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Volumn 40, Issue 2, 2015, Pages 293-300

Changes of the Thioredoxin System, Glutathione Peroxidase Activity and Total Antioxidant Capacity in Rat Brain Cortex During Acute Liver Failure: Modulation by l-histidine

Author keywords

Glutathione peroxidase; Hepatic encephalopathy; Histidine; Oxidative nitrosative stress; Thioredoxin; Total antioxidant capacity

Indexed keywords

ANTIOXIDANT; GLUTATHIONE PEROXIDASE; HISTIDINE; MESSENGER RNA; PROTEIN; THIOACETAMIDE; THIOREDOXIN; THIOREDOXIN INTERACTING PROTEIN; THIOREDOXIN REDUCTASE; TRIP PROTEIN; UNCLASSIFIED DRUG;

EID: 84922728145     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1417-9     Document Type: Article
Times cited : (18)

References (57)
  • 1
    • 0033055873 scopus 로고    scopus 로고
    • Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration
    • COI: 1:STN:280:DyaK1M7mt1emsA%3D%3D, PID: 10051463
    • Clemmesen JO, Larsen FS, Kondruo JK, Hansen BA, Ott P (1999) Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration. Hepatology 29:648–653
    • (1999) Hepatology , vol.29 , pp. 648-653
    • Clemmesen, J.O.1    Larsen, F.S.2    Kondruo, J.K.3    Hansen, B.A.4    Ott, P.5
  • 2
    • 37749006615 scopus 로고    scopus 로고
    • Arterial ammonia and clinical risk factors for encephalopathy and intracranial hypertension in acute liver failure
    • COI: 1:CAS:528:DC%2BD2sXhsVGiur%2FL, PID: 17685471
    • Bernal W, Hall C, Karvellas CJ, Auzinger G, Sizer E, Wendon J (2007) Arterial ammonia and clinical risk factors for encephalopathy and intracranial hypertension in acute liver failure. Hepatology 46:1844–1852
    • (2007) Hepatology , vol.46 , pp. 1844-1852
    • Bernal, W.1    Hall, C.2    Karvellas, C.J.3    Auzinger, G.4    Sizer, E.5    Wendon, J.6
  • 3
    • 0024406907 scopus 로고
    • Electron microscopic study of the blood–brain barrier in rats with brain edema and encephalopathy due to acute hepatic failure
    • COI: 1:STN:280:DyaL1Mzgs1emtw%3D%3D, PID: 2744330
    • Kato M, Sugihara J, Nakamura T, Muto Y (1989) Electron microscopic study of the blood–brain barrier in rats with brain edema and encephalopathy due to acute hepatic failure. Gastroenterol Jpn 24:135–142
    • (1989) Gastroenterol Jpn , vol.24 , pp. 135-142
    • Kato, M.1    Sugihara, J.2    Nakamura, T.3    Muto, Y.4
  • 4
    • 4644341574 scopus 로고    scopus 로고
    • Pathogenesis of intracranial hypertension in acute liver failure: inflammation, ammonia and cerebral blood flow
    • COI: 1:CAS:528:DC%2BD2cXotF2isLg%3D, PID: 15464242
    • Jalan R, Alde Damink SW, Hayes PC, Deutz NE, Lee A (2004) Pathogenesis of intracranial hypertension in acute liver failure: inflammation, ammonia and cerebral blood flow. J Hepatol 41:613–620
    • (2004) J Hepatol , vol.41 , pp. 613-620
    • Jalan, R.1    Alde Damink, S.W.2    Hayes, P.C.3    Deutz, N.E.4    Lee, A.5
  • 6
    • 29744439959 scopus 로고    scopus 로고
    • Protein tyrosine nitration in hyperammonemia and hepatic encephalopathy
    • PID: 16382339
    • Häussinger D, Görg B, Reinehr R, Schliess F (2005) Protein tyrosine nitration in hyperammonemia and hepatic encephalopathy. Metab Brain Dis 20:285–294
    • (2005) Metab Brain Dis , vol.20 , pp. 285-294
    • Häussinger, D.1    Görg, B.2    Reinehr, R.3    Schliess, F.4
  • 7
    • 33646176782 scopus 로고    scopus 로고
    • Membrane alterations and fluidity changes in cerebral cortex during acute ammonia intoxication
    • COI: 1:CAS:528:DC%2BD28XksVCltL4%3D, PID: 16430963
    • Swapna I, Sathya Sai Kumar KV, Murthy ChR, Senthilkumaran B (2006) Membrane alterations and fluidity changes in cerebral cortex during acute ammonia intoxication. Neurotoxicology 27:402–408
    • (2006) Neurotoxicology , vol.27 , pp. 402-408
    • Swapna, I.1    Sathya Sai Kumar, K.V.2    Murthy, C.R.3    Senthilkumaran, B.4
  • 9
    • 0036829813 scopus 로고    scopus 로고
    • Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients
    • PID: 12395325
    • Corbalán R, Chatauret N, Behrends S, Butterworth RF, Felipo V (2002) Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients. Hepatology 36:1155–1162
    • (2002) Hepatology , vol.36 , pp. 1155-1162
    • Corbalán, R.1    Chatauret, N.2    Behrends, S.3    Butterworth, R.F.4    Felipo, V.5
  • 10
    • 84875706447 scopus 로고    scopus 로고
    • Oxidative and nitrosative stress in ammonia neurotoxicity
    • PID: 23142151
    • Skowrońska M, Albrecht J (2013) Oxidative and nitrosative stress in ammonia neurotoxicity. Neurochem Int 62:731–737
    • (2013) Neurochem Int , vol.62 , pp. 731-737
    • Skowrońska, M.1    Albrecht, J.2
  • 11
    • 20544457990 scopus 로고    scopus 로고
    • Mechanisms of ammonia-induced cell death in rat cortical neurons: roles of NMDA receptors and glutathione
    • COI: 1:CAS:528:DC%2BD2MXlsl2ktLg%3D, PID: 15985217
    • Klejman A, Węgrzynowicz M, Szatmari EM, Mioduszewska B, Hetman M, Albrecht J (2005) Mechanisms of ammonia-induced cell death in rat cortical neurons: roles of NMDA receptors and glutathione. Neurochem Int 47:51–57
    • (2005) Neurochem Int , vol.47 , pp. 51-57
    • Klejman, A.1    Węgrzynowicz, M.2    Szatmari, E.M.3    Mioduszewska, B.4    Hetman, M.5    Albrecht, J.6
  • 12
    • 0034257048 scopus 로고    scopus 로고
    • Elevation of glutathione levels by ammonium ions in primary cultures of rat astrocytes
    • COI: 1:CAS:528:DC%2BD3cXksF2gtrc%3D, PID: 10812211
    • Murthy ChR, Bender AS, Dombro RS, Bai G, Norenberg MD (2000) Elevation of glutathione levels by ammonium ions in primary cultures of rat astrocytes. Neurochem Int 37:255–268
    • (2000) Neurochem Int , vol.37 , pp. 255-268
    • Murthy, C.R.1    Bender, A.S.2    Dombro, R.S.3    Bai, G.4    Norenberg, M.D.5
  • 13
    • 34250728449 scopus 로고    scopus 로고
    • Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake
    • PID: 17239489
    • Węgrzynowicz M, Hilgier W, Dybel A, Oja SS, Saransaari P, Albrecht J (2007) Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake. Neurochem Int 50:883–889
    • (2007) Neurochem Int , vol.50 , pp. 883-889
    • Węgrzynowicz, M.1    Hilgier, W.2    Dybel, A.3    Oja, S.S.4    Saransaari, P.5    Albrecht, J.6
  • 14
    • 77955874347 scopus 로고    scopus 로고
    • Direct exposure to ammonia and hyperammonemia increase the extracellular accumulation and degradation of astroglia-derived glutathione in the rat prefrontal cortex
    • COI: 1:CAS:528:DC%2BC3cXhtVGrtLjI, PID: 20530233
    • Hilgier W, Węgrzynowicz M, Ruszkiewicz J, Oja SS, Saransaari P, Albrecht J (2010) Direct exposure to ammonia and hyperammonemia increase the extracellular accumulation and degradation of astroglia-derived glutathione in the rat prefrontal cortex. Toxicol Sci 117:163–168
    • (2010) Toxicol Sci , vol.117 , pp. 163-168
    • Hilgier, W.1    Węgrzynowicz, M.2    Ruszkiewicz, J.3    Oja, S.S.4    Saransaari, P.5    Albrecht, J.6
  • 15
    • 84873410890 scopus 로고    scopus 로고
    • Decrease of glutathione content in the prefrontal cortical mitochondria of rats with acute hepatic encephalopathy: prevention by histidine
    • COI: 1:CAS:528:DC%2BC3sXitFeku7s%3D, PID: 23086200
    • Ruszkiewicz J, Fręśko I, Hilgier W, Albrecht J (2013) Decrease of glutathione content in the prefrontal cortical mitochondria of rats with acute hepatic encephalopathy: prevention by histidine. Metab Brain Dis 28:11–14
    • (2013) Metab Brain Dis , vol.28 , pp. 11-14
    • Ruszkiewicz, J.1    Fręśko, I.2    Hilgier, W.3    Albrecht, J.4
  • 16
    • 0031949404 scopus 로고    scopus 로고
    • Nitroarginie, an inhibitor of nitric oxide synthase, prevents changes in superoxide radical and antioxidant enzymes induced by ammonia intoxication
    • Kosenko E, Kaminsky Y, Lopata O, Muravyov N, Kaminsky A, Hermenegildo C, Felipo V (1998) Nitroarginie, an inhibitor of nitric oxide synthase, prevents changes in superoxide radical and antioxidant enzymes induced by ammonia intoxication. Metab Brain Dis 13:28–41
    • (1998) Metab Brain Dis , vol.13 , pp. 28-41
    • Kosenko, E.1    Kaminsky, Y.2    Lopata, O.3    Muravyov, N.4    Kaminsky, A.5    Hermenegildo, C.6    Felipo, V.7
  • 17
    • 4444287083 scopus 로고    scopus 로고
    • Fulminant hepatic failure induced oxidative stress in nonsynaptic mitochondria of cerebral cortex in rats
    • COI: 1:CAS:528:DC%2BD2cXntlSlsLk%3D, PID: 15342125
    • Reddy PV, Murthy ChR, Reddanna P (2004) Fulminant hepatic failure induced oxidative stress in nonsynaptic mitochondria of cerebral cortex in rats. Neurosci Lett 368:15–20
    • (2004) Neurosci Lett , vol.368 , pp. 15-20
    • Reddy, P.V.1    Murthy, C.R.2    Reddanna, P.3
  • 18
    • 84893621843 scopus 로고    scopus 로고
    • Oxidative stress and tissue pathology caused by subacute exposure to ammonium acetate in rats and their response to treatments with alpha-ketoglutarate and N-acetyl cysteine
    • PID: 22661398
    • Satpute RM, Lomash V, Hariharakrishnan J, Rao P, Singh P, Gujar NL, Bhattacharya R (2012) Oxidative stress and tissue pathology caused by subacute exposure to ammonium acetate in rats and their response to treatments with alpha-ketoglutarate and N-acetyl cysteine. Toxicol Ind Health. doi:10.1177/0748233712448117
    • (2012) Toxicol Ind Health
    • Satpute, R.M.1    Lomash, V.2    Hariharakrishnan, J.3    Rao, P.4    Singh, P.5    Gujar, N.L.6    Bhattacharya, R.7
  • 19
    • 20944435890 scopus 로고    scopus 로고
    • Emerging roles of thioredoxin cycles enzymes in the central nervous system
    • COI: 1:CAS:528:DC%2BD2MXhtFCgtLvO, PID: 15761666
    • Patenaude A, Murthy MRV, Mirault ME (2005) Emerging roles of thioredoxin cycles enzymes in the central nervous system. Cell Mol Life Sci 62:1063–1080
    • (2005) Cell Mol Life Sci , vol.62 , pp. 1063-1080
    • Patenaude, A.1    Murthy, M.R.V.2    Mirault, M.E.3
  • 20
    • 4444335186 scopus 로고    scopus 로고
    • Thioredoxin as a neurotrophic cofactor and an important regulator of neuroprotection
    • COI: 1:CAS:528:DC%2BD2cXltlKku78%3D, PID: 15181236
    • Masutani H, Bai J, Kim YC, Yodoi J (2004) Thioredoxin as a neurotrophic cofactor and an important regulator of neuroprotection. Mol Neurobiol 29:229–242
    • (2004) Mol Neurobiol , vol.29 , pp. 229-242
    • Masutani, H.1    Bai, J.2    Kim, Y.C.3    Yodoi, J.4
  • 21
    • 33845428642 scopus 로고    scopus 로고
    • Thioredoxin and related molecules—from biology to health and disease
    • Lilling CH, Holmgren A (2007) Thioredoxin and related molecules—from biology to health and disease. Antioxid Redox Signal 9:25–47
    • (2007) Antioxid Redox Signal , vol.9 , pp. 25-47
    • Lilling, C.H.1    Holmgren, A.2
  • 22
    • 84876917760 scopus 로고    scopus 로고
    • Thioredoxins, glutaredoxins, and peroxiredoxins—molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling
    • COI: 1:CAS:528:DC%2BC3sXhs1eks7zF
    • Hanschmann EM, Godoy JR, Berndt C, Hudemann C, Lillig CH (2013) Thioredoxins, glutaredoxins, and peroxiredoxins—molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling. Antiox Redox Signal 19:1539–1605
    • (2013) Antiox Redox Signal , vol.19 , pp. 1539-1605
    • Hanschmann, E.M.1    Godoy, J.R.2    Berndt, C.3    Hudemann, C.4    Lillig, C.H.5
  • 23
    • 75649096002 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein links oxidative stress to inflammasome activation
    • COI: 1:CAS:528:DC%2BD1MXhsFyhsLrJ, PID: 20023662
    • Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J (2010) Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 11:136–141
    • (2010) Nat Immunol , vol.11 , pp. 136-141
    • Zhou, R.1    Tardivel, A.2    Thorens, B.3    Choi, I.4    Tschopp, J.5
  • 24
    • 77955494531 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein (Txnip) gene expression. Sensing oxidative phosphorylation status and glycolytic rate
    • COI: 1:CAS:528:DC%2BC3cXpslKju7s%3D, PID: 20558747
    • Yu FX, Chai TF, He H, Hagen T, Lou Y (2010) Thioredoxin-interacting protein (Txnip) gene expression. Sensing oxidative phosphorylation status and glycolytic rate. J Biol Chem 285:25822–25830
    • (2010) J Biol Chem , vol.285 , pp. 25822-25830
    • Yu, F.X.1    Chai, T.F.2    He, H.3    Hagen, T.4    Lou, Y.5
  • 26
    • 77749237129 scopus 로고    scopus 로고
    • Brain edema in acute liver failure. Inhibition by l-histidine
    • PID: 20075201
    • Rama Rao KV, Reddy PVB, Tong X, Norenberg MD (2010) Brain edema in acute liver failure. Inhibition by l-histidine. Am J Pathol 176:1400–1408
    • (2010) Am J Pathol , vol.176 , pp. 1400-1408
    • Rama Rao, K.V.1    Reddy, P.V.B.2    Tong, X.3    Norenberg, M.D.4
  • 27
    • 33750608704 scopus 로고    scopus 로고
    • Glutamine: a Trojan horse in ammonia neurotoxicity
    • COI: 1:CAS:528:DC%2BD28XhtFyqsr%2FI, PID: 17006913
    • Albrecht J, Norenberg MD (2006) Glutamine: a Trojan horse in ammonia neurotoxicity. Hepatology 44:788–794
    • (2006) Hepatology , vol.44 , pp. 788-794
    • Albrecht, J.1    Norenberg, M.D.2
  • 28
    • 0028045735 scopus 로고
    • Brain ion and amino acid contents during edema development in hepatic encephalopathy
    • COI: 1:CAS:528:DyaK2cXhtVeqs7s%3D, PID: 8263520
    • Hilgier W, Olson J (1994) Brain ion and amino acid contents during edema development in hepatic encephalopathy. J Neurochem 62:197–204
    • (1994) J Neurochem , vol.62 , pp. 197-204
    • Hilgier, W.1    Olson, J.2
  • 29
    • 0021803196 scopus 로고
    • The selenoenzyme phospholipid hydroperoxide glutathione peroxidase
    • COI: 1:CAS:528:DyaL2MXktFyku7s%3D, PID: 3978121
    • Ursini F, Maiorino M, Gregolin C (1985) The selenoenzyme phospholipid hydroperoxide glutathione peroxidase. Biochim Biophys Acta 839:62–70
    • (1985) Biochim Biophys Acta , vol.839 , pp. 62-70
    • Ursini, F.1    Maiorino, M.2    Gregolin, C.3
  • 30
    • 85062523222 scopus 로고    scopus 로고
    • Measurement of thioredoxin and thioredoxin reductase. Curr Protoc Toxicol Chapter 7
    • Arner ESJ, Holmgren A (2000) Measurement of thioredoxin and thioredoxin reductase. Curr Protoc Toxicol Chapter 7, Unit 7.4
    • (2000) Unit , vol.7 , pp. 4
    • Arner, E.S.J.1    Holmgren, A.2
  • 31
    • 0032824908 scopus 로고    scopus 로고
    • Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by TPA, a calcium ionophore and other tumor promoters
    • COI: 1:CAS:528:DyaK1MXlvFWqsbg%3D, PID: 10469622
    • Kumar S, Holmgren A (1999) Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by TPA, a calcium ionophore and other tumor promoters. Carcinogenesis 20:1761–1767
    • (1999) Carcinogenesis , vol.20 , pp. 1761-1767
    • Kumar, S.1    Holmgren, A.2
  • 32
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanatephenol–chloroform extraction
    • COI: 1:CAS:528:DyaL2sXitFSns7Y%3D, PID: 2440339
    • Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanatephenol–chloroform extraction. Anal Biochem 162:156–159
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 33
    • 0035710746 scopus 로고    scopus 로고
    • −ΔΔCt method
    • COI: 1:CAS:528:DC%2BD38XhtFelt7s%3D, PID: 11846609
    • −ΔΔCt method. Methods 25:402–408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 34
    • 12244291916 scopus 로고    scopus 로고
    • Peroxide detoxification by brain cells
    • COI: 1:CAS:528:DC%2BD2MXltlCltg%3D%3D, PID: 15573410
    • Dringen R, Pawlowski PG, Hirrlinger J (2005) Peroxide detoxification by brain cells. J Neurosci Res 79:157–165
    • (2005) J Neurosci Res , vol.79 , pp. 157-165
    • Dringen, R.1    Pawlowski, P.G.2    Hirrlinger, J.3
  • 35
    • 61649088812 scopus 로고    scopus 로고
    • The role of antioxidants and antioxidant-related enzymes in protective responses to environmentally induced oxidative stress
    • PID: 18955158
    • Limón-Pacheco J, Gonsebatt ME (2009) The role of antioxidants and antioxidant-related enzymes in protective responses to environmentally induced oxidative stress. Mutat Res 674:137–147
    • (2009) Mutat Res , vol.674 , pp. 137-147
    • Limón-Pacheco, J.1    Gonsebatt, M.E.2
  • 36
    • 36948999820 scopus 로고    scopus 로고
    • Acute and chronic hyperammonemia modulate antioxidant enzymes differently in cerebral cortex and cerebellum
    • COI: 1:CAS:528:DC%2BD2sXhsVSmurzF, PID: 17676388
    • Singh S, Koiri RK, Trigun SK (2008) Acute and chronic hyperammonemia modulate antioxidant enzymes differently in cerebral cortex and cerebellum. Neurochem Res 33:103–113
    • (2008) Neurochem Res , vol.33 , pp. 103-113
    • Singh, S.1    Koiri, R.K.2    Trigun, S.K.3
  • 38
    • 78651349039 scopus 로고    scopus 로고
    • Expression of Keap1-Nrf2 system and antioxidant proteins in mouse brain after transient middle cerebral artery occlusion
    • COI: 1:CAS:528:DC%2BC3MXktFShtg%3D%3D, PID: 21075092
    • Tanaka N, Ikeda Y, Ohta Y, Deguchi K, Tian F, Shang J, Matsuura T, Abe K (2011) Expression of Keap1-Nrf2 system and antioxidant proteins in mouse brain after transient middle cerebral artery occlusion. Brain Res 1370:246–253
    • (2011) Brain Res , vol.1370 , pp. 246-253
    • Tanaka, N.1    Ikeda, Y.2    Ohta, Y.3    Deguchi, K.4    Tian, F.5    Shang, J.6    Matsuura, T.7    Abe, K.8
  • 39
    • 0033969616 scopus 로고    scopus 로고
    • Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer’s disease brain
    • COI: 1:CAS:528:DC%2BD3cXhsVantLw%3D, PID: 10699754
    • Lovell MA, Xie C, Gabbita P, Markesbery WR (2000) Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer’s disease brain. Free Radic Biol Med 28:418–427
    • (2000) Free Radic Biol Med , vol.28 , pp. 418-427
    • Lovell, M.A.1    Xie, C.2    Gabbita, P.3    Markesbery, W.R.4
  • 40
    • 0033828495 scopus 로고    scopus 로고
    • Thioredoxin reductase and glutathione synthesis is upregulated by t-butylhydroquinone in cortical astrocytes but not in cortical neurons
    • COI: 1:STN:280:DC%2BD3cvpsFKrsw%3D%3D, PID: 10941150
    • Eftekharpour E, Holmgren A, Juurlink BHJ (2000) Thioredoxin reductase and glutathione synthesis is upregulated by t-butylhydroquinone in cortical astrocytes but not in cortical neurons. Glia 31:241–248
    • (2000) Glia , vol.31 , pp. 241-248
    • Eftekharpour, E.1    Holmgren, A.2    Juurlink, B.H.J.3
  • 41
    • 0027436461 scopus 로고
    • Astroglial expression of ATL-derived factor, a human thioredoxin homologue, in gerbil brain after transient global ischemia
    • COI: 1:CAS:528:DyaK2cXmtFGn, PID: 7694770
    • Tomimoto H, Akiguchi I, Wakita H, Kimura J, Hori K, Yodoi J (1993) Astroglial expression of ATL-derived factor, a human thioredoxin homologue, in gerbil brain after transient global ischemia. Brain Res 625:1–8
    • (1993) Brain Res , vol.625 , pp. 1-8
    • Tomimoto, H.1    Akiguchi, I.2    Wakita, H.3    Kimura, J.4    Hori, K.5    Yodoi, J.6
  • 42
    • 0028234644 scopus 로고
    • Neuroprotectection by glia cells through adult T cell leukemia-derived factor/human thioredoxin (ADF/TRX)
    • COI: 1:CAS:528:DyaK2cXltVGqs7g%3D, PID: 7953744
    • Hori K, Katayama M, Sato N, Ishii K, Waga S, Yodoi J (1994) Neuroprotectection by glia cells through adult T cell leukemia-derived factor/human thioredoxin (ADF/TRX). Brain Res 652:304–310
    • (1994) Brain Res , vol.652 , pp. 304-310
    • Hori, K.1    Katayama, M.2    Sato, N.3    Ishii, K.4    Waga, S.5    Yodoi, J.6
  • 43
    • 84875697554 scopus 로고    scopus 로고
    • Glutathione peroxidases
    • COI: 1:CAS:528:DC%2BC3sXotFWn, PID: 23201771
    • Brigelius-Flohe R, Maiorino M (2013) Glutathione peroxidases. Biochim Biophys Acta 1830:3289–3303
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 3289-3303
    • Brigelius-Flohe, R.1    Maiorino, M.2
  • 44
    • 0015880169 scopus 로고
    • Glutathione peroxidase: a selenoenzyme
    • PID: 4736708
    • Flohé L, Günzler WA, Schock HH (1973) Glutathione peroxidase: a selenoenzyme. FEBS Lett 32:132–134
    • (1973) FEBS Lett , vol.32 , pp. 132-134
    • Flohé, L.1    Günzler, W.A.2    Schock, H.H.3
  • 45
    • 84862309967 scopus 로고    scopus 로고
    • Selenium regulation of the selenoprotein and nonselenoprotein transcriptomes in rodents
    • COI: 1:CAS:528:DC%2BC3MXpsF2lu7Y%3D, PID: 22332043
    • Sunde RA, Raines AM (2011) Selenium regulation of the selenoprotein and nonselenoprotein transcriptomes in rodents. Adv Nutr 2:138–150
    • (2011) Adv Nutr , vol.2 , pp. 138-150
    • Sunde, R.A.1    Raines, A.M.2
  • 46
    • 84879103447 scopus 로고    scopus 로고
    • Gene Expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy
    • PID: 23325665
    • Görg B, Bidmon HJ, Häussinger D (2013) Gene Expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy. Hepatology 57:2436–2447
    • (2013) Hepatology , vol.57 , pp. 2436-2447
    • Görg, B.1    Bidmon, H.J.2    Häussinger, D.3
  • 48
    • 70349290632 scopus 로고    scopus 로고
    • Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity
    • COI: 1:CAS:528:DC%2BD1MXhtFGrt7%2FJ, PID: 19706488
    • Kaadige MR, Looper RE, Kamalanaadhan S, Donald EA (2009) Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity. PNAS 106:14878–14883
    • (2009) PNAS , vol.106 , pp. 14878-14883
    • Kaadige, M.R.1    Looper, R.E.2    Kamalanaadhan, S.3    Donald, E.A.4
  • 51
    • 0032104360 scopus 로고    scopus 로고
    • Antioxidant characteristics of L-histidine
    • COI: 1:CAS:528:DyaK1cXjvF2ns7o%3D
    • Wade MA, Tucker HN (1998) Antioxidant characteristics of L-histidine. J Nutr Biochem 9:308–315
    • (1998) J Nutr Biochem , vol.9 , pp. 308-315
    • Wade, M.A.1    Tucker, H.N.2
  • 52
    • 77954537847 scopus 로고    scopus 로고
    • Histidine, cystine, glutamine, and threonine collectively protect astrocytes from the toxicity of zinc
    • COI: 1:CAS:528:DC%2BC3cXoslWrsLc%3D, PID: 20570723
    • Ralph DM, Robinson SR, Campbell MS, Bishop GM (2010) Histidine, cystine, glutamine, and threonine collectively protect astrocytes from the toxicity of zinc. Free Radic Biol Med 49:649–657
    • (2010) Free Radic Biol Med , vol.49 , pp. 649-657
    • Ralph, D.M.1    Robinson, S.R.2    Campbell, M.S.3    Bishop, G.M.4
  • 53
    • 0034859820 scopus 로고    scopus 로고
    • Oxidation of zinc finger transcription factors: physiological consequences
    • COI: 1:CAS:528:DC%2BD3MXmtlCrtr4%3D, PID: 11554443
    • Webster KA, Prentice H, Bishopric NH (2001) Oxidation of zinc finger transcription factors: physiological consequences. Antioxid Redox Signal 3:535–548
    • (2001) Antioxid Redox Signal , vol.3 , pp. 535-548
    • Webster, K.A.1    Prentice, H.2    Bishopric, N.H.3
  • 54
    • 18244377997 scopus 로고    scopus 로고
    • Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein
    • COI: 1:CAS:528:DC%2BD2MXjt1Oktbg%3D, PID: 15865434
    • Dinkova-Kostova AT, Holtzclaw WD, Wakabayashi N (2005) Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein. Biochemistry 44:6889–6899
    • (2005) Biochemistry , vol.44 , pp. 6889-6899
    • Dinkova-Kostova, A.T.1    Holtzclaw, W.D.2    Wakabayashi, N.3
  • 55
    • 15044349930 scopus 로고    scopus 로고
    • Effect of metal complexes on thioredoxin reductase and the regulation of mitochondrial permeability conditions
    • Bragadin M, Scutari G, Folda A, Bindoli A, Rigobello MP (2004) Effect of metal complexes on thioredoxin reductase and the regulation of mitochondrial permeability conditions. Ann NY Acad Sci 1030:248–354
    • (2004) Ann NY Acad Sci , vol.1030 , pp. 248-354
    • Bragadin, M.1    Scutari, G.2    Folda, A.3    Bindoli, A.4    Rigobello, M.P.5
  • 56
    • 80755169614 scopus 로고    scopus 로고
    • Ammonia increases nitric oxide, free Zn(2+), and metallothionein mRNA expression in cultured rat astrocytes
    • COI: 1:CAS:528:DC%2BC38XivFSrtb0%3D, PID: 22050230
    • Kruczek C, Görg B, Keitel V, Bidmon HJ, Schliess F, Häussinger D (2011) Ammonia increases nitric oxide, free Zn(2+), and metallothionein mRNA expression in cultured rat astrocytes. Biol Chem 392:1155–1165
    • (2011) Biol Chem , vol.392 , pp. 1155-1165
    • Kruczek, C.1    Görg, B.2    Keitel, V.3    Bidmon, H.J.4    Schliess, F.5    Häussinger, D.6
  • 57
    • 77956393999 scopus 로고    scopus 로고
    • Mechanisms, diagnosis and management of hepatic encephalopathy
    • PID: 20703237
    • Prakash R, Mullen KD (2010) Mechanisms, diagnosis and management of hepatic encephalopathy. Nat Rev Gastroenterol Hepatol 7:515–525
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , pp. 515-525
    • Prakash, R.1    Mullen, K.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.