Biomechanical stability of novel mechanically adapted open-porous titanium scaffolds in metatarsal bone defects of sheep

Biomaterials

Volumn 46, Issue , 2015, Pages 35-47

  Wieding, Jan ^a   Lindner, Tobias ^a   Bergschmidt, Philipp ^a   Bader, Rainer ^a  

^a ROSTOCK UNIVERSITY MEDICAL CENTER   (Germany)

Author keywords

Invivo; Metatarsus; Open porous titanium scaffolds; Segmental defects; Sheep; Torsional testing

Indexed keywords

ALUMINUM ALLOYS; BIOMECHANICS; DEFECTS; ELASTIC MODULI; PORE SIZE; SHEAR STRAIN; SHEAR STRESS; STIFFNESS; TERNARY ALLOYS; TITANIUM ALLOYS; VANADIUM ALLOYS;

IN-VIVO; METATARSUS; POROUS TITANIUM; SEGMENTAL DEFECTS; SHEEP; TORSIONAL TESTING;

SCAFFOLDS;

TITANIUM; TITANIUM ALLOY (TIAL6V4);

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMECHANICS; BONE DEFECT; BONE DENSITY; BONE PLATE; CONTROLLED STUDY; DIAPHYSIS; EXPERIMENTAL STUDY; FEMALE; MECHANICAL TORSION; METATARSAL BONE; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; SHEAR STRENGTH; SHEAR STRESS; TORQUE; YOUNG MODULUS; ANIMAL; BONE DEVELOPMENT; BONE MINERALIZATION; CHEMISTRY; DRUG EFFECTS; FRACTURE; IMPLANT; LASER; MATERIALS TESTING; PATHOLOGY; PATHOPHYSIOLOGY; POROSITY; RADIOGRAPHY; SHEEP; TISSUE SCAFFOLD;

OVIS ARIES;

ANIMALS; BIOMECHANICAL PHENOMENA; BONE DENSITY; CALCIFICATION, PHYSIOLOGIC; FEMALE; FRACTURES, BONE; IMPLANTS, EXPERIMENTAL; LASERS; MATERIALS TESTING; METATARSAL BONES; OSTEOGENESIS; POROSITY; SHEEP; TISSUE SCAFFOLDS; TITANIUM;

EID: 84922820763     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.12.010     Document Type: Article

References (58)

1. Rueger J.M. [Bone substitution materials. Current status and prospects]. Orthopade 1998 Feb, 27(2):72-79.
2. Schieker M., Heiss C., Mutschler W. [Bone substitutes]. Unfallchirurg 2008 Aug, 111(8):613-619.
3. Grob D. Problems at the donor site in autologous bone transplantation. Unfallchirurg 1986, 89(8):339-345.
4. Banwart J.C., Asher M.A., Hassanein R.S. Iliac crest bone graft harvest donor site morbidity. A statistical evaluation. Spine (Phila Pa 1976 ) 1995 May 1, 20(9):1055-1060.
5. Wippermann B.W., Schratt H.E., Steeg S., Tscherne H. [Complications of spongiosa harvesting of the ilial crest. A retrospective analysis of 1,191 cases]. Chirurg 1997 Dec, 68(12):1286-1291.
6. Bloemers F.W., Blokhuis T.J., Patka P., Bakker F.C., Wippermann B.W., Haarman H.J. Autologous bone versus calcium-phosphate ceramics in treatment of experimental bone defects. JBiomed Mater Res B Appl Biomater 2003 Aug 15, 66(2):526-531.
7. Field J.R., McGee M., Wildenauer C., Kurmis A., Margerrison E. The utilization of a synthetic bone void filler (JAX) in the repair of a femoral segmental defect. Vet Comp Orthop Traumatol 2009, 22(2):87-95.
8. Mastrogiacomo M., Corsi A., Francioso E., Di C.M., Monetti F., Scaglione S., et al. Reconstruction of extensive long bone defects in sheep using resorbable bioceramics based on silicon stabilized tricalcium phosphate. Tissue Eng 2006 May, 12(5):1261-1273.
9. Schneiders W., Reinstorf A., Biewener A., Serra A., Grass R., Kinscher M., et al. Invivo effects of modification of hydroxyapatite/collagen composites with and without chondroitin sulphate on bone remodeling in the sheep tibia. JOrthop Res 2009 Jan, 27(1):15-21.
10. Tyllianakis M., Deligianni D., Panagopoulos A., Pappas M., Sourgiadaki E., Mavrilas D., et al. Biomechanical comparison of callus over a locked intramedullary nail in various segmental bone defects in a sheep model. Med Sci Monit 2007 May, 13(5):BR125-BR130.
11. Viateau V., Guillemin G., Bousson V., Oudina K., Hannouche D., Sedel L., et al. Long-bone critical-size defects treated with tissue-engineered grafts: a study on sheep. JOrthop Res 2007 Jun, 25(6):741-749.
12. Sarkar M.R., Augat P., Shefelbine S.J., Schorlemmer S., Huber-Lang M., Claes L., et al. Bone formation in a long bone defect model using a platelet-rich plasma-loaded collagen scaffold. Biomaterials 2006 Mar, 27(9):1817-1823.
13. Blokhuis T.J., Wippermann B.W., Den Boer F.C., van Lingen A., Patka P., Bakker F.C., et al. Resorbable calcium phosphate particles as a carrier material for bone marrow in an ovine segmental defect. JBiomed Mater Res 2000 Sep 5, 51(3):369-375.
14. Sciadini M.F., Dawson J.M., Johnson K.D. Evaluation of bovine-derived bone protein with a natural coral carrier as a bone-graft substitute in a canine segmental defect model. JOrthop Res 1997 Nov, 15(6):844-857.
15. Gierse H., Donath K. Reactions and complications after the implantation of endobon including morphological examination of explants. Arch Orthop Trauma Surg 1999, 119(5-6):349-355.
16. Linhart W., Briem D., Amling M., Rueger J.M., Windolf J. [Mechanical failure of porous hydroxyapatite ceramics 7.5 years after implantation in the proximal tibial]. Unfallchirurg 2004 Feb, 107(2):154-157.
17. Marcacci M., Kon E., Zaffagnini S., Giardino R., Rocca M., Corsi A., et al. Reconstruction of extensive long-bone defects in sheep using porous hydroxyapatite sponges. Calcif Tissue Int 1999 Jan, 64(1):83-90.
18. Attias N., Lindsey R.W. Case reports: management of large segmental tibial defects using a cylindrical mesh cage. Clin Orthop Relat Res 2006 Sep, 450:259-266.
19. Cobos J.A., Lindsey R.W., Gugala Z. The cylindrical titanium mesh cage for treatment of a long bone segmental defect: description of a new technique and report of two cases. JOrthop Trauma 2000 Jan, 14(1):54-59.
20. Ostermann P.A., Haase N., Rubberdt A., Wich M., Ekkernkamp A. Management of a long segmental defect at the proximal meta-diaphyseal junction of the tibia using a cylindrical titanium mesh cage. JOrthop Trauma 2002 Sep, 16(8):597-601.
21. Heck D.A., Chao E.Y., Sim F.H., Pritchard D.J., Shives T.C. Titanium fibermetal segmental replacement prostheses. A radiographic analysis and review of current status. Clin Orthop Relat Res 1986 Mar, (204):266-285.
22. Wieding J., Jonitz A., Bader R. The effect of structural design on mechanical properties and cellular response of additive manufactured titanium scaffolds. Mater 2012, 5(8):1336-1347.
23. Jonitz-Heincke A., Wieding J., Schulze C., Hansmann D., Bader R. Comparative analysis of the oxygen supply and viability of human osteoblasts in three-dimensional titanium scaffolds produced by laser-beam or electron-beam melting. Mater 2013, 6(11):5398-5409.
24. Murakami N., Saito N., Horiuchi H., Okada T., Nozaki K., Takaoka K. Repair of segmental defects in rabbit humeri with titanium fiber mesh cylinders containing recombinant human bone morphogenetic protein-2 (rhBMP-2) and a synthetic polymer. JBiomed Mater Res 2002 Nov, 62(2):169-174.
25. Ponader S., von W.C., Widenmayer M., Lutz R., Heinl P., Koerner C., et al. Invivo performance of selective electron beam-melted Ti-6Al-4V structures. JBiomed Mater Res A 2010 Jan, 92(1):56-62.
26. Lopez-Heredia M.A., Goyenvalle E., Aguado E., Pilet P., Leroux C., Dorget M., et al. Bone growth in rapid prototyped porous titanium implants. JBiomed Mater Res A 2008 Jun 1, 85(3):664-673.
27. van R.B., Huiskes R. Load transfer and stress shielding of the hydroxyapatite-ABG hip: a study of stem length and proximal fixation. JArthroplasty 2001 Dec, 16(8 Suppl.1):55-63.
28. Niinomi M., Nakai M. Titanium-based biomaterials for preventing stress shielding between implant devices and bone. Int J Biomater 2011, 2011:836587.
29. Antonialli A.I.S., Bolfarini C. Numerical evaluation of reduction of stress shielding in laser coated hip prostheses. Mater Res-Ibero-Am J Mater 2011 Jul, 14(3):331-334.
30. Murr L.E., Gaytan S.M., Medina F., Lopez H., Martinez E., Machado B.I., et al. Next-generation biomedical implants using additive manufacturing of complex, cellular and functional mesh arrays. Philos Trans A Math Phys Eng Sci 2010 Apr 28, 368(1917):1999-2032.
31. Parthasarathy J., Starly B., Raman S., Christensen A. Mechanical evaluation of porous titanium (Ti6Al4V) structures with electron beam melting (EBM). JMech Behav Biomed Mater 2010 Apr, 3(3):249-259.
32. Schwerdtfeger J., Heinl P., Singer R.F., Koerner C. Auxetic cellular structures through selective electron-beam melting. Phys Status Solidi B-Basic Solid State Phys 2010 Feb, 247(2):269-272.
33. Li J.P., Habibovic P., van den Doel M., Wilson C.E., de Wijn J.R., van Blitterswijk C.A., et al. Bone ingrowth in porous titanium implants produced by 3D fiber deposition. Biomaterials 2007 Jun, 28(18):2810-2820.
34. van der Stok J., Wang H., Amin Y.S., Siebelt M., Sandker M., Waarsing J.H., et al. Enhanced bone regeneration of cortical segmental bone defects using porous titanium scaffolds incorporated with colloidal gelatin gels for time- and dose-controlled delivery of dual growth factors. Tissue Eng Part 2013 Aug, 19(23-14):2605-2614.
35. Okada Y., Suka T., Sim F.H., Gorski J.P., Chao E.Y. Comparison of replacement prostheses for segmental defects of bone. Different porous coatings for extracortical fixation. JBone Jt Surg Am 1988 Feb, 70(2):160-172.
36. Andersson G.B., Galante J.O., Rostoker W. Segmental replacement of the femur in baboons. Comparison of fixation through bone ingrowth with and without methylmethacrylate. Arch Orthop Trauma Surg 1981, 99(1):47-51.
37. Heck D.A., Nakajima I., Kelly P.J., Chao E.Y. The effect of load alteration on the biological and biomechanical performance of a titanium fiber-metal segmental prosthesis. JBone Jt Surg Am 1986 Jan, 68(1):118-126.
38. Wieding J., Souffrant R., Mittelmeier W., Bader R. Finite element analysis on the biomechanical stability of open porous titanium scaffolds for large segmental bone defects under physiological load conditions. Med Eng Phys 2013 Apr 10, 35(4):422-432.
39. Wieding J., Souffrant R., Mittelmeier W., Bader R. Acurve-shaped flexible mesh cage for treatment of large segmental bone defects - a finite element analysis. Biomed Tech Berl 2012, 57(Suppl.1):825-828.
40. Royer P., Rey C. Calcium phosphate coatings for orthopaedic prosthesis. Surf Coat Technol 1991, 45(1-3):171-177.
41. Szmukler-Moncler S., Perrin D., Ahossi V., Pointaire P. Evaluation of BONIT, a fully resorbable CaP coating obtained by electrochemical deposition, after 6 weeks of healing: a pilot study in the pig maxilla. Key Eng Mat 2001, 192-195:395-398. Uetikon-Zuerich, Switzerland.
42. Turner C.H., Burr D.B. Basic biomechanical measurements of bone - a tutorial. Bone 1993 Jul, 14(4):595-608.
43. Athanasiou K.A., Zhu C.F., Lanctot D.R., Agrawal C.M., Wang X. Fundamentals of biomechanics in tissue engineering of bone. Tissue Eng 2000 Aug, 6(4):361-381.
44. Nazarian A., Hermannsson B.J., Muller J., Zurakowski D., Snyder B.D. Effects of tissue preservation on murine bone mechanical properties. JBiomech 2009 Jan 5, 42(1):82-86.
45. O'Neill K.R., Stutz C.M., Mignemi N.A., Burns M.C., Murry M.R., Nyman J.S., et al. Micro-computed tomography assessment of the progression of fracture healing in mice. Bone 2012 Jun, 50(6):1357-1367.
46. Engesaeter L.B., Ekeland A., Langeland N. Methods for testing the mechanical properties of the rat femur. Acta Orthop Scand 1978 Dec, 49(6):512-518.
47. Horner E.A., Kirkham J., Wood D., Curran S., Smith M., Thomson B., et al. Long bone defect models for tissue engineering applications: criteria for choice. Tissue Eng Part B Rev 2010 Apr, 16(2):263-271.
48. Liebschner M.A.K. Biomechanical considerations of animal models used in tissue engineering of bone. Biomaterials 2004 Apr, 25(9):1697-1714.
49. Reichert J.C., Saifzadeh S., Wullschleger M.E., Epari D.R., Schutz M.A., Duda G.N., et al. The challenge of establishing preclinical models for segmental bone defect research. Biomaterials 2009 Apr, 30(12):2149-2163.
50. Gao T.J., Lindholm T.S., Kommonen B., Ragni P., Paronzini A., Lindholm T.C., et al. The use of a coral composite implant containing bone morphogenetic protein to repair a segmental tibial defect in sheep. Int Orthop 1997, 21(3):194-200.
51. Habibovic P., Kruyt M.C., Juhl M.V., Clyens S., Martinetti R., Dolcini L., et al. Comparative invivo study of six hydroxyapatite-based bone graft substitutes. JOrthop Res 2008 Oct, 26(10):1363-1370.
52. Ohman C., Baleani M., Pani C., Taddei F., Alberghini M., Viceconti M., et al. Compressive behaviour of child and adult cortical bone. Bone 2011 Oct, 49(4):769-776.
53. Reichert J.C., Wullschleger M.E., Cipitria A., Lienau J., Cheng T.K., Schutz M.A., et al. Custom-made composite scaffolds for segmental defect repair in long bones. Int Orthop 2011 Dec, 35(8):1229-1236.
54. Lill C.A., Hesseln J., Schlegel U., Eckhardt C., Goldhahn J., Schneider E. Biomechanical evaluation of healing in a non-critical defect in a large animal model of osteoporosis. JOrthop Res 2003 Sep, 21(5):836-842.
55. Schonberger T., Kasten P., Fechner K., Sudkamp N.P., Pearce S., Niemeyer P. [Novel software-based and validated evaluation method for objective quantification of bone regeneration in experimental bone defects]. ZOrthop Unf 2010 Jan, 148(1):19-25.
56. Topp T., Muller T., Huss S., Kann P.H., Weihe E., Ruchholtz S., et al. Embalmed and fresh frozen human bones in orthopedic cadaveric studies: which bone is authentic and feasible?. Acta Orthop 2012 Oct, 83(5):543-547.
57. Unger S., Blauth M., Schmoelz W. Effects of three different preservation methods on the mechanical properties of human and bovine cortical bone. Bone 2010 Dec, 47(6):1048-1053.
58. Wieding J., Wolf A., Bader R. Numerical optimization of open-porous bone scaffold structures to match the elastic properties of human cortical bone. JMech Behav Biomed Mater 2014 Sep, 37(0):56-68.