Optical imaging of COX-2: Studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor

Biochemical and Biophysical Research Communications

Volumn 458, Issue 1, 2015, Pages 40-45

  Tondera, Christoph ^a,b   Ullm, Sandra ^a,b   Laube, Markus ^a,b   Meister, Sebastian ^a   Neuber, Christin ^a   Mosch, Birgit ^a   Kniess, Torsten ^a   Pietzsch, Jens ^a,b  

^a INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Fluorescence; Luminescence; Melanoma associated inflammation; Phorbol myristate ester induced COX 2 expression; Rodent melanoma xenograft model

Indexed keywords

2 [4 (AMINOSULFONYL)PHENYL] 3 (4 METHOXYPHENYL) 1H INDOLE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; INDOLE DERIVATIVE; PHORBOL MYRISTATE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; 2-(4-(AMINOSULFONYL)PHENYL)-3-(4-METHOXYPHENYL)-1H-INDOLE; MOLECULAR PROBE; PHORBOL 13 ACETATE 12 MYRISTATE; PTGS2 PROTEIN, HUMAN; PTGS2 PROTEIN, MOUSE; SULFONAMIDE;

A375 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIARY EXCRETION; CONTROLLED STUDY; FEMALE; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; LUMINESCENCE; MELANOMA CELL; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBCUTANEOUS FAT; TUMOR XENOGRAFT; ANALYSIS; ANIMAL; CHEMISTRY; DIAGNOSTIC USE; ENZYMOLOGY; INBRED MOUSE STRAIN; MELANOMA; METABOLISM; MOLECULAR PROBE; PATHOLOGY; PROCEDURES; TUMOR CELL LINE; XENOGRAFT;

MUS; RODENTIA;

ANIMALS; CELL LINE, TUMOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; FEMALE; HETEROGRAFTS; HUMANS; INDOLES; MELANOMA; MICE, INBRED STRAINS; MOLECULAR PROBES; OPTICAL IMAGING; SULFONAMIDES; TETRADECANOYLPHORBOL ACETATE;

EID: 84922892183     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.01.057     Document Type: Article

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