Cold hypersensitivity increases with age in mice with sickle cell disease

Pain

Volumn 155, Issue 12, 2014, Pages 2476-2485

  Zappia, Katherine J ^a   Garrison, Sheldon R ^a   Hillery, Cheryl A ^a,b   Stucky, Cheryl L ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b BLOOD RESEARCH INSTITUTE   (United States)

Author keywords

Aging; C fiber; Endothelin 1; KCNK; TRPA1; TRPM8

Indexed keywords

ENDOTHELIN 1; ION CHANNEL; MESSENGER RNA; TACHYKININ RECEPTOR; TACHYKININ RECEPTOR 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; UNCLASSIFIED DRUG; HEMOGLOBIN A; HEMOGLOBIN AA; TANDEM PORE DOMAIN POTASSIUM CHANNEL; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY C, MEMBER 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM8 PROTEIN, MOUSE;

ADULT; AGED; AGING; ANIMAL MODEL; ARTICLE; CHRONIC PAIN; COLD SENSITIVITY; CONTROLLED STUDY; DISEASE SEVERITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; MALE; MOUSE; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; SENSORY NERVE; SICKLE CELL ANEMIA; SKIN SENSITIVITY; SPINAL GANGLION; ADVERSE EFFECTS; AGE; ANIMAL; C57BL MOUSE; COLD; COMPLICATION; CRYOPYRIN-ASSOCIATED PERIODIC SYNDROMES; GENE EXPRESSION REGULATION; GENETICS; IN VITRO STUDY; INNERVATION; METABOLISM; NONMYELINATED NERVE; PATHOLOGY; PHYSIOLOGY; SENSORY NERVE CELL; SKIN; TRANSGENIC MOUSE;

AGE FACTORS; AGING; ANEMIA, SICKLE CELL; ANIMALS; COLD TEMPERATURE; CRYOPYRIN-ASSOCIATED PERIODIC SYNDROMES; ENDOTHELIN-1; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; HEMOGLOBIN A; IN VITRO TECHNIQUES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NERVE FIBERS, UNMYELINATED; PAIN THRESHOLD; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; SENSORY RECEPTOR CELLS; SKIN; TRPC CATION CHANNELS; TRPM CATION CHANNELS;

EID: 84922744582     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2014.05.030     Document Type: Article

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