Species-specific variation in glycosylation of Igc: Evidence for the species-specific sialylation and branch-specific galactosylation and importance for engineering recombinant glycoprotein therapeutics

Glycobiology

Volumn 10, Issue 5, 2000, Pages 477-486

  Raju, T Shantha ^a   Briggs, John B ^a   Borge, Steve M ^a   Jones, Andrew J S ^a  

^a GENENTECH INC   (United States)

Author keywords

Capillary electrophoresis; Carbohydrates; Glycoproteins; Glycosyltransferases; Immunoglobulins; Laser induced fluorescence detection; Mass spectrometry; Oligosaccharides; Sialic acid

Indexed keywords

GALACTOSE; GLYCOSIDASE; GLYCOSYLATED PROTEIN; IMMUNOGLOBULIN G; NEURAMINIC ACID; OLIGOSACCHARIDE; PYRENE DERIVATIVE; RECOMBINANT PROTEIN; SIALOPROTEIN;

ARTICLE; CARBOHYDRATE ANALYSIS; CAT; CHICKEN; COW; DERIVATIZATION; DOG; GEL ELECTROPHORESIS; GOAT; GUINEA PIG; HORSE; HUMAN; IMMUNOGLOBULIN STRUCTURE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; RABBIT; RHESUS MONKEY; SHEEP; SIALYLATION; SPECIES DIFFERENCE;

ANIMALIA; CANIS FAMILIARIS; CAPRA HIRCUS; CAVIA PORCELLUS; EQUUS CABALLUS; FELIS CATUS; GALLUS GALLUS; MACACA MULATTA; ORYCTOLAGUS CUNICULUS; OVIS ARIES; SUS SCROFA;

EID: 0034050074     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/10.5.477     Document Type: Article

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