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Volumn 107, Issue 3, 2012, Pages 913-922

TRPC1 contributes to light-touch sensation and mechanical responses in low-threshold cutaneous sensory neurons

Author keywords

A fiber; C fiber; Nociceptor; Pain; Transient receptor potential; TRPA1

Indexed keywords

TRANSIENT RECEPTOR POTENTIAL CHANNEL 1;

EID: 84855837580     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00658.2011     Document Type: Article
Times cited : (70)

References (56)
  • 1
    • 66049108304 scopus 로고    scopus 로고
    • TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization
    • Alessandri-Haber N, Dina OA, Chen X, Levine JD. TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization. J Neurosci 29: 6217-6228, 2009.
    • (2009) J Neurosci , vol.29 , pp. 6217-6228
    • Alessandri-Haber, N.1    Dina, O.A.2    Chen, X.3    Levine, J.D.4
  • 2
    • 24644459285 scopus 로고    scopus 로고
    • Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor
    • Braz JM, Nassar MA, Wood JN, Basbaum AI. Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor. Neuron 47: 787-793, 2005.
    • (2005) Neuron , vol.47 , pp. 787-793
    • Braz, J.M.1    Nassar, M.A.2    Wood, J.N.3    Basbaum, A.I.4
  • 3
    • 17044399313 scopus 로고    scopus 로고
    • Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse
    • Breese NM, George AC, Pauers LE, Stucky CL. Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse. Pain 115: 37-49, 2005.
    • (2005) Pain , vol.115 , pp. 37-49
    • Breese, N.M.1    George, A.C.2    Pauers, L.E.3    Stucky, C.L.4
  • 5
    • 0017763282 scopus 로고
    • The morphology of hair follicle afferent fibre collaterals in the spinal cord of the cat
    • Brown AG, Rose PK, Snow PJ. The morphology of hair follicle afferent fibre collaterals in the spinal cord of the cat. J Physiol 272: 779-797, 1977.
    • (1977) J Physiol , vol.272 , pp. 779-797
    • Brown, A.G.1    Rose, P.K.2    Snow, P.J.3
  • 8
    • 79959773002 scopus 로고    scopus 로고
    • Contribution of TRPC1 and Orai1 to Ca(2+) entry activated by store depletion
    • Cheng KT, Ong HL, Liu X, Ambudkar IS. Contribution of TRPC1 and Orai1 to Ca(2+) entry activated by store depletion. Adv Exp Med Biol 704: 435-449, 2011.
    • (2011) Adv Exp Med Biol , vol.704 , pp. 435-449
    • Cheng, K.T.1    Ong, H.L.2    Liu, X.3    Ambudkar, I.S.4
  • 11
    • 0018867072 scopus 로고
    • Efficient analysis of experimental observations
    • Dixon WJ. Efficient analysis of experimental observations. Annu Rev Pharmacol Toxicol 20: 441-462, 1980.
    • (1980) Annu Rev Pharmacol Toxicol , vol.20 , pp. 441-462
    • Dixon, W.J.1
  • 12
    • 16644365574 scopus 로고    scopus 로고
    • Abeta-fiber nociceptive primary afferent neurons: A review of incidence and properties in relation to other afferent A-fiber neurons in mammals
    • Djouhri L, Lawson SN. Abeta-fiber nociceptive primary afferent neurons: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals. Brain Res Brain Res Rev 46: 131-145, 2004.
    • (2004) Brain Res Brain Res Rev , vol.46 , pp. 131-145
    • Djouhri, L.1    Lawson, S.N.2
  • 13
    • 1842425673 scopus 로고    scopus 로고
    • Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1
    • Dohke Y, Oh YS, Ambudkar IS, Turner RJ. Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1. J Biol Chem 279: 12242-12248, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 12242-12248
    • Dohke, Y.1    Oh, Y.S.2    Ambudkar, I.S.3    Turner, R.J.4
  • 14
    • 34347394137 scopus 로고    scopus 로고
    • Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion
    • Elg S, Marmigere F, Mattsson JP, Ernfors P. Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion. J Comp Neurol 503: 35-46, 2007.
    • (2007) J Comp Neurol , vol.503 , pp. 35-46
    • Elg, S.1    Marmigere, F.2    Mattsson, J.P.3    Ernfors, P.4
  • 18
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves K, Dubner R, Brown F, Flores C, Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32: 77-88, 1988.
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 19
    • 77951711519 scopus 로고    scopus 로고
    • Stretch-activated cation channel from larval bullfrog skin
    • Hillyard SD, Willumsen NJ, Marrero MB. Stretch-activated cation channel from larval bullfrog skin. J Exp Biol 213: 1782-1787, 2010.
    • (2010) J Exp Biol , vol.213 , pp. 1782-1787
    • Hillyard, S.D.1    Willumsen, N.J.2    Marrero, M.B.3
  • 20
    • 2442625209 scopus 로고    scopus 로고
    • Essential components for a glutamatergic synapse between Merkel cell and nerve terminal in rats
    • Hitchcock IS, Genever PG, Cahusac PM. Essential components for a glutamatergic synapse between Merkel cell and nerve terminal in rats. Neurosci Lett 362: 196-199, 2004.
    • (2004) Neurosci Lett , vol.362 , pp. 196-199
    • Hitchcock, I.S.1    Genever, P.G.2    Cahusac, P.M.3
  • 21
    • 0037188517 scopus 로고    scopus 로고
    • Subunit composition of mammalian transient receptor potential channels in living cells
    • Hofmann T, Schaefer M, Schultz G, Gudermann T. Subunit composition of mammalian transient receptor potential channels in living cells. Proc Natl Acad Sci USA 99: 7461-7466, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7461-7466
    • Hofmann, T.1    Schaefer, M.2    Schultz, G.3    Gudermann, T.4
  • 22
    • 58149396234 scopus 로고    scopus 로고
    • Overexpressed transient receptor potential vanilloid 3 ion channels in skin keratinocytes modulate pain sensitivity via prostaglandin E2
    • Huang SM, Lee H, Chung MK, Park U, Yu YY, Bradshaw HB, Coulombe PA, Walker JM, Caterina MJ. Overexpressed transient receptor potential vanilloid 3 ion channels in skin keratinocytes modulate pain sensitivity via prostaglandin E2. J Neurosci 28: 13727-13737, 2008.
    • (2008) J Neurosci , vol.28 , pp. 13727-13737
    • Huang, S.M.1    Lee, H.2    Chung, M.K.3    Park, U.4    Yu, Y.Y.5    Bradshaw, H.B.6    Coulombe, P.A.7    Walker, J.M.8    Caterina, M.J.9
  • 23
    • 65649141656 scopus 로고    scopus 로고
    • Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors
    • Kerstein PC, del Camino D, Moran MM, Stucky CL. Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors. Mol Pain 5: 19, 2009.
    • (2009) Mol Pain , vol.5 , pp. 19
    • Kerstein, P.C.1    del Camino, D.2    Moran, M.M.3    Stucky, C.L.4
  • 24
    • 72149113587 scopus 로고    scopus 로고
    • The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement
    • Kobori T, Smith GD, Sandford R, Edwardson JM. The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement. J Biol Chem 284: 35507-35513, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 35507-35513
    • Kobori, T.1    Smith, G.D.2    Sandford, R.3    Edwardson, J.M.4
  • 25
    • 0030680084 scopus 로고    scopus 로고
    • Receptive properties of embryonic chick sensory neurons innervating skin
    • Koltzenburg M, Lewin GR. Receptive properties of embryonic chick sensory neurons innervating skin. J Neurophysiol 78: 2560-2568, 1997.
    • (1997) J Neurophysiol , vol.78 , pp. 2560-2568
    • Koltzenburg, M.1    Lewin, G.R.2
  • 26
    • 0031932427 scopus 로고    scopus 로고
    • Sensory changes in adults with unilateral transtibial amputation
    • Kosasih JB, Silver-Thorn MB. Sensory changes in adults with unilateral transtibial amputation. J Rehabil Res Dev 35: 85-90, 1998.
    • (1998) J Rehabil Res Dev , vol.35 , pp. 85-90
    • Kosasih, J.B.1    Silver-Thorn, M.B.2
  • 27
    • 65549123596 scopus 로고    scopus 로고
    • TRPA1 modulates mechanotransduction in cutaneous sensory neurons
    • Kwan KY, Glazer JM, Corey DP, Rice FL, Stucky CL. TRPA1 modulates mechanotransduction in cutaneous sensory neurons. J Neurosci 29: 4808-4819, 2009.
    • (2009) J Neurosci , vol.29 , pp. 4808-4819
    • Kwan, K.Y.1    Glazer, J.M.2    Corey, D.P.3    Rice, F.L.4    Stucky, C.L.5
  • 28
    • 79952055407 scopus 로고    scopus 로고
    • Reduced TRPC channel expression in psoriatic keratinocytes is associated with impaired differentiation and enhanced proliferation
    • Leuner K, Kraus M, Woelfle U, Beschmann H, Harteneck C, Boehncke WH, Schempp CM, Muller WE. Reduced TRPC channel expression in psoriatic keratinocytes is associated with impaired differentiation and enhanced proliferation. PLos One 6: e14716, 2011.
    • (2011) PLos One , vol.6
    • Leuner, K.1    Kraus, M.2    Woelfle, U.3    Beschmann, H.4    Harteneck, C.5    Boehncke, W.H.6    Schempp, C.M.7    Muller, W.E.8
  • 29
    • 67649479256 scopus 로고    scopus 로고
    • The role of enhanced cutaneous IL-1beta signaling in a rat tibia fracture model of complex regional pain syndrome
    • Li WW, Sabsovich I, Guo TZ, Zhao R, Kingery WS, Clark JD. The role of enhanced cutaneous IL-1beta signaling in a rat tibia fracture model of complex regional pain syndrome. Pain 144: 303-313, 2009.
    • (2009) Pain , vol.144 , pp. 303-313
    • Li, W.W.1    Sabsovich, I.2    Guo, T.Z.3    Zhao, R.4    Kingery, W.S.5    Clark, J.D.6
  • 30
    • 20444364145 scopus 로고    scopus 로고
    • Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel. Heteromeric assembly of TRPC1-TRPC3
    • Liu X, Bandyopadhyay BC, Singh BB, Groschner K, Ambudkar IS. Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel. Heteromeric assembly of TRPC1-TRPC3. J Biol Chem 280: 21600-21606, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 21600-21606
    • Liu, X.1    Bandyopadhyay, B.C.2    Singh, B.B.3    Groschner, K.4    Ambudkar, I.S.5
  • 31
    • 80052532253 scopus 로고    scopus 로고
    • Electrophysiological properties of heteromeric TRPV4-C1 channels
    • Ma X, Nilius B, Wong JW, Huang Y, Yao X. Electrophysiological properties of heteromeric TRPV4-C1 channels. Biochim Biophys Acta 1808: 2789-2797, 2011.
    • (2011) Biochim Biophys Acta , vol.1808 , pp. 2789-2797
    • Ma, X.1    Nilius, B.2    Wong, J.W.3    Huang, Y.4    Yao, X.5
  • 34
    • 34848883595 scopus 로고    scopus 로고
    • Overexpression of neurotrophin-3 enhances the mechanical response properties of slowly adapting type 1 afferents and myelinated nociceptors
    • McIlwrath SL, Lawson JJ, Anderson CE, Albers KM, Koerber HR. Overexpression of neurotrophin-3 enhances the mechanical response properties of slowly adapting type 1 afferents and myelinated nociceptors. Eur J Neurosci 26: 1801-1812, 2007.
    • (2007) Eur J Neurosci , vol.26 , pp. 1801-1812
    • McIlwrath, S.L.1    Lawson, J.J.2    Anderson, C.E.3    Albers, K.M.4    Koerber, H.R.5
  • 35
    • 79960377146 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 4 (TRPV4)-dependent calcium influx and ATP release in mouse esophageal keratinocytes
    • Mihara H, Boudaka A, Sugiyama T, Moriyama Y, Tominaga M. Transient receptor potential vanilloid 4 (TRPV4)-dependent calcium influx and ATP release in mouse esophageal keratinocytes. J Physiol 589: 3471-3482, 2011.
    • (2011) J Physiol , vol.589 , pp. 3471-3482
    • Mihara, H.1    Boudaka, A.2    Sugiyama, T.3    Moriyama, Y.4    Tominaga, M.5
  • 36
    • 0025330176 scopus 로고
    • Low-threshold mechanoreceptive and nociceptive units with unmyelinated (C) fibres in the human supraorbital nerve
    • Nordin M. Low-threshold mechanoreceptive and nociceptive units with unmyelinated (C) fibres in the human supraorbital nerve. J Physiol 426: 229-240, 1990.
    • (1990) J Physiol , vol.426 , pp. 229-240
    • Nordin, M.1
  • 37
    • 33749500948 scopus 로고    scopus 로고
    • Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: A potential role for TRPC1 in Darier's disease
    • Pani B, Cornatzer E, Cornatzer W, Shin DM, Pittelkow MR, Hovnanian A, Ambudkar IS, Singh BB. Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: a potential role for TRPC1 in Darier's disease. Mol Biol Cell 17: 4446-4458, 2006.
    • (2006) Mol Biol Cell , vol.17 , pp. 4446-4458
    • Pani, B.1    Cornatzer, E.2    Cornatzer, W.3    Shin, D.M.4    Pittelkow, M.R.5    Hovnanian, A.6    Ambudkar, I.S.7    Singh, B.B.8
  • 38
    • 0009832893 scopus 로고
    • Sensory receptors in a mammalian skin-nerve in vitro preparation
    • Reeh PW. Sensory receptors in a mammalian skin-nerve in vitro preparation. Prog Brain Res 74: 271-276, 1988.
    • (1988) Prog Brain Res , vol.74 , pp. 271-276
    • Reeh, P.W.1
  • 39
    • 33846922037 scopus 로고    scopus 로고
    • TRPC1 Ca(2+)-permeable channels in animal cells
    • Rychkov G, Barritt GJ. TRPC1 Ca(2+)-permeable channels in animal cells. Handb Exp Pharmacol 23-52, 2007.
    • (2007) Handb Exp Pharmacol , pp. 23-52
    • Rychkov, G.1    Barritt, G.J.2
  • 40
    • 0025165445 scopus 로고
    • Selective neuronal glycoconjugate expression in sensory and autonomic ganglia: Relation of lectin reactivity to peptide and enzyme markers
    • Silverman JD, Kruger L. Selective neuronal glycoconjugate expression in sensory and autonomic ganglia: relation of lectin reactivity to peptide and enzyme markers. J Neurocytol 19: 789-801, 1990.
    • (1990) J Neurocytol , vol.19 , pp. 789-801
    • Silverman, J.D.1    Kruger, L.2
  • 42
    • 67349203593 scopus 로고    scopus 로고
    • Downregulation of TRPC1 by shRNA reduces mechanosensitivity in mouse dorsal root ganglion neurons in vitro
    • Staaf S, Maxvall I, Lind U, Husmark J, Mattsson JP, Ernfors P, Pierrou S. Downregulation of TRPC1 by shRNA reduces mechanosensitivity in mouse dorsal root ganglion neurons in vitro. Neurosci Lett 457: 3-7, 2009.
    • (2009) Neurosci Lett , vol.457 , pp. 3-7
    • Staaf, S.1    Maxvall, I.2    Lind, U.3    Husmark, J.4    Mattsson, J.P.5    Ernfors, P.6    Pierrou, S.7
  • 43
    • 0022359013 scopus 로고
    • Sensory receptors with unmyelinated (C) fibers innervating the skin of the rabbit's ear
    • Shea VK, Perl ER. Sensory receptors with unmyelinated (C) fibers innervating the skin of the rabbit's ear. J Neurophysiol 54: 491-501, 1985.
    • (1985) J Neurophysiol , vol.54 , pp. 491-501
    • Shea, V.K.1    Perl, E.R.2
  • 44
    • 77955667713 scopus 로고    scopus 로고
    • Atomic force microscopy reveals the alternating subunit arrangement of the TRPP2- TRPV4 heterotetramer
    • Stewart AP, Smith GD, Sandford RN, Edwardson JM. Atomic force microscopy reveals the alternating subunit arrangement of the TRPP2- TRPV4 heterotetramer. Biophys J 99: 790-797, 2010.
    • (2010) Biophys J , vol.99 , pp. 790-797
    • Stewart, A.P.1    Smith, G.D.2    Sandford, R.N.3    Edwardson, J.M.4
  • 45
    • 0035051978 scopus 로고    scopus 로고
    • TRPC1 and TRPC5 form a novel cation channel in mammalian brain
    • Strubing C, Krapivinsky G, Krapivinsky L, Clapham DE. TRPC1 and TRPC5 form a novel cation channel in mammalian brain. Neuron 29: 645-655, 2001.
    • (2001) Neuron , vol.29 , pp. 645-655
    • Strubing, C.1    Krapivinsky, G.2    Krapivinsky, L.3    Clapham, D.E.4
  • 46
    • 0033178342 scopus 로고    scopus 로고
    • Isolectin B4-positive and -negative nociceptors are functionally distinct
    • Stucky CL, Lewin GR. Isolectin B4-positive and -negative nociceptors are functionally distinct. J Neurosci 19: 6497-6505, 1999.
    • (1999) J Neurosci , vol.19 , pp. 6497-6505
    • Stucky, C.L.1    Lewin, G.R.2
  • 47
    • 0022981156 scopus 로고
    • Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin
    • Sugiura Y, Lee CL, Perl ER. Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin. Science 234: 358-361, 1986.
    • (1986) Science , vol.234 , pp. 358-361
    • Sugiura, Y.1    Lee, C.L.2    Perl, E.R.3
  • 48
    • 0027319508 scopus 로고
    • Dissociated secondary hyperalgesia in a subject with a large-fibre sensory neuropathy
    • Treede RD, Cole JD. Dissociated secondary hyperalgesia in a subject with a large-fibre sensory neuropathy. Pain 53: 169-174, 1993.
    • (1993) Pain , vol.53 , pp. 169-174
    • Treede, R.D.1    Cole, J.D.2
  • 49
    • 70350037578 scopus 로고    scopus 로고
    • Mechanical- stimulation-evoked calcium waves in proliferating and differentiated human keratinocytes
    • Tsutsumi M, Inoue K, Denda S, Ikeyama K, Goto M, Denda M. Mechanical- stimulation-evoked calcium waves in proliferating and differentiated human keratinocytes. Cell Tissue Res 338: 99-106, 2009.
    • (2009) Cell Tissue Res , vol.338 , pp. 99-106
    • Tsutsumi, M.1    Inoue, K.2    Denda, S.3    Ikeyama, K.4    Goto, M.5    Denda, M.6
  • 50
    • 11944274809 scopus 로고    scopus 로고
    • Phospholipase cgammal is required for activation of store-operated channels in human keratinocytes
    • Tu CL, Chang W, Bikle DD. Phospholipase cgammal is required for activation of store-operated channels in human keratinocytes. J Invest Dermatol 124: 187-197, 2005.
    • (2005) J Invest Dermatol , vol.124 , pp. 187-197
    • Tu, C.L.1    Chang, W.2    Bikle, D.D.3
  • 51
    • 77952742033 scopus 로고    scopus 로고
    • Spinal nerve ligation in mouse upregulates TRPV1 heat function in injured IB4-positive nociceptors
    • Vilceanu D, Honore P, Hogan QH, Stucky CL. Spinal nerve ligation in mouse upregulates TRPV1 heat function in injured IB4-positive nociceptors. J Pain 11: 588-599, 2010.
    • (2010) J Pain , vol.11 , pp. 588-599
    • Vilceanu, D.1    Honore, P.2    Hogan, Q.H.3    Stucky, C.L.4
  • 52
    • 0035576403 scopus 로고    scopus 로고
    • Functional interactions between tumor and peripheral nerve: Morphology, algogen identification, and behavioral characterization of a new murine model of cancer pain
    • Wacnik PW, Eikmeier LJ, Ruggles TR, Ramnaraine ML, Walcheck BK, Beitz AJ, Wilcox GL. Functional interactions between tumor and peripheral nerve: morphology, algogen identification, and behavioral characterization of a new murine model of cancer pain. J Neurosci 21: 9355-9366, 2001.
    • (2001) J Neurosci , vol.21 , pp. 9355-9366
    • Wacnik, P.W.1    Eikmeier, L.J.2    Ruggles, T.R.3    Ramnaraine, M.L.4    Walcheck, B.K.5    Beitz, A.J.6    Wilcox, G.L.7
  • 53
    • 42449159261 scopus 로고    scopus 로고
    • Identity of myelinated cutaneous sensory neurons projecting to nocireceptive laminae following nerve injury in adult mice
    • Woodbury CJ, Kullmann FA, McIlwrath SL, Koerber HR. Identity of myelinated cutaneous sensory neurons projecting to nocireceptive laminae following nerve injury in adult mice. J Comp Neurol 508: 500-509, 2008.
    • (2008) J Comp Neurol , vol.508 , pp. 500-509
    • Woodbury, C.J.1    Kullmann, F.A.2    McIlwrath, S.L.3    Koerber, H.R.4
  • 54
    • 0026555273 scopus 로고
    • Peripheral nerve injury triggers central sprouting of myelinated afferents
    • Woolf CJ, Shortland P, Coggeshall RE. Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature 355: 75-78, 1992.
    • (1992) Nature , vol.355 , pp. 75-78
    • Woolf, C.J.1    Shortland, P.2    Coggeshall, R.E.3
  • 55
    • 77954064264 scopus 로고    scopus 로고
    • Changes in Abeta non-nociceptive primary sensory neurons in a rat model of osteoarthritis pain
    • Wu Q, Henry JL. Changes in Abeta non-nociceptive primary sensory neurons in a rat model of osteoarthritis pain. Mol Pain 6: 37, 2010.
    • (2010) Mol Pain , vol.6 , pp. 37
    • Wu, Q.1    Henry, J.L.2
  • 56
    • 75349088408 scopus 로고    scopus 로고
    • Delayed onset of changes in soma action potential genesis in nociceptive A-beta DRG neurons in vivo in a rat model of osteoarthritis
    • Wu Q, Henry JL. Delayed onset of changes in soma action potential genesis in nociceptive A-beta DRG neurons in vivo in a rat model of osteoarthritis. Mol Pain 5: 57, 2009.
    • (2009) Mol Pain , vol.5 , pp. 57
    • Wu, Q.1    Henry, J.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.