Mathematical modeling of combinatorial regulation suggests that apparent positive regulation of targets by miRNA could be an artifact resulting from competition for mRNA

RNA

Volumn 21, Issue 3, 2015, Pages 307-319

  Nyayanit, Dimpal ^a,b   Gadgil, Chetan J ^a,b,c  

^a NATIONAL CHEMICAL LABORATORY   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

^c CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

Author keywords

Combinatorial binding; Mathematical model; MiRNA; Post transcriptional regulation

Indexed keywords

MESSENGER RNA; MICRORNA;

ARTICLE; ARTIFACT; BINDING COMPETITION; GENE OVEREXPRESSION; GENE REPRESSION; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; PRIORITY JOURNAL; REGULATORY MECHANISM; RNA DEGRADATION; SIMULATION; GENE EXPRESSION REGULATION; GENETICS; PROTEIN SYNTHESIS; THEORETICAL MODEL;

ARTIFACTS; GENE EXPRESSION REGULATION; MICRORNAS; MODELS, THEORETICAL; PROTEIN BIOSYNTHESIS; RNA, MESSENGER;

EID: 84922962906     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.046862.114     Document Type: Article

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