메뉴 건너뛰기




Volumn 30, Issue 12, 2009, Pages 2149-2163

The challenge of establishing preclinical models for segmental bone defect research

Author keywords

Animal models; Bone defects; Bone engineering; Orthopaedic research; Preclinical studies

Indexed keywords

ANIMAL MODELS; BONE DEFECTS; BONE ENGINEERING; ORTHOPAEDIC RESEARCH; PRECLINICAL STUDIES;

EID: 60849106318     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.12.050     Document Type: Article
Times cited : (359)

References (160)
  • 1
    • 0034073485 scopus 로고    scopus 로고
    • Segmental bone repair by tissue-engineered periosteal cell transplants with bioresorbable fleece and fibrin scaffolds in rabbits
    • Perka C., Schultz O., Spitzer R.S., Lindenhayn K., Burmester G.R., and Sittinger M. Segmental bone repair by tissue-engineered periosteal cell transplants with bioresorbable fleece and fibrin scaffolds in rabbits. Biomaterials 21 11 (2000) 1145-1153
    • (2000) Biomaterials , vol.21 , Issue.11 , pp. 1145-1153
    • Perka, C.1    Schultz, O.2    Spitzer, R.S.3    Lindenhayn, K.4    Burmester, G.R.5    Sittinger, M.6
  • 2
    • 33745251044 scopus 로고    scopus 로고
    • Repair of segmental bone defects in rabbit tibiae using a complex of beta-tricalcium phosphate, type I collagen, and fibroblast growth factor-2
    • Komaki H., Tanaka T., Chazono M., and Kikuchi T. Repair of segmental bone defects in rabbit tibiae using a complex of beta-tricalcium phosphate, type I collagen, and fibroblast growth factor-2. Biomaterials 27 29 (2006) 5118-5126
    • (2006) Biomaterials , vol.27 , Issue.29 , pp. 5118-5126
    • Komaki, H.1    Tanaka, T.2    Chazono, M.3    Kikuchi, T.4
  • 3
    • 0036342774 scopus 로고    scopus 로고
    • Healing of critical-size segmental bone defects in the sheep tibiae using bioresorbable polylactide membranes
    • Gugala Z., and Gogolewski S. Healing of critical-size segmental bone defects in the sheep tibiae using bioresorbable polylactide membranes. Injury 33 Suppl. 2 (2002) B71-B76
    • (2002) Injury , vol.33 , Issue.SUPPL. 2
    • Gugala, Z.1    Gogolewski, S.2
  • 4
    • 0038743203 scopus 로고    scopus 로고
    • Healing of segmental bone defects with granular porous hydroxyapatite augmented with recombinant human osteogenic protein-1 or autologous bone marrow
    • den Boer F.C., Wippermann B.W., Blokhuis T.J., Patka P., Bakker F.C., and Haarman H.J. Healing of segmental bone defects with granular porous hydroxyapatite augmented with recombinant human osteogenic protein-1 or autologous bone marrow. J Orthop Res 21 3 (2003) 521-528
    • (2003) J Orthop Res , vol.21 , Issue.3 , pp. 521-528
    • den Boer, F.C.1    Wippermann, B.W.2    Blokhuis, T.J.3    Patka, P.4    Bakker, F.C.5    Haarman, H.J.6
  • 6
    • 34247630256 scopus 로고    scopus 로고
    • Quantification of growth factors in allogenic bone grafts extracted with three different methods
    • Wildemann B., Kadow-Romacker A., Pruss A., Haas N.P., and Schmidmaier G. Quantification of growth factors in allogenic bone grafts extracted with three different methods. Cell Tissue Bank 8 2 (2007) 107-114
    • (2007) Cell Tissue Bank , vol.8 , Issue.2 , pp. 107-114
    • Wildemann, B.1    Kadow-Romacker, A.2    Pruss, A.3    Haas, N.P.4    Schmidmaier, G.5
  • 7
    • 0033065993 scopus 로고    scopus 로고
    • Bone repair techniques, bone graft, and bone graft substitutes
    • Perry C.R. Bone repair techniques, bone graft, and bone graft substitutes. Clin Orthop Relat Res 360 (1999) 71-86
    • (1999) Clin Orthop Relat Res , vol.360 , pp. 71-86
    • Perry, C.R.1
  • 10
    • 27744432259 scopus 로고    scopus 로고
    • Tissue regeneration. The past, the present and the future
    • Giannoudis P.V., and Pountos I. Tissue regeneration. The past, the present and the future. Injury 36 Suppl. 4 (2005) S2-S5
    • (2005) Injury , vol.36 , Issue.SUPPL. 4
    • Giannoudis, P.V.1    Pountos, I.2
  • 12
    • 0021347256 scopus 로고
    • The healing of segmental bone defects induced by demineralized bone matrix. A radiographic and biomechanical study
    • Einhorn T.A., Lane J.M., Burstein A.H., Kopman C.R., and Vigorita V.J. The healing of segmental bone defects induced by demineralized bone matrix. A radiographic and biomechanical study. J Bone Joint Surg Am 66 2 (1984) 274-279
    • (1984) J Bone Joint Surg Am , vol.66 , Issue.2 , pp. 274-279
    • Einhorn, T.A.1    Lane, J.M.2    Burstein, A.H.3    Kopman, C.R.4    Vigorita, V.J.5
  • 13
    • 41649115258 scopus 로고    scopus 로고
    • Repair of goat tibial defects with bone marrow stromal cells and beta-tricalcium phosphate
    • Liu G., Zhao L., Zhang W., Cui L., Liu W., and Cao Y. Repair of goat tibial defects with bone marrow stromal cells and beta-tricalcium phosphate. J Mater Sci Mater Med 19 6 (2008) 2367-2376
    • (2008) J Mater Sci Mater Med , vol.19 , Issue.6 , pp. 2367-2376
    • Liu, G.1    Zhao, L.2    Zhang, W.3    Cui, L.4    Liu, W.5    Cao, Y.6
  • 14
    • 0034609623 scopus 로고    scopus 로고
    • Resorbable calcium phosphate particles as a carrier material for bone marrow in an ovine segmental defect
    • Blokhuis T.J., Wippermann B.W., den Boer F.C., van Lingen A., Patka P., Bakker F.C., et al. Resorbable calcium phosphate particles as a carrier material for bone marrow in an ovine segmental defect. J Biomed Mater Res 51 3 (2000) 369-375
    • (2000) J Biomed Mater Res , vol.51 , Issue.3 , pp. 369-375
    • Blokhuis, T.J.1    Wippermann, B.W.2    den Boer, F.C.3    van Lingen, A.4    Patka, P.5    Bakker, F.C.6
  • 15
    • 0030560782 scopus 로고    scopus 로고
    • Enhanced healing of segmental tibial defects in sheep by a composite bone substitute composed of tricalcium phosphate cylinder, bone morphogenetic protein, and type IV collagen
    • Gao T.J., Lindholm T.S., Kommonen B., Ragni P., Paronzini A., Lindholm T.C., et al. Enhanced healing of segmental tibial defects in sheep by a composite bone substitute composed of tricalcium phosphate cylinder, bone morphogenetic protein, and type IV collagen. J Biomed Mater Res 32 4 (1996) 505-512
    • (1996) J Biomed Mater Res , vol.32 , Issue.4 , pp. 505-512
    • Gao, T.J.1    Lindholm, T.S.2    Kommonen, B.3    Ragni, P.4    Paronzini, A.5    Lindholm, T.C.6
  • 16
    • 38649133324 scopus 로고    scopus 로고
    • Reconstruction of tibia defects by ipsilateral vascularized fibula transposition
    • Theos C., Koulouvaris P., Kottakis S., and Demertzis N. Reconstruction of tibia defects by ipsilateral vascularized fibula transposition. Arch Orthop Trauma Surg 128 2 (2008) 179-184
    • (2008) Arch Orthop Trauma Surg , vol.128 , Issue.2 , pp. 179-184
    • Theos, C.1    Koulouvaris, P.2    Kottakis, S.3    Demertzis, N.4
  • 18
    • 0024514289 scopus 로고
    • Interporous hydroxyapatite as a bone graft substitute in tibial plateau fractures
    • Bucholz R.W., Carlton A., and Holmes R. Interporous hydroxyapatite as a bone graft substitute in tibial plateau fractures. Clin Orthop Relat Res 240 (1989) 53-62
    • (1989) Clin Orthop Relat Res , vol.240 , pp. 53-62
    • Bucholz, R.W.1    Carlton, A.2    Holmes, R.3
  • 19
    • 34447253328 scopus 로고    scopus 로고
    • Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects
    • Oest M.E., Dupont K.M., Kong H.J., Mooney D.J., and Guldberg R.E. Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects. J Orthop Res 25 7 (2007) 941-950
    • (2007) J Orthop Res , vol.25 , Issue.7 , pp. 941-950
    • Oest, M.E.1    Dupont, K.M.2    Kong, H.J.3    Mooney, D.J.4    Guldberg, R.E.5
  • 20
    • 0031735030 scopus 로고    scopus 로고
    • Enhancement of fracture healing with autogenous and allogeneic bone grafts
    • Stevenson S. Enhancement of fracture healing with autogenous and allogeneic bone grafts. Clin Orthop Relat Res 355 Suppl. (1998) S239-S246
    • (1998) Clin Orthop Relat Res , Issue.355 SUPPL
    • Stevenson, S.1
  • 21
    • 0031278010 scopus 로고    scopus 로고
    • Evaluation of bovine-derived bone protein with a natural coral carrier as a bone-graft substitute in a canine segmental defect model
    • Sciadini M.F., Dawson J.M., and Johnson K.D. Evaluation of bovine-derived bone protein with a natural coral carrier as a bone-graft substitute in a canine segmental defect model. J Orthop Res 15 6 (1997) 844-857
    • (1997) J Orthop Res , vol.15 , Issue.6 , pp. 844-857
    • Sciadini, M.F.1    Dawson, J.M.2    Johnson, K.D.3
  • 22
    • 0024377022 scopus 로고
    • Morbidity at bone graft donor sites
    • Younger E.M., and Chapman M.W. Morbidity at bone graft donor sites. J Orthop Trauma 3 3 (1989) 192-195
    • (1989) J Orthop Trauma , vol.3 , Issue.3 , pp. 192-195
    • Younger, E.M.1    Chapman, M.W.2
  • 23
    • 0016782384 scopus 로고
    • The free vascularized bone graft. A clinical extension of microvascular techniques
    • Taylor G.I., Miller G.D., and Ham F.J. The free vascularized bone graft. A clinical extension of microvascular techniques. Plast Reconstr Surg 55 5 (1975) 533-544
    • (1975) Plast Reconstr Surg , vol.55 , Issue.5 , pp. 533-544
    • Taylor, G.I.1    Miller, G.D.2    Ham, F.J.3
  • 24
    • 0022004216 scopus 로고
    • A roentgenographic, biomechanical, and histological evaluation of vascularized and non-vascularized segmental fibular canine autografts
    • Dell P.C., Burchardt H., and Glowczewskie Jr. F.P. A roentgenographic, biomechanical, and histological evaluation of vascularized and non-vascularized segmental fibular canine autografts. J Bone Joint Surg Am 67 1 (1985) 105-112
    • (1985) J Bone Joint Surg Am , vol.67 , Issue.1 , pp. 105-112
    • Dell, P.C.1    Burchardt, H.2    Glowczewskie Jr., F.P.3
  • 25
    • 33746163549 scopus 로고    scopus 로고
    • The efficacy of cylindrical titanium mesh cage for the reconstruction of a critical-size canine segmental femoral diaphyseal defect
    • Lindsey R.W., Gugala Z., Milne E., Sun M., Gannon F.H., and Latta L.L. The efficacy of cylindrical titanium mesh cage for the reconstruction of a critical-size canine segmental femoral diaphyseal defect. J Orthop Res 24 7 (2006) 1438-1453
    • (2006) J Orthop Res , vol.24 , Issue.7 , pp. 1438-1453
    • Lindsey, R.W.1    Gugala, Z.2    Milne, E.3    Sun, M.4    Gannon, F.H.5    Latta, L.L.6
  • 27
    • 0002474157 scopus 로고
    • Alternatives to autogenous bone graft: efficacy and indications
    • Gazdag A.R., Lane J.M., Glaser D., and Forster R.A. Alternatives to autogenous bone graft: efficacy and indications. J Am Acad Orthop Surg 3 1 (1995) 1-8
    • (1995) J Am Acad Orthop Surg , vol.3 , Issue.1 , pp. 1-8
    • Gazdag, A.R.1    Lane, J.M.2    Glaser, D.3    Forster, R.A.4
  • 29
    • 0030930156 scopus 로고    scopus 로고
    • Treatment of acute fractures with a collagen-calcium phosphate graft material. A randomized clinical trial
    • Chapman M.W., Bucholz R., and Cornell C. Treatment of acute fractures with a collagen-calcium phosphate graft material. A randomized clinical trial. J Bone Joint Surg Am 79 4 (1997) 495-502
    • (1997) J Bone Joint Surg Am , vol.79 , Issue.4 , pp. 495-502
    • Chapman, M.W.1    Bucholz, R.2    Cornell, C.3
  • 31
    • 0028217327 scopus 로고
    • Segmental tibial defects. Comparing conventional and Ilizarov methodologies
    • Cierny III G., and Zorn K.E. Segmental tibial defects. Comparing conventional and Ilizarov methodologies. Clin Orthop Relat Res 301 (1994) 118-123
    • (1994) Clin Orthop Relat Res , vol.301 , pp. 118-123
    • Cierny III, G.1    Zorn, K.E.2
  • 32
    • 0024505048 scopus 로고
    • The tension-stress effect on the genesis and growth of tissues: part II. The influence of the rate and frequency of distraction
    • Ilizarov G.A. The tension-stress effect on the genesis and growth of tissues: part II. The influence of the rate and frequency of distraction. Clin Orthop Relat Res 239 (1989) 263-285
    • (1989) Clin Orthop Relat Res , vol.239 , pp. 263-285
    • Ilizarov, G.A.1
  • 33
    • 0021365425 scopus 로고
    • The results of 39 fractures complicated by major segmental bone loss and/or leg length discrepancy
    • Goldstrohm G.L., Mears D.C., and Swartz W.M. The results of 39 fractures complicated by major segmental bone loss and/or leg length discrepancy. J Trauma 24 1 (1984) 50-58
    • (1984) J Trauma , vol.24 , Issue.1 , pp. 50-58
    • Goldstrohm, G.L.1    Mears, D.C.2    Swartz, W.M.3
  • 34
    • 34547943315 scopus 로고    scopus 로고
    • New Approaches in the treatment of critical-size segmental defects in long bones
    • Gugala Z., Lindsey R.W., and Gogolewski S. New Approaches in the treatment of critical-size segmental defects in long bones. Macromol Symp 253 (2007) 147-161
    • (2007) Macromol Symp , vol.253 , pp. 147-161
    • Gugala, Z.1    Lindsey, R.W.2    Gogolewski, S.3
  • 35
    • 0032751167 scopus 로고    scopus 로고
    • Clinically applied models of bone regeneration in tissue engineering research
    • Einhorn T.A. Clinically applied models of bone regeneration in tissue engineering research. Clin Orthop Relat Res 367 Suppl. (1999) S59-S67
    • (1999) Clin Orthop Relat Res , Issue.367 SUPPL
    • Einhorn, T.A.1
  • 37
    • 0033087970 scopus 로고    scopus 로고
    • Regeneration of segmental diaphyseal defects in sheep tibiae using resorbable polymeric membranes: a preliminary study
    • Gugala Z., and Gogolewski S. Regeneration of segmental diaphyseal defects in sheep tibiae using resorbable polymeric membranes: a preliminary study. J Orthop Trauma 13 3 (1999) 187-195
    • (1999) J Orthop Trauma , vol.13 , Issue.3 , pp. 187-195
    • Gugala, Z.1    Gogolewski, S.2
  • 38
    • 40149086690 scopus 로고    scopus 로고
    • Nonunions and the potential of stem cells in fracture-healing
    • Tseng S.S., Lee M.A., and Reddi A.H. Nonunions and the potential of stem cells in fracture-healing. J Bone Joint Surg Am 90 Suppl. 1 (2008) 92-98
    • (2008) J Bone Joint Surg Am , vol.90 , Issue.SUPPL. 1 , pp. 92-98
    • Tseng, S.S.1    Lee, M.A.2    Reddi, A.H.3
  • 39
    • 26944488042 scopus 로고    scopus 로고
    • Animal models for fracture treatment in osteoporosis
    • Egermann M., Goldhahn J., and Schneider E. Animal models for fracture treatment in osteoporosis. Osteoporos Int 16 Suppl. 2 (2005) S129-S138
    • (2005) Osteoporos Int , vol.16 , Issue.SUPPL. 2
    • Egermann, M.1    Goldhahn, J.2    Schneider, E.3
  • 40
    • 0347753912 scopus 로고    scopus 로고
    • Biomechanical considerations of animal models used in tissue engineering of bone
    • Liebschner M.A. Biomechanical considerations of animal models used in tissue engineering of bone. Biomaterials 25 9 (2004) 1697-1714
    • (2004) Biomaterials , vol.25 , Issue.9 , pp. 1697-1714
    • Liebschner, M.A.1
  • 41
    • 0027992696 scopus 로고
    • Spine update. The use of animal models to study spinal fusion
    • Schimandle J.H., and Boden S.D. Spine update. The use of animal models to study spinal fusion. Spine 19 17 (1994) 1998-2006
    • (1994) Spine , vol.19 , Issue.17 , pp. 1998-2006
    • Schimandle, J.H.1    Boden, S.D.2
  • 43
    • 0034821559 scopus 로고    scopus 로고
    • Sheep model in orthopedic research: a literature review
    • Martini L., Fini M., Giavaresi G., and Giardino R. Sheep model in orthopedic research: a literature review. Comp Med 51 4 (2001) 292-299
    • (2001) Comp Med , vol.51 , Issue.4 , pp. 292-299
    • Martini, L.1    Fini, M.2    Giavaresi, G.3    Giardino, R.4
  • 44
    • 0031763862 scopus 로고    scopus 로고
    • Interspecies differences in bone composition, density, and quality: potential implications for in vivo bone research
    • Aerssens J., Boonen S., Lowet G., and Dequeker J. Interspecies differences in bone composition, density, and quality: potential implications for in vivo bone research. Endocrinology 139 2 (1998) 663-670
    • (1998) Endocrinology , vol.139 , Issue.2 , pp. 663-670
    • Aerssens, J.1    Boonen, S.2    Lowet, G.3    Dequeker, J.4
  • 45
    • 0000906182 scopus 로고
    • The density of organic and volatile and non-volatile inorganic components of bone
    • Gong J.K., Arnold J.S., and Cohn S.H. The density of organic and volatile and non-volatile inorganic components of bone. Anat Rec 149 (1964) 319-324
    • (1964) Anat Rec , vol.149 , pp. 319-324
    • Gong, J.K.1    Arnold, J.S.2    Cohn, S.H.3
  • 46
    • 0032465631 scopus 로고    scopus 로고
    • An interspecies comparison of bone fracture properties
    • Wang X., Mabrey J.D., and Agrawal C.M. An interspecies comparison of bone fracture properties. Biomed Mater Eng 8 1 (1998) 1-9
    • (1998) Biomed Mater Eng , vol.8 , Issue.1 , pp. 1-9
    • Wang, X.1    Mabrey, J.D.2    Agrawal, C.M.3
  • 47
    • 0027657468 scopus 로고
    • Comparison of human and canine external femoral morphologies in the context of total hip replacement
    • Bloebaum R.D., Ota D.T., Skedros J.G., and Mantas J.P. Comparison of human and canine external femoral morphologies in the context of total hip replacement. J Biomed Mater Res 27 9 (1993) 1149-1159
    • (1993) J Biomed Mater Res , vol.27 , Issue.9 , pp. 1149-1159
    • Bloebaum, R.D.1    Ota, D.T.2    Skedros, J.G.3    Mantas, J.P.4
  • 48
    • 0032247356 scopus 로고    scopus 로고
    • Use of animal models in musculoskeletal research
    • Neyt J.G., Buckwalter J.A., and Carroll N.C. Use of animal models in musculoskeletal research. Iowa Orthop J 18 (1998) 118-123
    • (1998) Iowa Orthop J , vol.18 , pp. 118-123
    • Neyt, J.G.1    Buckwalter, J.A.2    Carroll, N.C.3
  • 49
    • 40149090336 scopus 로고    scopus 로고
    • Selection and development of preclinical models in fracture-healing research
    • O'Loughlin P.F., Morr S., Bogunovic L., Kim A.D., Park B., and Lane J.M. Selection and development of preclinical models in fracture-healing research. J Bone Joint Surg Am 90 Suppl. 1 (2008) 79-84
    • (2008) J Bone Joint Surg Am , vol.90 , Issue.SUPPL. 1 , pp. 79-84
    • O'Loughlin, P.F.1    Morr, S.2    Bogunovic, L.3    Kim, A.D.4    Park, B.5    Lane, J.M.6
  • 50
    • 0029147322 scopus 로고
    • The potential of sheep for the study of osteopenia: current status and comparison with other animal models
    • Newman E., Turner A.S., and Wark J.D. The potential of sheep for the study of osteopenia: current status and comparison with other animal models. Bone 16 4 Suppl. (1995) 277S-284S
    • (1995) Bone , vol.16 , Issue.4 SUPPL
    • Newman, E.1    Turner, A.S.2    Wark, J.D.3
  • 51
    • 21844468932 scopus 로고    scopus 로고
    • On the influence of soft tissue coverage in the determination of bone kinematics using skin markers
    • Taylor W.R., Ehrig R.M., Duda G.N., Schell H., Seebeck P., and Heller M.O. On the influence of soft tissue coverage in the determination of bone kinematics using skin markers. J Orthop Res 23 4 (2005) 726-734
    • (2005) J Orthop Res , vol.23 , Issue.4 , pp. 726-734
    • Taylor, W.R.1    Ehrig, R.M.2    Duda, G.N.3    Schell, H.4    Seebeck, P.5    Heller, M.O.6
  • 55
    • 0033197576 scopus 로고    scopus 로고
    • New segmental long bone defect model in sheep: quantitative analysis of healing with dual energy x-ray absorptiometry
    • den Boer F.C., Patka P., Bakker F.C., Wippermann B.W., van Lingen A., Vink G.Q., et al. New segmental long bone defect model in sheep: quantitative analysis of healing with dual energy x-ray absorptiometry. J Orthop Res 17 5 (1999) 654-660
    • (1999) J Orthop Res , vol.17 , Issue.5 , pp. 654-660
    • den Boer, F.C.1    Patka, P.2    Bakker, F.C.3    Wippermann, B.W.4    van Lingen, A.5    Vink, G.Q.6
  • 56
    • 34250016026 scopus 로고    scopus 로고
    • Development of bone
    • Sumner-Smith G. (Ed), W.B. Saunders Co., Philadelphia
    • de Kleer V. Development of bone. In: Sumner-Smith G. (Ed). Bone in clinical orthopedics (2006), W.B. Saunders Co., Philadelphia 1-80
    • (2006) Bone in clinical orthopedics , pp. 1-80
    • de Kleer, V.1
  • 57
    • 0019865454 scopus 로고
    • Bone regeneration in animals and in man. A contribution to understanding the relative value of animal experiments to human pathophysiology
    • Eitel F., Klapp F., Jacobson W., and Schweiberer L. Bone regeneration in animals and in man. A contribution to understanding the relative value of animal experiments to human pathophysiology. Arch Orthop Trauma Surg 99 1 (1981) 59-64
    • (1981) Arch Orthop Trauma Surg , vol.99 , Issue.1 , pp. 59-64
    • Eitel, F.1    Klapp, F.2    Jacobson, W.3    Schweiberer, L.4
  • 58
    • 0033855870 scopus 로고    scopus 로고
    • Properties of growing trabecular ovine bone. Part I: mechanical and physical properties
    • Nafei A., Danielsen C.C., Linde F., and Hvid I. Properties of growing trabecular ovine bone. Part I: mechanical and physical properties. J Bone Joint Surg Br 82 6 (2000) 910-920
    • (2000) J Bone Joint Surg Br , vol.82 , Issue.6 , pp. 910-920
    • Nafei, A.1    Danielsen, C.C.2    Linde, F.3    Hvid, I.4
  • 59
    • 27144471318 scopus 로고    scopus 로고
    • Repairing of goat tibial bone defects with BMP-2 gene-modified tissue-engineered bone
    • Dai K.R., Xu X.L., Tang T.T., Zhu Z.A., Yu C.F., Lou J.R., et al. Repairing of goat tibial bone defects with BMP-2 gene-modified tissue-engineered bone. Calcif Tissue Int 77 1 (2005) 55-61
    • (2005) Calcif Tissue Int , vol.77 , Issue.1 , pp. 55-61
    • Dai, K.R.1    Xu, X.L.2    Tang, T.T.3    Zhu, Z.A.4    Yu, C.F.5    Lou, J.R.6
  • 60
    • 0027286258 scopus 로고
    • Calcium-restricted ovariectomized Sinclair S-1 minipigs: an animal model of osteopenia and trabecular plate perforation
    • Mosekilde L., Weisbrode S.E., Safron J.A., Stills H.F., Jankowsky M.L., Ebert D.C., et al. Calcium-restricted ovariectomized Sinclair S-1 minipigs: an animal model of osteopenia and trabecular plate perforation. Bone 14 3 (1993) 379-382
    • (1993) Bone , vol.14 , Issue.3 , pp. 379-382
    • Mosekilde, L.1    Weisbrode, S.E.2    Safron, J.A.3    Stills, H.F.4    Jankowsky, M.L.5    Ebert, D.C.6
  • 62
    • 0023816122 scopus 로고
    • A device for producing experimental fractures
    • Macdonald W., Skirving A.P., and Scull E.R. A device for producing experimental fractures. Acta Orthop Scand 59 5 (1988) 542-544
    • (1988) Acta Orthop Scand , vol.59 , Issue.5 , pp. 542-544
    • Macdonald, W.1    Skirving, A.P.2    Scull, E.R.3
  • 63
    • 0023510856 scopus 로고
    • Carbon fiber reinforced plastic (CFRP) plates versus stainless steel dynamic compression plates in the treatment of fractures of the tibiae in dogs
    • Skirving A.P., Day R., Macdonald W., and McLaren R. Carbon fiber reinforced plastic (CFRP) plates versus stainless steel dynamic compression plates in the treatment of fractures of the tibiae in dogs. Clin Orthop Relat Res 224 (1987) 117-124
    • (1987) Clin Orthop Relat Res , vol.224 , pp. 117-124
    • Skirving, A.P.1    Day, R.2    Macdonald, W.3    McLaren, R.4
  • 64
    • 0030061854 scopus 로고    scopus 로고
    • Soft-tissue blood flow following reamed versus unreamed locked intramedullary nailing: a fractured sheep tibia model
    • Schemitsch E.H., Kowalski M.J., and Swiontkowski M.F. Soft-tissue blood flow following reamed versus unreamed locked intramedullary nailing: a fractured sheep tibia model. Ann Plast Surg 36 1 (1996) 70-75
    • (1996) Ann Plast Surg , vol.36 , Issue.1 , pp. 70-75
    • Schemitsch, E.H.1    Kowalski, M.J.2    Swiontkowski, M.F.3
  • 65
    • 0028528922 scopus 로고
    • Cortical bone blood flow in reamed and unreamed locked intramedullary nailing: a fractured tibia model in sheep
    • Schemitsch E.H., Kowalski M.J., Swiontkowski M.F., and Senft D. Cortical bone blood flow in reamed and unreamed locked intramedullary nailing: a fractured tibia model in sheep. J Orthop Trauma 8 5 (1994) 373-382
    • (1994) J Orthop Trauma , vol.8 , Issue.5 , pp. 373-382
    • Schemitsch, E.H.1    Kowalski, M.J.2    Swiontkowski, M.F.3    Senft, D.4
  • 66
    • 0030636125 scopus 로고    scopus 로고
    • Strength recovery in fractured sheep tibia treated with a plate or an internal fixator: an experimental study with a two-year follow-up
    • Tepic S., Remiger A.R., Morikawa K., Predieri M., and Perren S.M. Strength recovery in fractured sheep tibia treated with a plate or an internal fixator: an experimental study with a two-year follow-up. J Orthop Trauma 11 1 (1997) 14-23
    • (1997) J Orthop Trauma , vol.11 , Issue.1 , pp. 14-23
    • Tepic, S.1    Remiger, A.R.2    Morikawa, K.3    Predieri, M.4    Perren, S.M.5
  • 67
    • 0024672098 scopus 로고
    • The effect of external fixation stiffness on early healing of transverse osteotomies
    • Gilbert J.A., Dahners L.E., and Atkinson M.A. The effect of external fixation stiffness on early healing of transverse osteotomies. J Orthop Res 7 3 (1989) 389-397
    • (1989) J Orthop Res , vol.7 , Issue.3 , pp. 389-397
    • Gilbert, J.A.1    Dahners, L.E.2    Atkinson, M.A.3
  • 69
    • 0025514082 scopus 로고
    • A study of fracture callus material properties: relationship to the torsional strength of bone
    • Markel M.D., Wikenheiser M.A., and Chao E.Y. A study of fracture callus material properties: relationship to the torsional strength of bone. J Orthop Res 8 6 (1990) 843-850
    • (1990) J Orthop Res , vol.8 , Issue.6 , pp. 843-850
    • Markel, M.D.1    Wikenheiser, M.A.2    Chao, E.Y.3
  • 70
    • 33847392077 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 in absorbable collagen sponge enhances bone healing of tibial osteotomies in dogs
    • Faria M.L., Lu Y., Heaney K., Uthamanthil R.K., Muir P., and Markel M.D. Recombinant human bone morphogenetic protein-2 in absorbable collagen sponge enhances bone healing of tibial osteotomies in dogs. Vet Surg 36 2 (2007) 122-131
    • (2007) Vet Surg , vol.36 , Issue.2 , pp. 122-131
    • Faria, M.L.1    Lu, Y.2    Heaney, K.3    Uthamanthil, R.K.4    Muir, P.5    Markel, M.D.6
  • 71
    • 3142530591 scopus 로고    scopus 로고
    • Percutaneous injection of recombinant human bone morphogenetic protein-2 in a calcium phosphate paste accelerates healing of a canine tibial osteotomy
    • Edwards III R.B., Seeherman H.J., Bogdanske J.J., Devitt J., Vanderby Jr. R., and Markel M.D. Percutaneous injection of recombinant human bone morphogenetic protein-2 in a calcium phosphate paste accelerates healing of a canine tibial osteotomy. J Bone Joint Surg Am 86-A 7 (2004) 1425-1438
    • (2004) J Bone Joint Surg Am , vol.86 -A , Issue.7 , pp. 1425-1438
    • Edwards III, R.B.1    Seeherman, H.J.2    Bogdanske, J.J.3    Devitt, J.4    Vanderby Jr., R.5    Markel, M.D.6
  • 72
    • 0034981441 scopus 로고    scopus 로고
    • Effect of shock wave therapy on acute fractures of the tibia: a study in a dog model
    • Wang C.J., Huang H.Y., Chen H.H., Pai C.H., and Yang K.D. Effect of shock wave therapy on acute fractures of the tibia: a study in a dog model. Clin Orthop Relat Res 387 (2001) 112-118
    • (2001) Clin Orthop Relat Res , vol.387 , pp. 112-118
    • Wang, C.J.1    Huang, H.Y.2    Chen, H.H.3    Pai, C.H.4    Yang, K.D.5
  • 73
    • 0035219313 scopus 로고    scopus 로고
    • Effect of unreamed, limited reamed, and standard reamed intramedullary nailing on cortical bone porosity and new bone formation
    • Hupel T.M., Weinberg J.A., Aksenov S.A., and Schemitsch E.H. Effect of unreamed, limited reamed, and standard reamed intramedullary nailing on cortical bone porosity and new bone formation. J Orthop Trauma 15 1 (2001) 18-27
    • (2001) J Orthop Trauma , vol.15 , Issue.1 , pp. 18-27
    • Hupel, T.M.1    Weinberg, J.A.2    Aksenov, S.A.3    Schemitsch, E.H.4
  • 74
    • 0033087361 scopus 로고    scopus 로고
    • Influence of plate design on cortical bone perfusion and fracture healing in canine segmental tibial fractures
    • Jain R., Podworny N., Hupel T.M., Weinberg J., and Schemitsch E.H. Influence of plate design on cortical bone perfusion and fracture healing in canine segmental tibial fractures. J Orthop Trauma 13 3 (1999) 178-186
    • (1999) J Orthop Trauma , vol.13 , Issue.3 , pp. 178-186
    • Jain, R.1    Podworny, N.2    Hupel, T.M.3    Weinberg, J.4    Schemitsch, E.H.5
  • 75
    • 0031781483 scopus 로고    scopus 로고
    • Recombinant human basic fibroblast growth factor accelerates fracture healing by enhancing callus remodeling in experimental dog tibial fracture
    • Nakamura T., Hara Y., Tagawa M., Tamura M., Yuge T., Fukuda H., et al. Recombinant human basic fibroblast growth factor accelerates fracture healing by enhancing callus remodeling in experimental dog tibial fracture. J Bone Miner Res 13 6 (1998) 942-949
    • (1998) J Bone Miner Res , vol.13 , Issue.6 , pp. 942-949
    • Nakamura, T.1    Hara, Y.2    Tagawa, M.3    Tamura, M.4    Yuge, T.5    Fukuda, H.6
  • 76
    • 0025364049 scopus 로고
    • The significance of postoperative stability for osseous repair of a multiple fragment fracture. Animal experiment studies
    • Heitemeyer U., Claes L., and Hierholzer G. The significance of postoperative stability for osseous repair of a multiple fragment fracture. Animal experiment studies. Unfallchirurg 93 2 (1990) 49-55
    • (1990) Unfallchirurg , vol.93 , Issue.2 , pp. 49-55
    • Heitemeyer, U.1    Claes, L.2    Hierholzer, G.3
  • 77
    • 0027657623 scopus 로고
    • The role of fixator frame stiffness in the control of fracture healing. An experimental study
    • Goodship A.E., Watkins P.E., Rigby H.S., and Kenwright J. The role of fixator frame stiffness in the control of fracture healing. An experimental study. J Biomech 26 9 (1993) 1027-1035
    • (1993) J Biomech , vol.26 , Issue.9 , pp. 1027-1035
    • Goodship, A.E.1    Watkins, P.E.2    Rigby, H.S.3    Kenwright, J.4
  • 78
    • 0029201013 scopus 로고
    • Measurement of serum angiogenic factor in devascularized experimental tibial fractures
    • Wallace A.L., Makki R., Weiss J.B., and Hughes S.P. Measurement of serum angiogenic factor in devascularized experimental tibial fractures. J Orthop Trauma 9 4 (1995) 324-332
    • (1995) J Orthop Trauma , vol.9 , Issue.4 , pp. 324-332
    • Wallace, A.L.1    Makki, R.2    Weiss, J.B.3    Hughes, S.P.4
  • 79
    • 0031032220 scopus 로고    scopus 로고
    • Quantitative assessment of experimental fracture repair by peripheral computed tomography
    • Augat P., Merk J., Genant H.K., and Claes L. Quantitative assessment of experimental fracture repair by peripheral computed tomography. Calcif Tissue Int 60 2 (1997) 194-199
    • (1997) Calcif Tissue Int , vol.60 , Issue.2 , pp. 194-199
    • Augat, P.1    Merk, J.2    Genant, H.K.3    Claes, L.4
  • 80
    • 0142179142 scopus 로고    scopus 로고
    • Shear movement at the fracture site delays healing in a diaphyseal fracture model
    • Augat P., Burger J., Schorlemmer S., Henke T., Peraus M., and Claes L. Shear movement at the fracture site delays healing in a diaphyseal fracture model. J Orthop Res 21 6 (2003) 1011-1017
    • (2003) J Orthop Res , vol.21 , Issue.6 , pp. 1011-1017
    • Augat, P.1    Burger, J.2    Schorlemmer, S.3    Henke, T.4    Peraus, M.5    Claes, L.6
  • 81
    • 22544481349 scopus 로고    scopus 로고
    • The course of bone healing is influenced by the initial shear fixation stability
    • Schell H., Epari D.R., Kassi J.P., Bragulla H., Bail H.J., and Duda G.N. The course of bone healing is influenced by the initial shear fixation stability. J Orthop Res 23 5 (2005) 1022-1028
    • (2005) J Orthop Res , vol.23 , Issue.5 , pp. 1022-1028
    • Schell, H.1    Epari, D.R.2    Kassi, J.P.3    Bragulla, H.4    Bail, H.J.5    Duda, G.N.6
  • 82
    • 33749394690 scopus 로고    scopus 로고
    • Instability prolongs the chondral phase during bone healing in sheep
    • Epari D.R., Schell H., Bail H.J., and Duda G.N. Instability prolongs the chondral phase during bone healing in sheep. Bone 38 6 (2006) 864-870
    • (2006) Bone , vol.38 , Issue.6 , pp. 864-870
    • Epari, D.R.1    Schell, H.2    Bail, H.J.3    Duda, G.N.4
  • 83
    • 18344400282 scopus 로고    scopus 로고
    • Fracture healing of the sheep tibia treated using a unilateral external fixator. Comparison of static and dynamic fixation
    • Hente R., Cordey J., Rahn B.A., Maghsudi M., von Gumppenberg S., and Perren S.M. Fracture healing of the sheep tibia treated using a unilateral external fixator. Comparison of static and dynamic fixation. Injury 30 Suppl. 1 (1999) A44-A51
    • (1999) Injury , vol.30 , Issue.SUPPL. 1
    • Hente, R.1    Cordey, J.2    Rahn, B.A.3    Maghsudi, M.4    von Gumppenberg, S.5    Perren, S.M.6
  • 85
    • 50949109494 scopus 로고    scopus 로고
    • Pressure, oxygen tension and temperature in the periosteal callus during bone healing - an in vivo study in sheep
    • Epari D.R., Lienau J., Schell H., Witt F., and Duda G.N. Pressure, oxygen tension and temperature in the periosteal callus during bone healing - an in vivo study in sheep. Bone 43 4 (2008) 734-739
    • (2008) Bone , vol.43 , Issue.4 , pp. 734-739
    • Epari, D.R.1    Lienau, J.2    Schell, H.3    Witt, F.4    Duda, G.N.5
  • 86
    • 46449132756 scopus 로고    scopus 로고
    • Temporary distraction and compression of a diaphyseal osteotomy accelerates bone healing
    • Claes L., Augat P., Schorlemmer S., Konrads C., Ignatius A., and Ehrnthaller C. Temporary distraction and compression of a diaphyseal osteotomy accelerates bone healing. J Orthop Res 26 6 (2008) 772-777
    • (2008) J Orthop Res , vol.26 , Issue.6 , pp. 772-777
    • Claes, L.1    Augat, P.2    Schorlemmer, S.3    Konrads, C.4    Ignatius, A.5    Ehrnthaller, C.6
  • 87
    • 43049111785 scopus 로고    scopus 로고
    • Computer-guided CO2-laser osteotomy of the sheep tibia: technical prerequisites and first results
    • Kuttenberger J.J., Stubinger S., Waibel A., Werner M., Klasing M., Ivanenko M., et al. Computer-guided CO2-laser osteotomy of the sheep tibia: technical prerequisites and first results. Photomed Laser Surg 26 2 (2008) 129-136
    • (2008) Photomed Laser Surg , vol.26 , Issue.2 , pp. 129-136
    • Kuttenberger, J.J.1    Stubinger, S.2    Waibel, A.3    Werner, M.4    Klasing, M.5    Ivanenko, M.6
  • 88
    • 0030852363 scopus 로고    scopus 로고
    • The use of a coral composite implant containing bone morphogenetic protein to repair a segmental tibial defect in sheep
    • Gao T.J., Lindholm T.S., Kommonen B., Ragni P., Paronzini A., Lindholm T.C., et al. The use of a coral composite implant containing bone morphogenetic protein to repair a segmental tibial defect in sheep. Int Orthop 21 3 (1997) 194-200
    • (1997) Int Orthop , vol.21 , Issue.3 , pp. 194-200
    • Gao, T.J.1    Lindholm, T.S.2    Kommonen, B.3    Ragni, P.4    Paronzini, A.5    Lindholm, T.C.6
  • 89
    • 0033934158 scopus 로고    scopus 로고
    • Healing of autologous cancellous bone transplants and hydroxylapatite ceramics in tibial segment defects. Value of ultrasonic follow up
    • Wefer J., Wefer A., Schratt H.E., Thermann H., and Wippermann B.W. Healing of autologous cancellous bone transplants and hydroxylapatite ceramics in tibial segment defects. Value of ultrasonic follow up. Unfallchirurg 103 6 (2000) 452-461
    • (2000) Unfallchirurg , vol.103 , Issue.6 , pp. 452-461
    • Wefer, J.1    Wefer, A.2    Schratt, H.E.3    Thermann, H.4    Wippermann, B.W.5
  • 91
    • 12444321550 scopus 로고    scopus 로고
    • Localized insulin-like growth factor I delivery to enhance new bone formation
    • Meinel L., Zoidis E., Zapf J., Hassa P., Hottiger M.O., Auer J.A., et al. Localized insulin-like growth factor I delivery to enhance new bone formation. Bone 33 4 (2003) 660-672
    • (2003) Bone , vol.33 , Issue.4 , pp. 660-672
    • Meinel, L.1    Zoidis, E.2    Zapf, J.3    Hassa, P.4    Hottiger, M.O.5    Auer, J.A.6
  • 92
    • 33745778926 scopus 로고    scopus 로고
    • Reconstruction of extensive long bone defects in sheep using resorbable bioceramics based on silicon stabilized tricalcium phosphate
    • Mastrogiacomo M., Corsi A., Francioso E., Di Comite M., Monetti F., Scaglione S., et al. Reconstruction of extensive long bone defects in sheep using resorbable bioceramics based on silicon stabilized tricalcium phosphate. Tissue Eng 12 5 (2006) 1261-1273
    • (2006) Tissue Eng , vol.12 , Issue.5 , pp. 1261-1273
    • Mastrogiacomo, M.1    Corsi, A.2    Francioso, E.3    Di Comite, M.4    Monetti, F.5    Scaglione, S.6
  • 93
    • 33747024962 scopus 로고    scopus 로고
    • Mechanical and radiological assessment of the influence of rhTGFbeta-3 on bone regeneration in a segmental defect in the ovine tibia: pilot study
    • Maissen O., Eckhardt C., Gogolewski S., Glatt M., Arvinte T., Steiner A., et al. Mechanical and radiological assessment of the influence of rhTGFbeta-3 on bone regeneration in a segmental defect in the ovine tibia: pilot study. J Orthop Res 24 8 (2006) 1670-1678
    • (2006) J Orthop Res , vol.24 , Issue.8 , pp. 1670-1678
    • Maissen, O.1    Eckhardt, C.2    Gogolewski, S.3    Glatt, M.4    Arvinte, T.5    Steiner, A.6
  • 94
    • 28744457098 scopus 로고    scopus 로고
    • Bone formation in a long bone defect model using a platelet-rich plasma-loaded collagen scaffold
    • Sarkar M.R., Augat P., Shefelbine S.J., Schorlemmer S., Huber-Lang M., Claes L., et al. Bone formation in a long bone defect model using a platelet-rich plasma-loaded collagen scaffold. Biomaterials 27 9 (2006) 1817-1823
    • (2006) Biomaterials , vol.27 , Issue.9 , pp. 1817-1823
    • Sarkar, M.R.1    Augat, P.2    Shefelbine, S.J.3    Schorlemmer, S.4    Huber-Lang, M.5    Claes, L.6
  • 95
    • 34248175161 scopus 로고    scopus 로고
    • Biomechanical comparison of callus over a locked intramedullary nail in various segmental bone defects in a sheep model
    • Tyllianakis M., Deligianni D., Panagopoulos A., Pappas M., Sourgiadaki E., Mavrilas D., et al. Biomechanical comparison of callus over a locked intramedullary nail in various segmental bone defects in a sheep model. Med Sci Monit 13 5 (2007) BR125-BR130
    • (2007) Med Sci Monit , vol.13 , Issue.5
    • Tyllianakis, M.1    Deligianni, D.2    Panagopoulos, A.3    Pappas, M.4    Sourgiadaki, E.5    Mavrilas, D.6
  • 96
    • 36749090015 scopus 로고    scopus 로고
    • Tibial segmental bone defect treated with bone plate and cage filled with either xenogeneic composite or autologous cortical bone graft. An experimental study in sheep
    • Teixeira C.R., Rahal S.C., Volpi R.S., Taga R., Cestari T.M., Granjeiro J.M., et al. Tibial segmental bone defect treated with bone plate and cage filled with either xenogeneic composite or autologous cortical bone graft. An experimental study in sheep. Vet Comp Orthop Traumatol 20 4 (2007) 269-276
    • (2007) Vet Comp Orthop Traumatol , vol.20 , Issue.4 , pp. 269-276
    • Teixeira, C.R.1    Rahal, S.C.2    Volpi, R.S.3    Taga, R.4    Cestari, T.M.5    Granjeiro, J.M.6
  • 97
    • 58149247921 scopus 로고    scopus 로고
    • In vivo effects of modification of hydroxyapatite/collagen composites with and without chondroitin sulphate on bone remodeling in the sheep tibia
    • Schneiders W., Reinstorf A., Biewener A., Serra A., Grass R., Kinscher M., et al. In vivo effects of modification of hydroxyapatite/collagen composites with and without chondroitin sulphate on bone remodeling in the sheep tibia. J Orthop Res 27 1 (2009) 15-21
    • (2009) J Orthop Res , vol.27 , Issue.1 , pp. 15-21
    • Schneiders, W.1    Reinstorf, A.2    Biewener, A.3    Serra, A.4    Grass, R.5    Kinscher, M.6
  • 98
    • 0344958801 scopus 로고    scopus 로고
    • Fixation of femoral shaft osteotomy with an intramedullary composite rod: an experimental study on dogs with a two-year follow-up
    • Kettunen J., Makela A., Miettinen H., Nevalainen T., Heikkila M., Tormala P., et al. Fixation of femoral shaft osteotomy with an intramedullary composite rod: an experimental study on dogs with a two-year follow-up. J Biomater Sci Polym Ed 10 1 (1999) 33-45
    • (1999) J Biomater Sci Polym Ed , vol.10 , Issue.1 , pp. 33-45
    • Kettunen, J.1    Makela, A.2    Miettinen, H.3    Nevalainen, T.4    Heikkila, M.5    Tormala, P.6
  • 99
    • 15244341829 scopus 로고    scopus 로고
    • The effects of implant composition on extensor tenosynovitis in a canine distal radius fracture model
    • Sinicropi S.M., Su B.W., Raia F.J., Parisien M., Strauch R.J., and Rosenwasser M.P. The effects of implant composition on extensor tenosynovitis in a canine distal radius fracture model. J Hand Surg [Am] 30 2 (2005) 300-307
    • (2005) J Hand Surg [Am] , vol.30 , Issue.2 , pp. 300-307
    • Sinicropi, S.M.1    Su, B.W.2    Raia, F.J.3    Parisien, M.4    Strauch, R.J.5    Rosenwasser, M.P.6
  • 101
    • 0027179770 scopus 로고
    • Bone-healing patterns affected by loading, fracture fragment stability, fracture type, and fracture site compression
    • Aro H.T., and Chao E.Y. Bone-healing patterns affected by loading, fracture fragment stability, fracture type, and fracture site compression. Clin Orthop Relat Res 293 (1993) 8-17
    • (1993) Clin Orthop Relat Res , vol.293 , pp. 8-17
    • Aro, H.T.1    Chao, E.Y.2
  • 103
    • 0032103663 scopus 로고    scopus 로고
    • The effects of external mechanical stimulation on the healing of diaphyseal osteotomies fixed by flexible external fixation
    • Wolf S., Janousek A., Pfeil J., Veith W., Haas F., Duda G., et al. The effects of external mechanical stimulation on the healing of diaphyseal osteotomies fixed by flexible external fixation. Clin Biomech (Bristol, Avon) 13 4-5 (1998) 359-364
    • (1998) Clin Biomech (Bristol, Avon) , vol.13 , Issue.4-5 , pp. 359-364
    • Wolf, S.1    Janousek, A.2    Pfeil, J.3    Veith, W.4    Haas, F.5    Duda, G.6
  • 104
    • 53149124753 scopus 로고    scopus 로고
    • Mechanical induction of critically delayed bone healing in sheep: radiological and biomechanical results
    • Schell H., Thompson M.S., Bail H.J., Hoffmann J.E., Schill A., Duda G.N., et al. Mechanical induction of critically delayed bone healing in sheep: radiological and biomechanical results. J Biomech 41 14 (2008) 3066-3072
    • (2008) J Biomech , vol.41 , Issue.14 , pp. 3066-3072
    • Schell, H.1    Thompson, M.S.2    Bail, H.J.3    Hoffmann, J.E.4    Schill, A.5    Duda, G.N.6
  • 105
    • 0028968994 scopus 로고
    • Contaminated fractures of the tibia: a comparison of treatment modalities in an animal model
    • Curtis M.J., Brown P.R., Dick J.D., and Jinnah R.H. Contaminated fractures of the tibia: a comparison of treatment modalities in an animal model. J Orthop Res 13 2 (1995) 286-295
    • (1995) J Orthop Res , vol.13 , Issue.2 , pp. 286-295
    • Curtis, M.J.1    Brown, P.R.2    Dick, J.D.3    Jinnah, R.H.4
  • 106
    • 0036309478 scopus 로고    scopus 로고
    • Effect of recombinant human osteogenic protein-1 on the healing of a freshly closed diaphyseal fracture
    • den Boer F.C., Bramer J.A., Blokhuis T.J., Van Soest E.J., Jenner J.M., Patka P., et al. Effect of recombinant human osteogenic protein-1 on the healing of a freshly closed diaphyseal fracture. Bone 31 1 (2002) 158-164
    • (2002) Bone , vol.31 , Issue.1 , pp. 158-164
    • den Boer, F.C.1    Bramer, J.A.2    Blokhuis, T.J.3    Van Soest, E.J.4    Jenner, J.M.5    Patka, P.6
  • 107
    • 34748908793 scopus 로고    scopus 로고
    • A pelvic fracture model for the assessment of treatment options in a laboratory environment
    • Krappinger D., Schubert H., Wenzel V., Rieger M., Stadlbauer K.H., Blauth M., et al. A pelvic fracture model for the assessment of treatment options in a laboratory environment. Injury 38 10 (2007) 1151-1157
    • (2007) Injury , vol.38 , Issue.10 , pp. 1151-1157
    • Krappinger, D.1    Schubert, H.2    Wenzel, V.3    Rieger, M.4    Stadlbauer, K.H.5    Blauth, M.6
  • 108
    • 44449165971 scopus 로고    scopus 로고
    • Detection of simulated inflicted metaphyseal fractures in a fetal pig model: image optimization and dose reduction with computed radiography
    • Kleinman P.L., Zurakowski D., Strauss K.J., Cleveland R.H., Perez-Rosello J.M., Nichols D.P., et al. Detection of simulated inflicted metaphyseal fractures in a fetal pig model: image optimization and dose reduction with computed radiography. Radiology 247 2 (2008) 381-390
    • (2008) Radiology , vol.247 , Issue.2 , pp. 381-390
    • Kleinman, P.L.1    Zurakowski, D.2    Strauss, K.J.3    Cleveland, R.H.4    Perez-Rosello, J.M.5    Nichols, D.P.6
  • 109
    • 0035734486 scopus 로고    scopus 로고
    • The prevention of experimental osteomyelitis in a model of gunshot fracture in the pig
    • Hill P.F., and Watkins P.E. The prevention of experimental osteomyelitis in a model of gunshot fracture in the pig. Eur J Orthop Surg Traumatol 11 (2001) 237-241
    • (2001) Eur J Orthop Surg Traumatol , vol.11 , pp. 237-241
    • Hill, P.F.1    Watkins, P.E.2
  • 110
    • 1842841938 scopus 로고    scopus 로고
    • Systemic application of growth hormone for enhancement of secondary and intramembranous fracture healing
    • Bail H.J., Kolbeck S., Krummrey G., Schmidmaier G., Haas N.P., and Raschke M.J. Systemic application of growth hormone for enhancement of secondary and intramembranous fracture healing. Horm Res 58 Suppl. 3 (2002) 39-42
    • (2002) Horm Res , vol.58 , Issue.SUPPL. 3 , pp. 39-42
    • Bail, H.J.1    Kolbeck, S.2    Krummrey, G.3    Schmidmaier, G.4    Haas, N.P.5    Raschke, M.J.6
  • 111
    • 0025057930 scopus 로고
    • Vertebral end-plate failure in porcine and bovine models of spinal fracture instrumentation
    • Allan D.G., Russell G.G., Moreau M.J., Raso V.J., and Budney D. Vertebral end-plate failure in porcine and bovine models of spinal fracture instrumentation. J Orthop Res 8 1 (1990) 154-156
    • (1990) J Orthop Res , vol.8 , Issue.1 , pp. 154-156
    • Allan, D.G.1    Russell, G.G.2    Moreau, M.J.3    Raso, V.J.4    Budney, D.5
  • 112
    • 0026451105 scopus 로고
    • A reproducible porcine vertebral fracture for biomechanical testing of spinal fixation devices
    • Russell G., Lavoie G., Evenson R., Moreau M., Budney D., and Raso V.J. A reproducible porcine vertebral fracture for biomechanical testing of spinal fixation devices. Clin Orthop Relat Res 284 (1992) 267-272
    • (1992) Clin Orthop Relat Res , vol.284 , pp. 267-272
    • Russell, G.1    Lavoie, G.2    Evenson, R.3    Moreau, M.4    Budney, D.5    Raso, V.J.6
  • 113
    • 0242569459 scopus 로고    scopus 로고
    • The fracture gap size influences the local vascularization and tissue differentiation in callus healing
    • Claes L., Eckert-Hubner K., and Augat P. The fracture gap size influences the local vascularization and tissue differentiation in callus healing. Langenbecks Arch Surg 388 5 (2003) 316-322
    • (2003) Langenbecks Arch Surg , vol.388 , Issue.5 , pp. 316-322
    • Claes, L.1    Eckert-Hubner, K.2    Augat, P.3
  • 115
    • 56749158092 scopus 로고    scopus 로고
    • A new animal model for bone atrophic nonunion: fixation by external fixator
    • Kaspar K., Matziolis G., Strube P., Senturk U., Dormann S., Bail H.J., et al. A new animal model for bone atrophic nonunion: fixation by external fixator. J Orthop Res 26 12 (2008) 1649-1655
    • (2008) J Orthop Res , vol.26 , Issue.12 , pp. 1649-1655
    • Kaspar, K.1    Matziolis, G.2    Strube, P.3    Senturk, U.4    Dormann, S.5    Bail, H.J.6
  • 116
    • 0022469996 scopus 로고
    • Quantitative comparisons of healing in cranial fresh autografts, frozen autografts and processed autografts, and allografts in canine skull defects
    • Oklund S.A., Prolo D.J., Gutierrez R.V., and King S.E. Quantitative comparisons of healing in cranial fresh autografts, frozen autografts and processed autografts, and allografts in canine skull defects. Clin Orthop Relat Res 205 (1986) 269-291
    • (1986) Clin Orthop Relat Res , vol.205 , pp. 269-291
    • Oklund, S.A.1    Prolo, D.J.2    Gutierrez, R.V.3    King, S.E.4
  • 117
    • 42049106205 scopus 로고    scopus 로고
    • Bone generation in the reconstruction of a critical size calvarial defect in an experimental model
    • Por Y.C., Barcelo C.R., Salyer K.E., Genecov D.G., Troxel K., Gendler E., et al. Bone generation in the reconstruction of a critical size calvarial defect in an experimental model. J Craniofac Surg 19 2 (2008) 383-392
    • (2008) J Craniofac Surg , vol.19 , Issue.2 , pp. 383-392
    • Por, Y.C.1    Barcelo, C.R.2    Salyer, K.E.3    Genecov, D.G.4    Troxel, K.5    Gendler, E.6
  • 118
    • 35349020566 scopus 로고    scopus 로고
    • Repair of cranial bone defects with adipose derived stem cells and coral scaffold in a canine model
    • Cui L., Liu B., Liu G., Zhang W., Cen L., Sun J., et al. Repair of cranial bone defects with adipose derived stem cells and coral scaffold in a canine model. Biomaterials 28 36 (2007) 5477-5486
    • (2007) Biomaterials , vol.28 , Issue.36 , pp. 5477-5486
    • Cui, L.1    Liu, B.2    Liu, G.3    Zhang, W.4    Cen, L.5    Sun, J.6
  • 120
    • 35348915916 scopus 로고    scopus 로고
    • Polycaprolactone-20% tricalcium phosphate scaffolds in combination with platelet-rich plasma for the treatment of critical-sized defects of the mandible: a pilot study
    • Rai B., Ho K.H., Lei Y., Si-Hoe K.M., Jeremy Teo C.M., Yacob K.B., et al. Polycaprolactone-20% tricalcium phosphate scaffolds in combination with platelet-rich plasma for the treatment of critical-sized defects of the mandible: a pilot study. J Oral Maxillofac Surg 65 11 (2007) 2195-2205
    • (2007) J Oral Maxillofac Surg , vol.65 , Issue.11 , pp. 2195-2205
    • Rai, B.1    Ho, K.H.2    Lei, Y.3    Si-Hoe, K.M.4    Jeremy Teo, C.M.5    Yacob, K.B.6
  • 121
    • 34547674634 scopus 로고    scopus 로고
    • Experimental study on reconstruction of segmental mandible defects using tissue engineered bone combined bone marrow stromal cells with three-dimensional tricalcium phosphate
    • He Y., Zhang Z.Y., Zhu H.G., Qiu W., Jiang X., and Guo W. Experimental study on reconstruction of segmental mandible defects using tissue engineered bone combined bone marrow stromal cells with three-dimensional tricalcium phosphate. J Craniofac Surg 18 4 (2007) 800-805
    • (2007) J Craniofac Surg , vol.18 , Issue.4 , pp. 800-805
    • He, Y.1    Zhang, Z.Y.2    Zhu, H.G.3    Qiu, W.4    Jiang, X.5    Guo, W.6
  • 122
    • 0346123084 scopus 로고    scopus 로고
    • Development of a porous poly(L-lactic acid)/hydroxyapatite/collagen scaffold as a BMP delivery system and its use in healing canine segmental bone defect
    • Hu Y., Zhang C., Zhang S., Xiong Z., and Xu J. Development of a porous poly(L-lactic acid)/hydroxyapatite/collagen scaffold as a BMP delivery system and its use in healing canine segmental bone defect. J Biomed Mater Res A 67 2 (2003) 591-598
    • (2003) J Biomed Mater Res A , vol.67 , Issue.2 , pp. 591-598
    • Hu, Y.1    Zhang, C.2    Zhang, S.3    Xiong, Z.4    Xu, J.5
  • 124
    • 34948872003 scopus 로고    scopus 로고
    • Bone formation following OP-1 implantation is improved by addition of autogenous bone marrow cells in a canine femur defect model
    • Takigami H., Kumagai K., Latson L., Togawa D., Bauer T., Powell K., et al. Bone formation following OP-1 implantation is improved by addition of autogenous bone marrow cells in a canine femur defect model. J Orthop Res 25 10 (2007) 1333-1342
    • (2007) J Orthop Res , vol.25 , Issue.10 , pp. 1333-1342
    • Takigami, H.1    Kumagai, K.2    Latson, L.3    Togawa, D.4    Bauer, T.5    Powell, K.6
  • 125
    • 33744460788 scopus 로고    scopus 로고
    • Bone grafts prepared with selective cell retention technology heal canine segmental defects as effectively as autograft
    • Brodke D., Pedrozo H.A., Kapur T.A., Attawia M., Kraus K.H., Holy C.E., et al. Bone grafts prepared with selective cell retention technology heal canine segmental defects as effectively as autograft. J Orthop Res 24 5 (2006) 857-866
    • (2006) J Orthop Res , vol.24 , Issue.5 , pp. 857-866
    • Brodke, D.1    Pedrozo, H.A.2    Kapur, T.A.3    Attawia, M.4    Kraus, K.H.5    Holy, C.E.6
  • 126
    • 0025609757 scopus 로고
    • Cyclosporin A and tissue antigen matching in bone transplantation. Fibular allografts studied in the dog
    • Welter J.F., Shaffer J.W., Stevenson S., Davy D.T., Field G.A., Klein L., et al. Cyclosporin A and tissue antigen matching in bone transplantation. Fibular allografts studied in the dog. Acta Orthop Scand 61 6 (1990) 517-527
    • (1990) Acta Orthop Scand , vol.61 , Issue.6 , pp. 517-527
    • Welter, J.F.1    Shaffer, J.W.2    Stevenson, S.3    Davy, D.T.4    Field, G.A.5    Klein, L.6
  • 127
    • 43149126093 scopus 로고    scopus 로고
    • Biomechanical and histologic evaluation of the Norian craniofacial repair system and Norian Craniofacial Repair System Fast Set Putty in the long-term reconstruction of full-thickness skull defects in a sheep model
    • Zins J.E., Moreira-Gonzalez A., Parikh A., Arslan E., Bauer T., and Siemionow M. Biomechanical and histologic evaluation of the Norian craniofacial repair system and Norian Craniofacial Repair System Fast Set Putty in the long-term reconstruction of full-thickness skull defects in a sheep model. Plast Reconstr Surg 121 5 (2008) 271e-282e
    • (2008) Plast Reconstr Surg , vol.121 , Issue.5
    • Zins, J.E.1    Moreira-Gonzalez, A.2    Parikh, A.3    Arslan, E.4    Bauer, T.5    Siemionow, M.6
  • 128
    • 33645885312 scopus 로고    scopus 로고
    • Contour and volume assessment of repairing mandibular osteoperiosteal continuity defects in sheep using recombinant human osteogenic protein 1
    • Abu-Serriah M., Ayoub A., Wray D., Milne N., Carmichael S., and Boyd J. Contour and volume assessment of repairing mandibular osteoperiosteal continuity defects in sheep using recombinant human osteogenic protein 1. J Craniomaxillofac Surg 34 3 (2006) 162-167
    • (2006) J Craniomaxillofac Surg , vol.34 , Issue.3 , pp. 162-167
    • Abu-Serriah, M.1    Ayoub, A.2    Wray, D.3    Milne, N.4    Carmichael, S.5    Boyd, J.6
  • 129
    • 33644531237 scopus 로고    scopus 로고
    • The copolymer of epsilon-caprolactone-lactide and tricalcium phosphate does not enhance bone growth in mandibular defect of sheep
    • Ekholm M., Hietanen J., Tulamo R.M., Muhonen J., Lindqvist C., Kellomaki M., et al. The copolymer of epsilon-caprolactone-lactide and tricalcium phosphate does not enhance bone growth in mandibular defect of sheep. J Mater Sci Mater Med 17 2 (2006) 139-145
    • (2006) J Mater Sci Mater Med , vol.17 , Issue.2 , pp. 139-145
    • Ekholm, M.1    Hietanen, J.2    Tulamo, R.M.3    Muhonen, J.4    Lindqvist, C.5    Kellomaki, M.6
  • 130
    • 40949142386 scopus 로고    scopus 로고
    • Matrix-induced autologous chondrocyte implantation in sheep: objective assessments including confocal arthroscopy
    • Jones C.W., Willers C., Keogh A., Smolinski D., Fick D., Yates P.J., et al. Matrix-induced autologous chondrocyte implantation in sheep: objective assessments including confocal arthroscopy. J Orthop Res 26 3 (2008) 292-303
    • (2008) J Orthop Res , vol.26 , Issue.3 , pp. 292-303
    • Jones, C.W.1    Willers, C.2    Keogh, A.3    Smolinski, D.4    Fick, D.5    Yates, P.J.6
  • 131
    • 34547681854 scopus 로고    scopus 로고
    • A tissue engineering approach to bone repair in large animal models and in clinical practice
    • Cancedda R., Giannoni P., and Mastrogiacomo M. A tissue engineering approach to bone repair in large animal models and in clinical practice. Biomaterials 28 29 (2007) 4240-4250
    • (2007) Biomaterials , vol.28 , Issue.29 , pp. 4240-4250
    • Cancedda, R.1    Giannoni, P.2    Mastrogiacomo, M.3
  • 132
    • 33749142958 scopus 로고    scopus 로고
    • An animal model in sheep for biocompatibility testing of biomaterials in cancellous bones
    • Nuss K.M., Auer J.A., Boos A., and von Rechenberg B. An animal model in sheep for biocompatibility testing of biomaterials in cancellous bones. BMC Musculoskelet Disord 7 (2006) 67
    • (2006) BMC Musculoskelet Disord , vol.7 , pp. 67
    • Nuss, K.M.1    Auer, J.A.2    Boos, A.3    von Rechenberg, B.4
  • 134
    • 33747840376 scopus 로고    scopus 로고
    • Induction of a barrier membrane to facilitate reconstruction of massive segmental diaphyseal bone defects: an ovine model
    • Viateau V., Guillemin G., Calando Y., Logeart D., Oudina K., Sedel L., et al. Induction of a barrier membrane to facilitate reconstruction of massive segmental diaphyseal bone defects: an ovine model. Vet Surg 35 5 (2006) 445-452
    • (2006) Vet Surg , vol.35 , Issue.5 , pp. 445-452
    • Viateau, V.1    Guillemin, G.2    Calando, Y.3    Logeart, D.4    Oudina, K.5    Sedel, L.6
  • 135
    • 51649108090 scopus 로고    scopus 로고
    • OP-1 application in bone allograft integration: preliminary results in sheep experimental surgery
    • Donati D., Di Bella C., Lucarelli E., Dozza B., Frisoni T., Aldini N.N., et al. OP-1 application in bone allograft integration: preliminary results in sheep experimental surgery. Injury 39 Suppl. 2 (2008) S65-S72
    • (2008) Injury , vol.39 , Issue.SUPPL. 2
    • Donati, D.1    Di Bella, C.2    Lucarelli, E.3    Dozza, B.4    Frisoni, T.5    Aldini, N.N.6
  • 136
    • 11844304901 scopus 로고    scopus 로고
    • Low-intensity ultrasound enhances maturation of callus after segmental transport
    • Claes L., Ruter A., and Mayr E. Low-intensity ultrasound enhances maturation of callus after segmental transport. Clin Orthop Relat Res 430 (2005) 189-194
    • (2005) Clin Orthop Relat Res , vol.430 , pp. 189-194
    • Claes, L.1    Ruter, A.2    Mayr, E.3
  • 137
    • 54549092429 scopus 로고    scopus 로고
    • Bone regeneration of critical calvarial defect in goat model by PLGA/TCP/rhBMP-2 scaffolds prepared by low-temperature rapid-prototyping technology
    • Yu D., Li Q., Mu X., Chang T., and Xiong Z. Bone regeneration of critical calvarial defect in goat model by PLGA/TCP/rhBMP-2 scaffolds prepared by low-temperature rapid-prototyping technology. Int J Oral Maxillofac Surg 37 10 (2008) 929-934
    • (2008) Int J Oral Maxillofac Surg , vol.37 , Issue.10 , pp. 929-934
    • Yu, D.1    Li, Q.2    Mu, X.3    Chang, T.4    Xiong, Z.5
  • 138
    • 24944439046 scopus 로고    scopus 로고
    • Reconstruction of the mandible with a poly(D,L-lactide) scaffold, autogenous corticocancellous bone graft, and autogenous platelet-rich plasma: an animal experiment
    • Fennis J.P., Stoelinga P.J., Merkx M.A., and Jansen J.A. Reconstruction of the mandible with a poly(D,L-lactide) scaffold, autogenous corticocancellous bone graft, and autogenous platelet-rich plasma: an animal experiment. Tissue Eng 11 7-8 (2005) 1045-1053
    • (2005) Tissue Eng , vol.11 , Issue.7-8 , pp. 1045-1053
    • Fennis, J.P.1    Stoelinga, P.J.2    Merkx, M.A.3    Jansen, J.A.4
  • 139
    • 1842864939 scopus 로고    scopus 로고
    • Bone tissue engineering in a critical size defect compared to ectopic implantations in the goat
    • Kruyt M.C., Dhert W.J., Yuan H., Wilson C.E., van Blitterswijk C.A., Verbout A.J., et al. Bone tissue engineering in a critical size defect compared to ectopic implantations in the goat. J Orthop Res 22 3 (2004) 544-551
    • (2004) J Orthop Res , vol.22 , Issue.3 , pp. 544-551
    • Kruyt, M.C.1    Dhert, W.J.2    Yuan, H.3    Wilson, C.E.4    van Blitterswijk, C.A.5    Verbout, A.J.6
  • 140
    • 0030111077 scopus 로고    scopus 로고
    • Application of porous PEO/PBT copolymers for bone replacement
    • Radder A.M., Leenders H., and van Blitterswijk C.A. Application of porous PEO/PBT copolymers for bone replacement. J Biomed Mater Res 30 3 (1996) 341-351
    • (1996) J Biomed Mater Res , vol.30 , Issue.3 , pp. 341-351
    • Radder, A.M.1    Leenders, H.2    van Blitterswijk, C.A.3
  • 141
    • 33646351965 scopus 로고    scopus 로고
    • Tissue-engineered bone repair of goat-femur defects with osteogenically induced bone marrow stromal cells
    • Zhu L., Liu W., Cui L., and Cao Y. Tissue-engineered bone repair of goat-femur defects with osteogenically induced bone marrow stromal cells. Tissue Eng 12 3 (2006) 423-433
    • (2006) Tissue Eng , vol.12 , Issue.3 , pp. 423-433
    • Zhu, L.1    Liu, W.2    Cui, L.3    Cao, Y.4
  • 142
    • 34249949388 scopus 로고    scopus 로고
    • Impacted bone and calcium phosphate cement for repair of femoral head defects: a pilot study
    • Rijnen W.H., Gardeniers J.W., Schreurs B.W., and Buma P. Impacted bone and calcium phosphate cement for repair of femoral head defects: a pilot study. Clin Orthop Relat Res 459 (2007) 216-221
    • (2007) Clin Orthop Relat Res , vol.459 , pp. 216-221
    • Rijnen, W.H.1    Gardeniers, J.W.2    Schreurs, B.W.3    Buma, P.4
  • 143
    • 27644441812 scopus 로고    scopus 로고
    • Immune response and effect of adenovirus-mediated human BMP-2 gene transfer on the repair of segmental tibial bone defects in goats
    • Xu X.L., Tang T., Dai K., Zhu Z., Guo X.E., Yu C., et al. Immune response and effect of adenovirus-mediated human BMP-2 gene transfer on the repair of segmental tibial bone defects in goats. Acta Orthop 76 5 (2005) 637-646
    • (2005) Acta Orthop , vol.76 , Issue.5 , pp. 637-646
    • Xu, X.L.1    Tang, T.2    Dai, K.3    Zhu, Z.4    Guo, X.E.5    Yu, C.6
  • 144
    • 57749116117 scopus 로고    scopus 로고
    • The repair of segmental bone defects with porous bioglass: An experimental study in goat
    • Nandi SK, Kundu B, Datta S, De DK, Basu D. The repair of segmental bone defects with porous bioglass: an experimental study in goat. Res Vet Sci 2009;86(1):162-73.
    • (2009) Res Vet Sci , vol.86 , Issue.1 , pp. 162-173
    • Nandi, S.K.1    Kundu, B.2    Datta, S.3    De, D.K.4    Basu, D.5
  • 145
    • 47249092778 scopus 로고    scopus 로고
    • Healing of critical-size cranial defects in guinea pigs using a bovine bone-derived resorbable membrane
    • Taga M.L., Granjeiro J.M., Cestari T.M., and Taga R. Healing of critical-size cranial defects in guinea pigs using a bovine bone-derived resorbable membrane. Int J Oral Maxillofac Implants 23 3 (2008) 427-436
    • (2008) Int J Oral Maxillofac Implants , vol.23 , Issue.3 , pp. 427-436
    • Taga, M.L.1    Granjeiro, J.M.2    Cestari, T.M.3    Taga, R.4
  • 146
    • 50349102268 scopus 로고    scopus 로고
    • Porous collagen-apatite nanocomposite foams as bone regeneration scaffolds
    • Pek Y.S., Gao S., Arshad M.S., Leck K.J., and Ying J.Y. Porous collagen-apatite nanocomposite foams as bone regeneration scaffolds. Biomaterials 29 32 (2008) 4300-4305
    • (2008) Biomaterials , vol.29 , Issue.32 , pp. 4300-4305
    • Pek, Y.S.1    Gao, S.2    Arshad, M.S.3    Leck, K.J.4    Ying, J.Y.5
  • 147
    • 0034810203 scopus 로고    scopus 로고
    • Homologous growth hormone accelerates healing of segmental bone defects
    • Raschke M., Kolbeck S., Bail H., Schmidmaier G., Flyvbjerg A., Lindner T., et al. Homologous growth hormone accelerates healing of segmental bone defects. Bone 29 4 (2001) 368-373
    • (2001) Bone , vol.29 , Issue.4 , pp. 368-373
    • Raschke, M.1    Kolbeck, S.2    Bail, H.3    Schmidmaier, G.4    Flyvbjerg, A.5    Lindner, T.6
  • 148
    • 1342322628 scopus 로고    scopus 로고
    • Interface of unloaded titanium implants in the iliac crest, fibula, and scapula: a histomorphometric and biomechanical study in the pig
    • Rohner D., Tay A., Chung S.M., and Hutmacher D.W. Interface of unloaded titanium implants in the iliac crest, fibula, and scapula: a histomorphometric and biomechanical study in the pig. Int J Oral Maxillofac Implants 19 1 (2004) 52-58
    • (2004) Int J Oral Maxillofac Implants , vol.19 , Issue.1 , pp. 52-58
    • Rohner, D.1    Tay, A.2    Chung, S.M.3    Hutmacher, D.W.4
  • 149
    • 0031262977 scopus 로고    scopus 로고
    • Regeneration of diaphyseal bone defects using resorbable poly(L/DL-lactide) and poly(D-lactide) membranes in the Yucatan pig model
    • Meinig R.P., Buesing C.M., Helm J., and Gogolewski S. Regeneration of diaphyseal bone defects using resorbable poly(L/DL-lactide) and poly(D-lactide) membranes in the Yucatan pig model. J Orthop Trauma 11 8 (1997) 551-558
    • (1997) J Orthop Trauma , vol.11 , Issue.8 , pp. 551-558
    • Meinig, R.P.1    Buesing, C.M.2    Helm, J.3    Gogolewski, S.4
  • 150
    • 0036482664 scopus 로고    scopus 로고
    • A newly designed vertebral replacement implant to reconstruct the thoracolumbar spine anteriorly
    • Vanderschot P., Schepers E., Vanschoonwinkel A., and Broos P. A newly designed vertebral replacement implant to reconstruct the thoracolumbar spine anteriorly. Acta Chir Belg 102 1 (2002) 37-45
    • (2002) Acta Chir Belg , vol.102 , Issue.1 , pp. 37-45
    • Vanderschot, P.1    Schepers, E.2    Vanschoonwinkel, A.3    Broos, P.4
  • 151
    • 39149124477 scopus 로고    scopus 로고
    • State of the art and future directions of scaffold-based bone engineering from a biomaterials perspective
    • Hutmacher D.W., Schantz J.T., Lam C.X., Tan K.C., and Lim T.C. State of the art and future directions of scaffold-based bone engineering from a biomaterials perspective. J Tissue Eng Regen Med 1 4 (2007) 245-260
    • (2007) J Tissue Eng Regen Med , vol.1 , Issue.4 , pp. 245-260
    • Hutmacher, D.W.1    Schantz, J.T.2    Lam, C.X.3    Tan, K.C.4    Lim, T.C.5
  • 152
    • 33847147231 scopus 로고    scopus 로고
    • Differentiating human bone from animal bone: a review of histological methods
    • Hillier M.L., and Bell L.S. Differentiating human bone from animal bone: a review of histological methods. J Forensic Sci 52 2 (2007) 249-263
    • (2007) J Forensic Sci , vol.52 , Issue.2 , pp. 249-263
    • Hillier, M.L.1    Bell, L.S.2
  • 153
    • 0036562640 scopus 로고    scopus 로고
    • The sheep as a model for osteoporosis in humans
    • Turner A.S. The sheep as a model for osteoporosis in humans. Vet J 163 3 (2002) 232-239
    • (2002) Vet J , vol.163 , Issue.3 , pp. 232-239
    • Turner, A.S.1
  • 157
    • 0030719898 scopus 로고    scopus 로고
    • Changes in canine cortical and cancellous bone mechanical properties following immobilization and remobilization with exercise
    • Kaneps A.J., Stover S.M., and Lane N.E. Changes in canine cortical and cancellous bone mechanical properties following immobilization and remobilization with exercise. Bone 21 5 (1997) 419-423
    • (1997) Bone , vol.21 , Issue.5 , pp. 419-423
    • Kaneps, A.J.1    Stover, S.M.2    Lane, N.E.3
  • 159
    • 18044375988 scopus 로고    scopus 로고
    • Interrelationship of trabecular mechanical and microstructural properties in sheep trabecular bone
    • Mittra E., Rubin C., and Qin Y.X. Interrelationship of trabecular mechanical and microstructural properties in sheep trabecular bone. J Biomech 38 6 (2005) 1229-1237
    • (2005) J Biomech , vol.38 , Issue.6 , pp. 1229-1237
    • Mittra, E.1    Rubin, C.2    Qin, Y.X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.