscovich, Todd ^a   Ackerman, Margaret ^c   Crispin, Max ^b   Alter, Galit ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c DARTMOUTH COLLEGE   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Capillary electrophoresis; Fc separation; Glycan analysis; IgG N glycosylation

Indexed keywords

GLYCAN; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN FC FRAGMENT; GLYCOSYLATED IGG; IMMUNOGLOBULIN G; POLYSACCHARIDE;

ANIMAL EXPERIMENT; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ARTICLE; CAPILLARY ELECTROPHORESIS; COMPLEMENT DEPOSITION; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DNA SEQUENCE; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; TUMOR IMMUNITY; VACCINATION; ANIMAL; CHEMISTRY; EVALUATION STUDY; IMMUNOLOGY; METABOLISM; PROCEDURES;

ANIMALIA;

ANIMALS; ELECTROPHORESIS, CAPILLARY; GLYCOSYLATION; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; MACACA MULATTA; MICE; POLYSACCHARIDES;

EID: 84922990828     PISSN: 00221759     EISSN: 18727905     Source Type: Journal    
DOI: 10.1016/j.jim.2014.12.004     Document Type: Article

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