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Volumn 6, Issue 3, 2015, Pages 1531-1543

Helicobacter pylori bacteria alter the p53 stress response via Erk-HDM2 pathway

Author keywords

CagA; Gastric tumor; HDM2; Helicobacter pylori; p53

Indexed keywords

CAGA PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN MDM2; PROTEIN P53; UVOMORULIN; MDM2 PROTEIN, HUMAN;

EID: 84922749459     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2828     Document Type: Article
Times cited : (32)

References (38)
  • 2
    • 70349211747 scopus 로고    scopus 로고
    • Coadaptation of Helicobacter pylori and humans: ancient history, modern implications
    • Atherton JC, Blaser MJ. Coadaptation of Helicobacter pylori and humans: ancient history, modern implications. J Clin Invest. 2009; 119:2475-2487.
    • (2009) J Clin Invest , vol.119 , pp. 2475-2487
    • Atherton, J.C.1    Blaser, M.J.2
  • 3
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas
    • Peek RM, Jr., Blaser MJ. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer. 2002; 2:28-37.
    • (2002) Nat Rev Cancer , vol.2 , pp. 28-37
    • Peek, R.M.1    Blaser, M.J.2
  • 8
    • 84870999066 scopus 로고    scopus 로고
    • Reactive oxygen species-induced autophagic degradation of Helicobacter pylori CagA is specifically suppressed in cancer stem-like cells
    • Tsugawa H, Suzuki H, Saya H, Hatakeyama M, Hirayama T, Hirata K, Nagano O, Matsuzaki J, Hibi T. Reactive oxygen species-induced autophagic degradation of Helicobacter pylori CagA is specifically suppressed in cancer stem-like cells. Cell Host Microbe. 2012; 12:764-777.
    • (2012) Cell Host Microbe , vol.12 , pp. 764-777
    • Tsugawa, H.1    Suzuki, H.2    Saya, H.3    Hatakeyama, M.4    Hirayama, T.5    Hirata, K.6    Nagano, O.7    Matsuzaki, J.8    Hibi, T.9
  • 9
    • 84866540647 scopus 로고    scopus 로고
    • Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses
    • Wei J, Noto J, Zaika E, Romero-Gallo J, Correa P, El-Rifai W, Peek RM, Zaika A. Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses. Proc Natl Acad Sci U S A. 2012; 109:E2543-2550.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. E2543-E2550
    • Wei, J.1    Noto, J.2    Zaika, E.3    Romero-Gallo, J.4    Correa, P.5    El-Rifai, W.6    Peek, R.M.7    Zaika, A.8
  • 10
    • 82355171817 scopus 로고    scopus 로고
    • "Targeted disruption of the epithelial-barrier by Helicobacter pylori"
    • Wroblewski LE, Peek RM, Jr. "Targeted disruption of the epithelial-barrier by Helicobacter pylori". Cell Commun Signal. 2011; 9:29.
    • (2011) Cell Commun Signal , vol.9 , pp. 29
    • Wroblewski, L.E.1    Peek, R.M.2
  • 12
    • 0031809678 scopus 로고    scopus 로고
    • H pylori infection is associated with downregulation of E-cadherin, a molecule involved in epithelial cell adhesion and proliferation control
    • Terres AM, Pajares JM, O'Toole D, Ahern S, Kelleher D. H pylori infection is associated with downregulation of E-cadherin, a molecule involved in epithelial cell adhesion and proliferation control. J Clin Pathol. 1998; 51:410-412.
    • (1998) J Clin Pathol , vol.51 , pp. 410-412
    • Terres, A.M.1    Pajares, J.M.2    O'Toole, D.3    Ahern, S.4    Kelleher, D.5
  • 13
    • 30644458570 scopus 로고    scopus 로고
    • Balancing cell adhesion and Wnt signaling, the key role of beta-catenin
    • Brembeck FH, Rosario M, Birchmeier W. Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. Curr Opin Genet Dev. 2006; 16:51-59.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 51-59
    • Brembeck, F.H.1    Rosario, M.2    Birchmeier, W.3
  • 14
    • 80855127793 scopus 로고    scopus 로고
    • Helicobacter pylori activates calpain via toll-like receptor 2 to disrupt adherens junctions in human gastric epithelial cells
    • O'Connor PM, Lapointe TK, Jackson S, Beck PL, Jones NL, Buret AG. Helicobacter pylori activates calpain via toll-like receptor 2 to disrupt adherens junctions in human gastric epithelial cells. Infect Immun. 2011; 79:3887-3894.
    • (2011) Infect Immun , vol.79 , pp. 3887-3894
    • O'Connor, P.M.1    Lapointe, T.K.2    Jackson, S.3    Beck, P.L.4    Jones, N.L.5    Buret, A.G.6
  • 18
    • 0037537477 scopus 로고    scopus 로고
    • Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer
    • Chan AO, Lam SK, Wong BC, Wong WM, Yuen MF, Yeung YH, Hui WM, Rashid A, Kwong YL. Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer. Gut. 2003; 52:502-506.
    • (2003) Gut , vol.52 , pp. 502-506
    • Chan, A.O.1    Lam, S.K.2    Wong, B.C.3    Wong, W.M.4    Yuen, M.F.5    Yeung, Y.H.6    Hui, W.M.7    Rashid, A.8    Kwong, Y.L.9
  • 20
    • 84857036920 scopus 로고    scopus 로고
    • Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffusetype gastric cancer
    • Shimada S, Mimata A, Sekine M, Mogushi K, Akiyama Y, Fukamachi H, Jonkers J, Tanaka H, Eishi Y, Yuasa Y. Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffusetype gastric cancer. Gut. 2012; 61:344-353.
    • (2012) Gut , vol.61 , pp. 344-353
    • Shimada, S.1    Mimata, A.2    Sekine, M.3    Mogushi, K.4    Akiyama, Y.5    Fukamachi, H.6    Jonkers, J.7    Tanaka, H.8    Eishi, Y.9    Yuasa, Y.10
  • 23
    • 65349195081 scopus 로고    scopus 로고
    • Establishment of conditionally immortalized epithelial cell lines from the intestinal tissue of adult normal and transgenic mice
    • Whitehead RH, Robinson PS. Establishment of conditionally immortalized epithelial cell lines from the intestinal tissue of adult normal and transgenic mice. Am J Physiol Gastrointest Liver Physiol. 2009; 296:G455-460.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296 , pp. G455-G460
    • Whitehead, R.H.1    Robinson, P.S.2
  • 24
    • 0034193343 scopus 로고    scopus 로고
    • A role for the p38 mitogen-acitvated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents
    • Sanchez-Prieto R, Rojas JM, Taya Y, Gutkind JS. A role for the p38 mitogen-acitvated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents. Cancer Res. 2000; 60:2464-2472.
    • (2000) Cancer Res , vol.60 , pp. 2464-2472
    • Sanchez-Prieto, R.1    Rojas, J.M.2    Taya, Y.3    Gutkind, J.S.4
  • 26
    • 0033485261 scopus 로고    scopus 로고
    • Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
    • Bulavin DV, Saito S, Hollander MC, Sakaguchi K, Anderson CW, Appella E, Fornace AJ, Jr. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO J. 1999; 18:6845-6854.
    • (1999) EMBO J , vol.18 , pp. 6845-6854
    • Bulavin, D.V.1    Saito, S.2    Hollander, M.C.3    Sakaguchi, K.4    Anderson, C.W.5    Appella, E.6    Fornace, A.J.7
  • 27
    • 0035736487 scopus 로고    scopus 로고
    • HER-2/neu induces p5 ubiquitination via Akt-mediated MDM2 phosphorylation
    • Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, Hung MC. HER-2/neu induces p5 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat Cell Biol. 2001; 3:973-982.
    • (2001) Nat Cell Biol , vol.3 , pp. 973-982
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Zou, Y.4    Spohn, B.5    Hung, M.C.6
  • 28
    • 4143053880 scopus 로고    scopus 로고
    • Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation
    • Feng J, Tamaskovic R, Yang Z, Brazil DP, Merlo A, Hess D, Hemmings BA. Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation. J Biol Chem. 2004; 279:35510-35517.
    • (2004) J Biol Chem , vol.279 , pp. 35510-35517
    • Feng, J.1    Tamaskovic, R.2    Yang, Z.3    Brazil, D.P.4    Merlo, A.5    Hess, D.6    Hemmings, B.A.7
  • 29
    • 34047245274 scopus 로고    scopus 로고
    • MEK-ERKmediated phosphorylation of Mdm2 at Ser-166 in hepatocytes. Mdm2 is activated in response to inhibited Akt signaling
    • Malmlof M, Roudier E, Hogberg J, Stenius U. MEK-ERKmediated phosphorylation of Mdm2 at Ser-166 in hepatocytes. Mdm2 is activated in response to inhibited Akt signaling. J Biol Chem. 2007; 282:2288-2296.
    • (2007) J Biol Chem , vol.282 , pp. 2288-2296
    • Malmlof, M.1    Roudier, E.2    Hogberg, J.3    Stenius, U.4
  • 30
    • 65049086892 scopus 로고    scopus 로고
    • Helicobacter pylori and gastric carcinogenesis
    • Hatakeyama M. Helicobacter pylori and gastric carcinogenesis. J Gastroenterol. 2009; 44:239-248.
    • (2009) J Gastroenterol , vol.44 , pp. 239-248
    • Hatakeyama, M.1
  • 32
    • 0034624678 scopus 로고    scopus 로고
    • Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase
    • Honda R, Yasuda H. Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase. Oncogene. 2000; 19:1473-1476.
    • (2000) Oncogene , vol.19 , pp. 1473-1476
    • Honda, R.1    Yasuda, H.2
  • 34
    • 27744471043 scopus 로고    scopus 로고
    • Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion
    • Suzuki M, Mimuro H, Suzuki T, Park M, Yamamoto T, Sasakawa C. Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion. J Exp Med. 2005; 202:1235-1247.
    • (2005) J Exp Med , vol.202 , pp. 1235-1247
    • Suzuki, M.1    Mimuro, H.2    Suzuki, T.3    Park, M.4    Yamamoto, T.5    Sasakawa, C.6
  • 35
    • 34548621770 scopus 로고    scopus 로고
    • CagA-independent disruption of adherence junction complexes involves E-cadherin shedding and implies multiple steps in Helicobacter pylori pathogenicity
    • Weydig C, Starzinski-Powitz A, Carra G, Lower J, Wessler S. CagA-independent disruption of adherence junction complexes involves E-cadherin shedding and implies multiple steps in Helicobacter pylori pathogenicity. Exp Cell Res. 2007; 313:3459-3471.
    • (2007) Exp Cell Res , vol.313 , pp. 3459-3471
    • Weydig, C.1    Starzinski-Powitz, A.2    Carra, G.3    Lower, J.4    Wessler, S.5
  • 36
    • 68849105814 scopus 로고    scopus 로고
    • Oncogenic stress sensed by the immune system: role of natural killer cell receptors
    • Raulet DH, Guerra N. Oncogenic stress sensed by the immune system: role of natural killer cell receptors. Nat Rev Immunol. 2009; 9:568-580.
    • (2009) Nat Rev Immunol , vol.9 , pp. 568-580
    • Raulet, D.H.1    Guerra, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.