Neurosensory changes in a human model of endothelin-1 induced pain: A behavioral study

Neuroscience Letters

Volumn 418, Issue 2, 2007, Pages 117-121

  Hans, Guy ^a   Deseure, Kristof ^a   Robert, Dominique ^a   De Hert, Stefan ^a  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Cancer pain; Endothelin 1; Human; Intradermal injection

Indexed keywords

ENDOTHELIN 1; PLACEBO;

ADULT; ARTICLE; BEHAVIOR; CANCER PAIN; COLD; COLD SENSATION; CONTROLLED STUDY; EXPERIMENTAL MODEL; HEAT; HUMAN; HUMAN EXPERIMENT; HYPERALGESIA; HYPESTHESIA; MALE; NOCICEPTION; NORMAL HUMAN; PRIORITY JOURNAL; PSYCHOPHYSICS; SENSATION; STIMULATION; TEMPERATURE SENSE; THERMAL ANALYSIS;

ADULT; BEHAVIOR; BIOPHYSICS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; ENDOTHELIN-1; HUMANS; HYPERALGESIA; INJECTIONS, INTRADERMAL; MALE; MODELS, NEUROLOGICAL; NEOPLASMS; NOCICEPTORS; PAIN; RECEPTOR, ENDOTHELIN A; RECEPTORS, SENSORY; TEMPERATURE SENSE;

EID: 34247375640     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.03.008     Document Type: Article

References (36)

1. Ali Z., Meyer R.A., and Campbell J.N. Secondary hyperalgesia to mechanical but not heat stimuli following a capsaicin injection in hairy skin. Pain 68 2-3 (1996) 401-411
2. Balonov K., Khodorova A., and Strichartz G.R. Tactile allodynia initiated by local subcutaneous endothelin-1 is prolonged by activation of TRPV-1 receptors. Exp. Biol. Med. (Maywood) 231 6 (2006) 1165-1170
3. Brain S.D., Thomas G., Crossman D.C., Fuller R., and Church M.K. Endothelin-1 induces a histamine-dependent flare in vivo, but does not activate human skin mast cells in vitro. Br. J. Clin. Pharmacol. 33 1 (1992) 117-120
4. Brandli P., Loffler B.M., Breu V., Osterwalder R., Maire J.P., and Clozel M. Role of endothelin in mediating neurogenic plasma extravasation in rat dura mater. Pain 64 2 (1996) 315-322
5. Brennum J., Kaiser F., and Dahl J.B. Effect of naloxone on primary and secondary hyperalgesia induced by the human burn injury model. Acta Anaesthesiol. Scand. 45 8 (2001) 954-960
6. Bunker C.B., Coulson M.L., Hayes N.A., Dowd P.M., and Foreman J.C. Further studies on the actions of endothelin-1 on blood flow in human skin. Br. J. Dermatol. 127 2 (1992) 85-90
7. Caraceni A., and Portenoy R.K. An international survey of cancer pain characteristics and syndromes. IASP Task Force on Cancer Pain. International Association for the Study of Pain. Pain 82 3 (1999) 263-274
8. Chichorro J.G., Zampronio A.R., and Rae G.A. Endothelin ET(B) receptor antagonist reduces mechanical allodynia in rats with trigeminal neuropathic pain. Exp. Biol. Med. (Maywood) 231 6 (2006) 1136-1140
9. Chichorro J.G., Zampronio A.R., Souza G.E., and Rae G.A. Orofacial cold hyperalgesia due to infraorbital nerve constriction injury in rats: reversal by endothelin receptor antagonists but not non-steroidal anti-inflammatory drugs. Pain 123 1-2 (2006) 64-74
10. Chirgwin J.M., and Guise T.A. Molecular mechanisms of tumor-bone interactions in osteolytic metastases. Crit. Rev. Eukaryot. Gene Expr. 10 2 (2000) 159-178
11. Crossman D.C., Brain S.D., and Fuller R.W. Potent vasoactive properties of endothelin 1 in human skin. J. Appl. Physiol. 70 1 (1991) 260-266
12. Dahlof B., Gustafsson D., Hedner T., Jern S., and Hansson L. Regional haemodynamic effects of endothelin-1 in rat and man: unexpected adverse reaction. J. Hypertens. 8 9 (1990) 811-817
13. Davar G., Hans G., Fareed M.U., Sinnott C., and Strichartz G. Behavioral signs of acute pain produced by application of endothelin-1 to rat sciatic nerve. Neuroreport 9 10 (1998) 2279-2283
14. Ferreira S.H., Romitelli M., and de Nucci G. Endothelin-1 participation in overt and inflammatory pain. J. Cardiovasc. Pharmacol. 13 Suppl. 5 (1989) S220-S222
15. Fuchs P.N., Meyer R.A., and Raja S.N. Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin. Pain 90 1-2 (2001) 15-23
16. Gokin A.P., Fareed M.U., Pan H.L., Hans G., Strichartz G.R., and Davar G. Local injection of endothelin-1 produces pain-like behavior and excitation of nociceptors in rats. J. Neurosci. 21 14 (2001) 5358-5366
17. Grant K., Loizidou M., and Taylor I. Endothelin-1: a multifunctional molecule in cancer. Br. J. Cancer 88 2 (2003) 163-166
18. Hall T.C. Paraneoplastic syndromes: mechanisms. Semin. Oncol. 24 3 (1997) 269-276
19. Katugampola R., Church M.K., and Clough G.F. The neurogenic vasodilator response to endothelin-1: a study in human skin in vivo. Exp. Physiol. 85 6 (2000) 839-846
20. Khodorova A., Navarro B., Jouaville L.S., Murphy J.E., Rice F.L., Mazurkiewicz J.E., Long-Woodward D., Stoffel M., Strichartz G.R., Yukhananov R., and Davar G. Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injury. Nat. Med. 9 8 (2003) 1055-1061
21. Klede M., Handwerker H.O., and Schmelz M. Central origin of secondary mechanical hyperalgesia. J. Neurophysiol. 90 1 (2003) 353-359
22. Kusuhara M., Yamaguchi K., Nagasaki K., Hayashi C., Suzaki A., Hori S., Handa S., Nakamura Y., and Abe K. Production of endothelin in human cancer cell lines. Cancer Res. 50 11 (1990) 3257-3261
23. Leslie S.J., Rahman M.Q., Denvir M.A., Newby D.E., and Webb D.J. Endothelins and their inhibition in the human skin microcirculation: ET[1-31], a new vasoconstrictor peptide. Br. J. Clin. Pharmacol. 57 6 (2004) 720-725
24. May A., Gijsman H.J., Wallnofer A., Jones R., Diener H.C., and Ferrari M.D. Endothelin antagonist bosentan blocks neurogenic inflammation, but is not effective in aborting migraine attacks. Pain 67 2-3 (1996) 375-378
25. Menendez L., Lastra A., Hidalgo A., and Baamonde A. Nociceptive reaction and thermal hyperalgesia induced by local ET-1 in mice: a behavioral and Fos study. Naunyn. Schmiedebergs Arch. Pharmacol. 367 1 (2003) 28-34
26. Motta E.M., Calixto J.B., and Rae G.A. Mechanical hyperalgesia induced by endothelin-1 in rats is mediated via phospholipase C, protein kinase C, and MAP kinases. Exp. Biol. Med. (Maywood) 231 6 (2006) 1141-1145
27. Nakayama M., Takahashi K., Hara E., Murakami O., Totsune K., Sone M., Satoh F., and Shibahara S. Production and secretion of two vasoactive peptides, endothelin-1 and adrenomedullin, by a colorectal adenocarcinoma cell line, DLD-1. J. Cardiovasc. Pharmacol. 31 Suppl. 1 (1998) S534-S536
28. Piovezan A.P., D'Orleans-Juste P., Frighetto M., Souza G.E., Henriques M.G., and Rae G.A. Effects of endothelin-1 on capsaicin-induced nociception in mice. Eur. J. Pharmacol. 351 1 (1998) 15-22
29. Piovezan A.P., D'Orleans-Juste P., Tonussi C.R., and Rae G.A. Endothelins contribute towards nociception induced by antigen in ovalbumin-sensitised mice. Br. J. Pharmacol. 141 4 (2004) 755-763
30. Raffa R.B., Schupsky J.J., and Jacoby H.I. Endothelin-induced nociception in mice: mediation by ETA and ETB receptors. J. Pharmacol. Exp. Ther. 276 2 (1996) 647-651
31. Schmelz M., Schmidt R., Weidner C., Hilliges M., Torebjork H.E., and Handwerker H.O. Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens. J. Neurophysiol. 89 5 (2003) 2441-2448
32. Shankar A., Loizidou M., Aliev G., Fredericks S., Holt D., Boulos P.B., Burnstock G., and Taylor I. Raised endothelin 1 levels in patients with colorectal liver metastases. Br. J. Surg. 85 4 (1998) 502-506
33. Takahashi K., Sato J., and Mizumura K. Responses of C-fiber low threshold mechanoreceptors and nociceptors to cold were facilitated in rats persistently inflamed and hypersensitive to cold. Neurosci. Res. 47 4 (2003) 409-419
34. Wang Q.B., Qu W.S., Qin D.S., and Wang Z.P. Roles of endothelin and its receptors in prostate cancer. Zhonghua Nan Ke Xue 12 5 (2006) 450-452
35. Zambreanu L., Wise R.G., Brooks J.C., Iannetti G.D., and Tracey I. A role for the brainstem in central sensitisation in humans. Evidence from functional magnetic resonance imaging. Pain 114 3 (2005) 397-407
36. Zhou Q.L., Strichartz G., and Davar G. Endothelin-1 activates ET(A) receptors to increase intracellular calcium in model sensory neurons. Neuroreport 12 17 (2001) 3853-3857