메뉴 건너뛰기




Volumn 9, Issue 8, 2014, Pages

Gametocytocidal screen identifies novel chemical classes with Plasmodium falciparum transmission blocking activity

Author keywords

[No Author keywords available]

Indexed keywords

ACETOMENAPHTHONE; ANASTROZOLE; ANAZOLENE SODIUM; ANTIMONY TARTRATE; ANTIPROTOZOAL AGENT; BENZALKONIUM CHLORIDE; BENZETHONIUM CHLORIDE; CETALKONIUM CHLORIDE; CETYLPYRIDINIUM SALT; CLOTRIMAZOLE; CRYSTAL VIOLET; DITHIAZANINE IODIDE; ETHIDIUM BROMIDE; IFOSFAMIDE; MAPROTILINE; MEGESTROL ACETATE; MELPHALAN; METHYLBENZETHONIUM CHLORIDE; PENTAMIDINE; PENTANOL; PRIMAQUINE; PYRITHIONE ZINC; PYRVINIUM EMBONATE; TILORONE; TONZONIUM BROMIDE; ACRIDINE DERIVATIVE; ANTIMALARIAL AGENT; QUATERNARY AMMONIUM DERIVATIVE;

EID: 84922827862     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0105817     Document Type: Article
Times cited : (43)

References (48)
  • 1
    • 84856679687 scopus 로고    scopus 로고
    • Global malaria mortality between 1980 and 2010: A systematic analysis
    • Murray CJL, Rosenfeld LC, Lim SS, Andrews KG, Foreman KJ, et al. (2012) Global malaria mortality between 1980 and 2010: a systematic analysis. Lancet 379: 413-431.
    • (2012) Lancet , vol.379 , pp. 413-431
    • Murray, C.J.L.1    Rosenfeld, L.C.2    Lim, S.S.3    Andrews, K.G.4    Foreman, K.J.5
  • 2
    • 79951617726 scopus 로고    scopus 로고
    • A research agenda for malaria eradication: Vector control
    • License A, Malaria G, Program E (2011) A research agenda for malaria eradication: vector control. PLoS Med 8: e1000401.
    • (2011) PLoS Med , vol.8
    • License, A.1    Malaria, G.2    Program, E.3
  • 4
    • 84871529294 scopus 로고    scopus 로고
    • Sustainable malaria control: Transdisciplinary approaches for translational applications
    • Birkholtz L-M, Bornman R, Focke W, Mutero C, de Jager C (2012) Sustainable malaria control: transdisciplinary approaches for translational applications. Malar J 11: 431.
    • (2012) Malar J , vol.11 , pp. 431
    • Birkholtz, L.-M.1    Bornman, R.2    Focke, W.3    Mutero, C.4    De Jager, C.5
  • 5
    • 80054715187 scopus 로고    scopus 로고
    • A high-throughput assay for the identification of drugs against late-stage Plasmodium falciparum gametocytes
    • Peatey CL, Spicer TP, Hodder PS, Trenholme KR, Gardiner DL (2011) A high-throughput assay for the identification of drugs against late-stage Plasmodium falciparum gametocytes. Mol Biochem Parasitol 180: 127-131.
    • (2011) Mol Biochem Parasitol , vol.180 , pp. 127-131
    • Peatey, C.L.1    Spicer, T.P.2    Hodder, P.S.3    Trenholme, K.R.4    Gardiner, D.L.5
  • 6
    • 84882580906 scopus 로고    scopus 로고
    • A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection
    • D'Alessandro S, Silvestrini F, Dechering K, Corbett Y, Parapini S, et al. (2013) A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection. J Antimicrob Chemother 68 (9): 2048-2058.
    • (2013) J Antimicrob Chemother , vol.68 , Issue.9 , pp. 2048-2058
    • D'Alessandro, S.1    Silvestrini, F.2    Dechering, K.3    Corbett, Y.4    Parapini, S.5
  • 7
    • 79953868333 scopus 로고    scopus 로고
    • A malaria gametocytocidal assay using oxidoreduction indicator, alamarBlue
    • Tanaka TQ, Williamson KC (2011) A malaria gametocytocidal assay using oxidoreduction indicator, alamarBlue. Mol Biochem Parasitol 177: 160-163.
    • (2011) Mol Biochem Parasitol , vol.177 , pp. 160-163
    • Tanaka, T.Q.1    Williamson, K.C.2
  • 8
    • 84859728437 scopus 로고    scopus 로고
    • Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence "transmission blocking" assay
    • Lelièvre J, Almela MJ, Lozano S, Miguel C, Franco V, et al. (2012) Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence "transmission blocking" assay. PLoS One 7: e35019.
    • (2012) PLoS One , vol.7
    • Lelièvre, J.1    Almela, M.J.2    Lozano, S.3    Miguel, C.4    Franco, V.5
  • 9
    • 82755197376 scopus 로고    scopus 로고
    • Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue
    • Adjalley SH, Johnston GL, Li T, Eastman RT, Ekland EH, et al. (2011) Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue. Proc Natl Acad Sci U S A 108: E1214-23.
    • (2011) Proc Natl Acad Sci U S a , vol.108
    • Adjalley, S.H.1    Johnston, G.L.2    Li, T.3    Eastman, R.T.4    Ekland, E.H.5
  • 10
    • 84906754009 scopus 로고    scopus 로고
    • Chemical signatures and new drug targets for gametocytocidal drug development
    • Sun W, Tanaka TQ, Magle CT, Huang W, Southall N, et al. (2014) Chemical signatures and new drug targets for gametocytocidal drug development. Sci Rep 4: 3743.
    • (2014) Sci Rep , vol.4 , pp. 3743
    • Sun, W.1    Tanaka, T.Q.2    Magle, C.T.3    Huang, W.4    Southall, N.5
  • 12
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • DOI 10.1177/108705719900400206
    • Zhang J-H, Chung TDY, Oldenburg KR (1999) A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J Biomol Screen 4: 67-73. (Pubitemid 29278954)
    • (1999) Journal of Biomolecular Screening , vol.4 , Issue.2 , pp. 67-73
    • Zhang, J.-H.1    Chung, T.D.Y.2    Oldenburg, K.R.3
  • 14
    • 84887200907 scopus 로고    scopus 로고
    • Identification of inhibitors of Plasmodium falciparum gametocyte development
    • Duffy S, Avery VM (2013) Identification of inhibitors of Plasmodium falciparum gametocyte development. Malar J 12: 408.
    • (2013) Malar J , vol.12 , pp. 408
    • Duffy, S.1    Avery, V.M.2
  • 15
    • 84893487091 scopus 로고    scopus 로고
    • Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the Malaria Box
    • Bowman JD, Merino EF, Brooks CF, Striepen B, Carlier PR, et al. (2013) Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the Malaria Box. Antimicrob Agents Chemother 58: 811- 819.
    • (2013) Antimicrob Agents Chemother , vol.58 , pp. 811-819
    • Bowman, J.D.1    Merino, E.F.2    Brooks, C.F.3    Striepen, B.4    Carlier, P.R.5
  • 16
    • 84887436357 scopus 로고    scopus 로고
    • Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay
    • Lucantoni L, Duffy S, Adjalley SH, Fidock DA, Avery VM (2013) Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay. Antimicrob Agents Chemother 57: 6050-6062.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 6050-6062
    • Lucantoni, L.1    Duffy, S.2    Adjalley, S.H.3    Fidock, D.A.4    Avery, V.M.5
  • 17
    • 77953027026 scopus 로고    scopus 로고
    • Malaria gametocytogenesis
    • Baker DA (2010) Malaria gametocytogenesis. Mol Biochem Parasitol 172: 57-65.
    • (2010) Mol Biochem Parasitol , vol.172 , pp. 57-65
    • Baker, D.A.1
  • 18
    • 84879082233 scopus 로고    scopus 로고
    • The metabolism of primaquine to its active metabolite is dependent on CYP 2D6
    • Pybus BS, Marcsisin SR, Jin X, Deye G, Sousa JC, et al. (2013) The metabolism of primaquine to its active metabolite is dependent on CYP 2D6. Malar J 12: 1.
    • (2013) Malar J , vol.12 , pp. 1
    • Pybus, B.S.1    Marcsisin, S.R.2    Jin, X.3    Deye, G.4    Sousa, J.C.5
  • 19
    • 50949100870 scopus 로고    scopus 로고
    • Efficacy of pyrvinium pamoate against Cryptosporidium parvum infection in vitro and in a neonatal mouse model
    • Downey AS, Chong CR, Graczyk TK, Sullivan DJ (2008) Efficacy of pyrvinium pamoate against Cryptosporidium parvum infection in vitro and in a neonatal mouse model. Antimicrob Agents Chemother 52: 3106-3112.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 3106-3112
    • Downey, A.S.1    Chong, C.R.2    Graczyk, T.K.3    Sullivan, D.J.4
  • 20
    • 33746381549 scopus 로고    scopus 로고
    • A clinical drug library screen identifies astemizole as an antimalarial agent
    • DOI 10.1038/nchembio806, PII NCHEMBIO806
    • Chong CR, Chen X, Shi L, Liu JO, Sullivan DJ (2006) A clinical drug library screen identifies astemizole as an antimalarial agent. Nat Chem Biol 2: 415-416. (Pubitemid 44114918)
    • (2006) Nature Chemical Biology , vol.2 , Issue.8 , pp. 415-416
    • Chong, C.R.1    Chen, X.2    Shi, L.3    Liu, J.O.4    Sullivan Jr., D.J.5
  • 21
    • 84864432128 scopus 로고    scopus 로고
    • An anticancer agent, pyrvinium pamoate inhibits the NADH-fumarate reductase system - A unique mitochondrial energy metabolism in tumour microenvironments
    • Tomitsuka E, Kita K, Esumi H (2012) An anticancer agent, pyrvinium pamoate inhibits the NADH-fumarate reductase system-a unique mitochondrial energy metabolism in tumour microenvironments. J Biochem 152: 171-183.
    • (2012) J Biochem , vol.152 , pp. 171-183
    • Tomitsuka, E.1    Kita, K.2    Esumi, H.3
  • 22
    • 84881452814 scopus 로고    scopus 로고
    • Novel conjugated quinoline-indoles compromise Plasmodium falciparum mitochondrial function and show promising antimalarial activity
    • Teguh SC, Klonis N, Duffy S, Lucantoni L, Avery VM, et al. (2013) Novel conjugated quinoline-indoles compromise Plasmodium falciparum mitochondrial function and show promising antimalarial activity. J Med Chem 56: 6200-6215.
    • (2013) J Med Chem , vol.56 , pp. 6200-6215
    • Teguh, S.C.1    Klonis, N.2    Duffy, S.3    Lucantoni, L.4    Avery, V.M.5
  • 23
    • 67649817177 scopus 로고    scopus 로고
    • Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: A randomised controlled trial
    • Coulibaly B, Zoungrana A, Mockenhaupt FP, Schirmer RH, Klose C, et al. (2009) Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial. PLoS One 4: e5318.
    • (2009) PLoS One , vol.4
    • Coulibaly, B.1    Zoungrana, A.2    Mockenhaupt, F.P.3    Schirmer, R.H.4    Klose, C.5
  • 24
    • 79955526843 scopus 로고    scopus 로고
    • In vitro activity of Proveblue (methylene blue) on Plasmodium falciparum strains resistant to standard antimalarial drugs
    • Pascual A, Henry M, Briolant S, Charras S, Baret E, et al. (2011) In vitro activity of Proveblue (methylene blue) on Plasmodium falciparum strains resistant to standard antimalarial drugs. Antimicrob Agents Chemother 55: 2472-2474.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 2472-2474
    • Pascual, A.1    Henry, M.2    Briolant, S.3    Charras, S.4    Baret, E.5
  • 25
    • 84876133924 scopus 로고    scopus 로고
    • Impact of methylene blue and atorvastatin combination therapy on the apparition of cerebral malaria in a murine model
    • Dormoi J, Briolant S, Desgrouas C, Pradines B (2013) Impact of methylene blue and atorvastatin combination therapy on the apparition of cerebral malaria in a murine model. Malar J 12: 127.
    • (2013) Malar J , vol.12 , pp. 127
    • Dormoi, J.1    Briolant, S.2    Desgrouas, C.3    Pradines, B.4
  • 26
    • 84879028216 scopus 로고    scopus 로고
    • Efficacy of proveblue (methylene blue) in an experimental cerebral malaria murine model
    • Dormoi J, Briolant S, Desgrouas C, Pradines B (2013) Efficacy of proveblue (methylene blue) in an experimental cerebral malaria murine model. Antimicrob Agents Chemother 57: 3412-3414.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 3412-3414
    • Dormoi, J.1    Briolant, S.2    Desgrouas, C.3    Pradines, B.4
  • 27
    • 73049164053 scopus 로고
    • Quaternary ammonium compounds in medicinal chemistry I
    • D'Arcy PF, Taylor EP (1962) Quaternary ammonium compounds in medicinal chemistry I. J Pharm Pharmacol 14: 129-146.
    • (1962) J Pharm Pharmacol , vol.14 , pp. 129-146
    • D'Arcy, P.F.1    Taylor, E.P.2
  • 28
    • 0242473502 scopus 로고
    • Quaternary ammonium compounds in medicinal chemistry II
    • D'Arcy PF, Taylor EP (1962) Quaternary ammonium compounds in medicinal chemistry II. J Pharm Pharmacol 14: 193-216.
    • (1962) J Pharm Pharmacol , vol.14 , pp. 193-216
    • D'Arcy, P.F.1    Taylor, E.P.2
  • 29
    • 84873783512 scopus 로고
    • Chemotherapeutic Properties of Some New Quaternary Ammonium Compounds; Their Cesticidal Action Against Hymenolepis Nana
    • Bhattacharya BK, Sen AB (1965) Chemotherapeutic Properties of Some New Quaternary Ammonium Compounds; Their Cesticidal Action Against Hymenolepis Nana. Br J Pharmacol Chemother 24: 240-244.
    • (1965) Br J Pharmacol Chemother , vol.24 , pp. 240-244
    • Bhattacharya, B.K.1    Sen, A.B.2
  • 31
    • 84867610036 scopus 로고    scopus 로고
    • Miltefosine: A review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis
    • Dorlo TPC, Balasegaram M, Beijnen JH, de Vries PJ (2012) Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis. J Antimicrob Chemother 67: 2576-2597.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 2576-2597
    • Dorlo, T.P.C.1    Balasegaram, M.2    Beijnen, J.H.3    De Vries, P.J.4
  • 33
    • 84555177934 scopus 로고    scopus 로고
    • Quaternary ammonium salts and their antimicrobial potential: Targets or nonspecific interactions?
    • Tischer M, Pradel G, Ohlsen K, Holzgrabe U (2012) Quaternary ammonium salts and their antimicrobial potential: targets or nonspecific interactions? Chem Med Chem 7: 22-31.
    • (2012) Chem Med Chem , vol.7 , pp. 22-31
    • Tischer, M.1    Pradel, G.2    Ohlsen, K.3    Holzgrabe, U.4
  • 34
    • 0030725087 scopus 로고    scopus 로고
    • Antimalarial activity of molecules interfering with Plasmodium falciparum phospholipid metabolism. Structure-activity relationship analysis
    • DOI 10.1021/jm9701886
    • Calas M, Cordina G, Bompart J, Ben Bari M, Jei T, et al. (1997) Antimalarial activity of molecules interfering with Plasmodium falciparum phospholipid metabolism. Structure-activity relationship analysis. J Med Chem 40: 3557-3566. (Pubitemid 27465088)
    • (1997) Journal of Medicinal Chemistry , vol.40 , Issue.22 , pp. 3557-3566
    • Calas, M.1    Cordina, G.2    Bompart, J.3    Bari, M.B.4    Jei, T.5    Ancelin, M.L.6    Vial, H.7
  • 35
    • 84887302542 scopus 로고    scopus 로고
    • Plasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission
    • Bobenchik A (2013) Plasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission. Proc Natl Acad Sci 110: 18262-18267.
    • (2013) Proc Natl Acad Sci , vol.110 , pp. 18262-18267
    • Bobenchik, A.1
  • 36
    • 84864486652 scopus 로고    scopus 로고
    • Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate
    • Wein S, Maynadier M, Bordat Y, Perez J, Maheshwari S, et al. (2012) Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate. Br J Pharmacol 166: 2263-2276.
    • (2012) Br J Pharmacol , vol.166 , pp. 2263-2276
    • Wein, S.1    Maynadier, M.2    Bordat, Y.3    Perez, J.4    Maheshwari, S.5
  • 37
    • 84940350612 scopus 로고    scopus 로고
    • (n.d.). Available: Accessed 2014 Jul15
    • Drugs.com Maprotiline Dosage (n.d.). Available: http://www.drugs.com/ dosage/maprotiline.html. Accessed 2014 Jul15.
    • Drugs.Com Maprotiline Dosage
  • 38
    • 84940314197 scopus 로고    scopus 로고
    • (n.d.). Available: Accessed 2014 Jul 15
    • Drug Bank: Maprotiline (n.d.). Available: http://www.drugbank.ca/drugs/ DB00934. Accessed 2014 Jul 15.
    • Maprotiline
  • 39
    • 80455131069 scopus 로고    scopus 로고
    • Acridine and Acridinones: Old and New Structures with Antimalarial Activity
    • Valdés AF (2011) Acridine and Acridinones: Old and New Structures with Antimalarial Activity. Open Med Chem J 5: 11-20.
    • (2011) Open Med Chem J , vol.5 , pp. 11-20
    • Valdés, A.F.1
  • 40
    • 84859196773 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of acridine derivatives as antimalarial agents
    • Yu X-M, Ramiandrasoa F, Guetzoyan L, Pradines B, Quintino E, et al. (2012) Synthesis and biological evaluation of acridine derivatives as antimalarial agents. Chem Med Chem 7: 587-605.
    • (2012) Chem Med Chem , vol.7 , pp. 587-605
    • Yu, X.-M.1    Ramiandrasoa, F.2    Guetzoyan, L.3    Pradines, B.4    Quintino, E.5
  • 42
    • 72149093269 scopus 로고    scopus 로고
    • Antimalarial acridines: Synthesis, in vitro activity against P. Falciparum and interaction with hematin
    • Guetzoyan L, Yu X-M, Ramiandrasoa F, Pethe S, Rogier C, et al. (2009) Antimalarial acridines: synthesis, in vitro activity against P. falciparum and interaction with hematin. Bioorg Med Chem 17: 8032-8039.
    • (2009) Bioorg Med Chem , vol.17 , pp. 8032-8039
    • Guetzoyan, L.1    Yu, X.-M.2    Ramiandrasoa, F.3    Pethe, S.4    Rogier, C.5
  • 45
    • 0034620614 scopus 로고    scopus 로고
    • Gametocytocidal activity of pyronaridine and DNA topoisomerase II inhibitors against multidrug-resistant Plasmodium falciparum in vitro
    • DOI 10.1016/S1383-5769(99)00028-8, PII S1383576999000288
    • Chavalitshewinkoon-Petmitr P, Pongvilairat G (2000) Gametocytocidal activity of pyronaridine and DNA topoisomerase II inhibitors against multidrug-resistant Plasmodium falciparum in vitro. Parasitol Int. 48(4): 275-80. (Pubitemid 30145444)
    • (2000) Parasitology International , vol.48 , Issue.4 , pp. 275-280
    • Chavalitshewinkoon-Petmitr, P.1    Pongvilairat, G.2    Auparakkitanon, S.3    Wilairat, P.4
  • 46
    • 0034673530 scopus 로고    scopus 로고
    • Cleavage of DNA induced by 9-anilinoacridine inhibitors of topoisomerase II in the malaria parasite Plasmodium falciparum
    • DOI 10.1006/bbrc.2000.2305
    • Auparakkitanon S, Wilairat P (2000) Cleavage of DNA induced by 9-anilinoacridine inhibitors of topoisomerase II in the malaria parasite Plasmodium falciparum. Biochem Biophys Res Commun 269: 406-409. (Pubitemid 30440313)
    • (2000) Biochemical and Biophysical Research Communications , vol.269 , Issue.2 , pp. 406-409
    • Auparakkitanon, S.1    Wilairat, P.2
  • 47
    • 84940320722 scopus 로고    scopus 로고
    • (n.d.). Available: Accessed 2013 Aug 5
    • Collaborative Drug Discovery (n.d.). Available: https://www. collaborativedrug.com/. Accessed 2013 Aug 5.
  • 48
    • 84872040862 scopus 로고    scopus 로고
    • A Class of Tricyclic Compounds Blocking Malaria Parasite Oocyst
    • doi:10.1128/AAC.00920-12
    • Eastman RT, Pattaradilokrat S, Raj DK, Dixit S, Deng B, et al. (2013) A Class of Tricyclic Compounds Blocking Malaria Parasite Oocyst. Antimicrob Agents Chemother 57 (1): 425-535. doi:10.1128/AAC.00920-12.
    • (2013) Antimicrob Agents Chemother , vol.57 , Issue.1 , pp. 425-535
    • Eastman, R.T.1    Pattaradilokrat, S.2    Raj, D.K.3    Dixit, S.4    Deng, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.