Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site

Journal of Biological Chemistry

Volumn 286, Issue 39, 2011, Pages 34164-34174

  Li, Changhong ^a   Li, Ming ^b   Chen, Pan ^a   Narayan, Srinivas ^a   Matschinsky, Franz M ^c   Bennett, Michael J ^a   Stanley, Charles A ^a   Smith, Thomas J ^b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b DONALD DANFORTH PLANT SCIENCE CENTER   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD GLUCOSE LEVEL; EPICATECHIN; EPIGALLOCATECHIN GALLATE; GAIN-OF FUNCTION; GALLATE; GENETIC DISORDERS; GLUTAMATE DEHYDROGENASE; GREEN TEA; GREEN TEA POLYPHENOLS; HYPERAMMONEMIA; IN-VITRO; IN-VIVO; INSULIN SECRETION; L-GLUTAMATE; ORAL ADMINISTRATION; OXIDATIVE DEAMINATION; PANCREATIC ISLET; POLYPHENOLS; RAT ISLETS; SITE DIRECTED MUTAGENESIS; TRANSGENIC MICE; WILD TYPES;

AMINO ACIDS; ELECTROCARDIOGRAPHY; GLUCOSE; INSULIN; METABOLISM; PHENOLS;

MAMMALS;

ADENOSINE DIPHOSPHATE; EPICATECHIN GALLATE; EPIGALLOCATECHIN GALLATE; GLUCOSE; GLUTAMATE DEHYDROGENASE; GLUTAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GLUCOSE BLOOD LEVEL; HYPERAMMONEMIA; HYPERINSULINISM; HYPERINSULINISM HYPERAMMONEMIA SYNDROME; MOUSE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL;

ADENOSINE DIPHOSPHATE; ANIMALS; ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CATALYTIC DOMAIN; CATECHIN; GLUCOSE; GLUTAMATE DEHYDROGENASE; GLUTAMINE; HUMANS; ISLETS OF LANGERHANS; MICE; MICE, TRANSGENIC; MUTAGENESIS, SITE-DIRECTED; RATS; TEA;

ANIMALIA; MUS MUSCULUS; RATTUS;

EID: 80053193812     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.268599     Document Type: Article

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